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Ojas A. Namjoshi · SciRah

Researcher profile · Semantic Scholar

Ojas A. Namjoshi

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Ojas A. Namjoshi — researcher profile on SciRah

h-index: 19
Works: 46
Citations: 968

Most-cited papers

Oxymatrine Attenuates Tumor Growth and Deactivates STAT5 Signaling in a Lung Cancer Xenograft Model
Young Y. Jung, Muthu K. Shanmugam, A. Narula, Chulwon Kim +5 more
2019Cancers108 citations Open access
Semantic Scholar
Anti-myeloma Effects of Icariin Are Mediated Through the Attenuation of JAK/STAT3-Dependent Signaling Cascade
Young Y. Jung, Jong Hyun Lee, D. Nam, A. Narula +5 more
2018Frontiers in Pharmacology77 citations Open access
Semantic Scholar
Dihydrofolate reductase as a target for chemotherapy in parasites.
A. Gangjee, Sonali Kurup, Ojas A. Namjoshi
2007Current pharmaceutical design68 citations
Semantic Scholar
Brønsted Acid Mediated Cyclization of Enaminones. Rapid and Efficient Access to the Tetracyclic Framework of the Strychnos Alkaloids
Rahul V. Edwankar, Chitra R. Edwankar, Ojas A. Namjoshi, J. Deschamps +1 more
2012Journal of Natural Products57 citations Open access
Semantic Scholar
Design, synthesis and molecular modeling of novel pyrido[2,3-d]pyrimidine analogs as antifolates: Application of Buchwald-Hartwig aminations of heterocycles
A. Gangjee, Ojas A. Namjoshi, Sudhir Raghavan, S. Queener +2 more
2013Journal of Medicinal Chemistry43 citations Open access
Semantic Scholar
Stereospecific Approach to the Synthesis of Ring-A Oxygenated Sarpagine Indole Alkaloids. Total Synthesis of the Dimeric Indole Alkaloid P-(+)-Dispegatrine and Six Other Monomeric Indole Alkaloids
Chitra R. Edwankar, Rahul V. Edwankar, Ojas A. Namjoshi, X. Liao +1 more
2013Journal of Organic Chemistry42 citations Open access
Semantic Scholar
Design, Synthesis and Subtype Selectivity of 3, 6-Disubstituted β-Carbolines at Bz/GABA(A)ergic Receptors. SAR and Studies Directed Toward Agents For Treatment of Alcohol Abuse
W. Yin, Samarpan Majumder, T. Clayton, S. Petrou +7 more
2010Bioorganic & Medicinal Chemistry35 citations Open access
Semantic Scholar
Cognition-Impairing Effects of Benzodiazepine-Type Drugs: Role of GABAA Receptor Subtypes in an Executive Function Task in Rhesus Monkeys
Leah Makaron, C. Moran, Ojas A. Namjoshi, S. Rallapalli +2 more
2013Pharmacology, Biochemistry and Behavior34 citations Open access
Semantic Scholar
Design, Synthesis, and Preclinical Evaluation of 4-Substituted-5-methyl-furo[2,3-d]pyrimidines as Microtubule Targeting Agents That Are Effective against Multidrug Resistant Cancer Cells
R. K. V. Devambatla, Ojas A. Namjoshi, Shruti Choudhary, E. Hamel +4 more
2016Journal of Medicinal Chemistry33 citations Open access
Semantic Scholar
Evodiamine Mitigates Cellular Growth and Promotes Apoptosis by Targeting the c-Met Pathway in Prostate Cancer Cells
S. Hwang, J. Um, A. Chinnathambi, S. Alharbi +4 more
2020Molecules31 citations Open access
Semantic Scholar
Design, synthesis and biological evaluation of substituted pyrrolo[2,3-d]pyrimidines as multiple receptor tyrosine kinase inhibitors and antiangiogenic agents.
A. Gangjee, Ojas A. Namjoshi, Jianming Yu, M. Ihnat +2 more
2008Bioorganic & Medicinal Chemistry30 citations Open access
Semantic Scholar
Withanolide modulates the potential crosstalk between apoptosis and autophagy in different colorectal cancer cell lines.
Young Y. Jung, J. Um, A. Chinnathambi, Chandramohan Govindasamy +5 more
2022European Journal of Pharmacology27 citations
Semantic Scholar
2,3,5,6-Tetramethylpyrazine Targets Epithelial-Mesenchymal Transition by Abrogating Manganese Superoxide Dismutase Expression and TGFβ-Driven Signaling Cascades in Colon Cancer Cells
Young Y. Jung, C. D. Mohan, Huiyan Eng, A. Narula +6 more
2022Biomolecules25 citations Open access
Semantic Scholar
Tanshinone IIA exerts autophagic cell death through down-regulation of β-catenin in renal cell carcinoma cells.
Na-Young Kim, Young Y. Jung, Min-Hee Yang, A. Chinnathambi +5 more
2022Biochimie24 citations
Semantic Scholar
The natural analgesic conolidine targets the newly identified opioid scavenger ACKR3/CXCR7
M. Szpakowska, Ann M. Decker, M. Meyrath, Christie B. Palmer +3 more
2021Signal Transduction and Targeted Therapy23 citations Open access
Semantic Scholar
Sarpagine and related alkaloids
Ojas A. Namjoshi, J. Cook
2015The Alkaloids: Chemistry and Biology23 citations Open access
Semantic Scholar
The dopamine, serotonin and norepinephrine releasing activities of a series of methcathinone analogs in male rat brain synaptosomes
B. Blough, Ann M. Decker, A. Landavazo, Ojas A. Namjoshi +3 more
2018Psychopharmacology21 citations Open access
Semantic Scholar
First stereospecific total synthesis of (-)-affinisine oxindole as well as facile entry into the C(7)-diastereomeric chitosenine stereochemistry
G. Fonseca, Zhi-jian Wang, Ojas A. Namjoshi, J. Deschamps +1 more
201521 citations
Semantic Scholar
Development of a Two-step Route to 3-PBC and βCCt, Two Agents Active Against Alcohol Self-Administration in Rodent and Primate Models
Ojas A. Namjoshi, Angelica Gryboski, G. Fonseca, M. V. VanLinn +3 more
2011Journal of Organic Chemistry21 citations Open access
Semantic Scholar
Triple monoamine uptake inhibitors demonstrate a pharmacologic association between excessive drinking and impulsivity in high alcohol-preferring (HAP) mice
D. O’Tousa, K. Warnock, Liana M. Matson, Ojas A. Namjoshi +6 more
2013Addiction Biology17 citations Open access
Semantic Scholar
Recent progress in the total synthesis of indole alkaloids.
Chitra R. Edwankar, Rahul V. Edwankar, Ojas A. Namjoshi, S. Rallapalli +2 more
2009Current opinion in drug discovery & development17 citations
Semantic Scholar
Identification of Matrine as a Novel Regulator of the CXCR4 Signaling Axis in Tumor Cells
Young Y. Jung, J. Um, A. Narula, Ojas A. Namjoshi +3 more
2020International Journal of Molecular Sciences16 citations Open access
Semantic Scholar
N2-Trimethylacetyl substituted and unsubstituted-N4-phenylsubstituted-6-(2-pyridin-2-ylethyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamines: Design, cellular receptor tyrosine kinase inhibitory activities and in vivo evaluation as antiangiogenic, antimetastatic and antitumor agents
A. Gangjee, Ojas A. Namjoshi, Jianming Yu, M. Ihnat +2 more
2013Bioorganic & Medicinal Chemistry16 citations Open access
Semantic Scholar
Search for α3β2/3γ2 Subtype Selective Ligands That are Stable on Human Liver Microsomes
Ojas A. Namjoshi, Zhi-jian Wang, S. Rallapalli, E. Johnson +9 more
2012Bioorganic & Medicinal Chemistry16 citations Open access
Semantic Scholar
Structure-activity correlations for three pyrido[2,3-d]pyrimidine antifolates binding to human and Pneumocystis carinii dihydrofolate reductase.
V. Cody, J. Pace, Ojas A. Namjoshi, A. Gangjee
2015Acta Crystallographica Section F Structural Biology Communications15 citations Open access
Semantic Scholar
SH-I-048A, AN IN VITRO NONSELECTIVE SUPER-AGONIST AT THE BENZODIAZEPINE SITE OF GABAA RECEPTORS: THE APPROXIMATED ACTIVATION OF RECEPTOR SUBTYPES MAY EXPLAIN BEHAVIORAL EFFECTS
A. Obradovic, Srđan Joksimović, M. Poe, J. Ramerstorfer +9 more
2014Brain Research15 citations Open access
Semantic Scholar
Role of gamma-aminobutyric acid type A (GABAA) receptor subtypes in acute benzodiazepine physical dependence-like effects: evidence from squirrel monkeys responding under a schedule of food presentation
Bradford D. Fischer, L. P. Teixeira, M. V. VanLinn, Ojas A. Namjoshi +2 more
2013Psychopharmacology15 citations Open access
Semantic Scholar
2-Amino-4-methyl-5-phenylethyl substituted-7-N-benzyl-pyrrolo[2,3-d]pyrimidines as novel antitumor antimitotic agents that also reverse tumor resistance
A. Gangjee, Ojas A. Namjoshi, S. Keller, Charles D. Smith
2011Bioorganic & Medicinal Chemistry15 citations Open access
Semantic Scholar
Duration of treatment and activation of α1-containing GABAA receptors variably affect the level of anxiety and seizure susceptibility after diazepam withdrawal in rats
J. Kovačević, T. Timić, Veera Venkata Naga Phani Babu Tiruveedhula, B. Batinić +5 more
2014Brain Research Bulletin14 citations Open access
Semantic Scholar
Little evidence of a role for the α1 GABAA subunit-containing receptor in a rhesus monkey model of alcohol drinking
E. Sawyer, C. Moran, Madelynn H. Sirbu, Melissa Szafir +5 more
2013Alcoholism: Clinical and Experimental Research13 citations Open access
Semantic Scholar
Potential function of oxymatrine as a novel suppressor of epithelial-to-mesenchymal transition in lung tumor cells.
Young Y. Jung, S. Baek, A. Narula, Ojas A. Namjoshi +2 more
2021Life Science12 citations
Semantic Scholar
Berbamine Analogs Exhibit Differential Protective Effects From Aminoglycoside-Induced Hair Cell Death
Alexandria M. Hudson, Gavin Lockard, Ojas A. Namjoshi, Joseph W. Wilson +3 more
2020Frontiers in Cellular Neuroscience12 citations Open access
Semantic Scholar
Antagonism of triazolam self-administration in rhesus monkeys responding under a progressive-ratio schedule: In vivo apparent pA2 analysis
Bradford D. Fischer, D. Platt, S. Rallapalli, Ojas A. Namjoshi +2 more
2015Drug and Alcohol Dependence10 citations Open access
Semantic Scholar
The contribution of a 2-amino group on receptor tyrosine kinase inhibition and antiangiogenic activity in 4-anilinosubstituted pyrrolo[2,3-d]pyrimidines
A. Gangjee, Ojas A. Namjoshi, M. Ihnat, Aaron Buchanan
2010Bioorganic & Medicinal Chemistry Letters9 citations Open access
Semantic Scholar
Stereospecific Total Synthesis of the Indole Alkaloid Ervincidine. Establishment of the C-6 Hydroxyl Stereochemistry
S. Rallapalli, Ojas A. Namjoshi, V. V. N. P. B. Tiruveedhula, J. Deschamps +1 more
2014Journal of Organic Chemistry5 citations Open access
Semantic Scholar
TMP: A dual modulator of apoptosis and autophagy via SHP-1 regulation in hepatocellular carcinoma.
Young Y. Jung, Ye-jin Hong, Dongwoo Nam, A. Deivasigamani +8 more
2024Life Science3 citations Open access
Semantic Scholar
Small Molecule Neuropeptide S and Melanocortin 4 Receptor Ligands as Potential Treatments for Substance Use Disorders.
B. Blough, Ojas A. Namjoshi
2019Handbook of Experimental Pharmacology2 citations
Semantic Scholar
Evidence for sedative effects of benzodiazepines involving unexpected GABAA receptor subtypes
J. Rowlett, Angela N. Duke, D. Platt, Ojas A. Namjoshi +3 more
20152 citations
Semantic Scholar
Role of α3GABAA receptor modulation in the anti-conflict effects of benzodiazepine-type drugs in monkeys
E. Sawyer, Bradford D. Fischer, Zhi-Qiang Meng, M. Poe +3 more
20142 citations
Semantic Scholar
Chemical modifications to alter monoamine releasing activity of phenmetrazine analogs as potential treatments of stimulant addiction
Ojas A. Namjoshi, Ann M. Decker, A. Landavazo, J. Partilla +3 more
20150 citations
Semantic Scholar
Search for alpha 3 beta 2/3 gamma 2 subtype selective ligands that are stable on human liver microsomes
Ojas A. Namjoshi, Zhi-jian Wang, S. Rallapalli, E. Johnson +8 more
20120 citations
Semantic Scholar
βCCT, AN ANTAGONIST SELECTIVE FOR α1 GABAA RECEPTORS, REVERSES DIAZEPAM WITHDRAWAL-INDUCED ANXIETY IN RATS
J. Divljaković, M. Milić, Ojas A. Namjoshi, Veera Venkata Naga Phani Babu Tiruveedhula +3 more
2012Brain Research Bulletin0 citations Open access
Semantic Scholar
A Very Active Cu‐Catalytic System for the Synthesis of Aryl, Heteroaryl, and Vinyl Sulfides.
M. S. Kabir, M. Lorenz, M. V. VanLinn, Ojas A. Namjoshi +2 more
20100 citations
Semantic Scholar
A New Ligand for Copper-Catalyzed Cross-Coupling of Heterocyclesand Phenols
M. S. Kabir, M. Lorenz, Ojas A. Namjoshi, J. Cook
20100 citations
Semantic Scholar
The Synthesis of pyrrolo[2,3-d]pyrimidines and pyrido[2,3-d]pyrimidines as receptor tyrosine kinase inhibitors or tubulin inhibitors or inhibitors of dihydrofolate reductases and the development of inhibitors or inhibitors of dihydrofolate reductases and the development of metal-catalyzed cross-coup
Ojas A. Namjoshi
20090 citations
Semantic Scholar
Effect of a 2-amino group on receptor tyrosine kinase inhibition and antiangiogenic activity of 4-anilinosubstituted pyrrolo[2,3-d]pyrimidines
Ojas A. Namjoshi, A. Gangjee, M. Ihnat, M. Todd
20060 citations
Semantic Scholar

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