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V. Cody · SciRah

Researcher profile · Semantic Scholar

V. Cody

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V. Cody — researcher profile on SciRah

h-index: 33
Works: 273
Citations: 4,109

Most-cited papers

Membrane receptors mediating thyroid hormone action.
P. Davis, F. Davis, V. Cody
2005Trends in endocrinology and metabolism177 citations
Semantic Scholar
Protein and RNA dynamical fingerprinting
K. Niessen, Meng-Yang Xu, D. George, Michael C. Chen +6 more
2019Nature Communications103 citations Open access
Semantic Scholar
Molecular modeling of the thyroid hormone interactions with αvβ3 integrin
V. Cody, P. Davis, F. Davis
2007103 citations
Semantic Scholar
Understanding the role of Leu22 variants in methotrexate resistance: comparison of wild-type and Leu22Arg variant mouse and human dihydrofolate reductase ternary crystal complexes with methotrexate and NADPH.
V. Cody, J. Luft, W. Pangborn
2005Acta Crystallographica Section D: Biological Crystallography101 citations
Semantic Scholar
Faculty Opinions recommendation of FTIR reveals structural differences between native beta-sheet proteins and amyloid fibrils.
V. Cody
200576 citations Open access
Semantic Scholar
Identification and functions of the plasma membrane receptor for thyroid hormone analogues.
Hung-Yun Lin, V. Cody, F. Davis, A. Hercbergs +3 more
2011Discover medicine66 citations
Semantic Scholar
Chemically Self-assembled Antibody Nanorings (CSANs): Design and Characterization of an Anti-CD3 IgM Biomimetic
Qing Li, Christopher R. So, Adrian Fegan, V. Cody +3 more
2010Journal of the American Chemical Society66 citations Open access
Semantic Scholar
SLIDING CLAMP-DNA INTERACTIONS ARE REQUIRED FOR VIABILITY AND CONTRIBUTE TO DNA POLYMERASE MANAGEMENT IN Escherichia coli
Justin M. H. Heltzel, Sarah K. Scouten Ponticelli, Laurie H. Sanders, J. Duzen +4 more
2009Journal of Molecular Biology60 citations Open access
Semantic Scholar
Structural characteristics of antifolate dihydrofolate reductase enzyme interactions
V. Cody, C. Schwalbe
200651 citations
Semantic Scholar
Design, Synthesis, and X-ray Crystal Structure of Classical and Nonclassical 2-Amino-4-oxo-5-substituted-6-ethyl-thieno[2,3-d]pyrimidines as Dual Thymidylate Synthase and Dihydrofolate Reductase Inhibitors and as Potential Antitumor Agents
A. Gangjee, Wei Li, R. Kisliuk, V. Cody +3 more
2009Journal of Medicinal Chemistry47 citations Open access
Semantic Scholar
Trimethoprim Resistance of Dihydrofolate Reductase Variants from Clinical Isolates of Pneumocystis jirovecii
S. Queener, V. Cody, J. Pace, P. Torkelson +1 more
2013Antimicrobial Agents and Chemotherapy46 citations Open access
Semantic Scholar
Design, synthesis and molecular modeling of novel pyrido[2,3-d]pyrimidine analogs as antifolates: Application of Buchwald-Hartwig aminations of heterocycles
A. Gangjee, Ojas A. Namjoshi, Sudhir Raghavan, S. Queener +2 more
2013Journal of Medicinal Chemistry43 citations Open access
Semantic Scholar
Small Molecule Hormone or Hormone-Like Ligands of Integrin αVβ3: Implications for Cancer Cell Behavior
P. Davis, S. Mousa, V. Cody, Heng-Yuan Tang +1 more
2013Hormones & cancer41 citations Open access
Semantic Scholar
Molecular modeling of the thyroid hormone interactions with alpha v beta 3 integrin.
V. Cody, P. Davis, F. Davis
2007Steroids36 citations
Semantic Scholar
Combined QM/MM Study of Thyroid and Steroid Hormone Analogue Interactions with αvβ3 Integrin
M. Freindorf, T. Furlani, Jing Kong, V. Cody +2 more
2012Journal of Biomedicine and Biotechnology35 citations Open access
Semantic Scholar
New insights into DHFR interactions: Analysis of Pneumocystis carinii and mouse DHFR complexes with NADPH and two highly potent 5‐(ω‐carboxy(alkyloxy) trimethoprim derivatives reveals conformational correlations with activity and novel parallel ring stacking interactions
V. Cody, J. Pace, Kim Chisum, A. Rosowsky
2006Proteins: Structure, Function, and Bioinformatics35 citations
Semantic Scholar
Design, Synthesis, and X-ray Crystal Structures of 2,4-Diaminofuro[2,3-d]pyrimidines as Multireceptor Tyrosine Kinase and Dihydrofolate Reductase Inhibitors
A. Gangjee, Wei Li, Lu Lin, Yibin Zeng +6 more
2009Bioorganic & Medicinal Chemistry34 citations Open access
Semantic Scholar
Recent advances in transthyretin evolution, structure, and biological functions /
S. Richardson, V. Cody
200933 citations
Semantic Scholar
Conformational analysis of aromatic amino acids by x-ray crystallography.
V. Cody, W. Duax, H. Hauptman
2009International journal of peptide & protein research33 citations
Semantic Scholar
A Novel Mutation in the Albumin Gene (R218S) Causing Familial Dysalbuminemic Hyperthyroxinemia in a Family of Bangladeshi Extraction
S. Greenberg, A. M. Ferrara, Everton S. Nicholas, A. Dumitrescu +3 more
2014Thyroid29 citations Open access
Semantic Scholar
Correlations of Inhibitor Kinetics for Pneumocystis jirovecii and Human Dihydrofolate Reductase with Structural Data for Human Active Site Mutant Enzyme Complexes
V. Cody, J. Pace, J. Makin, J. Piraino +2 more
2009Biochemistry27 citations Open access
Semantic Scholar
Structure determination of tetrahydroquinazoline antifolates in complex with human and Pneumocystis carinii dihydrofolate reductase: correlations between enzyme selectivity and stereochemistry.
V. Cody, J. Luft, W. Pangborn, A. Gangjee +1 more
2004Acta Crystallographica Section D: Biological Crystallography26 citations
Semantic Scholar
Design, synthesis, biological evaluation and X-ray crystal structure of novel classical 6,5,6-tricyclic benzo[4,5]thieno[2,3-d]pyrimidines as dual thymidylate synthase and dihydrofolate reductase inhibitors
Xin Zhang, Xilin Zhou, R. Kisliuk, J. Piraino +2 more
2011Bioorganic & Medicinal Chemistry25 citations Open access
Semantic Scholar
Structural analysis of Pneumocystis carinii and human DHFR complexes with NADPH and a series of five potent 6-[5'-(ω-carboxyalkoxy)benzyl]pyrido[2,3-d]pyrimidine derivatives.
V. Cody, J. Pace
2010Acta Crystallographica Section D: Biological Crystallography20 citations Open access
Semantic Scholar
Haloperidol: towards further understanding of the structural contributions of its pharmacophoric elements at D2-like receptors.
D. Sikazwe, Shou-Ming Li, Leroy G Mardenborough, V. Cody +2 more
2004Bioorganic & Medicinal Chemistry Letters20 citations Open access
Semantic Scholar
Kinetic and Structural Analysis for Potent Antifolate Inhibition of Pneumocystis jirovecii, Pneumocystis carinii, and Human Dihydrofolate Reductases and Their Active-Site Variants
V. Cody, J. Pace, S. Queener, O. Adair +1 more
2013Antimicrobial Agents and Chemotherapy18 citations Open access
Semantic Scholar
Probing the impact of the echinT C-terminal domain on structure and catalysis.
S. Bardaweel, J. Pace, T. Chou, V. Cody +1 more
2010Journal of Molecular Biology18 citations Open access
Semantic Scholar
Analysis of three crystal structure determinations of a 5-methyl-6-N-methylanilino pyridopyrimidine antifolate complex with human dihydrofolate reductase.
V. Cody, J. Luft, W. Pangborn, A. Gangjee
2003Acta Crystallographica Section D: Biological Crystallography17 citations
Semantic Scholar
Crystallographic Analysis Reveals a Novel Second Binding Site for Trimethoprim in Active Site Double Mutants of Human Dihydrofolate Reductase,
V. Cody, J. Pace, J. Piraino, S. Queener
2011Journal of Structural Biology16 citations Open access
Semantic Scholar
Structure-activity correlations for three pyrido[2,3-d]pyrimidine antifolates binding to human and Pneumocystis carinii dihydrofolate reductase.
V. Cody, J. Pace, Ojas A. Namjoshi, A. Gangjee
2015Acta Crystallographica Section F Structural Biology Communications15 citations Open access
Semantic Scholar
Ligand binding at the transthyretin dimer-dimer interface: structure of the transthyretin-T4Ac complex at 2.2 Angstrom resolution.
P. Neumann, V. Cody, A. Wojtczak
2005Acta Crystallographica Section D: Biological Crystallography15 citations
Semantic Scholar
Faculty Opinions recommendation of The crystal structure of transthyretin in complex with diethylstilbestrol: a promising template for the design of amyloid inhibitors.
V. Cody
200411 citations
Semantic Scholar
Structural characteristics of small-molecule antifolate compounds
C. Schwalbe, V. Cody
200610 citations
Semantic Scholar
Targeting Species Specific Amino Acid Residues: Design, Synthesis and Biological Evaluation of 6-Substituted Pyrrolo[2,3-d]pyrimidines as Dihydrofolate Reductase Inhibitors and Potential Anti-Opportunistic Infection Agents
Khushbu P. Shah, Xin Lin, S. Queener, V. Cody +2 more
2018Bioorganic & Medicinal Chemistry9 citations Open access
Semantic Scholar
Structure-activity correlations of variant forms of the B pentamer of Escherichia coli type II heat-labile enterotoxin LT-IIb with Toll-like receptor 2 binding.
V. Cody, J. Pace, H. Nawar, Natalie D. King-Lyons +3 more
2012Acta Crystallographica Section D: Biological Crystallography9 citations Open access
Semantic Scholar
Purification and characterization of human-derived Pneumocystis jirovecii dihydrofolate reductase expressed in Sf21 insect cells and in Escherichia coli.
V. Cody, Kim Chisum, C. Pope, S. Queener
2005Protein Expression and Purification9 citations
Semantic Scholar
Three-Dimensional Modeling of Thyroid Hormone Metabolites Binding to the Cancer-Relevant αvβ3 Integrin: In-Silico Based Study
D. Tobi, Eilon Krashin, P. Davis, V. Cody +2 more
2022Frontiers in Endocrinology6 citations Open access
Semantic Scholar
Design, Synthesis, Biological Evaluation And X-Ray Crystal Structure of Novel Classical 6,5,6-Tricyclic Benzo
Xin Zhang, Xilin Zhou, R. Kisliuk, J. Piraino +2 more
20136 citations
Semantic Scholar
Mechanisms of Molecular Recognition: Structural Characteristics of Transthyretin Ligand Interactions
V. Cody, A. Wojtczak
20096 citations
Semantic Scholar
Structural Analysis of the Complex of Human Transthyretin with 3′,5′-Dichlorophenylanthranilic Acid at 1.5 Å Resolution
V. Cody, J. Truong, Bruce Holdsworth, J. Holien +3 more
2022Molecules5 citations Open access
Semantic Scholar
Structural analysis of human dihydrofolate reductase as a binary complex with the potent and selective inhibitor 2,4-diamino-6-{2'-O-(3-carboxypropyl)oxydibenz[b,f]-azepin-5-yl}methylpteridine reveals an unusual binding mode.
V. Cody, J. Pace, J. Nowak
2011Acta Crystallographica Section D: Biological Crystallography5 citations Open access
Semantic Scholar
Preferential selection of isomer binding from chiral mixtures: alternate binding modes observed for the E and Z isomers of a series of 5-substituted 2,4-diaminofuro[2,3-d]pyrimidines as ternary complexes with NADPH and human dihydrofolate reductase.
V. Cody, J. Piraino, J. Pace, Wei Li +1 more
2010Acta Crystallographica Section D: Biological Crystallography4 citations Open access
Semantic Scholar
New Insights into DHFR Interactions: Analysis of Pneumocystis carinii and Mouse DHFR Complexes with NADPH and Two Highly Potent Trimethoprim Derivatives
V. Cody, J. Pace, Kim Chisum, A. Rosowsky
20064 citations
Semantic Scholar
Recombinant Bovine Dihydrofolate Reductase Produced by Mutagenesis and Nested PCR of Murine Dihydrofolate Reductase cDNA
V. Cody, Q. Mao, S. Queener
2008Protein Expression and Purification3 citations Open access
Semantic Scholar
Structure Determination of Tetrahydroquinazoline Antifolates in Complex with Human and Pneumocystis carinii Dihydrofolate Reductase: Correlations of Enzyme Selectivity and Stereochemistry
V. Cody, J. Luft, W. Pangborn, A. Gangjee +1 more
20043 citations
Semantic Scholar
human dihydrofolate reductase complex with NADPH and 5-methyl-6-(phenylthio-4'trifluoromethyl)thieno[2,3-d]pyrimidine-2,4-diamine
V. Cody, A. Ganjee
20172 citations
Semantic Scholar
Detection Enhancement of Protein Structural Vibrations: Measurements and Calculations
K. Niessen, Meng-Yang Xu, E. Snell, V. Cody +3 more
20152 citations
Semantic Scholar
Structural analysis of Pneumocystis carinii dihydrofolate reductase complexed with NADPH and 2,4-diamino-6-[2-(5-carboxypent-1-yn-1-yl)-5-methoxybenzyl]-5-methylpyrido[2,3-d]pyrimidine.
V. Cody, J. Pace, E. Stewart
2012Acta Crystallographica. Section F : Structural Biology and Crystallization Communications2 citations Open access
Semantic Scholar
Structural Analysis of Dihydrofolate Reductase and Thymidylate Synthase from Mammalian and Pathogenic Organisms
V. Cody
20122 citations
Semantic Scholar
Z-isomer of 2,4-Diaminofuro[2,3-d]pyrimidine Antifolate Promotes Unusual Crystal Packing in Human Dihydrofolate Reductase Ternary Complex
V. Cody, J. Pace, Lu Lin, A. Gangjee
2009Acta Crystallographica. Section F : Structural Biology and Crystallization Communications2 citations Open access
Semantic Scholar

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