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M. Blackman · SciRah

Researcher profile · Semantic Scholar

M. Blackman

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M. Blackman — researcher profile on SciRah

h-index: 13
Works: 21
Citations: 2,924

Most-cited papers

The Tetrazine Ligation: Fast Bioconjugation based on Inverse-electron-demand Diels-Alder Reactivity
M. Blackman, M. Royzen, J. Fox
2008Journal of the American Chemical Society1,402 citations Open access
Semantic Scholar
Genetic Encoding of Bicyclononynes and trans-Cyclooctenes for Site-Specific Protein Labeling in Vitro and in Live Mammalian Cells via Rapid Fluorogenic Diels–Alder Reactions
K. Lang, Lloyd S. Davis, Stephen Wallace, M. Mahesh +4 more
2012Journal of the American Chemical Society475 citations Open access
Semantic Scholar
Design and Synthesis of Highly Reactive Dienophiles for the Tetrazine-trans-Cyclooctene Ligation
M. T. Taylor, M. Blackman, O. Dmitrenko, J. Fox
2011Journal of the American Chemical Society308 citations Open access
Semantic Scholar
Genetically Encoded Tetrazine Amino Acid Directs Rapid Site-Specific In Vivo Bioorthogonal Ligation with trans-Cyclooctenes
Jason L Seitchik, Jennifer C. Peeler, M. T. Taylor, M. Blackman +5 more
2012Journal of the American Chemical Society233 citations Open access
Semantic Scholar
Tetrazine-trans-Cyclooctene Ligation for the Rapid Construction of 18F Labeled Probes
Zibo Li, Han-Cheng Cai, Matthew Hassink, M. Blackman +3 more
2010Chemical Communications176 citations Open access
Semantic Scholar
Discovery of Narlaprevir (SCH 900518): A Potent, Second Generation HCV NS3 Serine Protease Inhibitor.
A. Arasappan, F. Bennett, Stéphane L. Bogen, S. Venkatraman +33 more
2010ACS Medicinal Chemistry Letters87 citations Open access
Semantic Scholar
Peptide fragment coupling using a continuous-flow photochemical rearrangement of nitrones.
Y. Zhang, M. Blackman, Andrew B. Leduc, T. Jamison
2013Angewandte Chemie51 citations Open access
Semantic Scholar
Cyclic sulfones as novel P3-caps for hepatitis C virus NS3/4A (HCV NS3/4A) protease inhibitors: synthesis and evaluation of inhibitors with improved potency and pharmacokinetic profiles.
F. Velázquez, M. Sannigrahi, F. Bennett, R. Lovey +13 more
2010Journal of Medicinal Chemistry46 citations Open access
Semantic Scholar
Discovery and structure-activity relationship of P1-P3 ketoamide derived macrocyclic inhibitors of hepatitis C virus NS3 protease.
S. Venkatraman, F. Velázquez, Wanli Wu, M. Blackman +14 more
2009Journal of Medicinal Chemistry43 citations Open access
Semantic Scholar
Second-generation highly potent and selective inhibitors of the hepatitis C virus NS3 serine protease.
Kevin X. Chen, L. Nair, B. Vibulbhan, Weiying Yang +12 more
2009Journal of Medicinal Chemistry34 citations
Semantic Scholar
Application of ring-closing metathesis for the synthesis of macrocyclic peptidomimetics as inhibitors of HCV NS3 protease.
F. Velázquez, S. Venkatraman, Wanli Wu, M. Blackman +4 more
2007Organic Letters24 citations
Semantic Scholar
Potent ketoamide inhibitors of HCV NS3 protease derived from quaternized P1 groups.
S. Venkatraman, F. Velázquez, Wanli Wu, M. Blackman +2 more
2010Bioorganic & Medicinal Chemistry Letters18 citations
Semantic Scholar
Discovery of potent sulfonamide P4-capped ketoamide second generation inhibitors of hepatitis C virus NS3 serine protease with favorable pharmacokinetic profiles in preclinical species.
Stéphane L. Bogen, A. Arasappan, F. Velázquez, M. Blackman +9 more
2010Bioorganic & Medicinal Chemistry14 citations
Semantic Scholar
Design, synthesis, and evaluation of oxygen-containing macrocyclic peptidomimetics as inhibitors of HCV NS3 protease.
F. Velázquez, S. Venkatraman, M. Blackman, P. Pinto +8 more
2009Journal of Medicinal Chemistry13 citations Open access
Semantic Scholar
Tetrazine—trans‐cyclooctene Ligation for the Rapid Construction of 18F Labeled Probes.
Zibo Li, Han-Cheng Cai, Matthew Hassink, M. Blackman +3 more
20113 citations
Semantic Scholar
Tetrazine-trans-cyclooctene ligation (TTCO ligation) for the rapid construction of 18F labeled probes
Zibo Li, Ramajeyam Selvaraj, Chiun-Wei Huang, Matthew Hassink +4 more
20111 citations
Semantic Scholar
Peptide Fragment Coupling Using a Continuous‐Flow Photochemical Rearrangement of Nitrones.
Yuan Zhang, M. Blackman, Andrew B. Leduc, T. Jamison
20130 citations
Semantic Scholar
The tetrazine ligation: Development of a novel bioorthogonal Diels-Alder reaction and its applications
M. Blackman
20110 citations
Semantic Scholar
Bioorthogonal Ligation Using Site‐Specific Tetrazine‐Alkene Coupling On Proteins
Christian André Refakis, M. Blackman, J. Fox, R. Mehl
20100 citations
Semantic Scholar
HCV NS3 protease domain with P1-P3 macrocyclic ketoamide inhibitor
S. Venkatraman, F. Velázquez, W. Wu, M. Blackman +14 more
20100 citations
Semantic Scholar
Nouveaux composes en tant qu'inhibiteurs de la protease serine ns3 du virus de l'hepatite c
Ashok Arasappan, Frank C. Bennett, M. Blackman, Stephane L. Bogen +7 more
20050 citations
Semantic Scholar

Frequent co-authors

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S. Venkatraman×9
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S. Venkatraman — researcher profile on SciRah
F. Njoroge×9
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J. Fox×8
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F. Velázquez×8
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×7

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L. Nair — researcher profile on SciRah

Stéphane L. Bogen×6

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Neng-Yang Shih×6

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Kevin X. Chen×5

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