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E. Jacobson · SciRah

Researcher profile · Semantic Scholar

E. Jacobson

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E. Jacobson — researcher profile on SciRah

h-index: 48
Works: 161
Citations: 7,058

Most-cited papers

Cyclic ADP-ribose production by CD38 regulates intracellular calcium release, extracellular calcium influx and chemotaxis in neutrophils and is required for bacterial clearance in vivo
Santiago Partida-Sanchez, D. Cockayne, S. Monard, E. Jacobson +8 more
2001Nature Medicine484 citations
Semantic Scholar
Endogenous UVA-photosensitizers: mediators of skin photodamage and novel targets for skin photoprotection
G. Wondrak, M. Jacobson, E. Jacobson
2006Photochemical and Photobiological Sciences400 citations Open access
Semantic Scholar
Poly(ADP-ribose) Polymerase Null Mouse Cells Synthesize ADP-ribose Polymers*
W. Shieh, J. Amé, Mandala V. Wilson, Zhao-Qi Wang +3 more
1998Journal of Biological Chemistry327 citations Open access
Semantic Scholar
Human poly(ADP-ribose) glycohydrolase is expressed in alternative splice variants yielding isoforms that localize to different cell compartments.
M. Meyer-Ficca, R. Meyer, D. Coyle, E. Jacobson +1 more
2004Experimental Cell Research228 citations Open access
Semantic Scholar
Isolation and Characterization of the cDNA Encoding Bovine Poly(ADP-ribose) Glycohydrolase*
Wen-Sheng Lin, J. Amé, N. Aboul-ela, E. Jacobson +1 more
1997Journal of Biological Chemistry224 citations Open access
Semantic Scholar
Depletion of the 110-Kilodalton Isoform of Poly(ADP-Ribose) Glycohydrolase Increases Sensitivity to Genotoxic and Endotoxic Stress in Mice
U. Cortes, Wei-Min Tong, D. Coyle, M. Meyer-Ficca +6 more
2004Molecular and Cellular Biology186 citations Open access
Semantic Scholar
Inhibition of advanced glycation end product formation on collagen by rutin and its metabolites.
D. Cervantes-Laurean, Derek D. Schramm, E. Jacobson, I. Halaweish +2 more
2006Journal of Nutritional Biochemistry159 citations
Semantic Scholar
Glycation and Glycoxidation of Histones by ADP-ribose (*)
D. Cervantes-Laurean, E. Jacobson, M. Jacobson
1996Journal of Biological Chemistry129 citations Open access
Semantic Scholar
DNA damage by carbonyl stress in human skin cells.
M. J. Roberts, G. Wondrak, Daniel Cervantes Laurean, M. Jacobson +1 more
2003Mutation research125 citations
Semantic Scholar
Proteins of the extracellular matrix are sensitizers of photo-oxidative stress in human skin cells.
G. Wondrak, M. J. Roberts, D. Cervantes-Laurean, M. Jacobson +1 more
2003Journal of Investigative Dermatology115 citations Open access
Semantic Scholar
Poly(ADP-ribose) polymerases: managing genome stability.
M. Meyer-Ficca, R. Meyer, E. Jacobson, M. Jacobson
2005International Journal of Biochemistry and Cell Biology104 citations
Semantic Scholar
Discovering new ADP-ribose polymer cycles: protecting the genome and more.
M. Jacobson, E. Jacobson
1999TIBS -Trends in Biochemical Sciences. Regular ed101 citations
Semantic Scholar
Identification of α-dicarbonyl scavengers for cellular protection against carbonyl stress
G. Wondrak, D. Cervantes-Laurean, M. J. Roberts, Jaber G. Qasem +3 more
200296 citations
Semantic Scholar
Mapping the role of NAD metabolism in prevention and treatment of carcinogenesis.
E. Jacobson, W. Shieh, Arnold C. Huang
199994 citations
Semantic Scholar
Two small enzyme isoforms mediate mammalian mitochondrial poly(ADP-ribose) glycohydrolase (PARG) activity.
R. Meyer, M. Meyer-Ficca, Clifford J. Whatcott, E. Jacobson +1 more
2007Experimental Cell Research90 citations Open access
Semantic Scholar
Histone carbonylation in vivo and in vitro.
G. Wondrak, D. Cervantes-Laurean, E. Jacobson, M. Jacobson
2000Biochemical Journal90 citations Open access
Semantic Scholar
Photosensitized growth inhibition of cultured human skin cells: mechanism and suppression of oxidative stress from solar irradiation of glycated proteins.
G. Wondrak, M. J. Roberts, M. Jacobson, E. Jacobson
2002Journal of Investigative Dermatology76 citations Open access
Semantic Scholar
3-Hydroxypyridine Chromophores Are Endogenous Sensitizers of Photooxidative Stress in Human Skin Cells*
G. Wondrak, M. J. Roberts, M. Jacobson, E. Jacobson
2004Journal of Biological Chemistry75 citations Open access
Semantic Scholar
Human poly(ADP-ribose) glycohydrolase (PARG) gene and the common promoter sequence it shares with inner mitochondrial membrane translocase 23 (TIM23).
R. Meyer, M. Meyer-Ficca, E. Jacobson, M. Jacobson
2003Gene73 citations
Semantic Scholar
Optimizing the energy status of skin cells during solar radiation.
E. Jacobson, Paolo U. Giacomoni, Michael J. Roberts, G. Wondrak +1 more
2001Journal of Photochemistry and Photobiology. B: Biology69 citations
Semantic Scholar
Altered poly(ADP-ribose) metabolism impairs cellular responses to genotoxic stress in a hypomorphic mutant of poly(ADP-ribose) glycohydrolase.
Hong Gao, D. Coyle, M. Meyer-Ficca, R. Meyer +3 more
2007Experimental Cell Research68 citations
Semantic Scholar
Effects of Niacin Restriction on Sirtuin and PARP Responses to Photodamage in Human Skin
Claudia A. Benavente, Stephanie A. Schnell, E. Jacobson
2012PLoS ONE67 citations Open access
Semantic Scholar
Niacin restriction upregulates NADPH oxidase and reactive oxygen species (ROS) in human keratinocytes.
Claudia A. Benavente, E. Jacobson
2008Free Radical Biology & Medicine66 citations Open access
Semantic Scholar
A topical lipophilic niacin derivative increases NAD, epidermal differentiation and barrier function in photodamaged skin
E. Jacobson, Hyuntae Kim, Moonsun Kim, Joshua D. Williams +6 more
2007Experimental Dermatology61 citations
Semantic Scholar
NAD in skin: therapeutic approaches for niacin.
Claudia A. Benavente, M. Jacobson, E. Jacobson
2009Current pharmaceutical design56 citations
Semantic Scholar
Identification of Quenchers of Photoexcited States as Novel Agents for Skin Photoprotection
G. Wondrak, M. Jacobson, E. Jacobson
2005Journal of Pharmacology and Experimental Therapeutics55 citations
Semantic Scholar
Nuclear proteasome activation and degradation of carboxymethylated histones in human keratinocytes following glyoxal treatment.
D. Cervantes-Laurean, M. J. Roberts, E. Jacobson, M. Jacobson
2005Free Radical Biology & Medicine44 citations
Semantic Scholar
Folate in Skin Cancer Prevention
Joshua D. Williams, E. Jacobson, Hyuntae Kim, Moonsun Kim +1 more
2012Sub-cellular biochemistry40 citations Open access
Semantic Scholar
ADP-ribose in glycation and glycoxidation reactions.
E. Jacobson, Daniel Cervantes-Laurean, M. Jacobson
1997Advances in Experimental Medicine and Biology40 citations
Semantic Scholar
UVA is the major contributor to the photodegradation of tretinoin and isotretinoin: Implications for development of improved pharmaceutical formulations.
B. Tashtoush, E. Jacobson, M. Jacobson
2008International journal of pharmaceutics39 citations Open access
Semantic Scholar
A rapid HPLC method for simultaneous determination of tretinoin and isotretinoin in dermatological formulations.
B. Tashtoush, E. Jacobson, M. Jacobson
2007Journal of Pharmaceutical and Biomedical Analysis39 citations
Semantic Scholar
Simultaneous determination of myristyl nicotinate, nicotinic acid, and nicotinamide in rabbit plasma by liquid chromatography-tandem mass spectrometry using methyl ethyl ketone as a deproteinization solvent.
P. Catz, Walter M Shinn, I. Kapetanovic, Hyuntae Kim +4 more
2005Journal of chromatography. B, Analytical technologies in the biomedical and life sciences39 citations
Semantic Scholar
Identification of alpha-dicarbonyl scavengers for cellular protection against carbonyl stress.
G. Wondrak, D. Cervantes-Laurean, M. J. Roberts, Jaber G. Qasem +3 more
2002Biochemical Pharmacology36 citations
Semantic Scholar
Vitamin B6: beyond coenzyme functions.
G. Wondrak, E. Jacobson
2012Sub-cellular biochemistry35 citations
Semantic Scholar
Validation of a Simple and Rapid HPLC Method for Determination of Metronidazole in Dermatological Formulations
B. Tashtoush, E. Jacobson, M. Jacobson
2008Drug Development and Industrial Pharmacy34 citations
Semantic Scholar
Molecular heterogeneity and regulation of poly(ADP-ribose) glycohydrolase
J. Amé, E. Jacobson, M. Jacobson
1999Molecular and Cellular Biochemistry34 citations
Semantic Scholar
Patchy field defects of apoptosis resistance and dedifferentiation in flat mucosa of colon resections from colon cancer patients
H. Bernstein, H. Holubec, J. Warneke, H. Garewal +6 more
2002Annals of Surgical Oncology33 citations
Semantic Scholar
Assignment1 of the poly(ADP-ribose) glycohydrolase gene (PARG) to human chromosome 10q11.23 and mouse chromosome 14B by in situ hybridization
J. Amé, F. Apiou, E. Jacobson, M. Jacobson
1999Cytogenetic and Genome Research32 citations
Semantic Scholar
Photosensitization of DNA damage by glycated proteins
G. Wondrak, E. Jacobson, M. Jacobson
2002Photochemical and Photobiological Sciences31 citations Open access
Semantic Scholar
Vitamin B3 in Health and Disease: Toward the Second Century of Discovery.
M. Jacobson, E. Jacobson
2018Methods in molecular biology30 citations
Semantic Scholar
A pilot study evaluating the efficacy of topically applied niacin derivatives for treatment of female pattern alopecia
Z. Draelos, E. Jacobson, Hyuntae Kim, Moonsun Kim +1 more
2005Journal of Cosmetic Dermatology30 citations
Semantic Scholar
Lymphoma cells with increased anti-oxidant defenses acquire chemoresistance
M. Tome, J. Frye, D. Coyle, E. Jacobson +4 more
2012Experimental and Therapeutic Medicine29 citations Open access
Semantic Scholar
Nicotinic Acid Receptor Abnormalities in Human Skin Cancer: Implications for a Role in Epidermal Differentiation
Yira Bermudez, Claudia A. Benavente, R. Meyer, W. R. Coyle +2 more
2011PLoS ONE28 citations Open access
Semantic Scholar
Antimelanoma Activity of Apoptogenic Carbonyl Scavengers
G. Wondrak, M. Jacobson, E. Jacobson
2006Journal of Pharmacology and Experimental Therapeutics28 citations
Semantic Scholar
Preparation of low molecular weight model conjugates for ADP-ribose linkages to protein.
D. Cervantes-Laurean, E. Jacobson, M. Jacobson
1997Methods in Enzymology25 citations
Semantic Scholar
Water maze performance in young male Long-Evans rats is inversely affected by dietary intakes of niacin and may be linked to levels of the NAD+ metabolite cADPR.
G. Young, E. Jacobson, J. Kirkland
2007Journal of NutriLife23 citations Open access
Semantic Scholar
Niacin: vitamin and antidyslipidemic drug.
E. Jacobson, Hyuntae Kim, Moonsun Kim, M. Jacobson
2012Sub-cellular biochemistry22 citations
Semantic Scholar
Enzymes in Poly(ADP-Ribose) Metabolism
R. Meyer, M. Meyer-Ficca, E. Jacobson, M. Jacobson
200620 citations
Semantic Scholar
Modulation of VP-16 cytotoxicity by carboplatin and 41.8°C hyperthermia
D. Katschinski, E. Jacobson, G. Wiedemann, H. Robins
2001Journal of Cancer Research and Clinical Oncology19 citations Open access
Semantic Scholar
Effect of myristyl nicotinate on retinoic acid therapy for facial photodamage
M. Jacobson, Hyuntae Kim, W. R. Coyle, Moonsun Kim +3 more
2007Experimental Dermatology14 citations
Semantic Scholar

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