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J. Frye · SciRah

Researcher profile · Semantic Scholar

J. Frye

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J. Frye — researcher profile on SciRah

h-index: 21
Works: 52
Citations: 1,622

Most-cited papers

Turmeric extracts containing curcuminoids prevent experimental rheumatoid arthritis.
J. Funk, J. Oyarzo, J. Frye, Guan-Jie Chen +4 more
2006Journal of Natural Products233 citations Open access
Semantic Scholar
Efficacy and mechanism of action of turmeric supplements in the treatment of experimental arthritis.
Janet L. Funk, J. Frye, J. Oyarzo, N. Kuscuoglu +9 more
2006Arthritis & Rheumatism143 citations
Semantic Scholar
Bioactivity of Turmeric-Derived Curcuminoids and Related Metabolites in Breast Cancer
Laura E. Wright, J. Frye, Bhavana Gorti, B. Timmermann +1 more
2013Current pharmaceutical design138 citations Open access
Semantic Scholar
Anti-Inflammatory Effects of the Essential Oils of Ginger (Zingiber officinale Roscoe) in Experimental Rheumatoid Arthritis
J. Funk, J. Frye, J. Oyarzo, Jian-Ling Chen +2 more
2016PharmaNutrition135 citations Open access
Semantic Scholar
Comparative Effects of Two Gingerol-Containing Zingiber officinale Extracts on Experimental Rheumatoid Arthritis
J. Funk, J. Frye, J. Oyarzo, B. Timmermann
2009Journal of Natural Products125 citations Open access
Semantic Scholar
Anti-Arthritic Effects and Toxicity of the Essential Oils of Turmeric (Curcuma longa L.)
J. Funk, J. Frye, J. Oyarzo, Hua-Ping Zhang +1 more
2010Journal of Agricultural and Food Chemistry120 citations Open access
Semantic Scholar
Increased manganese superoxide dismutase expression or treatment with a manganese porphyrin potentiates dexamethasone-induced apoptosis in lymphoma cells
Melba C. Jaramillo, J. Frye, J. Crapo, M. Briehl +1 more
2009Cancer Research75 citations Open access
Semantic Scholar
Multiplex immunoassay characterization and species comparison of inflammation in acute and non-acute ischemic infarcts in human and mouse brain tissue
Thuy-vi Nguyen, J. Frye, Jacob C. Zbesko, Kristina Stepanović +5 more
2016Acta Neuropathologica Communications67 citations Open access
Semantic Scholar
Curcumin, but not curcumin-glucuronide, inhibits Smad-signaling in TGFβ-dependent bone metastatic breast cancer cells and is enriched in bone compared to other tissues
Andrew G. Kunihiro, Julia A Brickey, J. Frye, P. B. Luis +2 more
2018Journal of Nutritional Biochemistry50 citations Open access
Semantic Scholar
Exaggerated Neutrophil-Mediated Reperfusion Injury after Ischemic Stroke in a Rodent Model of Type 2 Diabetes
L. Ritter, Lisa B. Davidson, Melissa Henry, G. Davis-Gorman +6 more
2011Microcirculation48 citations Open access
Semantic Scholar
Curcuminoids Block TGF-β Signaling in Human Breast Cancer Cells and Limit Osteolysis in a Murine Model of Breast Cancer Bone Metastasis
Laura E. Wright, J. Frye, A. Lukefahr, B. Timmermann +3 more
2012Journal of Natural Products47 citations Open access
Semantic Scholar
Beta-glucuronidase catalyzes deconjugation and activation of curcumin-glucuronide in bone
Andrew G. Kunihiro, P. B. Luis, Julia A Brickey, J. Frye +3 more
2019Journal of Natural Products45 citations Open access
Semantic Scholar
The Contribution of Mannose Binding Lectin to Reperfusion Injury after Ischemic Stroke
Helena W. Morrison, J. Frye, G. Davis-Gorman, J. Funk +3 more
2011Current Neurovascular Research36 citations Open access
Semantic Scholar
Protection of Trabecular Bone in Ovariectomized Rats by Turmeric (Curcuma longa L.) is Dependent on Extract Composition
Laura E. Wright, J. Frye, B. Timmermann, J. Funk
2010Journal of Agricultural and Food Chemistry35 citations Open access
Semantic Scholar
Repeated Administration of 2-Hydroxypropyl-β-Cyclodextrin (HPβCD) Attenuates the Chronic Inflammatory Response to Experimental Stroke
D. Becktel, Jacob C. Zbesko, J. Frye, Amanda G. Chung +10 more
2021Journal of Neuroscience33 citations Open access
Semantic Scholar
Alzheimer’s associated amyloid and tau deposition co-localizes with a homeostatic myelin repair pathway in two mouse models of post-stroke mixed dementia
Thuy-vi Nguyen, M. Hayes, Jacob C. Zbesko, J. Frye +5 more
2018Acta Neuropathologica Communications33 citations Open access
Semantic Scholar
Curcuminoids Limit Neutrophil-Mediated Reperfusion Injury in Experimental Stroke by Targeting the Endothelium
Janet L. Funk, J. Frye, G. Davis-Gorman, Allison L. Spera +6 more
2013Microcirculation32 citations Open access
Semantic Scholar
Decreased Bone Mineral Density in Rats Rendered Follicle-Deplete by an Ovotoxic Chemical Correlates with Changes in Follicle-Stimulating Hormone and Inhibin A
A. Lukefahr, J. Frye, Laura E. Wright, Samuel L. Marion +2 more
2012Calcified Tissue International32 citations Open access
Semantic Scholar
Lymphoma cells with increased anti-oxidant defenses acquire chemoresistance
M. Tome, J. Frye, D. Coyle, E. Jacobson +4 more
2012Experimental and Therapeutic Medicine29 citations Open access
Semantic Scholar
Modeling perimenopause in Sprague-Dawley rats by chemical manipulation of the transition to ovarian failure.
J. Frye, A. Lukefahr, Laura E. Wright, Samuel L. Marion +2 more
2012Comparative medicine27 citations
Semantic Scholar
IgA natural antibodies are produced following T-cell independent B-cell activation following stroke
Jacob C. Zbesko, J. Frye, D. Becktel, Diana K. Gerardo +5 more
2020Brain, behavior, and immunity26 citations Open access
Semantic Scholar
Bone-specific metabolism of dietary polyphenols in resorptive bone diseases
Andrew G. Kunihiro, P. B. Luis, J. Frye, Wade M. Chew +3 more
2020Molecular Nutrition & Food Research18 citations Open access
Semantic Scholar
Post-Stroke Administration of the p75 Neurotrophin Receptor Modulator, LM11A-31, Attenuates Chronic Changes in Brain Metabolism, Increases Neurotransmitter Levels, and Improves Recovery
Thuy-vi Nguyen, R. Crumpacker, Kylie Calderon, Frankie G. Garcia +10 more
2021Journal of Pharmacology and Experimental Therapeutics13 citations Open access
Semantic Scholar
Curcumin Inhibition of TGFβ signaling in bone metastatic breast cancer cells and the possible role of oxidative metabolites
Andrew G. Kunihiro, Julia A Brickey, J. Frye, Julia N. Cheng +3 more
2021Journal of Nutritional Biochemistry13 citations Open access
Semantic Scholar
4-Vinylcyclohexene Diepoxide (VCD) Inhibits Mammary Epithelial Differentiation and Induces Fibroadenoma Formation in Female Sprague Dawley Rats
Laura E. Wright, J. Frye, A. Lukefahr, Samuel L. Marion +3 more
2011Reproductive Toxicology11 citations Open access
Semantic Scholar
A Role for TGFβ Signaling in Preclinical Osteolytic Estrogen Receptor-Positive Breast Cancer Bone Metastases Progression
Julia N. Cheng, J. Frye, Susan A. Whitman, Andrew G. Kunihiro +2 more
2021International Journal of Molecular Sciences10 citations Open access
Semantic Scholar
Effects of Ginger (Zingiber officialis L) on Inflammation‐Induced Bone Loss
Janet L. Funk, J. Frye, Laura E. Wright, B. Timmermann
201210 citations
Semantic Scholar
Association of ß-glucuronidase activity with menopausal status, ethnicity, adiposity and inflammation in women
J. Funk, B. Wertheim, J. Frye, R. Blew +3 more
2023Menopause9 citations
Semantic Scholar
Osteolytic effects of tumoral estrogen signaling in an estrogen receptor-positive breast cancer bone metastasis model
Julia N. Cheng, J. Frye, Susan A. Whitman, Andrew G. Kunihiro +2 more
2021Journal of Cancer Metastasis and Treatment6 citations Open access
Semantic Scholar
Skeletal impact of 17β-estradiol in T cell-deficient mice: age-dependent bone effects and osteosarcoma formation
Julia N. Cheng, J. Frye, Susan A. Whitman, J. Funk
2019Clinical and Experimental Metastasis6 citations Open access
Semantic Scholar
Interrogating Estrogen Signaling Pathways in Human ER-Positive Breast Cancer Cells Forming Bone Metastases in Mice.
Julia N. Cheng, J. Frye, Susan A. Whitman, S. Ehsani +2 more
2024Endocrinology4 citations Open access
Semantic Scholar
Comparative Effects of Turmeric Secondary Metabolites Across Resorptive Bone Diseases
L. E. Wright, J. Frye, Andrew G. Kunihiro, B. Timmermann +1 more
2025Metabolites3 citations Open access
Semantic Scholar
Development of a Novel Mouse Model of Menopause-associated Asthma.
W. Pederson, L. Ellerman, Estevan Sandoval, S. Boitano +5 more
2022American Journal of Respiratory Cell and Molecular Biology3 citations Open access
Semantic Scholar
Erratum to: Multiplex immunoassay characterization and species comparison of inflammation in acute and non-acute ischemic infarcts in human and mouse brain tissue
Thuy-vi Nguyen, J. Frye, Jacob C. Zbesko, Kristina Stepanović +5 more
2016Acta Neuropathologica Communications3 citations Open access
Semantic Scholar
P01.55. Turmeric inhibits parathyroid hormone-related protein (PTHrP) secretion from human rheumatoid synoviocytes
J. Frye, B. Timmermann, Janet L. Funk
2012BMC Complementary and Alternative Medicine3 citations Open access
Semantic Scholar
Unraveling the role of estrogen signaling in the breast cancer-bone connection
J. Funk, J. Frye, Susan A. Whitman, Albiya Thomas +3 more
2023Physiology2 citations
Semantic Scholar
Medicinal Zingiberaceae in the prevention of menopausal bone loss
Laura E. Wright, J. Frye, B. Timmermann, J. Funk
20082 citations
Semantic Scholar
Abstract 4207: Zoledronic acid reduces quiescent bone-disseminated human ER+ breast cancer tumor cell burden and estrogen-responsiveness in a pre-clinical model
Julia N. Cheng, J. Frye, Susan A. Whitman, Janet L. Funk
2024Cancer Research1 citations
Semantic Scholar
Abstract 2685: Targeting TGFβ signaling pathways in bone metastatic breast cancer cells to limit metastatic progression using curcuminoids, a turmeric-derived natural product
Andrew G. Kunihiro, Julia A Brickey, J. Frye, J. Funk
2018Cancer Chemistry1 citations
Semantic Scholar
3015-LB: Genetic Variation in GUSB Is Associated with Circulating ß-Glucuronidase and Metabolic Traits in Hispanic Postmenopausal Women
Dawn K. Coletta, N. Fatima, Susan A. Whitman, J. Frye +3 more
2026Diabetes0 citations
Semantic Scholar
Interrogating Steroid Hormone Signaling in a Murine Model of ER+ Human Breast Cancer Bone Metastases
Amanda L Babcock, S. Ehsani, J. N. Farr, J. Frye +3 more
2025Endocrinology0 citations
Semantic Scholar
SAT-311 Investigating the Effects of Non-Estrogenic Reproductive Hormones on Human Estrogen Receptor-Positive Breast Cancer Bone Metastases in a Murine Model
Amanda L Babcock, J. Frye, Susan A. Whitman, A. M. Rossi +3 more
2025Journal of the Endocrine Society0 citations Open access
Semantic Scholar
Abbreviated Title ( 50-character maximum ) : HPβCD attenuates chronic inflammation 4 after stroke 5 6
D. Becktel, Jacob C. Zbesko, J. Frye, Amanda G. Chung +11 more
20210 citations
Semantic Scholar
Abstract 3002: Bone-protective curcumin circulates as a pro-drug conjugate that is activated in bone by β-glucuronidase
Andrew G. Kunihiro, Julia A Brickey, J. Frye, P. B. Luis +2 more
2019Experimental and Molecular Therapeutics0 citations
Semantic Scholar
Abstract 2042: Modeling estrogen receptor-positive breast cancer bone metastasis to query osteolytic effects of tumor ER signaling
Julia N. Cheng, J. Frye, Susan A. Whitman, Andrew G. Kunihiro +4 more
2019Tumor Biology0 citations Open access
Semantic Scholar
Abstract 2116: Tumor-specific effects of estrogen drive a murine model of human estrogen receptor-positive breast cancer bone metastasis independent of bone microenvironment changes
Julia N. Cheng, J. Frye, Susan A. Whitman, Andrew G. Kunihiro +3 more
2018Tumor Biology0 citations
Semantic Scholar
Abstract P6-18-01: Site-specific activation of curcuminoids in the breast cancer bone metastases microenvironment
Andrew G. Kunihiro, J. Frye, Julia A Brickey, P. B. Luis +2 more
20170 citations
Semantic Scholar
Abstract P4-06-08: Characterization of an estrogen-dependent murine model of human estrogen receptor-positive breast cancer bone metastasis
Julia N. Cheng, J. Frye, Susan A. Whitman, Andrew G. Kunihiro +1 more
20170 citations
Semantic Scholar
Characterizing Bone Tropism of Human ER+ Breast Cancer Cell Lines in a Murine Bone Metastasis Model
Julia N. Cheng, J. Frye, Susan A. Whitman, Janet L. Funk
2016The FASEB Journal0 citations Open access
Semantic Scholar
Site‐Specific Deglucuronidation of Turmeric‐Derived Curcuminoids in Bone
Andrew G. Kunihiro, J. Frye, P. B. Luis, C. Schneider +1 more
2016The FASEB Journal0 citations Open access
Semantic Scholar

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