J. Lorenz

Most-cited papers

Extracellular Signal-Regulated Kinases 1 and 2 Regulate the Balance Between Eccentric and Concentric Cardiac Growth
I. Kehat, Jennifer Davis, M. Tiburcy, F. Accornero +7 more
2011Circulation Research267 citations Open access
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Cardiac myosin binding protein c phosphorylation is cardioprotective
S. Sadayappan, H. Osińska, R. Klevitsky, J. Lorenz +5 more
2006Proceedings of the National Academy of Sciences of the United States of America227 citations Open access
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Inhibiting fibronectin attenuates fibrosis and improves cardiac function in a model of heart failure
Íñigo Valiente-Alandí, Sarah J. Potter, Ane M. Salvador, A. Schafer +12 more
2018Circulation221 citations Open access
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A thrombospondin-dependent pathway for a protective ER stress response
J. Lynch, Marjorie Maillet, D. Vanhoutte, A. Schloemer +12 more
2012Cell213 citations Open access
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Peripheral Nociception Associated With Surgical Incision Elicits Remote Nonischemic Cardioprotection Via Neurogenic Activation of Protein Kinase C Signaling
W. Jones, G. Fan, Siyun Liao, Jun-Ming Zhang +6 more
2009Circulation170 citations Open access
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Nix-Mediated Apoptosis Links Myocardial Fibrosis, Cardiac Remodeling, and Hypertrophy Decompensation
A. Diwan, J. Wansapura, Faisal M. Syed, S. Matkovich +2 more
2008Circulation163 citations Open access
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Colonic anion secretory defects and metabolic acidosis in mice lacking the NBC1 Na+/HCO3- cotransporter.
Lara R. Gawenis, Emily M. Bradford, V. Prasad, J. Lorenz +8 more
2007Journal of Biological Chemistry148 citations Open access
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A Critical Function for Ser-282 in Cardiac Myosin Binding Protein-C Phosphorylation and Cardiac Function
S. Sadayappan, J. Gulick, H. Osińska, David Y. Barefield +11 more
2011Circulation Research140 citations Open access
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Interaction between transcellular and paracellular water transport pathways through Aquaporin 5 and the tight junction complex
J. Kawedia, M. Nieman, G. Boivin, J. Melvin +4 more
2007Proceedings of the National Academy of Sciences of the United States of America127 citations Open access
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Cardiac Myosin Binding Protein-C Phosphorylation in a “Humanized” Mouse Heart
S. Sadayappan, J. Gulick, R. Klevitsky, J. Lorenz +3 more
2009Circulation113 citations Open access
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Vascular dysfunction in S1P2 sphingosine 1-phosphate receptor knockout mice.
J. Lorenz, L. Arend, R. Robitz, Richard J. Paul +1 more
2007American Journal of Physiology. Regulatory Integrative and Comparative Physiology110 citations
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Unrestrained p38 MAPK Activation in Dusp1/4 Double Null Mice Induces Cardiomyopathy
M. Auger-Messier, F. Accornero, Sanjeewa A. Goonasekera, O. Bueno +4 more
2012Circulation Research97 citations Open access
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alpha1G-dependent T-type Ca2+ current antagonizes cardiac hypertrophy through a NOS3-dependent mechanism in mice.
Hiroyuki Nakayama, I. Bódi, Robert N. Correll, Xiong-Wen Chen +5 more
2009Journal of Clinical Investigation95 citations Open access
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Autonomic dysfunction following traumatic brain injury: translational insights.
F. Khalid, George L. Yang, J. McGuire, M. Robson +3 more
2019Neurosurgical Focus86 citations Open access
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Probenecid: novel use as a non-injurious positive inotrope acting via cardiac TRPV2 stimulation
Sheryl E. Koch, Xiaoqian Gao, Lauren L Haar, Min Jiang +12 more
2012Journal of Molecular and Cellular Cardiology82 citations Open access
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Ouabain-Sensitive alpha1 Na,K-ATPase enhances natriuretic response to saline load.
Elizabeth L. Loreaux, B. Kaul, J. Lorenz, J. Lingrel
2008Journal of the American Society of Nephrology74 citations Open access
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Sickle cell anemia mice develop a unique cardiomyopathy with restrictive physiology
N. Bakeer, Jeanne M. James, Swarnava Roy, J. Wansapura +14 more
2016Proceedings of the National Academy of Sciences of the United States of America72 citations Open access
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Cardiac Dysfunction in the Sigma 1 Receptor Knockout Mouse Associated With Impaired Mitochondrial Dynamics and Bioenergetics
C. S. Abdullah, S. Alam, Richa Aishwarya, S. Miriyala +9 more
2018Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease71 citations Open access
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Novel role of transient receptor potential vanilloid 2 in the regulation of cardiac performance.
Jack Rubinstein, V. Lasko, Sheryl E. Koch, V. Singh +8 more
2014American Journal of Physiology. Heart and Circulatory Physiology70 citations Open access
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ACTH-induced hypertension is dependent on the ouabain-binding site of the alpha2-Na+-K+-ATPase subunit.
J. Lorenz, Elizabeth L. Loreaux, Iva Dostanic-Larson, V. Lasko +3 more
2008American Journal of Physiology. Heart and Circulatory Physiology70 citations Open access
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Pharmacological and Activated Fibroblast Targeting of Gβγ-GRK2 After Myocardial Ischemia Attenuates Heart Failure Progression
Joshua G. Travers, Fadia Kamal, Íñigo Valiente-Alandí, M. Nieman +4 more
2017Journal of the American College of Cardiology63 citations Open access
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Inducible and myocyte-specific inhibition of PKCalpha enhances cardiac contractility and protects against infarction-induced heart failure.
Michael A. Hambleton, Allen J. York, Michelle A. Sargent, R. A. Kaiser +3 more
2007American Journal of Physiology. Heart and Circulatory Physiology57 citations Open access
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Biochemical and Mechanical Dysfunction in a Mouse Model of Desmin-Related Myopathy
A. Maloyan, H. Osińska, J. Lammerding, Richard T. Lee +4 more
2009Circulation Research52 citations Open access
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Mice expressing ouabain‐sensitive α1 Na,K‐ATPase have increased susceptibility to pressure overload‐induced cardiac hypertrophy
Arshani N. Wansapura, V. Lasko, J. Lingrel, J. Lorenz
2009American Journal of Physiology. Heart and Circulatory Physiology51 citations Open access
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Heart-specific Deletion of CnB1 Reveals Multiple Mechanisms Whereby Calcineurin Regulates Cardiac Growth and Function
Marjorie Maillet, Jennifer Davis, M. Auger-Messier, Allen J. York +6 more
2009Journal of Biological Chemistry48 citations Open access
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Fast skeletal myosin-binding protein-C regulates fast skeletal muscle contraction
Taejeong Song, James W. McNamara, Weikang Ma, Maicon Landim-Vieira +8 more
2021Proceedings of the National Academy of Sciences of the United States of America45 citations Open access
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Overexpression of miR-223 Tips the Balance of Pro- and Anti-hypertrophic Signaling Cascades toward Physiologic Cardiac Hypertrophy*
Li-Wang Yang, Yutian Li, Xiao-Hong Wang, Xingjiang Mu +12 more
2016Journal of Biological Chemistry43 citations Open access
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Loss of NHE1 activity leads to reduced oxidative stress in heart and mitigates high-fat diet-induced myocardial stress
V. Prasad, J. Lorenz, Marian L. Miller, Kanimozhi Vairamani +3 more
2013Journal of Molecular and Cellular Cardiology42 citations Open access
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Transgenic mice expressing Na+-K+-ATPase in smooth muscle decreases blood pressure.
Tracy J. Pritchard, Michelle S. Parvatiyar, Daniel P. Bullard, R. Lynch +2 more
2007American Journal of Physiology. Heart and Circulatory Physiology42 citations
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Chymase: the other ACE?
J. Lorenz
2010AJP - Renal Physiology41 citations Open access
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Increased renal renin content in mice lacking the Na+/H+ exchanger NHE2.
Fiona Hanner, R. Chambrey, S. Bourgeois, Elliott J. Meer +6 more
2008AJP - Renal Physiology35 citations Open access
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Marinobufagenin enhances cardiac contractility in mice with ouabain-sensitive alpha1 Na+-K+-ATPase.
A. Wansapura, V. Lasko, Zi-Jian Xie, O. Fedorova +3 more
2008American Journal of Physiology. Heart and Circulatory Physiology35 citations Open access
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Role of the acidic N′ region of cardiac troponin I in regulating myocardial function
S. Sadayappan, N. Finley, Jack W. Howarth, H. Osińska +4 more
2008The FASEB Journal34 citations Open access
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Expression of Active Protein Phosphatase 1 Inhibitor-1 Attenuates Chronic Beta-Agonist-Induced Cardiac Apoptosis
Guoli Chen, Xiao-Yang Zhou, Stela M. Florea, Jiang Qian +6 more
2010Basic Research in Cardiology33 citations Open access
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Transient receptor potential vanilloid 2 function regulates cardiac hypertrophy via stretch-induced activation
Sheryl E. Koch, Adrien Mann, Shannon M. Jones, Nathan Robbins +10 more
2017Journal of Hypertension32 citations
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Impaired Cardiac Contractility in Mice Lacking Both the AE3 \batchmode \documentclass[fleqn,10pt,legalpaper]{article} \usepackage{amssymb} \usepackage{amsfonts} \usepackage{amsmath} \pagestyle{empty} \begin{document} \(\mathrm{Cl}^{-}{/}\mathrm{HCO}_{3}^{-}\) \end{document} Exchanger and the NKCC1 N
V. Prasad, I. Bódi, Jamie W. Meyer, Yi-Gang Wang +8 more
2008Journal of Biological Chemistry32 citations Open access
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Abnormal Calcium Cycling and Cardiac Arrhythmias Associated With the Human Ser96Ala Genetic Variant of Histidine‐Rich Calcium‐Binding Protein
V. Singh, Jack Rubinstein, D. Arvanitis, Xiao-Ping Ren +12 more
2013Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease29 citations Open access
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Loss of the AE3 Anion Exchanger in a Hypertrophic Cardiomyopathy Model Causes Rapid Decompensation and Heart Failure
Nabeel J. Al Moamen, V. Prasad, I. Bódi, Marian L. Miller +6 more
2010Journal of Molecular and Cellular Cardiology29 citations Open access
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Constitutive phosphorylation of inhibitor-1 at Ser67 and Thr75 depresses calcium cycling in cardiomyocytes and leads to remodeling upon aging
Stela M. Florea, Ahmad Anjak, Wen-Feng Cai, Jiang Qian +6 more
2012Basic Research in Cardiology28 citations Open access
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Renovascular hypertension using a modified two-kidney, one-clip approach in mice is not dependent on the α1 or α2 Na-K-ATPase ouabain-binding site.
J. Lorenz, V. Lasko, M. Nieman, Thomas Damhoff +3 more
2011AJP - Renal Physiology27 citations Open access
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Knockout of the Na,K-ATPase α2-isoform in cardiac myocytes delays pressure overload-induced cardiac dysfunction.
Tara N Rindler, V. Lasko, M. Nieman, Motoi Okada +2 more
2013American Journal of Physiology. Heart and Circulatory Physiology26 citations Open access
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Amino terminus of cardiac myosin binding protein-C regulates cardiac contractility
Thomas L. Lynch, Mohit Kumar, James W. McNamara, D. Kuster +21 more
2021Journal of Molecular and Cellular Cardiology25 citations Open access
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Ablation of the calpain-targeted site in cardiac myosin binding protein-C is cardioprotective during ischemia-reperfusion injury
David Y. Barefield, James W. McNamara, Thomas L. Lynch, D. Kuster +16 more
2019Journal of Molecular and Cellular Cardiology25 citations Open access
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Functional dissection of myosin binding protein C phosphorylation
M. Gupta, J. Gulick, J. James, H. Osińska +2 more
2013Journal of Molecular and Cellular Cardiology25 citations Open access
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Knockout of the Na,K-ATPase α₂-isoform in the cardiovascular system does not alter basal blood pressure but prevents ACTH-induced hypertension.
Tara N Rindler, I. Dostanic, V. Lasko, M. Nieman +3 more
2011American Journal of Physiology. Heart and Circulatory Physiology25 citations Open access
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V2a Neurons Constrain Extradiaphragmatic Respiratory Muscle Activity at Rest
Victoria N. Jensen, Kari Seedle, Sarah M. Turner, J. Lorenz +1 more
2019eNeuro22 citations Open access
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In vivo definition of cardiac myosin-binding protein C’s critical interactions with myosin
Shenuarin Bhuiyan, Patrick M. McLendon, J. James, H. Osińska +4 more
2016Pflügers Archiv: European Journal of Physiology22 citations Open access
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SERCA2 Haploinsufficiency in a Mouse Model of Darier Disease Causes a Selective Predisposition to Heart Failure
V. Prasad, J. Lorenz, V. Lasko, M. Nieman +4 more
2015BioMed Research International22 citations Open access
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NBCe1 Na+-HCO3- cotransporter ablation causes reduced apoptosis following cardiac ischemia-reperfusion injury in vivo
Kanimozhi Vairamani, V. Prasad, Yi-Gang Wang, Wei Huang +4 more
2018World Journal of Cardiology19 citations Open access
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CLIC5 mutant mice are resistant to diet-induced obesity and exhibit gastric hemorrhaging and increased susceptibility to torpor.
Emily M. Bradford, Marian L. Miller, V. Prasad, M. Nieman +5 more
2010American Journal of Physiology. Regulatory Integrative and Comparative Physiology16 citations Open access
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