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T. Rustan · SciRah

Researcher profile · Semantic Scholar

T. Rustan

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T. Rustan — researcher profile on SciRah

h-index: 18
Works: 25
Citations: 1,377

Most-cited papers

Metabolic activation and deactivation of arylamine carcinogens by recombinant human NAT1 and polymorphic NAT2 acetyltransferases.
D. Hein, M. Doll, T. Rustan, Kevin Gray +3 more
1993Carcinogenesis362 citations
Semantic Scholar
Metabolic activation of N-hydroxyarylamines and N-hydroxyarylamides by 16 recombinant human NAT2 allozymes: effects of 7 specific NAT2 nucleic acid substitutions.
D. Hein, M. Doll, T. Rustan, Ronald J. Ferguson
1995Cancer Research136 citations
Semantic Scholar
Molecular genetics of human polymorphic N-acetyltransferase: enzymatic analysis of 15 recombinant wild-type, mutant, and chimeric NAT2 allozymes.
David W. Heln, Ronald J. Ferguson, M. Doll, T. Rustan +1 more
1994Human Molecular Genetics127 citations
Semantic Scholar
INCREASED GLYCEROL-3-PHOSPHORYLCHOUNE IN POST-MORTEM ALZHEIMER'S BRAIN
M. Bárány, Yen-Chung Chang, C. Arús, T. Rustan +1 more
1985103 citations
Semantic Scholar
Human N-acetylation of benzidine: role of NAT1 and NAT2.
T. Zenser, V. Lakshmi, T. Rustan, M. Doll +3 more
1996Cancer Research84 citations
Semantic Scholar
Rodent models of the human acetylation polymorphism: comparisons of recombinant acetyltransferases.
David W. Hein, M. Doll, A. Fretland, Kevin Gray +6 more
1997Mutation research72 citations
Semantic Scholar
Cloning of a gene whose expression is increased in scrapie and in senile plaques in human brain.
S. Wietgrefe, M. Zupancic, A. Haase, B. Chesebro +4 more
1985Science64 citations
Semantic Scholar
Identification of a novel allele at the human NAT1 acetyltransferase locus.
M. Doll, Wen Jiang, A. Deitz, T. Rustan +1 more
1997Biochemical and Biophysical Research Communications - BBRC63 citations Open access
Semantic Scholar
Metabolic activation of aromatic and heterocyclicN-hydroxyarylamines by wild-type and mutant recombinant human NAT1 and NAT2 acetyltransferases
D. Hein, T. Rustan, Ronald J. Ferguson, M. Doll +1 more
2007Archives of Toxicology60 citations
Semantic Scholar
Metabolic activation of N-hydroxy-2-aminofluorene and N-hydroxy-2-acetylaminofluorene by monomorphic N-acetyltransferase (NAT1) and polymorphic N-acetyltransferase (NAT2) in colon cytosols of Syrian hamsters congenic at the NAT2 locus.
D. Hein, M. Doll, Kevin Gray, T. Rustan +1 more
1993Cancer Research58 citations
Semantic Scholar
Prostate-specific human N-acetyltransferase 2 (NAT2) expression in the mouse.
M. A. Leff, Paul N. Epstein, M. Doll, A. Fretland +3 more
1999Journal of Pharmacology and Experimental Therapeutics54 citations
Semantic Scholar
Extrahepatic expression of the N-acetylation polymorphism toward arylamine carcinogens in tumor target organs of an inbred rat model.
D. Hein, T. Rustan, K. D. Bucher, Erik J. Furman +1 more
1991Journal of Pharmacology and Experimental Therapeutics45 citations
Semantic Scholar
Cloning, expression, and functional characterization of two mutant (NAT2(191) and NAT2(341/803)) and wild-type human polymorphic N-acetyltransferase (NAT2) alleles.
Ronald J. Ferguson, M. Doll, T. Rustan, Kevin Gray +1 more
1994Drug Metabolism And Disposition43 citations
Semantic Scholar
Acetyltransferases and susceptibility to chemicals.
D. W. Hein, T. Rustan, M. Doll, K. D. Bucher +4 more
1992Toxicology Letters43 citations
Semantic Scholar
Acetylator phenotype-dependent and -independent expression of arylamine N-acetyltransferase isozymes in rapid and slow acetylator inbred rat liver.
David W. Hein, T. Rustan, K. D. Bucher, W. Martin +1 more
1991Drug Metabolism And Disposition34 citations
Semantic Scholar
Cloning, expression, and functional characterization of rapid and slow acetylator polymorphic N-acetyl-transferase encoding genes of the Syrian hamster.
Ronald J. Ferguson, M. Doll, T. Rustan, David W. Hein
1996Pharmacogenetics (London)29 citations
Semantic Scholar
Purification of hepatic polymorphic arylamine N-acetyltransferase from homozygous rapid acetylator inbred hamster: identity with polymorphic N-hydroxyarylamine-O-acetyltransferase.
A. Trinidad, D. Hein, T. Rustan, Ronald J. Ferguson +5 more
1990Cancer Research28 citations
Semantic Scholar
Construction of Syrian hamster lines congenic at the polymorphic acetyltransferase locus (NAT2): acetylator genotype-dependent N- and O-acetylation of arylamine carcinogens.
D. W. Hein, M. Doll, T. Rustan, Kevin Gray +2 more
1994Toxicology and Applied Pharmacology26 citations
Semantic Scholar
Polymorphic and monomorphic expression of arylamine carcinogen N-acetyltransferase isozymes in tumor target organ cytosols of Syrian hamsters congenic at the polymorphic acetyltransferase locus.
David W. Hein, T. Rustan, K. D. Bucher, L. Miller
1991Journal of Pharmacology and Experimental Therapeutics26 citations
Semantic Scholar
Human brain tubulin purification: Decrease in soluble tubulin with age
S. C. Yan, Sutaeg Hwang, T. Rustan, William H Frey II
2004Neurochemical Research24 citations
Semantic Scholar
Higher frequency of aberrant crypt foci in rapid than slow acetylator inbred rats administered the colon carcinogen 3,2'-dimethyl-4-aminobiphenyl.
Yi Feng, A. Fretland, T. Rustan, Wen Jiang +2 more
1997Toxicology and Applied Pharmacology24 citations
Semantic Scholar
Syrian hamster monomorphic N-acetyltransferase (NAT1) alleles: amplification, cloning, sequencing, and expression in E. coli.
Ronald J. Ferguson, M. Doll, T. Rustan, Barbara R. Baumstark +1 more
1994Pharmacogenetics (London)24 citations
Semantic Scholar
Human acetylator genotype: Relationship to colorectal cancer incidence and arylamine N-acetyltransferase expression in colon cytosol
José W. Rodríguez, W. Kirlin, Ronald J. Ferguson, M. Doll +6 more
2005Archives of Toxicology23 citations
Semantic Scholar
Acetylator genotype-dependent N-acetylation of arylamines in vivo and in vitro by hepatic and extrahepatic organ cytosols of Syrian hamsters congenic at the polymorphic acetyltransferase locus
D. Hein, T. Rustan, W. Martin, K. D. Bucher +2 more
2006Archives of Toxicology8 citations
Semantic Scholar
Acetylator genotype-dependent formation of 2-aminofluorene-hemoglobin adducts in rapid and slow acetylator Syrian hamsters congenic at the NAT2 locus.
Yi Feng, T. Rustan, Ronald J. Ferguson, M. Doll +1 more
1994Toxicology and Applied Pharmacology8 citations
Semantic Scholar
Cloning of a gene whose expression is increased in scrapie and in senile plaques in human brain
S. Wietgrefe, M. Zupancic, A. Haase, B. Chesebro +4 more
19875 citations
Semantic Scholar
SCREENING METHOD FOR URINARY BLADDER TUMOR DETECTION IN THE SYRIAN HAMSTER
Yi Feng, T. Rustan, A. Fretland, A. M. Cooley +3 more
19991 citations
Semantic Scholar
Acetylator Genotype-Dependent Metabolic Activation of N-Hydroxy-2-Aminofluorene in Syrian Hamster Lines Congenic at the NAT2 Locus
D. Hein, M. Doll, T. Rustan, Kevin Gray +3 more
19941 citations
Semantic Scholar
- Acetyltransferase O-Hydroxyarylamine-N Hamster : Identity with Polymorphic-Acetyltransferase from Homozygous Rapid Acetylator Inbred N Purification of Hepatic Polymorphic Arylamine Updated
D. Hein, T. Rustan, Ronald J. Ferguson, L. Miller +4 more
20060 citations
Semantic Scholar
Prostate-Specific Human N-Acetyltransferase 2 ( NAT 2 ) Expression in the Mouse 1
M. A. Leff, Paul N. Epstein, M. Doll, A. Fretland +3 more
19990 citations
Semantic Scholar
A rapid and sensitive method for detection of urinary bladder tumors in rodents.
Yi Feng, T. Rustan, A. Fretland, A. M. Cooley +3 more
1998Proceedings of the Western Pharmacology Society0 citations
Semantic Scholar
DEMENTIA WITH NON‐SPECIFIC MULTISYSTEM DEGENERATION: 22
A. Mastri, William H Frey II, T. Rustan, Ho Sung Joo
19870 citations
Semantic Scholar

Frequent co-authors

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M. Doll×18
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M. Doll — researcher profile on SciRah
Ronald J. Ferguson×15
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Ronald J. Ferguson — researcher profile on SciRah
D. Hein×11
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Kevin Gray×10
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David W. Hein — researcher profile on SciRah

K. D. Bucher×7

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Erik J. Furman×5

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William H Frey II×4

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