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Shi-Long Zheng · SciRah

Researcher profile · Semantic Scholar

Shi-Long Zheng

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Shi-Long Zheng — researcher profile on SciRah

h-index: 24
Works: 71
Citations: 2,001

Most-cited papers

Histone Deacetylase Inhibitors in Clinical Studies as Templates for New Anticancer Agents
Madhusoodanan Mottamal, Shi-Long Zheng, Tien L. Huang, Guangdi Wang
2015Molecules635 citations Open access
Semantic Scholar
Design, Synthesis, and Biological Evaluation of Novel Pyridine-Bridged Analogues of Combretastatin-A4 as Anticancer Agents
Shi-Long Zheng, Q. Zhong, Madhusoodanan Mottamal, Qiang Zhang +4 more
2014Journal of Medicinal Chemistry110 citations Open access
Semantic Scholar
Ligands of Therapeutic Utility for the Liver X Receptors
Rajesh Komati, Dominick Spadoni, Shi-Long Zheng, Jayalakshmi Sridhar +2 more
2017Molecules100 citations Open access
Semantic Scholar
Fulvestrant-3 Boronic Acid (ZB716): An Orally Bioavailable Selective Estrogen Receptor Downregulator (SERD)
Jia-Wang Liu, Shi-Long Zheng, V. Akerstrom, C. Yuan +12 more
2016Journal of Medicinal Chemistry73 citations Open access
Semantic Scholar
Effects of 7-O Substitutions on Estrogenic and Antiestrogenic Activities of Daidzein Analogues in MCF-7 Breast Cancer Cells
Quan Jiang, Florastina Payton-Stewart, S. Elliott, Jennifer L. Driver +12 more
2010Journal of Medicinal Chemistry58 citations Open access
Semantic Scholar
Development of covalent inhibitors: Principle, design, and application in cancer
Lang Zheng, Yang Li, Defa Wu, Huan Xiao +3 more
2023MedComm - Oncology56 citations Open access
Semantic Scholar
Development of new estrogen receptor-targeting therapeutic agents for tamoxifen-resistant breast cancer
Quan Jiang, Shi-Long Zheng, Guangdi Wang
2013Future Medicinal Chemistry51 citations Open access
Semantic Scholar
Structure–Activity Relationship and Pharmacokinetic Studies of 1,5-Diheteroarylpenta-1,4-dien-3-ones: A Class of Promising Curcumin-Based Anticancer Agents
Rubing Wang, Chengsheng Chen, Xiaojie Zhang, Changde Zhang +6 more
2015Journal of Medicinal Chemistry50 citations Open access
Semantic Scholar
Design, synthesis, and evaluation of novel heteroaromatic analogs of curcumin as anti-cancer agents.
N. Samaan, Q. Zhong, J. Fernandez, Guanglin Chen +4 more
2014European journal of medicinal chemistry47 citations Open access
Semantic Scholar
Modification and Biological Evaluation of Thiazole Derivatives as Novel Inhibitors of Metastatic Cancer Cell Migration and Invasion
Shi-Long Zheng, Q. Zhong, Yulan Xi, Madhusoodanan Mottamal +6 more
2014Journal of Medicinal Chemistry47 citations Open access
Semantic Scholar
Discovery of a Series of Thiazole Derivatives as Novel Inhibitors of Metastatic Cancer Cell Migration and Invasion
Shi-Long Zheng, Q. Zhong, Quan Jiang, Madhusoodanan Mottamal +5 more
2013ACS Medicinal Chemistry Letters44 citations Open access
Semantic Scholar
Boron-Based 4-Hydroxytamoxifen Bioisosteres for Treatment of de Novo Tamoxifen Resistant Breast Cancer
Quan Jiang, Q. Zhong, Qiang Zhang, Shi-Long Zheng +1 more
2012ACS Medicinal Chemistry Letters35 citations Open access
Semantic Scholar
ZB716, a steroidal selective estrogen receptor degrader (SERD), is orally efficacious in blocking tumor growth in mouse xenograft models
Shanchun Guo, Changde Zhang, Melyssa R. Bratton, Madhusoodanan Mottamal +13 more
2018OncoTarget34 citations Open access
Semantic Scholar
Biocompatible Boron-Containing Prodrugs of Belinostat for the Potential Treatment of Solid Tumors.
Shi-Long Zheng, Shanchun Guo, Q. Zhong, Changde Zhang +4 more
2018ACS Medicinal Chemistry Letters34 citations Open access
Semantic Scholar
Boronic prodrug of 4-hydroxytamoxifen is more efficacious than tamoxifen with enhanced bioavailability independent of CYP2D6 status
Q. Zhong, Changde Zhang, Qiang Zhang, L. Miele +2 more
2015BMC Cancer34 citations Open access
Semantic Scholar
Rational Design of a Boron-Modified Triphenylethylene (GLL398) as an Oral Selective Estrogen Receptor Downregulator.
Jia-Wang Liu, Shi-Long Zheng, Shanchun Guo, Changde Zhang +7 more
2017ACS Medicinal Chemistry Letters33 citations Open access
Semantic Scholar
Silibinin Derivatives as Anti-Prostate Cancer Agents: Synthesis and Cell-Based Evaluations
Bao Vue, Shenmin Zhang, Xiaojie Zhang, Konstantinos Parisis +4 more
2015European journal of medicinal chemistry32 citations Open access
Semantic Scholar
A Ligand-Based Drug Design. Discovery of 4-Trifluoromethyl-7,8-pyranocoumarin as a Selective Inhibitor of Human Cytochrome P450 1A2
Jia-Wang Liu, P. T. Pham, E. Skripnikova, Shi-Long Zheng +11 more
2015Journal of Medicinal Chemistry32 citations Open access
Semantic Scholar
Novel daidzein analogs enhance osteogenic activity of bone marrow-derived mesenchymal stem cells and adipose-derived stromal/stem cells through estrogen receptor dependent and independent mechanisms
Amy L. Strong, Jason F. Ohlstein, Quan Jiang, Qiang Zhang +7 more
2014Stem cell research & therapeutics30 citations Open access
Semantic Scholar
Synthesis and anticancer activity evaluation of naphthalene-substituted triazole spirodienones
Lan Luo, Jing Jia, Q. Zhong, Xue Zhong +3 more
2020European journal of medicinal chemistry29 citations Open access
Semantic Scholar
Boronic Prodrug of Endoxifen as an Effective Hormone Therapy for Breast Cancer
Changde Zhang, Q. Zhong, Qiang Zhang, Shi-Long Zheng +2 more
2015Breast Cancer Research and Treatment29 citations Open access
Semantic Scholar
Design, synthesis, and osteogenic activity of daidzein analogs on human mesenchymal stem cells.
Amy L. Strong, Quan Jiang, Qiang Zhang, Shi-Long Zheng +5 more
2014ACS Medicinal Chemistry Letters27 citations Open access
Semantic Scholar
Synthesis and Evaluation of 1,7-Diheteroarylhepta-1,4,6-trien-3-ones as Curcumin-Based Anticancer Agents
Rubing Wang, Xiaojie Zhang, Chengsheng Chen, Guanglin Chen +5 more
2016European journal of medicinal chemistry24 citations Open access
Semantic Scholar
Design, Synthesis, and Evaluation of Genistein Analogues as Anti-Cancer Agents
Pahoua Xiong, Rubing Wang, Xiaojie Zhang, Eduardo DeLa Torre +5 more
2015Anti-Cancer Agents in Medicinal Chemistry24 citations Open access
Semantic Scholar
A new class of flavonol-based anti-prostate cancer agents: design, synthesis, and evaluation in cell models
Xiang Li, Guanglin Chen, Xiaojie Zhang, Qiang Zhang +3 more
2016Bioorganic & Medicinal Chemistry Letters22 citations Open access
Semantic Scholar
Small-molecule inhibitors of Wnt signaling pathway: towards novel anticancer therapeutics.
Shi-Long Zheng, Jia-Wang Liu, Yan-Yuan Wu, Tien L. Huang +1 more
2015Future Medicinal Chemistry22 citations Open access
Semantic Scholar
Design and synthesis of novel hydroxyanthraquinone nitrogen mustard derivatives as potential anticancer agents via a bioisostere approach
Li-Ming Zhao, Feng-Yan Ma, Hai-Shan Jin, Shi-Long Zheng +2 more
2015European journal of medicinal chemistry19 citations Open access
Semantic Scholar
Metabolism, pharmacokinetics, and bioavailability of ZB716, a Steroidal Selective Estrogen Receptor Downregulator (SERD)
Changde Zhang, Shanchun Guo, Lin Yang, Jia-Wang Liu +4 more
2017OncoTarget18 citations Open access
Semantic Scholar
Novel Anti-Cancer Stem Cell Compounds: A Comprehensive Review
Shanchun Guo, Shi-Long Zheng, Ming-Li Liu, Guangdi Wang
2024Pharmaceutics17 citations Open access
Semantic Scholar
Nitrogen-Containing Derivatives of O-Tetramethylquercetin: Synthesis and Biological Profiles in Prostate Cancer Cell Models
Pravien Rajaram, Zi-Ran Jiang, Guanglin Chen, Alyssa Rivera +5 more
2019Bioorganic chemistry (Print)17 citations Open access
Semantic Scholar
Copper salt-catalyzed formation of a novel series of triazole–spirodienone conjugates with potent anticancer activity
L. Gu, Peng Wang, Q. Zhong, Yu-Xing Deng +7 more
2017RSC Advances15 citations Open access
Semantic Scholar
Synthesis, biological evaluation and molecular docking studies of resveratrol derivatives possessing curcumin moiety as potent antitubulin agents.
B. Ruan, Xiang-Yong Lu, Tingyu Li, Jian-Feng Tang +5 more
2012Bioorganic & Medicinal Chemistry14 citations
Semantic Scholar
Design, synthesis, and antitumor activity evaluation of novel acyl sulfonamide spirodienones
Chen Chen, Yang Luo, H. Yin, Q. Zhong +5 more
2022Bioorganic & Medicinal Chemistry13 citations Open access
Semantic Scholar
Targeting of PP2Cδ By a Small Molecule C23 Inhibits High Glucose-Induced Breast Cancer Progression In Vivo
Ke Wu, Xiao-Ting Yu, Zhimin Huang, Donghui Zhu +13 more
2019Antioxidants and Redox Signaling13 citations Open access
Semantic Scholar
Discovery of Novel Allopurinol Derivatives with Anticancer Activity and Attenuated Xanthine Oxidase Inhibition
Yong Li, Tingting Cao, Shanchun Guo, Q. Zhong +6 more
2016Molecules13 citations Open access
Semantic Scholar
Development of a bioavailable boron-containing PI-103 Bioisostere, PI-103BE
Lan Luo, Q. Zhong, Shanchun Guo, Changde Zhang +4 more
2020Bioorganic & Medicinal Chemistry Letters12 citations Open access
Semantic Scholar
Metabolism and Pharmacokinetic Study of the Boron-Containing Prodrug of Belinostat (ZL277), a Pan HDAC Inhibitor with Enhanced Bioavailability
Changde Zhang, Shanchun Guo, Q. Zhong, Qiang Zhang +3 more
2019Pharmaceuticals12 citations Open access
Semantic Scholar
5- or/and 20-O-Alkyl-2,3-dehydrosilybins: Synthesis and biological profiles on prostate cancer cell models
Bao Vue, Xiaojie Zhang, Timmy Lee, N. Nair +6 more
2017Bioorganic & Medicinal Chemistry12 citations Open access
Semantic Scholar
Asymmetric 1,5-Diarylpenta-1,4-dien-3-ones: Antiproliferative Activity in Prostate Epithelial Cell Models and Pharmacokinetic Studies
Xiaojie Zhang, Shanchun Guo, Chengsheng Chen, G. Perez +12 more
2017European journal of medicinal chemistry11 citations Open access
Semantic Scholar
Structure-Activity Relationship and Pharmacokinetic Studies of 3-O-Substitutedflavonols as Anti-Prostate Cancer Agents
Xiang Li, Changde Zhang, Shanchun Guo, Pravien Rajaram +8 more
2018European journal of medicinal chemistry10 citations Open access
Semantic Scholar
O-Aminoalkyl-O-Trimethyl-2,3-Dehydrosilybins: Synthesis and In Vitro Effects Towards Prostate Cancer Cells
Bao Vue, Shenmin Zhang, Andre Vignau, Guanglin Chen +6 more
2018Molecules9 citations Open access
Semantic Scholar
Design, synthesis, and biological evaluation of 1,9-diheteroarylnona-1,3,6,8-tetraen-5-ones as a new class of anti-prostate cancer agents.
Xiaojie Zhang, Rubing Wang, G. Perez, Guanglin Chen +4 more
2016Bioorganic & Medicinal Chemistry9 citations Open access
Semantic Scholar
One-Pot Synthesis of Seven-Membered Heterocyclic Derivatives of Diazepines Involving Copper-Catalyzed Rearrangement Cascade Allyl-Amination
Yuepeng Chen, Xing-Lei Liu, Wei Q. Shi, Shi-Long Zheng +2 more
2020Journal of Organic Chemistry8 citations Open access
Semantic Scholar
Discovery of berberine analogs as potent and highly selective p300/CBP HAT inhibitors.
Xue Zhong, Hui-Wen Deng, Min Long, H. Yin +6 more
2023Bioorganic chemistry (Print)7 citations
Semantic Scholar
Synthesis and antiproliferative evaluation of new zampanolide mimics
Guanglin Chen, Manee Patanapongpibul, Zi-Ran Jiang, Qiang Zhang +4 more
2019Organic and biomolecular chemistry7 citations Open access
Semantic Scholar
Design, synthesis, and evaluation of a novel series of mono-indolylbenzoquinones derivatives for the potential treatment of breast cancer
Jing Jia, H. Yin, Chen Chen, Minglin Hu +7 more
2022European journal of medicinal chemistry6 citations Open access
Semantic Scholar
Optimized synthesis and antiproliferative activity of desTHPdactylolides
Guanglin Chen, Rubing Wang, Bao Vue, Manee Patanapongpibul +5 more
2018Bioorganic & Medicinal Chemistry6 citations Open access
Semantic Scholar
Structure-activity relationship studies of 1,7-diheteroarylhepta-1,4,6-trien-3-ones with two different terminal rings in prostate epithelial cell models.
Rubing Wang, Xiaojie Zhang, Chengsheng Chen, Guanglin Chen +5 more
2017European journal of medicinal chemistry6 citations Open access
Semantic Scholar
3-O-Substituted-3′,4′,5′-trimethoxyflavonols: synthesis and cell-based evaluation as anti-prostate cancer agents
Xiang Li, Maizie Lee, Guanglin Chen, Qiang Zhang +3 more
2017Bioorganic & Medicinal Chemistry6 citations Open access
Semantic Scholar
3-O-Alkyl-2,3-Dehydrosilibinins: Two Synthetic Approaches and in vitro Effects toward Prostate Cancer Cells
Sheng Zhang, Bao Vue, Michael Huang, Xiaojie Zhang +6 more
2016Bioorganic & Medicinal Chemistry Letters6 citations Open access
Semantic Scholar

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