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J. Gruschus · SciRah

Researcher profile · Semantic Scholar

J. Gruschus

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J. Gruschus — researcher profile on SciRah

h-index: 26
Works: 100
Citations: 1,849

Most-cited papers

α-Synuclein Interacts with Glucocerebrosidase Providing a Molecular Link between Parkinson and Gaucher Diseases*
Thai Leong Yap, J. Gruschus, A. Velayati, W. Westbroek +4 more
2011Journal of Biological Chemistry184 citations Open access
Semantic Scholar
Phosphoinositide-dependent Activation of the ADP-ribosylation Factor GTPase-activating Protein ASAP1
J. Kam, K. Miura, T. Jackson, J. Gruschus +5 more
2000Journal of Biological Chemistry130 citations Open access
Semantic Scholar
Histone H4 K16Q mutation, an acetylation mimic, causes structural disorder of its N-terminal basic patch in the nucleosome
Bing-Rui Zhou, H. Feng, R. Ghirlando, Hidenori Kato +2 more
2012Journal of Molecular Biology87 citations Open access
Semantic Scholar
Observation of a narrow superconducting transition at 6 GHz in crystals of YBa2Cu3O7.
David T. Rubin, K. Green, J. Gruschus, J. Kirchgessner +6 more
1988Physical Review B (Condensed Matter)87 citations
Semantic Scholar
Interactions of the vnd/NK-2 homeodomain with DNA by nuclear magnetic resonance spectroscopy: basis of binding specificity.
J. Gruschus, Désirée H. H. Tsao, Lan-Hsiang Wang, Marshall W. Nirenberg +1 more
1997Biochemistry78 citations
Semantic Scholar
Autoinhibition of Arf GTPase-activating Protein Activity by the BAR Domain in ASAP1*
X. Jian, P. Brown, P. Schuck, J. Gruschus +3 more
2009Journal of Biological Chemistry73 citations Open access
Semantic Scholar
Elongation of helix III of the NK-2 homeodomain upon binding to DNA: a secondary structure study by NMR.
Désirée H. H. Tsao, J. Gruschus, Lan-Hsiang Wang, Marshall W. Nirenberg +1 more
1994Biochemistry65 citations
Semantic Scholar
Molecular Basis for Cooperative Binding of Anionic Phospholipids to the PH Domain of the Arf GAP ASAP1
X. Jian, Wai-Kwan Tang, P. Zhai, N. Roy +8 more
2015Structure61 citations Open access
Semantic Scholar
Germ-line mutation of NKX3.1 cosegregates with hereditary prostate cancer and alters the homeodomain structure and function.
S. Zheng, J. Ju, B. Chang, E. Ortner +12 more
2006Cancer Research60 citations Open access
Semantic Scholar
Modifications to the C-terminus of Arf1 alter cell functions and protein interactions
X. Jian, M. Cavenagh, J. Gruschus, P. Randazzo +1 more
2010Traffic : the International Journal of Intracellular Transport57 citations Open access
Semantic Scholar
New Hamiltonian model for long-range electronic superexchange in complex molecular structures
J. Gruschus, A. Kuki
199356 citations
Semantic Scholar
The three-dimensional solution structure of the NK-2 homeodomain from Drosophila.
Désirée H. H. Tsao, J. Gruschus, Lan-Hsiang Wang, Marshall W. Nirenberg +1 more
1995Journal of Molecular Biology52 citations
Semantic Scholar
Structural Features of Membrane-bound Glucocerebrosidase and α-Synuclein Probed by Neutron Reflectometry and Fluorescence Spectroscopy*
Thai Leong Yap, Zhi-Ping Jiang, F. Heinrich, J. Gruschus +5 more
2014Journal of Biological Chemistry47 citations Open access
Semantic Scholar
Characterization of the N-terminal Tail Domain of Histone H3 in Condensed Nucleosome Arrays by Hydrogen Exchange and NMR
Hidenori Kato, J. Gruschus, R. Ghirlando, N. Tjandra +1 more
2009Journal of the American Chemical Society45 citations Open access
Semantic Scholar
Saposin C Protects Glucocerebrosidase against α-Synuclein Inhibition
Thai Leong Yap, J. Gruschus, A. Velayati, E. Sidransky +1 more
2013Biochemistry43 citations Open access
Semantic Scholar
Regulation of ASAP1 by phospholipids is dependent on the interface between the PH and Arf GAP domains.
M. M. Che, Emily Boja, H. Yoon, J. Gruschus +5 more
2005Cellular Signalling42 citations Open access
Semantic Scholar
The three-dimensional structure of the vnd/NK-2 homeodomain-DNA complex by NMR spectroscopy.
J. Gruschus, Désirée H. H. Tsao, Lan-Hsiang Wang, Marshall W. Nirenberg +1 more
1999Journal of Molecular Biology41 citations
Semantic Scholar
The Pleckstrin Homology (PH) Domain of the Arf Exchange Factor Brag2 Is an Allosteric Binding Site*
X. Jian, J. Gruschus, E. Sztul, P. Randazzo
2012Journal of Biological Chemistry35 citations Open access
Semantic Scholar
Site-directed Mutations in the vnd/NK-2 Homeodomain
S. Weiler, J. Gruschus, D. Tsao, Lei Yu +3 more
1998Journal of Biological Chemistry35 citations Open access
Semantic Scholar
Physical and functional interactions between the prostate suppressor homeoprotein NKX3.1 and serum response factor.
J. Ju, J. Maeng, M. Zemedkun, Natalie Ahronovitz +4 more
2006Journal of Molecular Biology29 citations
Semantic Scholar
NMR Structure of Calmodulin Complexed to an N-terminally Acetylated α-Synuclein Peptide
J. Gruschus, Thai Leong Yap, S. Pistolesi, Alexander S. Maltsev +1 more
2013Biochemistry28 citations Open access
Semantic Scholar
A Low pKa Cysteine at the Active Site of Mouse Methionine Sulfoxide Reductase A*
Jung-Chae Lim, J. Gruschus, Geumsoo Kim, B. Berlett +2 more
2012Journal of Biological Chemistry28 citations Open access
Semantic Scholar
Structure of the functional fragment of auxilin required for catalytic uncoating of clathrin-coated vesicles.
J. Gruschus, Chaehyeok Han, T. Greener, J. Ferretti +2 more
2004Biochemistry28 citations
Semantic Scholar
Dissociation of glucocerebrosidase dimer in solution by its co-factor, saposin C
J. Gruschus, Zhi-Ping Jiang, Thai Leong Yap, S. A. Hill +4 more
2015Biochemical and Biophysical Research Communications - BBRC26 citations Open access
Semantic Scholar
Mutations that affect the ability of the vnd/NK-2 homeoprotein to regulate gene expression: Transgenic alterations and tertiary structure
K. Koizumi, C. Lintas, M. Nirenberg, J. Maeng +5 more
2003Proceedings of the National Academy of Sciences of the United States of America26 citations Open access
Semantic Scholar
The Escherichia coli adenylyl cyclase complex: requirement of PTS proteins for stimulation by nucleotides.
A. Peterkofsky, Y. Seok, N. Amin, R. Thapar +6 more
1995Biochemistry26 citations
Semantic Scholar
Dynamic interaction between Arf GAP and PH domains of ASAP1 in the regulation of GAP activity
Ruibai Luo, L. M. Miller Jenkins, P. Randazzo, J. Gruschus
2008Cellular Signalling25 citations Open access
Semantic Scholar
Segmental Deuteration of α-Synuclein for Neutron Reflectometry on Tethered Bilayers
Zhi-Ping Jiang, F. Heinrich, R. McGlinchey, J. Gruschus +1 more
2016Journal of Physical Chemistry Letters24 citations Open access
Semantic Scholar
Probing Fibril Dissolution of the Repeat Domain of a Functional Amyloid, Pmel17, on the Microscopic and Residue Level
R. McGlinchey, J. Gruschus, A. Nagy, Jennifer C. Lee
2011Biochemistry22 citations Open access
Semantic Scholar
Mutagenesis and modeling of the peroxiredoxin (Prx) complex with the NMR structure of ATP-bound human sulfiredoxin implicate aspartate 187 of Prx I as the catalytic residue in ATP hydrolysis.
Duck-Yeon Lee, Sung Jun Park, W. Jeong, Ho-Jin Sung +4 more
2006Biochemistry22 citations
Semantic Scholar
Effect of mutating the regulatory phosphoserine and conserved threonine on the activity of the expressed catalytic domain of Acanthamoeba myosin I heavy chain kinase.
Joanna Szczepanowska, Umamaheswari Ramachandran, Christopher J. Herring, J. Gruschus +3 more
1998Proceedings of the National Academy of Sciences of the United States of America20 citations Open access
Semantic Scholar
Evidence of natural selection in the mitochondrial-derived peptides humanin and SHLP6
J. Gruschus, Daniel L. Morris, N. Tjandra
2023Scientific Reports18 citations Open access
Semantic Scholar
Do Amyloid Oligomers Act As Traps for Misfolded Proteins? A Hypothesis
J. Gruschus
2008Amyloid: Journal of Protein Folding Disorders18 citations Open access
Semantic Scholar
Intramolecular interaction in the tail of Acanthamoeba myosin IC between the SH3 domain and a putative pleckstrin homology domain
Kae-Jung Hwang, F. Mahmoodian, J. Ferretti, E. Korn +1 more
2007Proceedings of the National Academy of Sciences of the United States of America17 citations Open access
Semantic Scholar
Experimentally biased model structure of the Hsc70/auxilin complex: Substrate transfer and interdomain structural change
J. Gruschus, L. Greene, E. Eisenberg, James A. Ferretti
2004Protein Science17 citations Open access
Semantic Scholar
Characterization and Solution Structure of Mouse Myristoylated Methionine Sulfoxide Reductase A*
Jung-Chae Lim, J. Gruschus, B. Ghesquière, Geumsoo Kim +3 more
2012Journal of Biological Chemistry16 citations Open access
Semantic Scholar
Quantitative measurement of water diffusion lifetimes at a protein/DNA interface by NMR
J. Gruschus, J. Ferretti
2001Journal of Biomolecular NMR16 citations
Semantic Scholar
Allosteric properties of PH domains in Arf regulatory proteins
N. Roy, M. Yohe, P. Randazzo, J. Gruschus
2016Cellular Logistics14 citations Open access
Semantic Scholar
Cardiac-specific Nkx2.5 homeodomain: conformational stability and specific DNA binding of Nkx2.5(C56S).
E. Fodor, James W. Mack, J. Maeng, J. Ju +4 more
2005Biochemistry14 citations
Semantic Scholar
Partial charges by multipole constraint. Application to the amino acids
J. Gruschus, A. Kuki
199014 citations
Semantic Scholar
Tubulin code eraser CCP5 binds branch glutamates by substrate deformation
Jiayi Chen, E. Zehr, J. Gruschus, A. Szyk +4 more
2024Nature13 citations
Semantic Scholar
Did α-Synuclein and Glucocerebrosidase Coevolve? Implications for Parkinson’s Disease
J. Gruschus
2015PLoS ONE11 citations Open access
Semantic Scholar
Smoluchowski dynamics of the vnd/NK-2 homeodomain from Drosophila melanogaster: first-order mode-coupling approximation.
G. La Penna, Michele Mormino, Franco Pioli, A. Perico +3 more
1999Biopolymers11 citations
Semantic Scholar
15N-edited three-dimensional NOESY-HMQC with water flipback: enhancement of weak labile 1H resonances of protein side chains contacting DNA.
J. Gruschus, James A. Ferretti
1998Journal of magnetic resonance (San Diego, Calif. 1997 : Print)11 citations
Semantic Scholar
Ellipsoidal Delocalization of Tunneling Electrons in Long-Range Electron Transfer Proteins
J. Gruschus, A. Kuki
199910 citations
Semantic Scholar
Interactions of The Acidic Domain and SRF Interacting Motifs with the NKX3.1 Homeodomain
J. Ju, J. Maeng, Duck-Yeon Lee, G. Piszczek +2 more
2009Biochemistry9 citations Open access
Semantic Scholar
NMR Solution Structure of the Recombinant Fragment Containing Three Fibrin-Binding CR Domains of the Very Low Density Lipoprotein Receptor
Koyeli Banerjee, S. Yakovlev, J. Gruschus, L. Medved +1 more
2018Biochemistry8 citations Open access
Semantic Scholar
Backbone dynamics for the wild type and a double H52R/T56W mutant of the vnd/NK-2 homeodomain from Drosophila melanogaster.
Simone Fausti, Solly Weiler, C. Cuniberti, Kae-Jung Hwang +5 more
2001Biochemistry7 citations
Semantic Scholar
15N-1H Scalar Coupling Perturbation: An Additional Probe for Measuring Structural Changes Due to Ligand Binding
Junhe Ma, J. Gruschus, N. Tjandra
2009Journal of the American Chemical Society6 citations Open access
Semantic Scholar
Signal Enhancement Using 45° Water Flipback for 3D 15N-Edited ROESY and NOESY HMQC and HSQC
J. Gruschus, J. Ferretti
19996 citations
Semantic Scholar

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