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O. Le Bacquer · SciRah

Researcher profile · Semantic Scholar

O. Le Bacquer

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O. Le Bacquer — researcher profile on SciRah

h-index: 21
Works: 73
Citations: 4,841

Most-cited papers

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
J. Dupuis, C. Langenberg, I. Prokopenko, R. Saxena +303 more
2010Nature Genetics2,265 citations Open access
Semantic Scholar
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge
R. Saxena, M. Hivert, C. Langenberg, Toshiko Tanaka +150 more
2010Nature Genetics672 citations Open access
Semantic Scholar
Elevated sensitivity to diet-induced obesity and insulin resistance in mice lacking 4E-BP1 and 4E-BP2.
O. Le Bacquer, E. Petroulakis, S. Paglialunga, F. Poulin +3 more
2007Journal of Clinical Investigation364 citations Open access
Semantic Scholar
mTOR signaling: implications for cancer and anticancer therapy
E. Petroulakis, Y. Mamane, O. Le Bacquer, D. Shahbazian +1 more
2005British Journal of Cancer227 citations Open access
Semantic Scholar
S6K1 Plays a Critical Role in Early Adipocyte Differentiation
L. Carnevalli, K. Masuda, F. Frigerio, O. Le Bacquer +6 more
2010Developmental Cell203 citations Open access
Semantic Scholar
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk (vol 42, pg 105, 2010)
J. Dupuis, C. Langenberg, I. Prokopenko, R. Saxena +300 more
2010114 citations
Semantic Scholar
Manipulation of citrulline availability in humans.
C. Rougé, Clotilde Des Robert, Alexander Robins, O. Le Bacquer +3 more
2007American Journal of Physiology - Gastrointestinal and Liver Physiology97 citations
Semantic Scholar
Inflammatory Role of Toll-Like Receptors in Human and Murine Adipose Tissue
O. Poulain-Godefroy, O. Le Bacquer, Pauline Plancq, C. Lecoeur +3 more
2010Mediators of Inflammation87 citations Open access
Semantic Scholar
Glutamine preserves protein synthesis and paracellular permeability in Caco-2 cells submitted to "luminal fasting".
O. Le Bacquer, C. Laboisse, D. Darmaun
2003American Journal of Physiology - Gastrointestinal and Liver Physiology79 citations
Semantic Scholar
TCF7L2 rs7903146 impairs islet function and morphology in non-diabetic individuals
O. Le Bacquer, J. Kerr-Conte, S. Gargani, N. Delalleau +5 more
2012Diabetologia73 citations Open access
Semantic Scholar
TCF7L2 splice variants have distinct effects on beta-cell turnover and function.
O. Le Bacquer, L. Shu, M. Marchand, B. Neve +5 more
2011Human Molecular Genetics72 citations
Semantic Scholar
Vitamin D status modulates mitochondrial oxidative capacities in skeletal muscle: role in sarcopenia
J. Salles, A. Chanet, C. Guillet, A. M. Vaes +16 more
2022Communications Biology65 citations Open access
Semantic Scholar
Acute Effects of Intravenous Glutamine Supplementation on Protein Metabolism in Very Low Birth Weight Infants: A Stable Isotope Study
Clotilde Des Robert, O. Le Bacquer, H. Piloquet, J. Rozé +1 more
2002Pediatric Research44 citations
Semantic Scholar
Regulation and functional effects of ZNT8 in human pancreatic islets.
B. Lefebvre, B. Vandewalle, A. Balavoine, G. Quéniat +7 more
2012Journal of Endocrinology42 citations Open access
Semantic Scholar
Effects of glutamine deprivation on protein synthesis in a model of human enterocytes in culture.
O. Le Bacquer, Hassan Nazih, Hervé M. Blottiére, Dominique Meynial-Denis +2 more
2001American Journal of Physiology - Gastrointestinal and Liver Physiology42 citations
Semantic Scholar
mTOR signaling: implications for cancer and anticancer therapy.
E. Petroulakis, Y. Mamane, O. Le Bacquer, D. Shahbazian +1 more
2007British Journal of Cancer40 citations
Semantic Scholar
mTORC1 and mTORC2 regulate insulin secretion through Akt in INS-1 cells.
O. Le Bacquer, G. Quéniat, V. Gmyr, J. Kerr-Conte +2 more
2013Journal of Endocrinology36 citations Open access
Semantic Scholar
Alternative human liver transcripts of TCF7L2 bind to the gluconeogenesis regulator HNF4α at the protein level
B. Neve, O. Le Bacquer, S. Caron, Marlène Huyvaert +6 more
2014Diabetologia35 citations Open access
Semantic Scholar
Anabolic Properties of Mixed Wheat-Legume Pasta Products in Old Rats: Impact on Whole-Body Protein Retention and Skeletal Muscle Protein Synthesis
I. Berrazaga, J. Salles, K. Laleg, C. Guillet +11 more
2020Nutrients26 citations Open access
Semantic Scholar
Formulation, process conditions, and biological evaluation of dairy mixed gels containing fava bean and milk proteins: Effect on protein retention in growing young rats.
I. Berrazaga, Jean-luc Mession, K. Laleg, J. Salles +9 more
2019Journal of Dairy Science26 citations Open access
Semantic Scholar
4E‐BP1 and 4E‐BP2 double knockout mice are protected from aging‐associated sarcopenia
O. Le Bacquer, Kristell Combe, V. Patrac, B. Ingram +9 more
2019Journal of Cachexia, Sarcopenia and Muscle25 citations Open access
Semantic Scholar
Pea Proteins Have Anabolic Effects Comparable to Milk Proteins on Whole Body Protein Retention and Muscle Protein Metabolism in Old Rats
J. Salles, C. Guillet, O. Le Bacquer, Carmen Malnero-Fernandez +9 more
2021Nutrients21 citations Open access
Semantic Scholar
Acute rimonabant treatment promotes protein synthesis in C2C12 myotubes through a CB1‐independent mechanism
O. Le Bacquer, Kassandra Lanchais, Kristell Combe, L. van den Berghe +1 more
2020Journal of Cellular Physiology20 citations
Semantic Scholar
Deleterious Effect of High-Fat Diet on Skeletal Muscle Performance Is Prevented by High-Protein Intake in Adult Rats but Not in Old Rats
E. Poggiogalle, F. Rossignon, Aude Carayon, F. Capel +11 more
2022Frontiers in Physiology19 citations Open access
Semantic Scholar
Alterations of the endocannabinoid system and circulating and peripheral tissue levels of endocannabinoids in sarcopenic rats
O. Le Bacquer, J. Salles, F. Piscitelli, Phelipe Sanchez +4 more
2021Journal of Cachexia, Sarcopenia and Muscle19 citations Open access
Semantic Scholar
Protein restriction and dexamethasone as a model of protein hypercatabolism in dogs: effect of glutamine on leucine turnover.
B. Humbert, O. Le Bacquer, Patrick Nguyen, H. Dumon +1 more
2001Metabolism: Clinical and Experimental16 citations
Semantic Scholar
TCF 7 L 2 splice variants have distinct effects on b-cell turnover and function
O. Le Bacquer, Shu-Yi Luan, M. Marchand, B. Neve +5 more
201115 citations
Semantic Scholar
Cannabidiol protects C2C12 myotubes against cisplatin-induced atrophy by regulating oxidative stress.
O. Le Bacquer, Phelipe Sanchez, V. Patrac, César Rivoirad +4 more
2024American Journal of Physiology - Cell Physiology14 citations Open access
Semantic Scholar
Muscle metabolic alterations induced by genetic ablation of 4E-BP1 and 4E-BP2 in response to diet-induced obesity.
O. Le Bacquer, Kristell Combe, C. Montaurier, J. Salles +9 more
2017Molecular Nutrition & Food Research13 citations
Semantic Scholar
Acute depletion of plasma glutamine increases leucine oxidation in prednisone-treated humans.
O. Le Bacquer, N. Mauras, S. Welch, M. Haymond +1 more
2007Clinical Nutrition13 citations Open access
Semantic Scholar
Associating Inulin with a Pea Protein Improves Fast-Twitch Skeletal Muscle Mass and Muscle Mitochondrial Activities in Old Rats
J. Salles, M. Gueugneau, V. Patrac, Carmen Malnero-Fernandez +10 more
2023Nutrients11 citations Open access
Semantic Scholar
Determination of citrulline in human plasma, red blood cells and urine by electron impact (EI) ionization gas chromatography-mass spectrometry.
C. Rougé, Clotilde Des Robert, Alexander Robins, O. Le Bacquer +2 more
2008Journal of chromatography. B, Analytical technologies in the biomedical and life sciences11 citations
Semantic Scholar
Inhibition of the endocannabinoid system reverses obese phenotype in aged mice and partly restores skeletal muscle function.
Lucas Fajardo, Phelipe Sanchez, J. Salles, Jean-Paul Rigaudière +6 more
2023American Journal of Physiology. Endocrinology and Metabolism9 citations Open access
Semantic Scholar
Quand la traduction sort de sa TORpeur
O. Le Bacquer, Y. Martineau, Y. Mamane
20067 citations Open access
Semantic Scholar
Relationship between muscular mass, inflammatory status, tumor metabolic activity and oral intake in head and neck cancer at the outset of management.
M. Rey, O. Le Bacquer, A. Mulliez, Justine Bécaud +5 more
2025Clinical Nutrition ESPEN6 citations Open access
Semantic Scholar
Dietary leucine intake and sarcopenia: from isolated supplementation to combined strategies.
Stéphane Walrand, O. Le Bacquer
2025Current opinion in clinical nutrition and metabolic care4 citations
Semantic Scholar
Nutritional strategies against skeletal muscle wasting in cancer-associated cachexia: the role of β-hydroxybutyrate and polyunsaturated fatty acids
Benjamin Hay, A. Brun, A. Fougerat, V. Mazurak +3 more
2025Translational Oncology3 citations Open access
Semantic Scholar
[When translation arises from its TORpor].
O. Le Bacquer, Y. Martineau, Y. Mamane
2006Medecine sciences : M/S2 citations
Semantic Scholar
Endocannabinoid system and skeletal muscle health: Insights from cannabidiol
Anaïs Deglos, N. Saroul, S. Walrand, O. Le Bacquer
2026Molecular Metabolism1 citations Open access
Semantic Scholar
Refeeding syndrome in head and neck cancers: a risk in the prehabilitation of patients?
Roy Alhallak, Emma Estoup, S. Adelou, Justine Bécaud +7 more
2025Supportive Care in Cancer1 citations
Semantic Scholar
Chemotherapy-dependent effect of cannabidiol on skeletal muscle atrophy in a model of myotubes in culture
L. Pumain, V. Patrac, N. Saroul, S. Walrand +1 more
2024Clinical Nutrition ESPEN1 citations Open access
Semantic Scholar
Molecular Mechanisms of Postmeal Regulation of Muscle Anabolism
O. Le Bacquer
2019Nutrition and Skeletal Muscle1 citations
Semantic Scholar
Régulation nutritionnelle des fonctions entérocytaires
O. Le Bacquer, B. Humbert, D. Darmaun
20021 citations
Semantic Scholar
Lipidomic profile analysis reveals new links to sarcopenic obesity criteria in the OBESAR cohort
F. Capel, A. Pinel, M. Pouget, A. Mulliez +7 more
2025Clinical Nutrition ESPEN0 citations
Semantic Scholar
Système endocannabinoïde et santé musculaire : focus sur le potentiel du cannabididiol
Anaïs Deglos, N. Saroul, S. Walrand, O. Le Bacquer
2025Cahiers de Nutrition et de Diététique0 citations Open access
Semantic Scholar
Effects of dietary camelina oil intake on skeletal muscle metabolism and sarcopenia in older mice
Jean-Paul Rigaudière, Christophe Montaurier, Philippe Denis, O. Le Bacquer +6 more
2025Journal of physiology and biochemistry0 citations
Semantic Scholar
Endocannabinoids as potential biomarkers of sarcopenia obesity in patients with severe obesity
O. Le Bacquer, A. Pinel, M. Pouget, F. Capel +5 more
2025Clinical Nutrition ESPEN0 citations
Semantic Scholar
Cannabidiol Prevents Cisplatin-Induced Atrophy In A Model Of Myotubes In Culture
P. Sanchez, O. Le Bacquer
2023Clinical Nutrition ESPEN0 citations
Semantic Scholar
Le cannabidiol prévient l’atrophie induite par le cisplatine dans un modèle de myotubes en culture
P. Sánchez, C. Rivoirard, C. Polge, L. Combaret +1 more
2023Nutrition clinique et metabolisme0 citations
Semantic Scholar
Un entraînement excentrique excessif chez des souris carencées en vitamine D conduit à une perte de capacités physiques, une atrophie musculaire et une inflammation systémique
C. Norgieux, E. Burban, C. Giraudet, V. Patrac +6 more
2023Nutrition clinique et metabolisme0 citations
Semantic Scholar

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