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R. Pinyol · SciRah

Researcher profile · Semantic Scholar

R. Pinyol

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R. Pinyol — researcher profile on SciRah

h-index: 28
Works: 91
Citations: 7,716

Most-cited papers

Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets
K. Schulze, S. Imbeaud, E. Letouzé, L. Alexandrov +20 more
2015Nature Genetics1,658 citations Open access
Semantic Scholar
NASH limits anti-tumour surveillance in immunotherapy-treated HCC
D. Pfister, N. Núñez, R. Pinyol, O. Govaere +106 more
2021Nature1,148 citations Open access
Semantic Scholar
Molecular pathogenesis and systemic therapies for hepatocellular carcinoma
J. Llovet, R. Pinyol, R. Kelley, A. El-Khoueiry +4 more
2022Nature Cancer429 citations Open access
Semantic Scholar
DNA Methylation-Based Prognosis and Epidrivers in Hepatocellular Carcinoma
A. Villanueva, A. Portela, S. Sayols, C. Battiston +13 more
2015Hepatology392 citations Open access
Semantic Scholar
Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer
Mohsen Malehmir, D. Pfister, S. Gallage, M. Szydlowska +63 more
2019Nature Medicine382 citations Open access
Semantic Scholar
Adjuvant and neoadjuvant immunotherapies in hepatocellular carcinoma
J. Llovet, R. Pinyol, M. Yarchoan, Amit G. Singal +5 more
2024Nature Reviews Clinical Oncology368 citations Open access
Semantic Scholar
Massive parallel sequencing uncovers actionable FGFR2–PPHLN1 fusion and ARAF mutations in intrahepatic cholangiocarcinoma
D. Sia, B. Losic, Agrin Moeini, L. Cabellos +19 more
2015Nature Communications298 citations Open access
Semantic Scholar
Molecular predictors of prevention of recurrence in HCC with sorafenib as adjuvant treatment and prognostic factors in the phase 3 STORM trial
R. Pinyol, R. Montal, L. Bassaganyas, D. Sia +26 more
2018Gut292 citations Open access
Semantic Scholar
Cordon-bleu is an actin nucleation factor and controls neuronal morphology.
R. Ahuja, R. Pinyol, N. Reichenbach, Laura M Custer +3 more
2007Cell287 citations Open access
Semantic Scholar
Molecular Classification and Therapeutic Targets in Extrahepatic Cholangiocarcinoma
R. Montal, D. Sia, C. Montironi, W. Leow +25 more
2020Journal of Hepatology273 citations Open access
Semantic Scholar
Inflamed and non-inflamed classes of HCC: a revised immunogenomic classification
C. Montironi, F. Castet, Philipp K. Haber, R. Pinyol +25 more
2022Gut219 citations Open access
Semantic Scholar
Immune exclusion-Wnt/CTNNB1 class predicts resistance to immunotherapies in HCC
R. Pinyol, D. Sia, J. Llovet
2019Clinical Cancer Research215 citations Open access
Semantic Scholar
Molecular characterisation of hepatocellular carcinoma in patients with non-alcoholic steatohepatitis
R. Pinyol, S. Torrecilla, Huan Wang, C. Montironi +31 more
2021Journal of Hepatology214 citations Open access
Semantic Scholar
CXCR2 inhibition enables NASH-HCC immunotherapy
J. Leslie, J. B. Mackey, T. Jamieson, E. Ramon‐Gil +42 more
2022Gut191 citations Open access
Semantic Scholar
EHD proteins associate with syndapin I and II and such interactions play a crucial role in endosomal recycling.
A. Braun, R. Pinyol, Regina Dahlhaus, Dennis Koch +4 more
2005Molecular Biology of the Cell176 citations Open access
Semantic Scholar
F-BAR Proteins of the Syndapin Family Shape the Plasma Membrane and Are Crucial for Neuromorphogenesis
Elavarasi Dharmalingam, A. Haeckel, R. Pinyol, Lukas Schwintzer +3 more
2009Journal of Neuroscience123 citations Open access
Semantic Scholar
IGF2 Is Up-regulated by Epigenetic Mechanisms in Hepatocellular Carcinomas and Is an Actionable Oncogene Product in Experimental Models
Iris Martinez-Quetglas, R. Pinyol, D. Dauch, S. Torrecilla +12 more
2016Gastroenterology116 citations Open access
Semantic Scholar
Regulation of N-WASP and the Arp2/3 Complex by Abp1 Controls Neuronal Morphology
R. Pinyol, A. Haeckel, A. Ritter, B. Qualmann +1 more
2007PLoS ONE107 citations Open access
Semantic Scholar
Liver Injury Increases the Incidence of HCC following AAV Gene Therapy in Mice.
Dhwanil A. Dalwadi, L. Torrens, J. Abril-Fornaguera, R. Pinyol +7 more
2020Molecular Therapy93 citations Open access
Semantic Scholar
Molecular portrait of high alpha-fetoprotein in hepatocellular carcinoma: implications for biomarker-driven clinical trials
R. Montal, C. Andreu-Oller, L. Bassaganyas, R. Esteban-Fabró +11 more
2019British Journal of Cancer83 citations Open access
Semantic Scholar
An Immune Gene Expression Signature Associated With Development of Human Hepatocellular Carcinoma Identifies Mice That Respond to Chemopreventive Agents
Agrin Moeini, S. Torrecilla, V. Tovar, C. Montironi +11 more
2019Gastroenterology81 citations Open access
Semantic Scholar
Cabozantinib enhances anti-PD1 activity and elicits a neutrophil-based immune response in hepatocellular carcinoma
R. Esteban-Fabró, Catherine E. Willoughby, M. Piqué-Gili, C. Montironi +9 more
2022Clinical Cancer Research69 citations Open access
Semantic Scholar
The role of NEDD1 phosphorylation by Aurora A in chromosomal microtubule nucleation and spindle function.
R. Pinyol, Jacopo Scrofani, I. Vernos
2013Current Biology66 citations Open access
Semantic Scholar
Single-cell RNA sequencing-derived signatures define response patterns to atezolizumab + bevacizumab in advanced hepatocellular carcinoma
S. Cappuyns, M. Piqué-Gili, R. Esteban-Fabró, G. Philips +37 more
2024Journal of Hepatology61 citations Open access
Semantic Scholar
Copy number alteration burden differentially impacts immune profiles and molecular features of hepatocellular carcinoma
L. Bassaganyas, R. Pinyol, R. Esteban-Fabró, L. Torrens +10 more
2020Clinical Cancer Research54 citations Open access
Semantic Scholar
Molecular Profiling of Liver Tumors: Classification and Clinical Translation for Decision Making
R. Pinyol, J. Nault, I. Quetglas, J. Zucman-Rossi +1 more
2014Seminars in liver disease (Print)50 citations
Semantic Scholar
TERT promoter mutations: gatekeeper and driver of hepatocellular carcinoma.
R. Pinyol, V. Tovar, J. Llovet
2014Journal of Hepatology46 citations Open access
Semantic Scholar
Human-correlated genetic models identify precision therapy for liver cancer
Miryam Müller, S. May, Holly Hall, T. Kendall +45 more
2025Nature35 citations Open access
Semantic Scholar
R‐spondin 2 Drives Liver Tumor Development in a Yes‐Associated Protein‐Dependent Manner
C. Conboy, Germán L Vélez-Reyes, Barbara R Tschida, Hsiangyu Hu +15 more
2019Hepatology Communications23 citations Open access
Semantic Scholar
Integration of genomic information in the clinical management of HCC
I. Quetglas, Agrin Moeini, R. Pinyol, J. Llovet
2014Best practice & research. Clinical gastroenterology23 citations
Semantic Scholar
Genome-scale metabolic models for hepatocellular carcinoma
R. Pinyol, J. Llovet
2014Nature reviews: Gastroenterology & hepatology16 citations
Semantic Scholar
Identification of IGF2 as Genomic Driver and Actionable Therapeutic Target in Hepatoblastoma
J. Abril-Fornaguera, L. Torrens, C. Andreu-Oller, Juan Carrillo-Reixach +25 more
2023Molecular Cancer Therapeutics15 citations Open access
Semantic Scholar
Activated ATF6α is a hepatic tumour driver restricting immunosurveillance
Xin Li, Cynthia Lebeaupin, Aikaterini Kadianaki, Clementine Druelle-Cedano +94 more
2026Nature14 citations Open access
Semantic Scholar
Hallmarks of liver cancer: Therapeutic implications
J. Llovet, R. Pinyol, S. Affò, M. Yarchoan +5 more
2026Cell13 citations Open access
Semantic Scholar
Corrigendum to 'Molecular characterisation of hepatocellular carcinoma in patients with non-alcoholic steatohepatitis' [J Hepatol 75 (2021) 865-878].
R. Pinyol, S. Torrecilla, Huan Wang, C. Montironi +31 more
2021Journal of Hepatology13 citations Open access
Semantic Scholar
Capillary electrophoresis method for the enzymatic assay of galactosyltransferases with postreaction derivatization.
A. Monegal, R. Pinyol, A. Planas
2005Analytical Biochemistry13 citations
Semantic Scholar
Mutational scanning reveals oncogenic CTNNB1 mutations have diverse effects on signaling
Anagha Krishna, A. Meynert, K. S. Dolt, Martijn J. E. Kelder +23 more
2026Nature Genetics11 citations Open access
Semantic Scholar
Hepatocellular carcinoma hosts cholinergic neural cells and tumoral hepatocytes harboring targetable muscarinic receptors
Charlotte A. Hernandez, Claire Verzeroli, A. A. Roca-Suarez, Abud J. Farca-Luna +21 more
2024JHEP Reports11 citations Open access
Semantic Scholar
E7386 Enhances Lenvatinib’s Antitumor Activity in Preclinical Models and Human Hepatocellular Carcinoma
A. Mesropian, A. Gris-Oliver, U. Balaseviciute, Alka A. Potdar +22 more
2025Clinical Cancer Research9 citations
Semantic Scholar
Author Correction: Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer
Mohsen Malehmir, D. Pfister, S. Gallage, M. Szydlowska +63 more
2022Nature Medicine8 citations Open access
Semantic Scholar
Artificial intelligence predicts outcome-related molecular profiles and vascular invasion in hepatocellular carcinoma
T. Seraphin, A. Mesropian, Laura Žigutytė, J. Brooks +14 more
2025JHEP Reports7 citations
Semantic Scholar
Oncogenic role of PMEPA1 and its association with immune exhaustion and TGF-β activation in HCC
M. Piqué-Gili, C. Andreu-Oller, A. Mesropian, R. Esteban-Fabró +20 more
2024JHEP Reports7 citations Open access
Semantic Scholar
Tcf20 deficiency is associated with increased liver fibrogenesis and alterations in mitochondrial metabolism in mice and humans
Bernat Córdoba-Jover, Jordi Ribera, Irene Portolés, Elena Lecue +21 more
2023Liver international (Print)7 citations Open access
Semantic Scholar
Molecular portrait of high alpha-fetoprotein in hepatocellular carcinoma: implications for biomarker-driven clinical trials
R. Montal, C. Andreu-Oller, L. Bassaganyas, R. Esteban-Fabró +11 more
2019British Journal of Cancer5 citations Open access
Semantic Scholar
Molecular predictors of recurrence prevention with sorafenib as adjuvant therapy in hepatocellular carcinoma: Biomarker study of the STORM phase III trial
R. Pinyol, R. Montal, T. Takayama, G. Chau +26 more
20175 citations
Semantic Scholar
Molecular insights into early malignant transition of hepatocellular carcinoma
Zhengtao Zhang, Hong Li, Ling-Li Chen, Tao Lu +18 more
2026Cancer Cell3 citations Open access
Semantic Scholar
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
U. Balaseviciute, J. Huguet-Pradell, J. Abril-Fornaguera, A. Gris-Oliver +14 more
2025Molecular Oncology3 citations Open access
Semantic Scholar
Cabozantinib enhances the efficacy and immune modulatory activity of anti-PD1 therapy in a syngeneic mouse model of hepatocellular carcinoma
R. Esteban-Fabró, Catherine E. Willoughby, M. Piqué-Gili, J. Peix +5 more
2020Journal of Hepatology3 citations Open access
Semantic Scholar
Histone methyl-transferase G9a inhibition boosts the efficacy of immune checkpoint inhibitors in experimental hepatocellular carcinoma
Elena Adán-Villaescusa, Borja Castelló-Uribe, I. Uriarte, Eva Santamaría +27 more
2026Cell Reports Medicine2 citations Open access
Semantic Scholar
TOP-507-YI Single-cell RNA sequencing-derived gene signatures reveal distinct response mechanisms to atezolizumab + bevacizumab in advanced hepatocellular carcinoma
S. Cappuyns, M. Piqué-Gili, R. Esteban-Fabró, G. Philips +28 more
2024Journal of Hepatology2 citations
Semantic Scholar

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J. Llovet×30
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C. Montironi×16
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D. Sia×14
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