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Barbara R Tschida · SciRah

Researcher profile · Semantic Scholar

Barbara R Tschida

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Barbara R Tschida — researcher profile on SciRah

h-index: 15
Works: 38
Citations: 1,027

Most-cited papers

Somatic CRISPR/Cas9-mediated tumour suppressor disruption enables versatile brain tumour modelling
Marc Zuckermann, V. Hovestadt, C. Knobbe-Thomsen, M. Zapatka +14 more
2015Nature Communications290 citations Open access
Semantic Scholar
Identification of Rtl1, a Retrotransposon-Derived Imprinted Gene, as a Novel Driver of Hepatocarcinogenesis
Jesse D. Riordan, V. Keng, Barbara R Tschida, T. Scheetz +8 more
2013PLoS Genetics88 citations Open access
Semantic Scholar
PTEN and NF1 inactivation in Schwann cells produces a severe phenotype in the peripheral nervous system that promotes the development and malignant progression of peripheral nerve sheath tumors
V. Keng, E. Rahrmann, A. Watson, Barbara R Tschida +6 more
2012Cancer Research86 citations Open access
Semantic Scholar
Modeling HBx induced hepatocellular carcinoma in mice using the Sleeping Beauty transposon system
V. Keng, Barbara R Tschida, Jason B. Bell, David A. Largaespada
2011Hepatology68 citations Open access
Semantic Scholar
mTORC1 Coordinates Protein Synthesis and Immunoproteasome Formation via PRAS40 to Prevent Accumulation of Protein Stress
Young S. Yun, Kwan Hyun Kim, Barbara R Tschida, Z. Sachs +8 more
2016Molecules and Cells65 citations Open access
Semantic Scholar
Gender bias occurrence of hepatocellular carcinoma in Poly7 molecular subclass is associated with EGFR
V. Keng, D. Sia, A. Sarver, Barbara R Tschida +13 more
2012Hepatology61 citations Open access
Semantic Scholar
Insertional mutagenesis identifies a STAT3/Arid1b/β-catenin pathway driving neurofibroma initiation
Jian-Qiang Wu, V. Keng, Deanna M. Patmore, Jed J. Kendall +19 more
2016Cell Reports59 citations Open access
Semantic Scholar
Sleeping Beauty insertional mutagenesis reveals important genetic drivers of central nervous system embryonal tumors.
Pauline J Beckmann, Jon D. Larson, Alex T. Larsson, Jason Ostergaard +29 more
2019Cancer Research46 citations Open access
Semantic Scholar
Conditional Inactivation of Pten with EGFR Overexpression in Schwann Cells Models Sporadic MPNST
V. Keng, A. Watson, E. Rahrmann, Hua Li +8 more
2012Sarcoma45 citations Open access
Semantic Scholar
Sleeping Beauty insertional mutagenesis in mice identifies drivers of steatosis-associated hepatic tumor
Barbara R Tschida, N. Temiz, Timothy P. Kuka, Lindsey A. Lee +16 more
2017Cancer Research40 citations Open access
Semantic Scholar
Chronic liver injury alters driver mutation profiles in hepatocellular carcinoma
Jesse D. Riordan, Charlotte R. Feddersen, Barbara R Tschida, P. Jackson +6 more
2018Hepatology36 citations Open access
Semantic Scholar
ZBTB20 regulates WNT/CTNNB1 signalling pathway by suppressing PPARG during hepatocellular carcinoma tumourigenesis
Jeffrey C. To, Amy P Chiu, Barbara R Tschida, L. Lo +10 more
2020JHEP Reports31 citations Open access
Semantic Scholar
HBx-K130M/V131I promotes liver cancer in transgenic mice via AKT/FOXO1 signaling pathway and arachidonic acid metabolism
Amy P Chiu, Barbara R Tschida, Tung-Ting Sham, L. Lo +10 more
2019Molecular Cancer Research31 citations Open access
Semantic Scholar
R‐spondin 2 Drives Liver Tumor Development in a Yes‐Associated Protein‐Dependent Manner
C. Conboy, Germán L Vélez-Reyes, Barbara R Tschida, Hsiangyu Hu +15 more
2019Hepatology Communications23 citations Open access
Semantic Scholar
Mouse Models of Cancer: Sleeping Beauty Transposons for Insertional Mutagenesis Screens and Reverse Genetic Studies
Barbara R Tschida, D. Largaespada, V. Keng
2014Seminars in Cell and Developmental Biology23 citations Open access
Semantic Scholar
Overexpression of HGF/MET axis along with p53 inhibition induces de novo glioma formation in mice
Yuan Qin, Anna Musket, Jian-Qun Kou, J. Preiszner +10 more
2020Neuro-Oncology Advances13 citations Open access
Semantic Scholar
Selumetinib normalizes Ras/MAPK signaling in clinically relevant neurofibromatosis type 1 minipig tissues in vivo
Sara H. Osum, Alex Coutts, D. Duerre, Barbara R Tschida +9 more
2021Neuro-Oncology Advances11 citations Open access
Semantic Scholar
Transposon mouse models to elucidate the genetic mechanisms of hepatitis B viral induced hepatocellular carcinoma.
Amy P Chiu, Barbara R Tschida, L. Lo, B. Moriarity +3 more
2015World Journal of Gastroenterology7 citations Open access
Semantic Scholar
Differential migration mechanics and immune responses of glioblastoma subtypes
Ghaidan A Shamsan, Chao J. Liu, B. Braman, Ru-Yi Li +14 more
2025bioRxiv1 citations Open access
Semantic Scholar
MODL-15. BRINGING PRECISION MEDICINE TO GLIOBLASTOMA PATIENTS BY MODELING MOLECULAR TUMOR SUBTYPES IN IMMUNOCOMPETENT SWINE FOR THERAPEUTIC AND BIOMARKER DEVELOPMENT
A. Watson, Derek M. Korpela, Nicholas Koes, Mandy E. Taisto +2 more
2022Neuro-Oncology1 citations Open access
Semantic Scholar
Abstract PR02: Somatic CRISPR/Cas9-mediated tumor suppressor disruption enables versatile brain tumor modeling
Marc Zuckermann, V. Hovestadt, C. Knobbe-Thomsen, M. Zapatka +14 more
20151 citations
Semantic Scholar
Abstract 354: Conditional inactivation of Pten and overexpression of EGFR in Schwann cells results in early high-grade peripheral nerve sheath tumor development.
V. Keng, A. Watson, E. Rahrmann, Hua Li +8 more
20131 citations
Semantic Scholar
Glioblastoma Subtypes Exhibit Distinct Migration Mechanics and Immune Responses
Ghaidan A Shamsan, Chao J. Liu, B. Braman, Ru-Yi Li +14 more
2026Cancer Research Communications0 citations Open access
Semantic Scholar
TMOD-03. A SWINE MODEL OF GLIOBLASTOMA INDUCED BY SOMATIC GENE MODIFICATION
Mandy E. Taisto, Barbara R Tschida, Alex Coutts, Jarryd M. Campbell +3 more
2021Neuro-Oncology0 citations Open access
Semantic Scholar
EXTH-08. MINIPIG MODELS OF NEUROFIBROMATOSIS TYPE 1 FOR THERAPEUTIC DEVELOPMENT
A. Watson, Sara H. Osum, Mandy E. Taisto, Barbara R Tschida +5 more
20200 citations Open access
Semantic Scholar
TAMI-28. DIFFERENTIAL MIGRATION MECHANICS AND IMMUNE RESPONSES OF GLIOMA SUBTYPES
Ghaidan A Shamsan, Chao Liu, B. Braman, S. Rathe +11 more
20200 citations Open access
Semantic Scholar
TMOD-20. A SWINE MODEL OF GLIOBLASTOMA INDUCED BY SOMATIC GENE MODIFICATION
Barbara R Tschida, D. Duerre, Mandy E. Taisto, A. Watson
20200 citations Open access
Semantic Scholar
TMOD-17. A SWINE MODEL OF GLIOBLASTOMA INDUCED BY SOMATIC GENE MODIFICATION
Barbara R Tschida, D. Duerre, Mandy E. Taisto, S. Solin +1 more
2019Neuro-Oncology0 citations Open access
Semantic Scholar
Abstract 5183: Using transposon elements to elucidate the genetic mechanisms of HCC-associated lung metastases
L. Lo, Amy P Chiu, Xiao-xiao Li, Barbara R Tschida +3 more
2018Tumor Biology0 citations Open access
Semantic Scholar
Title : Sleeping Beauty insertional mutagenesis reveals important genetic drivers of central nervous system embryonal tumors
Jon D. Larson, Alex T. Larsson, P. Jason, Ostergaard +32 more
20180 citations
Semantic Scholar
TMOD-44. HGF-AUTOCRINE ACTIVATION OF MET RECEPTOR TYROSINE KINASE INDUCES DE NOVO GLIOMA FORMATION IN MICE
Jian-Qun Kou, J. Preiszner, Jennifer Johnson, Barbara R Tschida +6 more
20170 citations Open access
Semantic Scholar
The Sleeping Beauty Transposon System For Forward And Reverse Genetic Studies Of Liver Cancer
Barbara R Tschida
20170 citations
Semantic Scholar
PCM-15SOMATIC CRISPR/Cas9-MEDIATED TUMOR SUPPRESSOR DISRUPTION ENABLES VERSATILE BRAIN TUMOR MODELING
Marc Zuckermann, V. Hovestadt, C. Knobbe-Thomsen, M. Zapatka +14 more
20160 citations Open access
Semantic Scholar
Abstract 63: A transposon-based forward genetic screen for steatosis-associated liver cancer drivers
Barbara R Tschida, N. Temiz, J. D. Yang, V. Keng +1 more
20160 citations
Semantic Scholar
Abstract 929: Identification of ZBTB20 as a novel oncogene associated with the gender bias occurrence of hepatocellular carcinoma
V. Keng, Barbara R Tschida, Timothy P. Kuka, B. Moriarity +2 more
20140 citations
Semantic Scholar
PM-21A REVERSE GENETIC SCREEN FOR DRIVERS OF GBM
Barbara R Tschida, A. Lowy, Courtney A. Marek, Thomas J. Ringstrom +6 more
20140 citations Open access
Semantic Scholar
PM-14MODELING GBM IN MICE USING THE CRISPR NUCLEASE SYSTEM TO FUNCTIONALLY VALIDATE NOVEL CANDIDATE DRIVER GENES AND TEST NEW THERAPIES
Brian Moriarity, Barbara R Tschida, D. Largaespada
20140 citations Open access
Semantic Scholar
Induction of Glioblastoma Multiforme and Gliomatosis Cerebri with a Sleeping Beauty gene transfer system, implications for T regulatory cell involvement during glioma formation.
D. Çağlayan, B. Moriarity, Barbara R Tschida, M. Kastemar +3 more
20120 citations
Semantic Scholar

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