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Balca R. Mardin · SciRah

Researcher profile · Semantic Scholar

Balca R. Mardin

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Balca R. Mardin — researcher profile on SciRah

h-index: 19
Works: 34
Citations: 1,854

Most-cited papers

Pan-cancer analysis of somatic copy number alterations implicates IRS4 and IGF2 in enhancer hijacking
J. Weischenfeldt, Taronish D. Dubash, Alexandros P. Drainas, Balca R. Mardin +28 more
2016Nature Genetics369 citations Open access
Semantic Scholar
Tandem fluorescent protein timers for in vivo analysis of protein dynamics
Anton Khmelinskii, P. Keller, Anna Bartosik, M. Meurer +9 more
2012Nature Biotechnology285 citations
Semantic Scholar
Components of the Hippo pathway cooperate with Nek2 kinase to regulate centrosome disjunction
Balca R. Mardin, C. Lange, Joanne E. Baxter, Tara Hardy +3 more
2010Nature Cell Biology179 citations Open access
Semantic Scholar
A cell-based model system links chromothripsis with hyperploidy
Balca R. Mardin, Alexandros P. Drainas, S. Waszak, J. Weischenfeldt +11 more
2015Molecular Systems Biology138 citations Open access
Semantic Scholar
Breaking the ties that bind: New advances in centrosome biology
Balca R. Mardin, E. Schiebel
2012Journal of Cell Biology128 citations Open access
Semantic Scholar
Separate to operate: control of centrosome positioning and separation
F. G. Agircan, E. Schiebel, Balca R. Mardin
2014Philosophical Transactions of the Royal Society B: Biological Sciences109 citations Open access
Semantic Scholar
Single-cell analysis of structural variations and complex rearrangements with tri-channel-processing
A. Sanders, S. Meiers, M. Ghareghani, D. Porubsky +19 more
2019Nature Biotechnology77 citations Open access
Semantic Scholar
Negative Selection and Chromosome Instability Induced by Mad2 Overexpression Delay Breast Cancer but Facilitate Oncogene-Independent Outgrowth
Konstantina Rowald, M. Mantovan, J. Passos, Christopher Buccitelli +4 more
2016Cell Reports77 citations Open access
Semantic Scholar
EGF Induced Centrosome Separation Promotes Mitotic Progression and Cell Survival
Balca R. Mardin, Mayumi Isokane, M. R. Cosenza, A. Krämer +3 more
2013Developmental Cell66 citations Open access
Semantic Scholar
Systems approaches identify the consequences of monosomy in somatic human cells
N. K. Chunduri, P. Menges, Xiaoxiao Zhang, A. Wieland +8 more
2021Nature Communications63 citations Open access
Semantic Scholar
Pan-cancer analysis distinguishes transcriptional changes of aneuploidy from proliferation
Christopher Buccitelli, L. Salgueiro, Konstantina Rowald, R. Sotillo +2 more
2017Genome Research56 citations Open access
Semantic Scholar
Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort
S. Waszak, P. Northcott, I. Buchhalter, G. Robinson +83 more
2018The Lancet Oncology47 citations Open access
Semantic Scholar
Identification of ZCCHC8 as fusion partner of ROS1 in a case of congenital glioblastoma multiforme with a t(6;12)(q21;q24.3)
Mariela C. Coccé, Balca R. Mardin, S. Bens, A. Stütz +6 more
2016Genes, Chromosomes and Cancer38 citations
Semantic Scholar
A scalable CRISPR/Cas9-based fluorescent reporter assay to study DNA double-strand break repair choice
Paris Roidos, Stephanie Sungalee, Salvatore Benfatto, Ozdemirhan Sercin +6 more
2020Nature Communications36 citations Open access
Semantic Scholar
Uncovering cancer vulnerabilities by machine learning prediction of synthetic lethality
Salvatore Benfatto, Ozdemirhan Sercin, F. Dejure, A. Abdollahi +2 more
2021Molecular Cancer33 citations Open access
Semantic Scholar
Immortalization capacity of HPV types is inversely related to chromosomal instability
Denise M. Schütze, O. Krijgsman, P. Snijders, B. Ylstra +10 more
2016OncoTarget30 citations Open access
Semantic Scholar
Genome-wide Screens Implicate Loss of Cullin Ring Ligase 3 in Persistent Proliferation and Genome Instability in TP53-Deficient Cells
Alexandros P. Drainas, R. Lambuta, I. Ivanova, Ozdemirhan Sercin +8 more
2020Cell Reports29 citations Open access
Semantic Scholar
High‐resolution transcriptomic and epigenetic profiling identifies novel regulators of COPD
U. Schwartz, Maria Llamazares-Prada, S. Pohl, M. Richter +30 more
2023EMBO Journal28 citations Open access
Semantic Scholar
Somatic structural variant formation is guided by and influences genome architecture
N. Sidiropoulos, Balca R. Mardin, F. G. Rodríguez-González, Ivan D. Bochkov +5 more
2021bioRxiv27 citations Open access
Semantic Scholar
The interplay of DNA repair context with target sequence predictably biases Cas9-generated mutations
Ananth Pallaseni, Elin Madli Peets, Gareth Girling, Luca Crepaldi +10 more
2023bioRxiv13 citations Open access
Semantic Scholar
A solid‐phase transfection platform for arrayed CRISPR screens
Ozdemirhan Sercin, S. Reither, Paris Roidos, N. Ballin +12 more
2019Molecular Systems Biology8 citations Open access
Semantic Scholar
Exploiting the metabolic dependencies of the broad amino acid transporter SLC6A14
F. Dejure, Joachim Butzer, R. Lindemann, Balca R. Mardin
2020OncoTarget6 citations Open access
Semantic Scholar
Systematic Identification of Determinants for Single-Strand Annealing-Mediated Deletion Formation in Saccharomyces cerevisiae
M. Segura-Wang, Megumi Onishi-Seebacher, A. Stütz, Balca R. Mardin +1 more
2017G3: Genes, Genomes, Genetics5 citations Open access
Semantic Scholar
Using large-scale genome variation cohorts to decipher the molecular mechanism of cancer.
Nina Habermann, Balca R. Mardin, Sergei Yakneen, J. Korbel
2016Comptes rendus. Biologies5 citations Open access
Semantic Scholar
Mechanistic insights into the monotherapy and combination potential of FEN1 inhibition in cancer therapy
E. Rajendra, Claudio A Lademann, Bethany Mason, Balca R. Mardin +23 more
2025Nucleic Acids Research4 citations
Semantic Scholar
Enzyme family-centred approach identifies helicases as recurrent hemizygous tumour suppressor genes
Karolin Voßgröne, F. Favero, Krushanka Kashyap, F. G. Rodríguez-González +5 more
2024bioRxiv1 citations Open access
Semantic Scholar
Hemizygous loss of helicases promotes genomic instability and cancer development
Karolin Voßgröne, F. Favero, Krushanka Kashyap, F. G. Rodríguez-González +5 more
2026Science Advances0 citations Open access
Semantic Scholar
Abstract 246: Discovery and mechanistic characterisation of the first oral bioavailable FEN1 inhibitor for treatment of HRD and EWS cancers and combination with various DDR inhibitors.
L. Burgdorf, Julien Lefranc, Lucy Armstrong, R. Boivin +33 more
2026Cancer Research0 citations
Semantic Scholar
Understanding tumor adaptations and resistance to MET inhibitors in MET-altered non-small cell lung cancer
M. Simard, E. Marin, S. García-Román, C. Aguado +24 more
2026Neoplasia0 citations Open access
Semantic Scholar
Abstract B064: Single-cell RNA sequencing reveals tumorigenic trajectories of mismatch repair deficient cells
Alexandra C. Vítor, S. Benfatto, F. Zenke, Sebastian M. Waszak +1 more
2023Molecular Cancer Therapeutics0 citations
Semantic Scholar
High-resolution transcriptomic and epigenetic profiling identifies novel regulators of COPD phenotypes in human lung fibroblasts
U. Schwartz, M. L. Prada, S. Pohl, M. Richter +27 more
2022bioRxiv0 citations Open access
Semantic Scholar
Single cell tri-channel-processing reveals structural variation landscapes and complex rearrangement processes
A. Sanders, S. Meiers, M. Ghareghani, D. Porubsky +17 more
2019bioRxiv0 citations Open access
Semantic Scholar
Abstract 2893: IGF2 is essential for tumor initiating cell activity in human colorectal cancer
Taronish D. Dubash, Christine Siegl, S. Dieter, J. Weischenfeldt +10 more
20170 citations
Semantic Scholar
jectories of genetics , 150 years after Mendel / Trajectoires de la génétique , 150 ans après Mendel ing large-scale genome variation cohorts to decipher the olecular mechanism of cancer de à grande échelle de variations génétiques pour déchiffrer les
Trabelsi M, Ni, Balca R. Mardin, Sergei Yakneen +1 more
20160 citations
Semantic Scholar

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J. Korbel×13
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A. Stütz×8
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J. Weischenfeldt×7
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Theocharis Efthymiopoulos×3

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