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Taronish D. Dubash · SciRah

Researcher profile · Semantic Scholar

Taronish D. Dubash

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Taronish D. Dubash — researcher profile on SciRah

h-index: 20
Works: 66
Citations: 2,233

Most-cited papers

Pan-cancer analysis of somatic copy number alterations implicates IRS4 and IGF2 in enhancer hijacking
J. Weischenfeldt, Taronish D. Dubash, Alexandros P. Drainas, Balca R. Mardin +28 more
2016Nature Genetics369 citations Open access
Semantic Scholar
Wnt secretion is required to maintain high levels of Wnt activity in colon cancer cells
O. Voloshanenko, G. Erdmann, Taronish D. Dubash, I. Augustin +13 more
2013Nature Communications244 citations Open access
Semantic Scholar
Visualizing engrafted human cancer and therapy responses in immunodeficient zebrafish
Chuan Yan, D. Brunson, Qin Tang, Daniel Do +24 more
2019Cell223 citations Open access
Semantic Scholar
The lipogenic regulator SREBF2 induces Transferrin in circulating melanoma cells and suppresses ferroptosis
Xin Hong, W. Roh, R. Sullivan, Keith H. K. Wong +25 more
2020Cancer Discovery204 citations Open access
Semantic Scholar
Combination Olaparib and Temozolomide in Relapsed Small Cell Lung Cancer
A. Farago, B. Yeap, Marcello Stanzione, Yin P. Hung +21 more
2019Cancer Discovery202 citations Open access
Semantic Scholar
Ultrahigh-throughput magnetic sorting of large blood volumes for epitope-agnostic isolation of circulating tumor cells
A. Mishra, Taronish D. Dubash, J. Edd, Michelle K Jewett +10 more
2020Proceedings of the National Academy of Sciences of the United States of America137 citations Open access
Semantic Scholar
A digital RNA signature of Circulating Tumor Cells predicting early therapeutic response in localized and metastatic breast cancer
T. Kwan, A. Bardia, L. Spring, A. Giobbie-Hurder +14 more
2018Cancer Discovery89 citations Open access
Semantic Scholar
DrugMap: A quantitative pan-cancer analysis of cysteine ligandability
Mariko Takahashi, H. Chong, Siwen Zhang, Tzu-yi Yang +67 more
2024Cell74 citations Open access
Semantic Scholar
TGF-β in the microenvironment induces a physiologically occurring immune-suppressive senescent state
Satoru Matsuda, Ajinkya Revandkar, Taronish D. Dubash, Arvind Ravi +15 more
2023Cell Reports73 citations Open access
Semantic Scholar
NR4A1 regulates expression of immediate early genes, suppressing replication stress in cancer
Hong-Shan Guo, Gabriel Golczer, B. Wittner, Adam Langenbucher +24 more
2021Molecules and Cells61 citations Open access
Semantic Scholar
SETD1A protects from senescence through regulation of the mitotic gene expression program
K. Tajima, S. Matsuda, Toshifumi Yae, B. Drapkin +13 more
2019Nature Communications59 citations Open access
Semantic Scholar
Microfluidic concentration and separation of circulating tumor cell clusters from large blood volumes
J. Edd, A. Mishra, Taronish D. Dubash, Stefan Herrera +13 more
2020Lab on a Chip58 citations Open access
Semantic Scholar
Asymmetric Centriole Numbers at Spindle Poles Cause Chromosome Missegregation in Cancer.
M. R. Cosenza, A. Cazzola, Annik Rossberg, N. Schieber +11 more
2017Cell Reports52 citations Open access
Semantic Scholar
Tumor cell-based liquid biopsy using high-throughput microfluidic enrichment of entire leukapheresis product
A. Mishra, Shih-Bo Huang, Taronish D. Dubash, Risa Burr +29 more
2025Nature Communications43 citations Open access
Semantic Scholar
Succession of transiently active tumor‐initiating cell clones in human pancreatic cancer xenografts
C. Ball, F. Oppel, K. R. Ehrenberg, Taronish D. Dubash +16 more
2017EMBO Molecular Medicine40 citations Open access
Semantic Scholar
Patient‐derived xenografts of gastrointestinal cancers are susceptible to rapid and delayed B‐lymphoproliferation
S. Dieter, Klara M. Giessler, M. Kriegsmann, Taronish D. Dubash +23 more
2017International Journal of Cancer31 citations Open access
Semantic Scholar
Blood-based monitoring identifies acquired and targetable driver HER2 mutations in endocrine-resistant metastatic breast cancer
A. Medford, Taronish D. Dubash, D. Juric, L. Spring +18 more
2019npj Precision Oncology30 citations Open access
Semantic Scholar
Genetic subclone architecture of tumor clone-initiating cells in colorectal cancer
Klara M. Giessler, K. Kleinheinz, D. Hübschmann, G. Balasubramanian +21 more
2017Journal of Experimental Medicine30 citations Open access
Semantic Scholar
The notch target gene HEYL modulates metastasis forming capacity of colorectal cancer patient-derived spheroid cells in vivo
Sarah Weber, Sebastian E. Koschade, Christopher M. Hoffmann, Taronish D. Dubash +5 more
2019BMC Cancer27 citations Open access
Semantic Scholar
Developmental mosaicism underlying EGFR-mutant lung cancer presenting with multiple primary tumors
Risa Burr, I. Leshchiner, Christina L Costantino, Martin Blohmer +22 more
2024Nature Cancer23 citations Open access
Semantic Scholar
DrugMap: A quantitative pan-cancer analysis of cysteine ligandability
Mariko Takahashi, H. Chong, Siwen Zhang, Matthew J Lazarov +65 more
2023bioRxiv21 citations Open access
Semantic Scholar
Evaluation of endocrine resistance using ESR1 genotyping of circulating tumor cells and plasma DNA
T. Sundaresan, Taronish D. Dubash, Zong-Li Zheng, A. Bardia +10 more
2021Breast Cancer Research and Treatment21 citations Open access
Semantic Scholar
Identification of somatically acquired BRCA1/2 mutations by cfDNA analysis in patients with metastatic breast cance
N. Vidula, Taronish D. Dubash, Michael S. Lawrence, A. Simoneau +25 more
2020Clinical Cancer Research19 citations Open access
Semantic Scholar
In-flow measurement of cell-cell adhesion using oscillatory inertial microfluidics
B. Mutlu, Taronish D. Dubash, C. Dietsche, A. Mishra +6 more
2020Lab on a Chip15 citations Open access
Semantic Scholar
Systematic Generation of Patient-Derived Tumor Models in Pancreatic Cancer
K. R. Ehrenberg, Jian-Peng Gao, F. Oppel, S. Frank +18 more
2019Cells14 citations Open access
Semantic Scholar
A Gene Panel Associated With Abemaciclib Utility in ESR1-Mutated Breast Cancer After Prior Cyclin-Dependent Kinase 4/6-Inhibitor Progression
Jamie O. Brett, Taronish D. Dubash, Gabriela N. Johnson, A. Niemierko +28 more
2023JCO Precision Oncology13 citations Open access
Semantic Scholar
Phenotypic differentiation does not affect tumorigenicity of primary human colon cancer initiating cells.
Taronish D. Dubash, Christopher M. Hoffmann, F. Oppel, Klara M. Giessler +13 more
2016Cancer Letters13 citations
Semantic Scholar
Regulation of GAD65 expression by SMAR1 and p53 upon Streptozotocin treatment
S. Singh, Varsheish Raina, P. L. Chavali, Taronish D. Dubash +3 more
2012BMC Molecular Biology13 citations Open access
Semantic Scholar
Tumor cell-based liquid biopsy using high-throughput microfluidic enrichment of entire leukapheresis product
A. Mishra, Shih-Bo Huang, Taronish D. Dubash, Risa Burr +29 more
2024bioRxiv12 citations Open access
Semantic Scholar
Isolation of Yeasts from Various Food Products and Detection of Killer Toxin Activity In vitro
Taronish D. Dubash, Sumit Gupta, P. Prakash, I. Bairy
20108 citations Open access
Semantic Scholar
Modeling the novel SERD elacestrant in cultured fulvestrant-refractory HR-positive breast circulating tumor cells
Taronish D. Dubash, A. Bardia, Brian Chirn, B. Reeves +19 more
2023Breast Cancer Research and Treatment5 citations Open access
Semantic Scholar
CDKN1B (p27/kip1) enhances drug-tolerant persister CTCs by restricting polyploidy following mitotic inhibitors
Elad Horwitz, Taronish D. Dubash, A. Szabolcs, B. Wittner +16 more
2024bioRxiv4 citations Open access
Semantic Scholar
Differential kinase activity across prostate tumor compartments defines sensitivity to target inhibition
N. Karabacak, Yu Zheng, Taronish D. Dubash, Risa Burr +20 more
2022Cancer Research4 citations Open access
Semantic Scholar
Safety and antitumour activity of ipatasertib combined with endocrine therapy and a CDK4/6 inhibitor in HR+/HER2- metastatic breast cancer (TAKTIC): a single-centre, open-label, phase 1b trial.
S. Wander, Maxwell R. Lloyd, J. Keenan, Elizabeth C. Scott +26 more
2026The Lancet Oncology2 citations
Semantic Scholar
Abstract PD2-03: Association between co-existing genomic alterations and abemaciclib benefit in patients with metastatic hormone receptor-positive breast cancer with ESR1 mutations following disease progression on prior endocrine therapy plus palbociclib or ribociclib
Jamie O. Brett, Taronish D. Dubash, A. Niemierko, V. Mariotti +20 more
2022Cancer Research2 citations
Semantic Scholar
Biocontrol of yeast spoilage in selected food and beverages by yeast mycocin
P. Valsaraj, Taronish D. Dubash, P. Prakash
20122 citations
Semantic Scholar
Abstract B099: Targeting Non Small Cell Lung Cancer EGFR-Mutant and EGFR-Inhibitor resistant cell lines by ferroptosis induction: A potential therapeutic approach
Taronish D. Dubash, Maria Cristina Munteanu, Cristian Nunez, Shrouq I. Farah +5 more
2023Molecular Cancer Therapeutics1 citations
Semantic Scholar
Abstract P1-18-22: AKT inhibition in combination with endocrine therapy and a CDK4/6 inhibitor (CDK4/6i) in patients with hormone receptor positive (HR+)/HER2 negative metastatic breast cancer (MBC) and prior CDK4/6i exposure: A translational investigation
S. Wander, D. Micalizzi, Taronish D. Dubash, D. Juric +15 more
2022Cancer Research1 citations
Semantic Scholar
Abstract P4-01-06: Elacestrant (RAD1901) inhibits growth of ex vivo cultured circulating tumor cells derived from hormone receptor-positive metastatic breast cancer (mBC) patients including those harboring ESR1 mutations
Taronish D. Dubash, A. Bardia, B. Reeves, Brian Chirn +9 more
2020Poster Session Abstracts1 citations
Semantic Scholar
Abstract LB152: ACR-368 synergizes with PD-L1 blockade by coordinated activation of adaptive and innate immunity pathways to achieve robust anti-tumor efficacy
A. Elbakry, Taronish D. Dubash, J. Baddour-Sousounis, Jessica Hopkins +25 more
2026Cancer Research0 citations
Semantic Scholar
Abstract A082: AP3-guided biological SAR enables discovery of ACR-2316, a novel clinical-stage WEE1/PKMYT1 inhibitor designed for CDK1/2 and PLK1 pathway activation
Lei Shi, Marc Isaksson, Ahmed Youssef, Valentina Siino +29 more
2026Clinical Cancer Research0 citations
Semantic Scholar
Abstract 239: Potent synergy between CHK1/2 inhibitor ACR-368 and the ADC payload topoisomerase I inhibitor: Rationale for ADC + ACR-368 combination therapy.
Portia Lombardo, Ahmed Youssef, Mohamed Eldeeb, Nina Lipjankić +27 more
2026Cancer Research0 citations
Semantic Scholar
Genomic biomarkers of ipatasertib response in patients with hormone receptor-positive metastatic breast cancer
Maxwell R. Lloyd, Z. Bagheri, Elizabeth C. Scott, Geoffrey G. Fell +25 more
2026npj Breast Cancer0 citations Open access
Semantic Scholar
Abstract 3789: Treatment with ACR-2316, a potential first- and best-in-class WEE1/PKMYT1 inhibitor, combined with anti-PD-L1 induces complete tumor regression with durable immune memory
Taronish D. Dubash, J. Baddour-Sousounis, A. Elbakry, Jessica Hopkins +27 more
2026Cancer Research0 citations
Semantic Scholar
Abstract A097: Global pharmacodynamic effects uncovered with AP3 phosphoproteomic profiling of novel WEE1/PKMYT1 inhibitor ACR-2316 reveals the critical importance of PLK1 for ACR-2316’s superior preclinical activity and differentiated mechanism of action
Subodh Kumar, J. Baddour-Sousounis, Y. Liu, Mohamed Eldeeb +31 more
2025Molecular Cancer Therapeutics0 citations
Semantic Scholar
Abstract A017: High-throughput microfluidic enrichment of circulating tumor cells from entire diagnostic leukapheresis for comprehensive liquid biopsy
A. Mishra, Shih-Bo Huang, Taronish D. Dubash, Risa Burr +29 more
2024Clinical Cancer Research0 citations
Semantic Scholar
Abstract 771: Mechanisms of genetic predisposition to multifocal lung cancer
Risa Burr, I. Leshchiner, C. L. Costantino, Martin Blohmer +21 more
2023Cancer Research0 citations
Semantic Scholar
Germline mutations and developmental mosaicism underlying EGFR-mutant lung cancer
Risa Burr, I. Leshchiner, Christina L Costantino, Martin Blohmer +22 more
2023medRxiv0 citations Open access
Semantic Scholar
Abstract 1668: Targeting drug-induced tolerant & resistant cell populations by novel ferroptosis inducer
Taronish D. Dubash, M. Munteanu, Shrouq I. Farah, Cristian Nunez +4 more
2023Cancer Research0 citations Open access
Semantic Scholar
Abstract CT073: Efficacy of novel oral SERD elacestrant in fulvestrant-refractory hormone receptor-positive (HR+) breast cancer: a translational investigation
Taronish D. Dubash, A. Bardia, Brian Chirn, B. Reeves +18 more
2023Cancer Research0 citations
Semantic Scholar

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