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N. Keep · SciRah

Researcher profile · Semantic Scholar

N. Keep

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N. Keep — researcher profile on SciRah

h-index: 36
Works: 112
Citations: 4,759

Most-cited papers

The CCP4 suite: integrative software for macromolecular crystallography
J. Agirre, Mihaela Atanasova, Haroldas Bagdonas, C. Ballard +90 more
2023Acta Crystallographica Section D: Structural Biology520 citations Open access
Semantic Scholar
Crystal structures of alpha-crystallin domain dimers of alphaB-crystallin and Hsp20.
C. Bagnéris, O. Bateman, C. Naylor, N. Cronin +3 more
2009Journal of Molecular Biology277 citations Open access
Semantic Scholar
Human BRCA1-BARD1 Ubiquitin ligase activity counters chromatin barriers to DNA resection
R. Densham, Alexander J. Garvin, Helen R. Stone, J. Strachan +11 more
2016Nature Structural &Molecular Biology273 citations Open access
Semantic Scholar
The GDP-GTP Exchange Factor Collybistin: An Essential Determinant of Neuronal Gephyrin Clustering
K. Harvey, Ian Duguid, M. Alldred, Sarah E. Beatty +10 more
2004Journal of Neuroscience269 citations Open access
Semantic Scholar
Characterisation of Bombyx mori Odorant-binding proteins reveals that a general odorant-binding protein discriminates between sex pheromone components.
Jing-Jiang Zhou, G. Robertson, Xiao-Li He, S. Dufour +4 more
2009Journal of Molecular Biology258 citations Open access
Semantic Scholar
The structure of the N-terminal actin-binding domain of human dystrophin and how mutations in this domain may cause Duchenne or Becker muscular dystrophy.
Fiona L. M. Norwood, A. Sutherland-Smith, N. Keep, J. Kendrick-Jones
2000Structure177 citations Open access
Semantic Scholar
Cell wall peptidoglycan in Mycobacterium tuberculosis: An Achilles’ heel for the TB-causing pathogen
Arundhati Maitra, T. Munshi, J. Healy, Liam Martin +3 more
2019FEMS Microbiology Reviews168 citations Open access
Semantic Scholar
The structure of a resuscitation-promoting factor domain from Mycobacterium tuberculosis shows homology to lysozymes
M. Cohen-Gonsaud, P. Barthe, C. Bagnéris, B. Henderson +3 more
2005Nature Structural &Molecular Biology163 citations Open access
Semantic Scholar
Wake up! Peptidoglycan lysis and bacterial non-growth states.
N. Keep, J. Ward, M. Cohen-Gonsaud, B. Henderson
2006Trends in Microbiology152 citations
Semantic Scholar
Crystal Structure of R120G Disease Mutant of Human αB-Crystallin Domain Dimer Shows Closure of a Groove
A. R. Clark, C. Naylor, C. Bagnéris, N. Keep +1 more
2011Journal of Molecular Biology115 citations Open access
Semantic Scholar
Genetic analysis of BRCA1 ubiquitin ligase activity and its relationship to breast cancer susceptibility.
Joanna R. Morris, L. Pangon, C. Boutell, T. Katagiri +2 more
2006Human Molecular Genetics111 citations Open access
Semantic Scholar
Dodecameric Structure of the Small Heat Shock Protein Acr1 from Mycobacterium tuberculosis*
C. Kennaway, J. Benesch, U. Gohlke, Lu-Chun Wang +4 more
2005Journal of Biological Chemistry110 citations Open access
Semantic Scholar
Crystal structure of the actin-binding region of utrophin reveals a head-to-tail dimer.
N. Keep, Steven J. Winder, C. Moores, S. Walke +2 more
1999Structure106 citations Open access
Semantic Scholar
The 2.7 A crystal structure of the activated FERM domain of moesin: an analysis of structural changes on activation.
Simon Edwards, N. Keep
2001Biochemistry95 citations
Semantic Scholar
Characterisation of ATP-Dependent Mur Ligases Involved in the Biogenesis of Cell Wall Peptidoglycan in Mycobacterium tuberculosis
T. Munshi, Antima Gupta, D. Evangelopoulos, J. Guzman +3 more
2013PLoS ONE86 citations Open access
Semantic Scholar
Resuscitation-promoting factors possess a lysozyme-like domain.
M. Cohen-Gonsaud, N. Keep, A. Davies, J. Ward +2 more
2004TIBS -Trends in Biochemical Sciences. Regular ed81 citations Open access
Semantic Scholar
Structure of the utrophin actin-binding domain bound to F-actin reveals binding by an induced fit mechanism.
C. Moores, N. Keep, J. Kendrick-Jones
2000Journal of Molecular Biology77 citations
Semantic Scholar
Pictet-Spenglerases in alkaloid biosynthesis: Future applications in biocatalysis.
R. Roddan, J. Ward, N. Keep, H. Hailes
2020Current Opinion in Chemical Biology75 citations Open access
Semantic Scholar
Crystal Structures and Binding Dynamics of Odorant-Binding Protein 3 from two aphid species Megoura viciae and Nasonovia ribisnigri
T. Northey, H. Venthur, F. De Biasio, François-Xavier Chauviac +7 more
2016Scientific Reports73 citations Open access
Semantic Scholar
‘Dopamine-first’ mechanism enables the rational engineering of the norcoclaurine synthase aldehyde activity profile
B. Lichman, Markus C. Gershater, E. Lamming, T. Pesnot +4 more
2015The FEBS Journal72 citations Open access
Semantic Scholar
The X-ray Crystal Structure and Putative Ligand-derived Peptide Binding Properties of γ-Aminobutyric Acid Receptor Type A Receptor-associated Protein*
D. Knight, Richard J. Harris, M. McAlister, J. Phelan +4 more
2002Journal of Biological Chemistry72 citations Open access
Semantic Scholar
Dbl3 drives Cdc42 signaling at the apical margin to regulate junction position and apical differentiation
C. Zihni, P. Munro, A. Elbediwy, N. Keep +4 more
2014Journal of Cell Biology67 citations Open access
Semantic Scholar
ATP-dependent MurE ligase in Mycobacterium tuberculosis: biochemical and structural characterisation.
Chandrakala Basavannacharya, G. Robertson, T. Munshi, N. Keep +1 more
2010Tuberculosis60 citations
Semantic Scholar
Identification of Residues Required for the Interaction of BARD1 with BRCA1*
Joanna R. Morris, N. Keep, E. Solomon
2002Journal of Biological Chemistry49 citations Open access
Semantic Scholar
Structural Evidence for the Dopamine-First Mechanism of Norcoclaurine Synthase
B. Lichman, A. Sula, T. Pesnot, H. Hailes +2 more
2017Biochemistry45 citations Open access
Semantic Scholar
Bacterial resuscitation factors: revival of viable but non-culturable bacteria
N. Keep, John M. Ward, G. Robertson, M. Cohen-Gonsaud +1 more
2006Cellular and Molecular Life Sciences (CMLS)45 citations Open access
Semantic Scholar
Mapping the binding site for the GTP-binding protein Rac-1 on its inhibitor RhoGDI-1.
Lu-Yun Lian, I. Barsukov, A. Golovanov, Dawn Hawkins +5 more
2000Structure45 citations Open access
Semantic Scholar
Terminal Regions Confer Plasticity to the Tetrameric Assembly of Human HspB2 and HspB3
A. R. Clark, W. V. Vree Egberts, Frances D. L. Kondrat, Gillian R. Hilton +7 more
2018Journal of Molecular Biology44 citations Open access
Semantic Scholar
Corrigendum to Crystal Structures of α-Crystallin Domain Dimers of αB-Crystallin and Hsp20
C. Bagnéris, O. Bateman, C. Naylor, N. Cronin +3 more
200943 citations Open access
Semantic Scholar
Crystal structures of the human Dysferlin inner DysF domain
A. Sula, A. Cole, C. Yeats, C. Orengo +1 more
2014BMC Structural Biology39 citations Open access
Semantic Scholar
Solution structure of the inner DysF domain of myoferlin and implications for limb girdle muscular dystrophy type 2b.
P. Patel, Richard J. Harris, S. Geddes, E. Strehle +5 more
2008Journal of Molecular Biology39 citations Open access
Semantic Scholar
Essential residues for the enzyme activity of ATP-dependent MurE ligase from Mycobacterium tuberculosis
Chandrakala Basavannacharya, P. Moody, T. Munshi, N. Cronin +2 more
2010Protein & Cell38 citations Open access
Semantic Scholar
Acceptance and Kinetic Resolution of α-Methyl-Substituted Aldehydes by Norcoclaurine Synthases
R. Roddan, G. Gygli, A. Sula, D. Méndez-Sánchez +4 more
2019ACS Catalysis34 citations Open access
Semantic Scholar
Crystal structure of the core domain of RhoE/Rnd3: a constitutively activated small G protein.
Halina Garavini, K. Riento, J. Phelan, M. McAlister +2 more
2002Biochemistry32 citations
Semantic Scholar
Structural comparison of actin binding in utrophin and dystrophin
N. Keep
2000Neurological Sciences25 citations
Semantic Scholar
Crystal Structure of Reduced MsAcg, a Putative Nitroreductase from Mycobacterium smegmatis and a Close Homologue of Mycobacterium tuberculosis Acg
François-Xavier Chauviac, M. Bommer, Jun Yan, G. Parkin +5 more
2012Journal of Biological Chemistry23 citations Open access
Semantic Scholar
N-terminus-mediated dimerization of ROCK-I is required for RhoE binding and actin reorganization.
R. Garg, K. Riento, N. Keep, Jonathan D. H. Morris +1 more
2008Biochemical Journal23 citations Open access
Semantic Scholar
Chemoenzymatic Cascades toward Methylated Tetrahydroprotoberberine and Protoberberine Alkaloids.
R. Roddan, Fabiana Subrizi, J. Broomfield, John M. Ward +2 more
2021Organic Letters22 citations Open access
Semantic Scholar
Single step syntheses of (1S)-aryl-tetrahydroisoquinolines by norcoclaurine synthases
R. Roddan, A. Sula, D. Méndez-Sánchez, Fabiana Subrizi +7 more
2020Communications Chemistry17 citations Open access
Semantic Scholar
The RpfC (Rv1884) atomic structure shows high structural conservation within the resuscitation-promoting factor catalytic domain
François-Xavier Chauviac, G. Robertson, D. H. Quay, C. Bagnéris +5 more
2014Acta Crystallographica Section F Structural Biology Communications15 citations Open access
Semantic Scholar
Characterization of the MurT/GatD complex in Mycobacterium tuberculosis towards validating a novel anti-tubercular drug target
Arundhati Maitra, Syamasundari Nukala, R. Dickman, Liam Martin +7 more
2021JAC-Antimicrobial Resistance13 citations Open access
Semantic Scholar
Proteomics study reveals cross-talk between Rho guanidine nucleotide dissociation inhibitor 1 post-translational modifications in epidermal growth factor stimulated fibroblasts.
I. Guerrera, N. Keep, J. Godovac-Zimmermann
2007Journal of Proteome Research13 citations
Semantic Scholar
Genetic analysis of BRCA 1 ubiquitin ligase activity and its relationship to breast cancer susceptibility
Joanna R. Morris, L. Pangon, C. Boutell, T. Katagiri +2 more
200612 citations
Semantic Scholar
Structure of the stationary phase survival protein YuiC from B.subtilis
D. H. Quay, A. Cole, A. Cryar, K. Thalassinos +3 more
2015BMC Structural Biology11 citations Open access
Semantic Scholar
Letter to the Editor: 1H, 15N, and 13C chemical shift assignments of the resuscitation promoting factor domain of Rv1009 from Mycobacterium tuberculosis
M. Cohen-Gonsaud, P. Barthe, F. Pommier, Richard J. Harris +3 more
200411 citations
Semantic Scholar
Critical Role of a Sheath Phosphorylation Site On the Assembly and Function of an Atypical Type VI Secretion System*
Jason Ziveri, C. Chhuon, A. Jamet, Héloïse Rytter +9 more
2019Molecular & Cellular Proteomics10 citations Open access
Semantic Scholar
Human BRCA1-BARD1 Ubiquitin ligase activity counters chromatin barriers to DNA resection
R. Densham, Alexander J. Garvin, Helen R. Stone, Joanna Strachan +14 more
20176 citations
Semantic Scholar
Characterization of an oxidoreductase from the arylamine N‐acetyltransferase operon in Mycobacterium smegmatis
D. Evangelopoulos, N. Cronin, T. Daviter, E. Sim +2 more
2011The FEBS Journal5 citations Open access
Semantic Scholar
(1)H, (15)N, and (13)C chemical shift assignments of the resuscitation promoting factor domain of Rv1009 from Mycobacterium tuberculosis.
M. Cohen-Gonsaud, P. Barthe, F. Pommier, Richard J. Harris +3 more
2004Journal of Biomolecular NMR5 citations
Semantic Scholar
Letter to the Editor: Backbone 1H, 13C, and 15N resonance assignments for a 14 kD protein, GABAA receptor associated protein (GABARAP)
Richard J. Harris, M. McAlister, A. Sankar, J. Phelan +3 more
20015 citations
Semantic Scholar

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