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T. Pesnot · SciRah

Researcher profile · Semantic Scholar

T. Pesnot

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T. Pesnot — researcher profile on SciRah

h-index: 17
Works: 33
Citations: 911

Most-cited papers

A survey of chemical methods for sugar-nucleotide synthesis.
Gerd K. Wagner, T. Pesnot, R. Field
2009Natural product reports (Print)138 citations
Semantic Scholar
Glycosyltransferases and their Assays
Gerd K. Wagner, T. Pesnot
2010ChemBioChem92 citations
Semantic Scholar
Phosphate mediated biomimetic synthesis of tetrahydroisoquinoline alkaloids.
T. Pesnot, Markus C. Gershater, J. Ward, H. Hailes
2011Chemical Communications87 citations
Semantic Scholar
The Catalytic Potential of Coptis japonica NCS2 Revealed – Development and Utilisation of a Fluorescamine‐Based Assay
T. Pesnot, Markus C. Gershater, J. Ward, H. Hailes
201278 citations
Semantic Scholar
‘Dopamine-first’ mechanism enables the rational engineering of the norcoclaurine synthase aldehyde activity profile
B. Lichman, Markus C. Gershater, E. Lamming, T. Pesnot +4 more
2015The FEBS Journal72 citations Open access
Semantic Scholar
Structural and mechanistic basis for a novel mode of glycosyltransferase inhibition
T. Pesnot, R. Jørgensen, M. Palcic, Gerd K. Wagner
2010Nature Chemical Biology72 citations Open access
Semantic Scholar
One-pot triangular chemoenzymatic cascades for the syntheses of chiral alkaloids from dopamine
B. Lichman, E. Lamming, T. Pesnot, J. M. Smith +2 more
201557 citations Open access
Semantic Scholar
Novel derivatives of UDP-glucose: concise synthesis and fluorescent properties.
T. Pesnot, Gerd K. Wagner
2008Organic and biomolecular chemistry48 citations
Semantic Scholar
Structural Evidence for the Dopamine-First Mechanism of Norcoclaurine Synthase
B. Lichman, A. Sula, T. Pesnot, H. Hailes +2 more
2017Biochemistry45 citations Open access
Semantic Scholar
Inhibition of galactosyltransferases by a novel class of donor analogues.
Karine Descroix, T. Pesnot, Yayoi Yoshimura, Sebastian S. Gehrke +3 more
2012Journal of Medicinal Chemistry38 citations Open access
Semantic Scholar
2- and 3-substituted imidazo[1,2-a]pyrazines as inhibitors of bacterial type IV secretion
James R. Sayer, K. Walldén, T. Pesnot, Frederick Campbell +8 more
2014Bioorganic & Medicinal Chemistry33 citations Open access
Semantic Scholar
Tetrahydroisoquinolines affect the whole-cell phenotype of Mycobacterium tuberculosis by inhibiting the ATP-dependent MurE ligase
J. Guzman, T. Pesnot, Diana Barrera, Heledd Davies +14 more
2015Journal of Antimicrobial Chemotherapy30 citations Open access
Semantic Scholar
Enzymatic synthesis of nucleobase-modified UDP-sugars: scope and limitations
Ben A Wagstaff, M. Rejžek, T. Pesnot, L. Tedaldi +5 more
2015Carbohydrate Research24 citations Open access
Semantic Scholar
Two-step synthesis of novel, bioactive derivatives of the ubiquitous cofactor nicotinamide adenine dinucleotide (NAD).
T. Pesnot, J. Kempter, Jörg Schemies, G. Pergolizzi +5 more
2011Journal of Medicinal Chemistry20 citations Open access
Semantic Scholar
A Novel Fluorescent Probe for Retaining Galactosyltransferases
T. Pesnot, M. Palcic, Gerd K. Wagner
2010ChemBioChem19 citations
Semantic Scholar
Base-modified Donor Analogues Reveal Novel Dynamic Features of a Glycosyltransferase
R. Jørgensen, T. Pesnot, Ho-Jun Lee, M. Palcic +1 more
2013Journal of Biological Chemistry18 citations Open access
Semantic Scholar
Exploring the role of the 5-substituent for the intrinsic fluorescence of 5-aryl and 5-heteroaryl uracil nucleotides: a systematic study.
T. Pesnot, L. Tedaldi, P. Jambrina, E. Rosta +1 more
2013Organic and biomolecular chemistry17 citations
Semantic Scholar
Novel UDP-GalNAc Derivative Structures Provide Insight into the Donor Specificity of Human Blood Group Glycosyltransferase
Gerd K. Wagner, T. Pesnot, M. Palcic, R. Jørgensen
2015Journal of Biological Chemistry9 citations Open access
Semantic Scholar
One–Pot Phosphate-Mediated Synthesis of Novel 1,3,5-Trisubstituted Pyridinium Salts: A New Family of S. aureus Inhibitors
T. Pesnot, Markus C. Gershater, M. Edwards, J. Ward +1 more
2017Molecules7 citations Open access
Semantic Scholar
Novel C-7 carbon substituted fourth generation fluoroquinolones targeting N. Gonorrhoeae infections.
R. Kirk, Mark S. Betson, M. Bingham, P. Doyle +7 more
2020Bioorganic & Medicinal Chemistry Letters3 citations Open access
Semantic Scholar
5-Phenyluridine trihydrate.
T. Pesnot, D. Hughes, Gerd K. Wagner
2008Acta Crystallographica Section C: Crystal Structure Communications2 citations
Semantic Scholar
A Survey of Chemical Methods for Sugar‐Nucleoside Synthesis
Gerd K. Wagner, T. Pesnot, R. Field
20091 citations
Semantic Scholar
5-Phenyluridine•3H2O
T. Pesnot, D. Hughes, Gerd K. Wagner
20081 citations
Semantic Scholar
Kinetic screening using grating-coupled interferometry (GCI) – highly sensitive biosensor-based assays enable the identification of weak fragment hits across a diverse set of challenging targets
M. Janczuk-Richter, E. A. Fitzgerald, D. Cederfeldt, B. A. Lund +4 more
2026Acta Crystallographica Section A: Foundations and Advances0 citations
Semantic Scholar
Abstract 419: The development of BRPF1 degraders as a potential treatment for acute myeloid leukemia
Danielle J. Glynn, R. Crampton, T. Pesnot, Andrew Scott +10 more
2022Cancer Research0 citations
Semantic Scholar
Abstract 2751: Development of a specific Wee-1 inhibitor
M. Watson, T. Pesnot, Andrew Scott, A. Huxley +4 more
2019Cancer Chemistry0 citations
Semantic Scholar
Abstract 5581: Development of 2ndgeneration indoleamine 2,3-dioxygenase 1 (IDO1) selective inhibitors
T. Pesnot, S. Mahale, P. Macfaul, J. Maclean +10 more
20170 citations
Semantic Scholar
Structure of truncated Norcoclaurine Synthase from Thalictrum flavum
A. Sula, B. Lichman, T. Pesnot, J. Ward +2 more
20170 citations
Semantic Scholar
Structure of truncated Norcoclaurine Synthase from Thalictrum flavum with product mimic
A. Sula, B. Lichman, T. Pesnot, J. Ward +2 more
20170 citations
Semantic Scholar
UDP-sugar derivatives reveal novel dynamic features of blood group glycosyltransferases
R. Jørgensen, T. Pesnot, Gerd K. Wagner, M. Palcic
20110 citations Open access
Semantic Scholar
Crystal structure of the Fucosylgalactoside alpha N-acetylgalactosaminyltransferase (GTA, cisAB mutant L266G, G268A)
T. Pesnot, R. Jørgensen, M. Palcic, Gerd K. Wagner
20100 citations
Semantic Scholar
Structural basis for a new mode of glycosyltransferase inhibition
R. Jørgensen, T. Pesnot, M. Palcic, Gerd K. Wagner
20100 citations Open access
Semantic Scholar
Crystal structure of the Fucosylgalactoside alpha N-acetylgalactosaminyltransferase (GTA, cisAB mutant L266G, G268A) in complex with UDP
T. Pesnot, R. Jørgensen, M. Palcic, Gerd K. Wagner
20100 citations
Semantic Scholar

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