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P. Driscoll · SciRah

Researcher profile · Semantic Scholar

P. Driscoll

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P. Driscoll — researcher profile on SciRah

h-index: 51
Works: 194
Citations: 11K

Most-cited papers

Anaplastic lymphoma kinase spares organ growth during nutrient restriction in Drosophila.
Louise Y. Cheng, Andrew P Bailey, S. Leevers, T. J. Ragan +2 more
2011Cell231 citations Open access
Semantic Scholar
Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers
Catherine Houlihan, N. Vora, T. Byrne, D. Lewer +318 more
2020The Lancet222 citations Open access
Semantic Scholar
Small Molecule Inhibitors of the Neuropilin-1 Vascular Endothelial Growth Factor A (VEGF-A) Interaction
Ashley N. Jarvis, C. Allerston, Haiyan Jia, Birger Herzog +16 more
2010Journal of Medicinal Chemistry189 citations Open access
Semantic Scholar
The OtsAB Pathway Is Essential for Trehalose Biosynthesis in Mycobacterium tuberculosis*
Helen N. Murphy, G. Stewart, V. Mischenko, A. Apt +5 more
2005Journal of Biological Chemistry138 citations Open access
Semantic Scholar
Characterization of a Bicyclic Peptide Neuropilin-1 (NP-1) Antagonist (EG3287) Reveals Importance of Vascular Endothelial Growth Factor Exon 8 for NP-1 Binding and Role of NP-1 in KDR Signaling*
Haiyan Jia, Azadeh Bagherzadeh, B. Hartzoulakis, Ashley N. Jarvis +10 more
2006Journal of Biological Chemistry136 citations Open access
Semantic Scholar
Identifying strategies to target the metabolic flexibility of tumours.
Andrés Méndez-Lucas, Wei Lin, P. Driscoll, Nathalie LeGrave +12 more
2020Nature Metabolism133 citations Open access
Semantic Scholar
Targeting VEGF signalling via the neuropilin co-receptor.
S. Djordjević, P. Driscoll
2013Drug Discovery Today109 citations Open access
Semantic Scholar
Clustering of Genetically Defined Allele Classes in the Caenorhabditis elegans DAF-2 Insulin/IGF-1 Receptor
Dhaval S. Patel, A. Garza-Garcia, M. Nanji, J. McElwee +3 more
2008Genetics107 citations Open access
Semantic Scholar
Evidence for the local evolution of mechanisms underlying limb regeneration in salamanders.
A. Garza-Garcia, P. Driscoll, J. Brockes
2010Integrative and Comparative Biology106 citations Open access
Semantic Scholar
Structural insight into substrate specificity and regulatory mechanisms of phosphoinositide 3-kinases.
S. Djordjević, P. Driscoll
2002TIBS -Trends in Biochemical Sciences. Regular ed106 citations
Semantic Scholar
Structural and Functional Integration of the PLCγ Interaction Domains Critical for Regulatory Mechanisms and Signaling Deregulation
T. D. Bunney, D. Esposito, C. Mas-Droux, Ekatarina Lamber +6 more
2012Structure85 citations Open access
Semantic Scholar
Measuring IgA Anti-β2-Glycoprotein I and IgG/IgA Anti-Domain I Antibodies Adds Value to Current Serological Assays for the Antiphospholipid Syndrome
C. Pericleous, I. Ferreira, O. Borghi, F. Pregnolato +9 more
2016PLoS ONE84 citations Open access
Semantic Scholar
Rhythmic glucose metabolism regulates the redox circadian clockwork in human red blood cells
Ratnasekhar Ch, G. Rey, Sandipan Ray, P. Jha +8 more
2021Nature Communications79 citations Open access
Semantic Scholar
Glucose catabolism in liver tumors induced by c-MYC can be sustained by various PKM1/PKM2 ratios and pyruvate kinase activities
Andrés Méndez-Lucas, Xiao-Lei Li, Jun-Jie Hu, L. Che +9 more
2017Cancer Research72 citations Open access
Semantic Scholar
The X-ray Crystal Structure and Putative Ligand-derived Peptide Binding Properties of γ-Aminobutyric Acid Receptor Type A Receptor-associated Protein*
D. Knight, Richard J. Harris, M. McAlister, J. Phelan +4 more
2002Journal of Biological Chemistry72 citations Open access
Semantic Scholar
Characterization of Phospholipase Cγ Enzymes with Gain-of-Function Mutations*
K. L. Everett, T. D. Bunney, Y. Yoon, F. Rodrigues-Lima +8 more
2009Journal of Biological Chemistry69 citations Open access
Semantic Scholar
The 3D solution structure of the C-terminal region of Ku86 (Ku86CTR).
Richard J. Harris, D. Esposito, A. Sankar, J. Maman +3 more
2004Journal of Molecular Biology68 citations
Semantic Scholar
Solution Structure and Phylogenetics of Prod1, a Member of the Three-Finger Protein Superfamily Implicated in Salamander Limb Regeneration
A. Garza-Garcia, Richard J. Harris, D. Esposito, P. B. Gates +1 more
2009PLoS ONE67 citations Open access
Semantic Scholar
NMR structure of a complex between the VirB9/VirB7 interaction domains of the pKM101 type IV secretion system
R. Bayliss, Richard J. Harris, L. Coutte, Amy L. Monier +4 more
2007Proceedings of the National Academy of Sciences of the United States of America60 citations Open access
Semantic Scholar
Investigation of the effect of molecular properties on the binding kinetics of a ligand to its biological target
Duncan C. Miller, G. Lunn, P. Jones, Y. Sabnis +2 more
201258 citations Open access
Semantic Scholar
Nonenzymatic gluconeogenesis-like formation of fructose 1,6-bisphosphate in ice
C. Messner, P. Driscoll, G. Piedrafita, M. D. De Volder +1 more
2017Proceedings of the National Academy of Sciences of the United States of America53 citations Open access
Semantic Scholar
Solution NMR investigation of the CD95/FADD homotypic death domain complex suggests lack of engagement of the CD95 C terminus.
D. Esposito, A. Sankar, N. Morgner, C. Robinson +2 more
2010Structure52 citations Open access
Semantic Scholar
Rac Regulates Its Effector Phospholipase Cγ2 through Interaction with a Split Pleckstrin Homology Domain
Claudia Walliser, Michael Retlich, Richard J. Harris, K. L. Everett +7 more
2008Journal of Biological Chemistry52 citations Open access
Semantic Scholar
The impact of physiological metabolite levels on serine uptake, synthesis and utilization in cancer cells
Marc Hennequart, Christiaan F. Labuschagne, Mylène Tajan, Steven E. Pilley +4 more
2021Nature Communications49 citations Open access
Semantic Scholar
ALDH1L2 regulation of formate, formyl-methionine, and ROS controls cancer cell migration and metastasis.
Marc Hennequart, Steven E. Pilley, Christiaan F. Labuschagne, Jack Coomes +16 more
2023Cell Reports40 citations Open access
Semantic Scholar
Functional cross-talk between allosteric effects of activating and inhibiting ligands underlies PKM2 regulation
Jamie A. Macpherson, Alina Theisen, L. Masino, Louise Fets +8 more
2018bioRxiv40 citations Open access
Semantic Scholar
Combinatorial Domain Hunting: An effective approach for the identification of soluble protein domains adaptable to high‐throughput applications
S. Reich, Loretto H. Puckey, Caroline L. Cheetham, Richard J. Harris +8 more
2006Protein Science40 citations Open access
Semantic Scholar
Solution structure of the inner DysF domain of myoferlin and implications for limb girdle muscular dystrophy type 2b.
P. Patel, Richard J. Harris, S. Geddes, E. Strehle +5 more
2008Journal of Molecular Biology39 citations Open access
Semantic Scholar
Alternative modes of binding of proteins with tandem SH2 domains
R. O'brien, D. Renzoni, M. Waterfield, P. Driscoll +5 more
2008Protein Science39 citations Open access
Semantic Scholar
Characterization of Vibrio cholerae Hfq Provides Novel Insights into the Role of the Hfq C-Terminal Region
Helen A. Vincent, Charlotte A. Henderson, T. J. Ragan, A. Garza-Garcia +6 more
2012Journal of Molecular Biology36 citations Open access
Semantic Scholar
MCT2 mediates concentration-dependent inhibition of glutamine metabolism by MOG
Louise Fets, P. Driscoll, Fiona Grimm, Aakriti Jain +14 more
2018Nature Chemical Biology33 citations Open access
Semantic Scholar
An engineered photoswitchable mammalian pyruvate kinase
Stefanie M. Gehrig, Jamie A. Macpherson, P. Driscoll, Alastair Symon +5 more
2017The FEBS Journal32 citations Open access
Semantic Scholar
Structural Homology between the C-Terminal Domain of the PapC Usher and Its Plug
B. Ford, A. T. Rêgo, T. J. Ragan, J. Pinkner +4 more
2010Journal of Bacteriology32 citations Open access
Semantic Scholar
Perturbation of the gut microbiota by antibiotics results in accelerated breast tumour growth and metabolic dysregulation
Benjamin M. Kirkup, A. McKee, Kate A. Makin, Jack Paveley +17 more
2019bioRxiv30 citations Open access
Semantic Scholar
DNA fragmentation-based combinatorial approaches to soluble protein expression Part I. Generating DNA fragment libraries.
C. Prodromou, R. Savva, P. Driscoll
2007Drug Discovery Today27 citations
Semantic Scholar
Synthesis of orthogonally protected lanthionines.
M. Mustapa, Richard J. Harris, Nives Bulic-Subanovic, Susan L. Elliott +8 more
2003Journal of Organic Chemistry27 citations Open access
Semantic Scholar
Scalable and robust SARS-CoV-2 testing in an academic center
J. Aitken, Karen Ambrose, S. Barrell, R. Beale +282 more
2020Nature Biotechnology26 citations Open access
Semantic Scholar
Mechanism of Action of Secreted Newt Anterior Gradient Protein
Kathrin S. Grassme, A. Garza-Garcia, J. Delgado, James W. Godwin +4 more
2016PLoS ONE26 citations Open access
Semantic Scholar
Solution NMR studies of antiamoebin, a membrane channel-forming polypeptide.
T. P. Galbraith, R. Harris, P. Driscoll, B. Wallace
2003Biophysical Journal26 citations Open access
Semantic Scholar
Three-dimensional solution structure and conformational plasticity of the N-terminal scavenger receptor cysteine-rich domain of human CD5.
A. Garza-Garcia, D. Esposito, Wolfgang Rieping, Richard J. Harris +3 more
2008Journal of Molecular Biology20 citations
Semantic Scholar
Evaluating the conformation of recombinant domain I of β2-glycoprotein I and its interaction with human monoclonal antibodies
C. Pericleous, J. Miles, D. Esposito, A. Garza-Garcia +7 more
2011Molecular Immunology18 citations Open access
Semantic Scholar
Flexible Stoichiometry and Asymmetry of the PIDDosome Core Complex by Heteronuclear NMR Spectroscopy and Mass Spectrometry
Lily A. Nematollahi, A. Garza-Garcia, Cherine Bechara, D. Esposito +3 more
2015Journal of Molecular Biology16 citations Open access
Semantic Scholar
Volume Determination with Two Standards Allows Absolute Quantification and Improved Chemometric Analysis of Metabolites by NMR from Submicroliter Samples
T. J. Ragan, Andrew P Bailey, Alex P. Gould, P. Driscoll
2013Analytical Chemistry14 citations Open access
Semantic Scholar
Structural insights into the catalytic mechanism of Trypanosoma cruzi GPXI (glutathione peroxidase-like enzyme I).
Shreenal Patel, S. Hussain, Richard J. Harris, S. Sardiwal +4 more
2010Biochemical Journal13 citations Open access
Semantic Scholar
DNA fragmentation based combinatorial approaches to soluble protein expression Part II: library expression, screening and scale-up.
R. Savva, C. Prodromou, P. Driscoll
2007Drug Discovery Today13 citations
Semantic Scholar
Characterization and manipulation of the Pseudomonas aeruginosa dimethylarginine dimethylaminohydrolase monomer--dimer equilibrium.
M. Plevin, B. S. Magalhães, Richard J. Harris, A. Sankar +2 more
2004Journal of Molecular Biology13 citations Open access
Semantic Scholar
Synthesis of a cyclic peptide containing norlanthionine: effect of the thioether bridge on peptide conformation.
M. Mustapa, Richard J. Harris, D. Esposito, N. Chubb +4 more
2003Journal of Organic Chemistry12 citations
Semantic Scholar
Dynamic Allostery in PLCγ1 and Its Modulation by a Cancer Mutation Revealed by MD Simulation and NMR
H. Koss, T. D. Bunney, D. Esposito, M. Martins +2 more
2018Biophysical Journal11 citations Open access
Semantic Scholar
Biophysical and cell-based evidence for differential interactions between the death domains of CD95/Fas and FADD
B. Ferguson, D. Esposito, J. Jovanović, A. Sankar +2 more
2007Cell Death and Differentiation11 citations
Semantic Scholar
Letter to the Editor: 1H, 15N, and 13C chemical shift assignments of the resuscitation promoting factor domain of Rv1009 from Mycobacterium tuberculosis
M. Cohen-Gonsaud, P. Barthe, F. Pommier, Richard J. Harris +3 more
200411 citations
Semantic Scholar

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