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K. Zwicker · SciRah

Researcher profile · Semantic Scholar

K. Zwicker

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K. Zwicker — researcher profile on SciRah

h-index: 34
Works: 69
Citations: 3,042

Most-cited papers

The iron–sulphur protein Ind1 is required for effective complex I assembly
K. Bych, S. Kerscher, Daili J. Netz, A. J. Pierik +5 more
2008EMBO Journal174 citations Open access
Semantic Scholar
Molecular Basis for Atovaquone Binding to the Cytochrome bc1 Complex*
J. Kessl, Benjamin B. Lange, Torsten Merbitz-Zahradnik, K. Zwicker +6 more
2003Journal of Biological Chemistry147 citations Open access
Semantic Scholar
A Central Functional Role for the 49-kDa Subunit within the Catalytic Core of Mitochondrial Complex I*
Noushin Kashani-Poor, K. Zwicker, S. Kerscher, U. Brandt
2001Journal of Biological Chemistry145 citations Open access
Semantic Scholar
Proton pumping by NADH:ubiquinone oxidoreductase. A redox driven conformational change mechanism?
U. Brandt, S. Kerscher, Stefan Dröse, K. Zwicker +1 more
2003FEBS Letters137 citations
Semantic Scholar
Architecture of complex I and its implications for electron transfer and proton pumping
V. Zickermann, S. Kerscher, K. Zwicker, Maja A. Tocilescu +2 more
2009Biochimica et Biophysica Acta110 citations Open access
Semantic Scholar
Yarrowia lipolytica, a yeast genetic system to study mitochondrial complex I.
S. Kerscher, Stefan Dröse, K. Zwicker, V. Zickermann +1 more
2002Biochimica et Biophysica Acta110 citations Open access
Semantic Scholar
Functional Dissection of the Proton Pumping Modules of Mitochondrial Complex I
Stefan Dröse, S. Krack, L. Sokolová, K. Zwicker +10 more
2011PLoS Biology109 citations Open access
Semantic Scholar
Exploring the Ubiquinone Binding Cavity of Respiratory Complex I*
Maja A. Tocilescu, U. Fendel, K. Zwicker, S. Kerscher +1 more
2007Journal of Biological Chemistry108 citations Open access
Semantic Scholar
A salvage pathway maintains highly functional respiratory complex I
Karolina Szczepanowska, Katharina Senft, J. Heidler, Marija Herholz +17 more
2020Nature Communications106 citations Open access
Semantic Scholar
The LYR protein subunit NB4M/NDUFA6 of mitochondrial complex I anchors an acyl carrier protein and is essential for catalytic activity
H. Angerer, M. Radermacher, M. Mańkowska, Mirco Steger +5 more
2014Proceedings of the National Academy of Sciences of the United States of America101 citations Open access
Semantic Scholar
Biophysical and structural characterization of proton-translocating NADH-dehydrogenase (complex I) from the strictly aerobic yeast Yarrowia lipolytica.
Rogieh Djafarzadeh, S. Kerscher, K. Zwicker, Michael Radermacher +3 more
2000Biochimica et Biophysica Acta101 citations Open access
Semantic Scholar
Quinone binding and reduction by respiratory complex I.
Maja A. Tocilescu, V. Zickermann, K. Zwicker, U. Brandt
2010Biochimica et Biophysica Acta84 citations Open access
Semantic Scholar
The Rieske protein from Paracoccus denitrificans is inserted into the cytoplasmic membrane by the twin‐arginine translocase
J. Bachmann, B. Bauer, K. Zwicker, B. Ludwig +1 more
2006The FEBS Journal84 citations Open access
Semantic Scholar
Locking loop movement in the ubiquinone pocket of complex I disengages the proton pumps
Alfredo Cabrera-Orefice, E. G. Yoga, C. Wirth, K. Siegmund +5 more
2018Nature Communications82 citations Open access
Semantic Scholar
The role of a conserved tyrosine in the 49-kDa subunit of complex I for ubiquinone binding and reduction.
Maja A. Tocilescu, U. Fendel, K. Zwicker, Stefan Dröse +2 more
2010Biochimica et Biophysica Acta80 citations Open access
Semantic Scholar
Accessory NUMM (NDUFS6) subunit harbors a Zn-binding site and is essential for biogenesis of mitochondrial complex I
Katarzyna Kmita, C. Wirth, Judith Warnau, Sergio Guerrero‐Castillo +6 more
2015Proceedings of the National Academy of Sciences of the United States of America78 citations Open access
Semantic Scholar
A scaffold of accessory subunits links the peripheral arm and the distal proton pumping module of mitochondrial complex I
H. Angerer, K. Zwicker, Zibiernisha Wumaier, L. Sokolová +8 more
2011Biochemical Journal78 citations Open access
Semantic Scholar
Functional Significance of Conserved Histidines and Arginines in the 49-kDa Subunit of Mitochondrial Complex I*
L. Grgic, K. Zwicker, Noushin Kashani-Poor, S. Kerscher +1 more
2004Journal of Biological Chemistry73 citations Open access
Semantic Scholar
Full recovery of the NADH:ubiquinone activity of complex I (NADH:ubiquinone oxidoreductase) from Yarrowia lipolytica by the addition of phospholipids.
Stefan Dröse, K. Zwicker, U. Brandt
2002Biochimica et Biophysica Acta73 citations Open access
Semantic Scholar
The Redox-Bohr Group Associated with Iron-Sulfur Cluster N2 of Complex I*
K. Zwicker, A. Galkin, Stefan Dröse, L. Grgic +2 more
2006Journal of Biological Chemistry71 citations Open access
Semantic Scholar
Function of Conserved Acidic Residues in the PSST Homologue of Complex I (NADH:Ubiquinone Oxidoreductase) from Yarrowia lipolytica *
Pamela M. Ahlers, K. Zwicker, S. Kerscher, U. Brandt
2000Journal of Biological Chemistry65 citations Open access
Semantic Scholar
Compound heterozygosity for severe and hypomorphic NDUFS2 mutations cause non-syndromic LHON-like optic neuropathy
S. Gerber, Martina G. Ding, X. Gérard, K. Zwicker +12 more
2016Journal of Medical Genetics53 citations
Semantic Scholar
Exploring the Catalytic Core of Complex I by Yarrowia lipolytica Yeast Genetics
S. Kerscher, Noushin Kashani-Poor, K. Zwicker, V. Zickermann +1 more
2001Journal of Bioenergetics and Biomembranes52 citations
Semantic Scholar
Tight binding of NADPH to the 39-kDa subunit of complex I is not required for catalytic activity but stabilizes the multiprotein complex.
A. Abdrakhmanova, K. Zwicker, S. Kerscher, V. Zickermann +1 more
2006Biochimica et Biophysica Acta48 citations Open access
Semantic Scholar
Two Aspartic Acid Residues in the PSST-Homologous NUKM Subunit of Complex I from Yarrowia lipolytica Are Essential for Catalytic Activity*
Aurelio Garofano, K. Zwicker, S. Kerscher, Pamela M. Okun +1 more
2003Journal of Biological Chemistry46 citations Open access
Semantic Scholar
Essential role of accessory subunit LYRM6 in the mechanism of mitochondrial complex I
Etienne Galemou Yoga, K. Parey, Amina Djurabekova, Outi Haapanen +5 more
2020Nature Communications44 citations Open access
Semantic Scholar
Elimination of the disulfide bridge in the Rieske iron-sulfur protein allows assembly of the [2Fe-2S] cluster into the Rieske protein but damages the ubiquinol oxidation site in the cytochrome bc1 complex.
Torsten Merbitz-Zahradnik, K. Zwicker, J. Nett, T. Link +1 more
2003Biochemistry42 citations
Semantic Scholar
Challenges in elucidating structure and mechanism of proton pumping NADH:ubiquinone oxidoreductase (complex I)
V. Zickermann, Stefan Dröse, Maja A. Tocilescu, K. Zwicker +2 more
2008Journal of Bioenergetics and Biomembranes41 citations
Semantic Scholar
Manganese ions induce H2O2 generation at the ubiquinone binding site of mitochondrial complex II.
Erik Bonke, K. Zwicker, Stefan Dröse
2015Archives of Biochemistry and Biophysics39 citations
Semantic Scholar
Accessory subunit NUYM (NDUFS4) is required for stability of the electron input module and activity of mitochondrial complex I.
Flora Kahlhöfer, Katarzyna Kmita, I. Wittig, K. Zwicker +1 more
2017Biochimica et Biophysica Acta - Bioenergetics38 citations Open access
Semantic Scholar
Heterologous production in Wolinella succinogenes and characterization of the quinol:fumarate reductase enzymes from Helicobacter pylori and Campylobacter jejuni.
Mauro Mileni, F. MacMillan, C. Tziatzios, K. Zwicker +4 more
2006Biochemical Journal38 citations Open access
Semantic Scholar
Binding of detergents and inhibitors to bovine complex I - a novel purification procedure for bovine complex I retaining full inhibitor sensitivity.
J. Okun, V. Zickermann, K. Zwicker, H. Schägger +1 more
2000Biochimica et Biophysica Acta37 citations Open access
Semantic Scholar
The iron load of lipocalin-2 (LCN-2) defines its pro-tumour function in clear-cell renal cell carcinoma
C. Rehwald, M. Schnetz, A. Urbschat, C. Mertens +10 more
2019British Journal of Cancer36 citations Open access
Semantic Scholar
Reconstitution of bacteriorhodopsin and ATP synthase from Micrococcus luteus into liposomes of the purified main tetraether lipid from Thermoplasma acidophilum: proton conductance and light-driven ATP synthesis.
H. Freisleben, K. Zwicker, P. Ježek, G. John +3 more
1995Chemistry and Physics of Lipids35 citations
Semantic Scholar
Functional sulfurtransferase is associated with mitochondrial complex I from Yarrowia lipolytica, but is not required for assembly of its iron–sulfur clusters
A. Abdrakhmanova, K. Dobrynin, K. Zwicker, S. Kerscher +1 more
2005FEBS Letters34 citations Open access
Semantic Scholar
Heme-copper terminal oxidase using both cytochrome c and ubiquinol as electron donors
Ye Gao, Björn Meyer, L. Sokolová, K. Zwicker +4 more
2012Proceedings of the National Academy of Sciences of the United States of America31 citations Open access
Semantic Scholar
Manganese ions enhance mitochondrial H2O2 emission from Krebs cycle oxidoreductases by inducing permeability transition.
Erik Bonke, Ilka Siebels, K. Zwicker, Stefan Dröse
2016Free Radical Biology & Medicine29 citations
Semantic Scholar
Relaxation filtered hyperfine (REFINE) spectroscopy: a novel tool for studying overlapping biological electron paramagnetic resonance signals applied to mitochondrial complex I.
Thorsten Maly, F. MacMillan, K. Zwicker, Noushin Kashani-Poor +2 more
2004Biochemistry28 citations
Semantic Scholar
Hypoxic reoxygenation during initial reperfusion attenuates cardiac dysfunction and limits ischemia-reperfusion injury after cardioplegic arrest in a porcine model.
U. Abdel-Rahman, P. Risteski, K. Tizi, S. Kerscher +5 more
2009Journal of Thoracic and Cardiovascular Surgery26 citations Open access
Semantic Scholar
Synthesis and inhibitory action of novel acetogenin mimics with bovine heart mitochondrial complex I.
Takeshi Hamada, Naoya Ichimaru, Masato Abe, D. Fujita +5 more
2004Biochemistry25 citations
Semantic Scholar
Multifrequency pulsed electron paramagnetic resonance on metalloproteins.
Sevdalina Lyubenova, Thorsten Maly, K. Zwicker, U. Brandt +2 more
2010Accounts of Chemical Research22 citations
Semantic Scholar
Asymmetric and Redox-specific Binding of Quinone and Quinol at Center N of the Dimeric Yeast Cytochrome bc1 Complex
R. Covian, K. Zwicker, F. Rotsaert, B. Trumpower
2007Journal of Biological Chemistry21 citations Open access
Semantic Scholar
Coi1 is a novel assembly factor of the yeast complex III–complex IV supercomplex
R. K. Singhal, C. Kruse, J. Heidler, Valentina Strecker +6 more
2017Molecular Biology of the Cell19 citations Open access
Semantic Scholar
Characterization of a subcomplex of mitochondrial NADH:ubiquinone oxidoreductase (complex I) lacking the flavoprotein part of the N-module.
V. Zickermann, K. Zwicker, Maja A. Tocilescu, S. Kerscher +1 more
2007Biochimica et Biophysica Acta19 citations Open access
Semantic Scholar
Structure-function relationships in mitochondrial complex I of the strictly aerobic yeast Yarrowia lipolytica.
U. Brandt, A. Abdrakhmanova, V. Zickermann, A. Galkin +3 more
2005Biochemical Society Transactions19 citations
Semantic Scholar
Effect of the triaminopyridine flupirtine on calcium uptake, membrane potential and ATP synthesis in rat heart mitochondria
G. Zimmer, M. Balakirev, K. Zwicker, Michael Hofmann +2 more
1998British Journal of Pharmacology17 citations Open access
Semantic Scholar
Cluster N1 of complex I from Yarrowia lipolytica studied by pulsed EPR spectroscopy
Thorsten Maly, L. Grgic, K. Zwicker, V. Zickermann +2 more
2006JBIC Journal of Biological Inorganic Chemistry16 citations
Semantic Scholar
Histidine 129 in the 75-kDa Subunit of Mitochondrial Complex I from Yarrowia lipolytica Is Not a Ligand for [Fe4S4] Cluster N5 but Is Required for Catalytic Activity*
Antje Waletko, K. Zwicker, A. Abdrakhmanova, V. Zickermann +2 more
2005Journal of Biological Chemistry16 citations Open access
Semantic Scholar
New pulsed EPR methods and their application to characterize mitochondrial complex I.
Thorsten Maly, K. Zwicker, A. Cernescu, U. Brandt +1 more
2009Biochimica et Biophysica Acta14 citations Open access
Semantic Scholar
Molecular Basis for Atovaquone Binding to the Cytochrome bc 1 Complex *
J. Kessl, Benjamin B. Lange, Torsten Merbitz-Zahradnik, K. Zwicker +6 more
11 citations
Semantic Scholar

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S. Kerscher×21
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V. Zickermann×19
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Stefan Dröse×10
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Maja A. Tocilescu

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