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N. Droin · SciRah

Researcher profile · Semantic Scholar

N. Droin

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N. Droin — researcher profile on SciRah

h-index: 63
Works: 221
Citations: 18K

Most-cited papers

Elevated Calprotectin and Abnormal Myeloid Cell Subsets Discriminate Severe from Mild COVID-19
A. Silvin, Nicolas Chapuis, G. Dunsmore, A. Goubet +41 more
2020Cell764 citations Open access
Semantic Scholar
Genomic characterization of metastatic breast cancers
F. Bertucci, C. Ng, A. Patsouris, N. Droin +24 more
2019Nature591 citations
Semantic Scholar
Trastuzumab deruxtecan in metastatic breast cancer with variable HER2 expression: the phase 2 DAISY trial
F. Mosele, É. Deluche, A. Lusque, L. Le Bescond +31 more
2023Nature Medicine381 citations Open access
Semantic Scholar
Outcome and molecular landscape of patients with PIK3CA-mutated metastatic breast cancer.
F. Mosele, B. Stefanovska, A. Lusque, A. T. Dien +18 more
2020Annals of Oncology272 citations Open access
Semantic Scholar
CD103+CD8+ TRM Cells Accumulate in Tumors of Anti-PD-1-Responder Lung Cancer Patients and Are Tumor-Reactive Lymphocytes Enriched with Tc17
S. Corgnac, Ines Malenica, L. Mezquita, É. Auclin +18 more
2020Cell Reports Medicine153 citations Open access
Semantic Scholar
TET2 deficiency causes germinal center hyperplasia, impairs plasma cell differentiation and promotes B-cell lymphomagenesis
Pilar M. Dominguez, H. Ghamlouch, Wojciech Rosikiewicz, Parveen Kumar +30 more
2018Cancer Discovery148 citations Open access
Semantic Scholar
Biology and prognostic impact of clonal plasmacytoid dendritic cells in chronic myelomonocytic leukemia
Nolwenn Lucas, M. Duchmann, P. Rameau, Floriane Noël +19 more
2019Leukemia99 citations
Semantic Scholar
Clinical, molecular, and prognostic correlates of number, type, and functional localization of TET2 mutations in chronic myelomonocytic leukemia (CMML)—a study of 1084 patients
G. Coltro, A. Mangaonkar, T. Lasho, C. Finke +15 more
2019Leukemia99 citations
Semantic Scholar
Cancer induces a stress ileopathy depending on B-adrenergic receptors and promoting dysbiosis that contribute to carcinogenesis.
Satoru Yonekura, S. Terrisse, C. Alves Costa Silva, A. Lafarge +43 more
2021Cancer Discovery94 citations Open access
Semantic Scholar
RAS mutations drive proliferative chronic myelomonocytic leukemia via a KMT2A-PLK1 axis
Ryan M. Carr, D. Vorobyev, T. Lasho, D. Marks +31 more
2021Nature Communications90 citations Open access
Semantic Scholar
SRSF2 plays an unexpected role as reader of m5C on mRNA, linking epitranscriptomics to cancer
Hai-Li Ma, M. Bizet, Christelle Soares Da Costa, Frédéric Murisier +26 more
2023Molecules and Cells83 citations Open access
Semantic Scholar
A variant erythroferrone disrupts iron homeostasis in SF3B1-mutated myelodysplastic syndrome
S. Bondu, A. Alary, C. Lefèvre, Alexandre Houy +35 more
2019Science Translational Medicine77 citations Open access
Semantic Scholar
Prognostic Role of Gene Mutations in Chronic Myelomonocytic Leukemia Patients Treated With Hypomethylating Agents
M. Duchmann, Fevzi F. Yalniz, A. Sanna, D. Sallman +17 more
2018EBioMedicine77 citations Open access
Semantic Scholar
LBA1 Unraveling the mechanism of action and resistance to trastuzumab deruxtecan (T-DXd): Biomarker analyses from patients from DAISY trial
M. F. Mosele, A. Lusque, V. Diéras, E. Deluche +15 more
2022Annals of Oncology59 citations Open access
Semantic Scholar
Ontogenic changes in hematopoietic hierarchy determine pediatric specificity and disease phenotype in fusion oncogene-driven myeloid leukemia.
Cécile K. Lopez, Esteve Noguera, V. Stavropoulou, E. Robert +32 more
2019Cancer Discovery49 citations Open access
Semantic Scholar
A miR-150/TET3 pathway regulates the generation of mouse and human non-classical monocyte subset
Dorothée Sélimoglu-Buet, J. Rivière, H. Ghamlouch, Laura Bencheikh +15 more
2018Nature Communications49 citations Open access
Semantic Scholar
Asxl1loss cooperates with oncogenic Nras in mice to reprogram immune microenvironment and drive leukemic transformation.
Xiaona You, Fabao Liu, M. Binder, A. Vedder +26 more
2021Blood48 citations Open access
Semantic Scholar
Genetic characterization of B-cell prolymphocytic leukemia: a prognostic model involving MYC and TP53.
E. Chapiro, Elodie Pramil, M. Diop, Damien Roos-Weil +36 more
2019Blood43 citations Open access
Semantic Scholar
Decitabine Versus Hydroxyurea for Advanced Proliferative Chronic Myelomonocytic Leukemia: Results of a Randomized Phase III Trial Within the EMSCO Network
R. Itzykson, V. Santini, S. Thepot, L. Adès +29 more
2022Journal of Clinical Oncology40 citations
Semantic Scholar
Dynamic gene regulation by nuclear colony-stimulating factor 1 receptor in human monocytes and macrophages
Laura Bencheikh, M. Diop, J. Rivière, Aygun Imanci +9 more
2019Nature Communications34 citations Open access
Semantic Scholar
Familial predisposition to TP53/complex karyotype MDS and leukemia in DNA repair-deficient xeroderma pigmentosum.
A. Sarasin, S. Quentin, N. Droin, M. Sahbatou +19 more
2019Blood34 citations Open access
Semantic Scholar
Role of ASXL1 in Hematopoiesis and Myeloid Diseases
Xin Gao, Xiaona You, N. Droin, Lauren G. Banaszak +6 more
2022Experimental Hematology32 citations Open access
Semantic Scholar
Structural variation cooperates with permissive chromatin to control enhancer hijacking–mediated oncogenic transcription
G. Botten, Yuannyu Zhang, Kseniia Dudnyk, Y. Kim +14 more
2022Blood29 citations Open access
Semantic Scholar
A Recurrent Activating Missense Mutation in Waldenström Macroglobulinemia Affects the DNA Binding of the ETS Transcription Factor SPI1 and Enhances Proliferation.
Damien Roos-Weil, C. Decaudin, M. Armand, V. Della-Valle +32 more
2019Cancer Discovery29 citations Open access
Semantic Scholar
DNA damage and S phase-dependent E2F1 stabilization requires the cIAP1 E3-ubiquitin ligase and is associated with K63-poly-ubiquitination on lysine 161/164 residues
V. Glorian, Jennifer Allègre, J. Berthelet, Baptiste Dumétier +12 more
2017Cell Death and Disease29 citations Open access
Semantic Scholar
Biallelic inactivation of the retinoblastoma gene results in transformation of chronic myelomonocytic leukemia to a blastic plasmacytoid dendritic cell neoplasm: shared clonal origins of two aggressive neoplasms
M. Patnaik, T. Lasho, M. Howard, C. Finke +7 more
2018Blood Cancer Journal28 citations Open access
Semantic Scholar
Engraftment of chronic myelomonocytic leukemia cells in immunocompromised mice supports disease dependency on cytokines.
Yan-Yan Zhang, Liang He, Dorothée Sélimoglu-Buet, C. Jego +8 more
2017Blood Advances28 citations Open access
Semantic Scholar
Decitabine Versus Hydroxyurea for Advanced Proliferative CMML: Results of the Emsco Randomized Phase 3 Dacota Trial
R. Itzykson, V. Santini, C. Chaffaut, A. Lionel +28 more
202026 citations Open access
Semantic Scholar
Rucaparib in patients presenting a metastatic breast cancer with homologous recombination deficiency, without germline BRCA1/2 mutation.
A. Patsouris, Kadija Diop, O. Trédan, D. Nenciu +13 more
2020European Journal of Cancer25 citations Open access
Semantic Scholar
Cytokine-like protein 1-induced survival of monocytes suggests a combined strategy targeting MCL1 and MAPK in CMML.
Margaux Sevin, Franck Debeurme, L. Laplane, S. Badel +23 more
2021Blood23 citations Open access
Semantic Scholar
Serpin B1 defect and increased apoptosis of neutrophils in Cohen syndrome neutropenia
L. Duplomb, J. Rivière, G. Jego, R. Da Costa +22 more
2019Journal of molecular medicine23 citations
Semantic Scholar
Macrophage migration inhibitory factor is overproduced through EGR1 in TET2low resting monocytes
E. Pronier, Aygun Imanci, Dorothée Sélimoglu-Buet, Bouchra Badaoui +16 more
2022Communications Biology22 citations Open access
Semantic Scholar
Stepwise GATA1 and SMC3 mutations alter megakaryocyte differentiation in a Down syndrome leukemia model
B. Arkoun, E. Robert, Fabien Boudia, Stefania Mazzi +23 more
2022Journal of Clinical Investigation22 citations Open access
Semantic Scholar
Constitutive activation of RAS/MAPK pathway cooperates with trisomy 21 and is therapeutically exploitable in Down syndrome B-cell Leukemia
Anouchka P. Laurent, Aurélie Siret, C. Ignacimouttou, Kunjal Panchal +26 more
2020Clinical Cancer Research22 citations Open access
Semantic Scholar
Downregulation of TREM-like transcript-1 and collagen receptor α2 subunit, two novel RUNX1-targets, contributes to platelet dysfunction in familial platelet disorder with predisposition to acute myelogenous leukemia
A. C. Glembotsky, Dominika Sliwa, D. Bluteau, Nathalie Balayn +11 more
2018Haematologica22 citations Open access
Semantic Scholar
A noncanonical response to replication stress protects genome stability through ROS production, in an adaptive manner
S. Ragu, N. Droin, Gabriel Matos-Rodrigues, A. Barascu +11 more
2023Cell Death and Differentiation21 citations Open access
Semantic Scholar
RUBY: A phase II study testing rucaparib in germline (g) BRCA wild-type patients presenting metastatic breast cancer (mBC) with homologous recombination deficiency (HRD).
A. Patsouris, O. Trédan, D. Nenciu, A. Tran-Dien +12 more
2019Journal of Clinical Oncology21 citations
Semantic Scholar
Accelerated DNA replication fork speed due to loss of R-loops in myelodysplastic syndromes with SF3B1 mutation
D. Rombaut, C. Lefèvre, Tony Rached, S. Bondu +36 more
2024Nature Communications19 citations Open access
Semantic Scholar
Whole exome sequencing in molecular diagnostics of cancer decreases over time: evidence from a cost analysis in the French setting
A. Bayle, N. Droin, B. Besse, Z. Zou +7 more
2021European Journal of Health Economics18 citations
Semantic Scholar
SRSF2-P95H decreases JAK/STAT signaling in hematopoietic cells and delays myelofibrosis development in mice
C. Willekens, L. Laplane, Tracy Dagher, Camélia Benlabiod +22 more
2023Leukemia17 citations Open access
Semantic Scholar
Genomic Instability and Protumoral Inflammation Are Associated with Primary Resistance to Anti–PD-1 + Antiangiogenesis in Malignant Pleural Mesothelioma
F. Danlos, M. Texier, B. Job, S. Mouraud +39 more
2023Cancer Discovery16 citations Open access
Semantic Scholar
Multilayer intraclonal heterogeneity in chronic myelomonocytic leukemia
Allan Beke, L. Laplane, J. Rivière, Qin Yang +11 more
2019Haematologica16 citations Open access
Semantic Scholar
Integrative analysis of dysregulated microRNAs and mRNAs in multiple recurrent synchronized renal tumors from patients with von Hippel-Lindau disease
Charles-Henry Gattolliat, S. Couvé, G. Meurice, C. Oréar +14 more
2018International Journal of Oncology14 citations Open access
Semantic Scholar
The Polarity and Specificity of Antiviral T Lymphocyte Responses Determine Susceptibility to SARS-CoV-2 Infection in Patients with Cancer and Healthy Individuals
Jean-Eudes Fahrner, I. Lahmar, A. Goubet, Yacine Haddad +64 more
2022Cancer Discovery13 citations Open access
Semantic Scholar
Involvement of PBRM1 in VHL disease-associated clear cell renal cell carcinoma and its putative relationship with the HIF pathway
S. Gad, G. Le Teuff, B. Nguyen, V. Verkarre +15 more
2021Oncology Letters13 citations Open access
Semantic Scholar
Targeting heterochromatin eliminates chronic myelomonocytic leukemia malignant stem cells through reactivation of retroelements and immune pathways
D. Hidaoui, Audrey Porquet, R. Chelbi, Mathieu Bohm +15 more
2024Communications Biology10 citations Open access
Semantic Scholar
Germline mutation in the NBR1 gene involved in autophagy detected in a family with renal tumors.
Florine Adolphe, S. Ferlicot, V. Verkarre, Katia Posseme +11 more
2021Cancer Genetics10 citations Open access
Semantic Scholar
A constitutive BCL2 down-regulation aggravates the phenotype of PKD1-mutant-induced polycystic kidney disease
L. Duplomb, N. Droin, O. Bouchot, C. Thauvin-Robinet +11 more
2017Human Molecular Genetics10 citations Open access
Semantic Scholar
ANKRD26 is a new regulator of type I cytokine receptor signaling in normal and pathological hematopoiesis
F. Basso-Valentina, A. Donada, V. Manchev, Manuel Lisetto +19 more
2022bioRxiv8 citations Open access
Semantic Scholar
E2F1 binds to the peptide-binding groove within the BIR3 domain of cIAP1 and requires cIAP1 for chromatin binding
Jennifer Allègre, J. Cartier, V. Glorian, N. Droin +8 more
2018PLoS ONE8 citations Open access
Semantic Scholar

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