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E. Klussmann · SciRah

Researcher profile · Semantic Scholar

E. Klussmann

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E. Klussmann — researcher profile on SciRah

h-index: 47
Works: 170
Citations: 6,161

Most-cited papers

PDE3A mutations cause autosomal dominant hypertension with brachydactyly
P. Maass, A. Aydın, F. Luft, Carolin Schächterle +43 more
2015Nature Genetics152 citations Open access
Semantic Scholar
Direct Binding Between Orai1 and AC8 Mediates Dynamic Interplay Between Ca2+ and cAMP Signaling
D. Willoughby, K. L. Everett, M. Halls, Jonathan Pacheco +4 more
2012Science Signaling144 citations
Semantic Scholar
Themed Section: Novel cAMP Signalling Paradigms
Jessica Tröger, M. Moutty, P. Skroblin, E. Klussmann
2012112 citations
Semantic Scholar
Regulation of Sarcoplasmic Reticulum Ca2+ ATPase 2 (SERCA2) Activity by Phosphodiesterase 3A (PDE3A) in Human Myocardium
Faiyaz Ahmad, W. Shen, F. Vandeput, Nicolas Szabo‐Fresnais +6 more
2015Journal of Biological Chemistry77 citations Open access
Semantic Scholar
Small-molecule allosteric activators of PDE4 long form cyclic AMP phosphodiesterases
Faisa Omar, J. Findlay, Gemma Carfray, Robert W. Allcock +18 more
2019Proceedings of the National Academy of Sciences of the United States of America73 citations Open access
Semantic Scholar
Pharmacological targeting of AKAP-directed compartmentalized cAMP signalling.
Alessandro Dema, E. Perets, M. Schulz, V. Deák +1 more
2015Cellular Signalling70 citations Open access
Semantic Scholar
G protein-coupled estrogen receptor 1 mediates relaxation of coronary arteries via cAMP/PKA-dependent activation of MLCP.
Xuan Yu, Fen Li, E. Klussmann, J. Stallone +1 more
2014American Journal of Physiology. Endocrinology and Metabolism60 citations
Semantic Scholar
The Trafficking of the Water Channel Aquaporin-2 in Renal Principal Cells—a Potential Target for Pharmacological Intervention in Cardiovascular Diseases
T. Vukićević, M. Schulz, Dörte Faust, E. Klussmann
2016Frontiers in Pharmacology58 citations Open access
Semantic Scholar
Roles of A-Kinase Anchoring Proteins and Phosphodiesterases in the Cardiovascular System
Maria Ercu, E. Klussmann
2018Journal of Cardiovascular Development and Disease50 citations Open access
Semantic Scholar
Bimodal antagonism of PKA signalling by ARHGAP36
Rebecca L. Eccles, Maciej T. Czajkowski, Carolin Barth, Paul M. Müller +13 more
2016Nature Communications47 citations Open access
Semantic Scholar
Highly Functionalized Terpyridines as Competitive Inhibitors of AKAP–PKA Interactions
Gesa Schäfer, J. Milić, Adeeb Eldahshan, F. Götz +19 more
2013Angewandte Chemie45 citations Open access
Semantic Scholar
The A-Kinase Anchoring Protein (AKAP) Glycogen Synthase Kinase 3β Interaction Protein (GSKIP) Regulates β-Catenin through Its Interactions with Both Protein Kinase A (PKA) and GSK3β *
Alessandro Dema, M. F. Schröter, E. Perets, P. Skroblin +4 more
2016Journal of Biological Chemistry39 citations Open access
Semantic Scholar
A key phosphorylation site in AC8 mediates regulation of Ca2+-dependent cAMP dynamics by an AC8–AKAP79–PKA signalling complex
D. Willoughby, M. Halls, K. L. Everett, A. Ciruela +3 more
2012Journal of Cell Science39 citations Open access
Semantic Scholar
AKAP18δ Anchors and Regulates CaMKII Activity at Phospholamban-SERCA2 and RYR
C. Carlson, J. M. Aronsen, A. Bergan-Dahl, M. Moutty +18 more
2021Circulation Research38 citations Open access
Semantic Scholar
Phosphodiesterase 3A and Arterial Hypertension
Maria Ercu, L. Markó, Carolin Schächterle, D. Tsvetkov +36 more
2020Circulation36 citations Open access
Semantic Scholar
A-kinase-anchoring proteins coordinate inflammatory responses to cigarette smoke in airway smooth muscle.
W. Poppinga, I. Heijink, L. J. Holtzer, P. Skroblin +5 more
2015American Journal of Physiology - Lung cellular and Molecular Physiology35 citations Open access
Semantic Scholar
Endothelial PKA activity regulates angiogenesis by limiting autophagy through phosphorylation of ATG16L1
Xiao-Cheng Zhao, P. Nedvetsky, F. Stanchi, Anne-Clémence Vion +5 more
2019eLife34 citations Open access
Semantic Scholar
Anoctamin-4 is a bona fide Ca2+-dependent non-selective cation channel
Nadine Reichhart, S. Schöberl, S. Keckeis, Ahmad Samir Alfaar +14 more
2019Scientific Reports33 citations Open access
Semantic Scholar
Protein-protein interactions of PDE4 family members - Functions, interactions and therapeutic value.
E. Klussmann
2016Cellular Signalling33 citations Open access
Semantic Scholar
The crystal structure of the RhoA–AKAP-Lbc DH–PH domain complex
K. Abdul Azeez, S. Knapp, J. Fernandes, E. Klussmann +1 more
2014Biochemical Journal33 citations Open access
Semantic Scholar
Dimerization of cAMP phosphodiesterase-4 (PDE4) in living cells requires interfaces located in both the UCR1 and catalytic unit domains
G. Bolger, Allan J. Dunlop, Dong Meng, J. Day +4 more
2015Cellular Signalling32 citations Open access
Semantic Scholar
AKAP18:PKA-RIIα structure reveals crucial anchor points for recognition of regulatory subunits of PKA
F. Götz, Y. Roske, M. Schulz, Karolin Autenrieth +10 more
2016Biochemical Journal31 citations Open access
Semantic Scholar
Clinical Effects of Phosphodiesterase 3A Mutations in Inherited Hypertension With Brachydactyly
O. Toka, J. Tank, Carolin Schächterle, A. Aydın +22 more
2015HYPERTENSION30 citations Open access
Semantic Scholar
An AKAP-Lbc-RhoA interaction inhibitor promotes the translocation of aquaporin-2 to the plasma membrane of renal collecting duct principal cells
K. Schrade, Jessica Tröger, Adeeb Eldahshan, Kerstin Zühlke +23 more
2018PLoS ONE29 citations Open access
Semantic Scholar
Interaction between LIS1 and PDE4, and its role in cytoplasmic dynein function
Hannah Murdoch, S. Vadrevu, A. Prinz, Allan J. Dunlop +4 more
2011Journal of Cell Science24 citations Open access
Semantic Scholar
Mutant Phosphodiesterase 3A Protects From Hypertension-Induced Cardiac Damage
Maria Ercu, M. Mücke, Tamara Pallien, L. Markó +40 more
2022Circulation23 citations Open access
Semantic Scholar
New aspects in cardiac L-type Ca2+ channel regulation.
Tamara Pallien, E. Klussmann
2020Biochemical Society Transactions23 citations
Semantic Scholar
Vasopressin increases S261 phosphorylation in AQP2-P262L, a mutant in recessive nephrogenic diabetes insipidus.
C. Trimpert, Dennis T. M. van den Berg, R. Fenton, E. Klussmann +1 more
2012Nephrology, Dialysis and Transplantation23 citations
Semantic Scholar
Fluconazole Increases Osmotic Water Transport in Renal Collecting Duct through Effects on Aquaporin-2 Trafficking.
T. Vukićević, C. Hinze, Sandrine Baltzer, N. Himmerkus +10 more
2019Journal of the American Society of Nephrology22 citations Open access
Semantic Scholar
Small-molecule screening identifies modulators of aquaporin-2 trafficking.
J. Bogum, Dörte Faust, Kerstin Zühlke, Jenny Eichhorst +11 more
2013Journal of the American Society of Nephrology22 citations Open access
Semantic Scholar
Local cyclic adenosine monophosphate signalling cascades—Roles and targets in chronic kidney disease
Anastasiia Sholokh, E. Klussmann
2021Acta Physiologica21 citations Open access
Semantic Scholar
Culturing primary rat inner medullary collecting duct cells.
Dörte Faust, A. Geelhaar, B. Eisermann, Jenny Eichhorst +3 more
2013Journal of Visualized Experiments20 citations Open access
Semantic Scholar
Integrated Proteomics Unveils Nuclear PDE3A2 as a Regulator of Cardiac Myocyte Hypertrophy
Gunasekaran Subramaniam, K. Schleicher, D. Kovanich, Anna Zerio +17 more
2023Circulation Research19 citations Open access
Semantic Scholar
Cyclin-Dependent Kinase 18 Controls Trafficking of Aquaporin-2 and Its Abundance through Ubiquitin Ligase STUB1, Which Functions as an AKAP
Alessandro Dema, Dörte Faust, K. Lazarow, Marc Wippich +13 more
2020Cells19 citations Open access
Semantic Scholar
Mechanism for Targeting the A-kinase Anchoring Protein AKAP18δ to the Membrane*
Andreas Horner, F. Goetz, R. Tampé, E. Klussmann +1 more
2012Journal of Biological Chemistry19 citations Open access
Semantic Scholar
Protein kinase C enhances plasma membrane expression of cardiac L-type calcium channel, CaV1.2
T. Raifman, Prabodh Kumar, H. Haase, E. Klussmann +2 more
2017Channels17 citations Open access
Semantic Scholar
Pharmacological Interference With Protein-protein Interactions of Akinase Anchoring Proteins as a Strategy for the Treatment of Disease.
V. Deák, E. Klussmann
2016Current Drug Targets17 citations Open access
Semantic Scholar
AKAPS Act in a Two-Step Mechanism of Memory Acquisition
Lisa Scheunemann, P. Skroblin, Christian Hundsrucker, E. Klussmann +2 more
2013Journal of Neuroscience16 citations Open access
Semantic Scholar
Protein kinase A regulates C‐terminally truncated CaV1.2 in Xenopus oocytes: roles of N‐ and C‐termini of the α1C subunit
Shimrit Oz, Ines Pankonien, A. Belkacemi, V. Flockerzi +3 more
2017Journal of Physiology14 citations Open access
Semantic Scholar
The A-kinase Anchoring Protein GSKIP Regulates GSK3β Activity and Controls Palatal Shelf Fusion in Mice*
V. Deák, P. Skroblin, Carsten Dittmayer, K. Knobeloch +2 more
2015Journal of Biological Chemistry14 citations Open access
Semantic Scholar
Screening for small molecule disruptors of AKAP-PKA interactions.
Carolin Schächterle, F. Christian, J. Fernandes, E. Klussmann
2015Methods in molecular biology14 citations
Semantic Scholar
Mutations in phosphodiesterase 3A (PDE3A) Cause Hypertension Without Cardiac Damage.
Maria Ercu, Stephan Walter, E. Klussmann
2023HYPERTENSION12 citations
Semantic Scholar
Reconstitution of β-adrenergic regulation of CaV1.2: Rad-dependent and Rad-independent protein kinase A mechanisms
M. Katz, Suraj Subramaniam, Orna Chomsky-Hecht, V. Tsemakhovich +6 more
2020bioRxiv12 citations Open access
Semantic Scholar
Neurochondrin is an atypical RIIα-specific A-kinase anchoring protein
Jennifer Hermann, P. Skroblin, Daniela Bertinetti, Laura Hanold +6 more
2015Biochimica et Biophysica Acta11 citations Open access
Semantic Scholar
Many kinases for controlling the water channel aquaporin‐2
A. Kharin, E. Klussmann
2023Journal of Physiology10 citations Open access
Semantic Scholar
Reconstitution of β-adrenergic regulation of CaV1.2: Rad-dependent and Rad-independent protein kinase A mechanisms
M. Katz, Suraj Subramaniam, Orna Chomsky-Hecht, V. Tsemakhovich +5 more
2021Proceedings of the National Academy of Sciences of the United States of America8 citations Open access
Semantic Scholar
Small molecules for modulating the localisation of the water channel aquaporin-2—disease relevance and perspectives for targeting local cAMP signalling
Sandrine Baltzer, E. Klussmann
2019Naunyn-Schmiedeberg's Archives of Pharmacology7 citations
Semantic Scholar
The A-kinase anchoring protein ( AKAP ) glycogen synthase kinase 3 { beta } interaction protein ( GSKIP ) regulates { beta }-catenin through its interactions with both protein kinase A ( PKA ) and GSK 3 { beta }
Alessandro Dema, M. F. Schröter, E. Perets, P. Skroblin +4 more
20176 citations
Semantic Scholar
The Case| A handful of hypertension.
B. H. van den Born, Louise C Oskam, Majida Zidane, Carolin Schächterle +3 more
2016Kidney International6 citations Open access
Semantic Scholar
PDE3A as a Therapeutic Target for the Modulation of Compartmentalised Cyclic Nucleotide-Dependent Signalling
Swaroop Ranjan Pati, Anastasiia Sholokh, E. Klussmann
2025Cells4 citations Open access
Semantic Scholar

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Maria Ercu — researcher profile on SciRah

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P. Maass — researcher profile on SciRah

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