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R. Fenton · SciRah

Researcher profile · Semantic Scholar

R. Fenton

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R. Fenton — researcher profile on SciRah

h-index: 59
Works: 252
Citations: 10K

Most-cited papers

Single-Cell Transcriptome Atlas of Murine Endothelial Cells.
J. Kalucka, Laura P. M. H. de Rooij, J. Goveia, Katerina Rohlenova +31 more
2020Cell1,179 citations Open access
Semantic Scholar
Regulation of the Renal NaCl Cotransporter and Its Role in Potassium Homeostasis.
E. Hoorn, Martin Gritter, Catherina A. Cuevas, R. Fenton
2020Physiological Reviews131 citations Open access
Semantic Scholar
The vascular Ca2+-sensing receptor regulates blood vessel tone and blood pressure.
M. Schepelmann, P. Yarova, I. Lopez-Fernandez, T. Davies +16 more
2016American Journal of Physiology - Cell Physiology91 citations Open access
Semantic Scholar
Comparing Approaches to Normalize, Quantify, and Characterize Urinary Extracellular Vesicles
C. Blijdorp, Omar A Z Tutakhel, T. Hartjes, T. van den Bosch +18 more
2021Journal of the American Society of Nephrology81 citations Open access
Semantic Scholar
Renal tubular NHE3 is required in the maintenance of water and sodium chloride homeostasis
R. Fenton, S. Poulsen, Samantha de la Mora Chavez, M. Soleimani +2 more
2017Kidney International65 citations Open access
Semantic Scholar
Hypercalcemia induces targeted autophagic degradation of aquaporin-2 at the onset of nephrogenic diabetes insipidus.
S. Khositseth, Komgrid Charngkaew, Chatikorn Boonkrai, P. Somparn +5 more
2017Kidney International62 citations Open access
Semantic Scholar
In Primary Aldosteronism, Mineralocorticoids Influence Exosomal Sodium-Chloride Cotransporter Abundance.
M. Wolley, A. Wu, Sheng-Xin Xu, R. Gordon +2 more
2017Journal of the American Society of Nephrology59 citations Open access
Semantic Scholar
Aquaporin 2 regulation: implications for water balance and polycystic kidney diseases
E. Olesen, R. Fenton
2021Nature Reviews Nephrology56 citations
Semantic Scholar
Potassium homeostasis: sensors, mediators, and targets
A. McDonough, R. Fenton
2022Pflügers Archiv: European Journal of Physiology49 citations Open access
Semantic Scholar
CHIP regulates Aquaporin‐2 Quality Control and Body Water Homeostasis
Qi Wu, H. Moeller, D. A. Stevens, Rebekah Sanchez-Hodge +9 more
2017Journal of the American Society of Nephrology46 citations Open access
Semantic Scholar
Large-Scale Proteomic Assessment of Urinary Extracellular Vesicles Highlights Their Reliability in Reflecting Protein Changes in the Kidney
Qi Wu, S. Poulsen, S. Murali, Paul Grimm +5 more
2021Journal of the American Society of Nephrology45 citations Open access
Semantic Scholar
Rapid Aldosterone-Mediated Signaling in the DCT Increases Activity of the Thiazide-Sensitive NaCl Cotransporter.
Lei Cheng, S. Poulsen, Qi Wu, C. Esteva-Font +8 more
2019Journal of the American Society of Nephrology45 citations Open access
Semantic Scholar
Aquaporin-2 membrane targeting: still a conundrum.
E. Olesen, R. Fenton
2017AJP - Renal Physiology44 citations Open access
Semantic Scholar
Proximal tubule transferrin uptake is modulated by cellular iron and mediated by apical membrane megalin–cubilin complex and transferrin receptor 1
Craig P. Smith, Wing-Kee Lee, M. Haley, S. Poulsen +2 more
2019Journal of Biological Chemistry41 citations Open access
Semantic Scholar
Advances in Aquaporin-2 trafficking mechanisms and their implications for treatment of water balance disorders.
R. Fenton, S. Murali, H. Moeller
2020American Journal of Physiology - Cell Physiology35 citations
Semantic Scholar
NaCl cotransporter abundance in urinary vesicles is increased by calcineurin inhibitors and predicts thiazide sensitivity
Omar A Z Tutakhel, A. Moes, Marco A Valdez-Flores, Marleen L. A. Kortenoeven +8 more
2017PLoS ONE35 citations Open access
Semantic Scholar
Pharmacological Npt2a Inhibition Causes Phosphaturia and Reduces Plasma Phosphate in Mice with Normal and Reduced Kidney Function.
L. Thomas, Jianxiang Xue, S. Murali, R. Fenton +2 more
2019Journal of the American Society of Nephrology33 citations Open access
Semantic Scholar
An inducible intestinal epithelial cell-specific NHE3 knockout mouse model mimicking congenital sodium diarrhea
Jianxiang Xue, L. Thomas, M. Tahmasbi, Alexandra Valdez +3 more
2020Clinical science31 citations Open access
Semantic Scholar
University of Southern Denmark Regulation of the Water Channel Aquaporin-2 via 14-3-3 θ and
H. Moeller, Joachim Slengerik-Hansen, Takwa S. Aroankins, Mette Assentoft +4 more
201627 citations
Semantic Scholar
Protein Phosphatase 1 Inhibitor-1 Mediates the cAMP-Dependent Stimulation of the Renal NaCl Cotransporter.
D. Pentón, S. Moser, Agnieszka Wengi, Jan Czogalla +7 more
2019Journal of the American Society of Nephrology25 citations Open access
Semantic Scholar
RNA sequencing of kidney distal tubule cells reveals multiple mediators of chronic aldosterone action.
S. Poulsen, Kavee Limbutara, R. Fenton, T. Pisitkun +1 more
2018Physiological Genomics25 citations Open access
Semantic Scholar
Dissociation of sodium-chloride cotransporter expression and blood pressure during chronic high dietary potassium supplementation
Robert Little, S. Murali, S. Poulsen, P. Grimm +7 more
2023JCI Insight24 citations Open access
Semantic Scholar
Cryo‐EM structure of the human NKCC1 transporter reveals mechanisms of ion coupling and specificity
C. Neumann, Lena Lindtoft Rosenbæk, R. K. Flygaard, M. Habeck +8 more
2021bioRxiv24 citations Open access
Semantic Scholar
K+ and the renin–angiotensin–aldosterone system: new insights into their role in blood pressure control and hypertension treatment
S. Poulsen, R. Fenton
2019Journal of Physiology23 citations
Semantic Scholar
Role of adenylyl cyclase 6 in the development of lithium-induced nephrogenic diabetes insipidus.
S. Poulsen, T. B. Kristensen, H. Brooks, D. Kohan +2 more
2017JCI Insight22 citations Open access
Semantic Scholar
High dietary potassium causes ubiquitin-dependent degradation of the kidney sodium-chloride cotransporter
Marleen L. A. Kortenoeven, C. Esteva-Font, H. Dimke, S. Poulsen +2 more
2021Journal of Biological Chemistry21 citations Open access
Semantic Scholar
Dysregulation of Principal Cell miRNAs Facilitates Epigenetic Regulation of AQP2 and Results in Nephrogenic Diabetes Insipidus
Federica Petrillo, A. Iervolino, T. Angrisano, S. Jelen +13 more
2021Journal of the American Society of Nephrology21 citations Open access
Semantic Scholar
Activation of the metabolic sensor AMP-activated protein kinase inhibits aquaporin-2 function in kidney principal cells.
M. Al-Bataineh, Hui Li, K. Ohmi, F. Gong +9 more
2016AJP - Renal Physiology21 citations Open access
Semantic Scholar
The murine choroid plexus epithelium expresses the 2Cl-/H+ exchanger ClC-7 and Na+/H+ exchanger NHE6 in the luminal membrane domain.
H. Damkier, Henriette L. Christensen, I. B. Christensen, Qi Wu +2 more
2018American Journal of Physiology - Cell Physiology20 citations
Semantic Scholar
Deletion of the serine protease CAP2/Tmprss4 leads to dysregulated renal water handling upon dietary potassium depletion
A. Keppner, Darko Maric, C. Sergi, Camille Ansermet +9 more
2019Scientific Reports18 citations Open access
Semantic Scholar
The thiazide sensitive sodium chloride co-transporter NCC is modulated by site-specific ubiquitylation
L. L. Rosenbaek, Federica Rizzo, Qi Wu, Lorena Rojas-vega +4 more
2017Scientific Reports18 citations Open access
Semantic Scholar
Impaired Mineral Ion Metabolism in a Mouse Model of Targeted Calcium-Sensing Receptor (CaSR) Deletion from Vascular Smooth Muscle Cells
M. Schepelmann, M. Ranieri, I. Lopez-Fernandez, T. Webberley +21 more
2022Journal of the American Society of Nephrology16 citations Open access
Semantic Scholar
Enhanced phosphate absorption in intestinal epithelial cell‐specific NHE3 knockout mice
Jianxiang Xue, L. Thomas, S. Murali, Moshe Levi +3 more
2022Acta Physiologica16 citations Open access
Semantic Scholar
Renal Denervation and CD161a Immune Ablation Prevent Cholinergic Hypertension and Renal Sodium Retention.
Nandita S. Raikwar, Cameron L. Braverman, Peter M. Snyder, R. Fenton +3 more
2019American Journal of Physiology. Heart and Circulatory Physiology16 citations Open access
Semantic Scholar
Functional assessment of sodium chloride cotransporter NCC mutants in polarized mammalian epithelial cells.
L. L. Rosenbaek, Federica Rizzo, N. MacAulay, O. Staub +1 more
2017AJP - Renal Physiology16 citations Open access
Semantic Scholar
Activation of the kidney sodium chloride cotransporter by the β2-adrenergic receptor agonist salbutamol increases blood pressure.
S. Poulsen, Lei Cheng, D. Pentón, Marleen L. A. Kortenoeven +5 more
2021Kidney International15 citations Open access
Semantic Scholar
Autoantibodies Targeting a Collecting Duct-Specific Water Channel in Tubulointerstitial Nephritis.
N. Landegren, Mina Pourmousa Lindberg, J. Skov, Å. Hallgren +17 more
2016Journal of the American Society of Nephrology15 citations Open access
Semantic Scholar
Using human urinary extracellular vesicles to study physiological and pathophysiological states and regulation of the sodium chloride cotransporter
A. Wu, M. Wolley, R. Fenton, M. Stowasser
2022Frontiers in Endocrinology14 citations Open access
Semantic Scholar
The Deubiquitylase USP4 Interacts with the Water Channel AQP2 to Modulate Its Apical Membrane Accumulation and Cellular Abundance
S. Murali, Takwa S. Aroankins, H. Moeller, R. Fenton
2019Cells14 citations Open access
Semantic Scholar
Adenylyl cyclase 6 is required for maintaining acid–base homeostasis
S. Poulsen, C. D. de Evsikova, S. Murali, J. Praetorius +3 more
2018Clinical science14 citations Open access
Semantic Scholar
Temporal deletion of Aqp11 in mice is linked to the severity of cyst-like disease.
Michael Rützler, A. Rojek, M. Damgaard, A. Andreasen +2 more
2017AJP - Renal Physiology14 citations
Semantic Scholar
Randomized Trial on the Effect of Oral Potassium Chloride Supplementation on the Thiazide-Sensitive Sodium Chloride Cotransporter in Healthy Adults
A. Wu, M. Wolley, Hannah L. Mayr, Lei Cheng +8 more
2023Kidney International Reports13 citations Open access
Semantic Scholar
Potassium Effects on NCC Are Attenuated during Inhibition of Cullin E3–Ubiquitin Ligases
S. Murali, Robert Little, S. Poulsen, Mohammed Z. Ferdaus +3 more
2021bioRxiv13 citations Open access
Semantic Scholar
The Cl−/HCO3− exchanger pendrin is downregulated during oral co-administration of exogenous mineralocorticoid and KCl in patients with primary aldosteronism
A. Wu, M. Wolley, Qi Wu, R. Gordon +2 more
2020Journal of Human Hypertension13 citations
Semantic Scholar
Dissecting the Effects of Aldosterone and Hypokalemia on the Epithelial Na+ Channel and the NaCl Cotransporter
M. Kristensen, R. Fenton, S. Poulsen
2022Frontiers in Physiology12 citations Open access
Semantic Scholar
Genetic disruption of slc4a10 alters the capacity for cellular metabolism and vectorial ion transport in the choroid plexus epithelium
I. B. Christensen, Qi Wu, A. S. Bohlbro, M. Skals +4 more
2020Fluids and Barriers of the CNS12 citations Open access
Semantic Scholar
Adenylyl cyclase 6 expression is essential for cholera toxin-induced diarrhea.
R. Fenton, S. Murali, I. Kaji, Y. Akiba +5 more
2019Journal of Infectious Diseases12 citations Open access
Semantic Scholar
The nuclear factor of activated T cells 5 (NFAT5) contributes to the renal corticomedullary differences in gene expression
Dmitry Chernyakov, A. Fischer, Max Brandau, Federica Petrillo +2 more
2022Scientific Reports11 citations Open access
Semantic Scholar
Genetic deletion of the nuclear factor of activated T cells 5 in collecting duct principal cells causes nephrogenic diabetes insipidus
Federica Petrillo, Dmitry Chernyakov, C. Esteva-Font, S. Poulsen +2 more
2022The FASEB Journal10 citations Open access
Semantic Scholar
Molecular characterization of an aquaporin-2 mutation causing a severe form of nephrogenic diabetes insipidus
Emel Saglar Ozer, H. Moeller, T. Karaduman, R. Fenton +1 more
2019Cellular and Molecular Life Sciences10 citations
Semantic Scholar

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