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H. Yousaf · SciRah

Researcher profile · Semantic Scholar

H. Yousaf

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H. Yousaf — researcher profile on SciRah

h-index: 4
Works: 7
Citations: 130

Most-cited papers

Coinhibition of the deubiquitinating enzymes, USP14 and UCHL5, with VLX1570 is lethal to ibrutinib- or bortezomib-resistant Waldenstrom macroglobulinemia tumor cells
A. Paulus, Sharoon Akhtar, T. Caulfield, K. Samuel +18 more
2016Blood Cancer Journal61 citations Open access
Semantic Scholar
Waldenstrom macroglobulinemia cells devoid of BTKC481S or CXCR4WHIM-like mutations acquire resistance to ibrutinib through upregulation of Bcl-2 and AKT resulting in vulnerability towards venetoclax or MK2206 treatment
A. Paulus, Sharoon Akhtar, H. Yousaf, Alak Manna +11 more
2017Blood Cancer Journal54 citations Open access
Semantic Scholar
Drug Resistance Alters CD38 Expression and in Vitro Response to Daratumumab in Waldenstrom Macroglobulinemia Cells
A. Paulus, Sharoon Akhtar, Yamima Bashir, Shumail M. Paulus +6 more
20165 citations
Semantic Scholar
Aurora Kinase Is a Therapeutic Target in Ibrutinib-Resistant Waldenstrom Macroglobulinemia: In-Silico Target Identification and in-Vitro Validation
A. Paulus, Kasyapa S. Chitta, Sharoon Akhtar, H. Yousaf +11 more
20155 citations
Semantic Scholar
VLX1570, a First in Class Dub Inhibitor, Modulates BCR Signaling and CXCR4 Expression and Demonstrates Significant In Vivo Antitumor Activity in a Murine Model of Human Waldenstrom Macroglobulinemia
A. Paulus, Sharoon Akhtar, K. Samuel, H. Yousaf +18 more
20153 citations
Semantic Scholar
Identification of USP14 and UCHL5 As Druggable Oncotargets in Ibrutinib-Resistant Mantle Cell Lymphoma
A. Paulus, Sharoon Akhtar, K. Samuel, H. Yousaf +10 more
20152 citations
Semantic Scholar
Induction of Resistance to Proteasome Inhibition Preferentially Switches Survival Dependence from Bcl-2 to XIAP in Preclinical Models of Waldenstrom Macroglobulinemia: Pre-Clinical Rationale for Early Clinical Sequencing of ABT199
Sharoon Akhtar, A. Paulus, K. Samuel, H. Yousaf +8 more
20150 citations
Semantic Scholar

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A. Paulus — researcher profile on SciRah
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