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Alak Manna · SciRah

Researcher profile · Semantic Scholar

Alak Manna

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Alak Manna — researcher profile on SciRah

h-index: 16
Works: 52
Citations: 746

Most-cited papers

Andrographolide Analogue Induces Apoptosis and Autophagy Mediated Cell Death in U937 Cells by Inhibition of PI3K/Akt/mTOR Pathway
Deepak Kumar, Bimolendu Das, Rupashree Sen, Priyanka Kundu +5 more
2015PLoS ONE66 citations Open access
Semantic Scholar
RETRACTED: Berberine Chloride Mediates Its Anti-Leishmanial Activity via Differential Regulation of the Mitogen Activated Protein Kinase Pathway in Macrophages
Piu Saha, S. Bhattacharjee, Avijit Sarkar, Alak Manna +2 more
2011PLoS ONE62 citations Open access
Semantic Scholar
Novel fluorinated curcuminoids and their pyrazole and isoxazole derivatives: Synthesis, structural studies, Computational/Docking and in-vitro bioassay
K. Laali, William J. Greves, Sebastian J. Correa-Smits, Angela T. Zwarycz +5 more
201861 citations Open access
Semantic Scholar
Waldenstrom macroglobulinemia cells devoid of BTKC481S or CXCR4WHIM-like mutations acquire resistance to ibrutinib through upregulation of Bcl-2 and AKT resulting in vulnerability towards venetoclax or MK2206 treatment
A. Paulus, Sharoon Akhtar, H. Yousaf, Alak Manna +11 more
2017Blood Cancer Journal54 citations Open access
Semantic Scholar
Lisaftoclax (APG-2575) is a Novel BCL-2 Inhibitor with Robust Antitumor Activity in Preclinical Models of Hematologic Malignancy.
Jing Deng, A. Paulus, Douglas D. Fang, Alak Manna +28 more
2022Clinical Cancer Research49 citations Open access
Semantic Scholar
Myeloid derived suppressor cells (MDSCs) can induce the generation of Th17 response from naïve CD4+ T cells.
S. Chatterjee, S. Das, Paramita Chakraborty, Alak Manna +2 more
2013Immunobiology47 citations Open access
Semantic Scholar
Malabaricone-A Induces A Redox Imbalance That Mediates Apoptosis in U937 Cell Line
Alak Manna, Piu Saha, Avijit Sarkar, Debanjan Mukhopadhyay +5 more
2012PLoS ONE43 citations Open access
Semantic Scholar
Allylpyrocatechol Attenuates Collagen-Induced Arthritis via Attenuation of Oxidative Stress Secondary to Modulation of the MAPK, JAK/STAT, and Nrf2/HO-1 Pathways
Soumita De, Alak Manna, S. Kundu, Sritama De Sarkar +4 more
2017Journal of Pharmacology and Experimental Therapeutics35 citations Open access
Semantic Scholar
Evaluation of serological markers to monitor the disease status of Indian post kala-azar dermal leishmaniasis.
Debanjan Mukhopadhyay, N. Das, Sritama De Sarkar, Alak Manna +5 more
2012Transactions of the Royal Society of Tropical Medicine and Hygiene35 citations
Semantic Scholar
Targeting CD38 is lethal to Breg-like chronic lymphocytic leukemia cells and Tregs, but restores CD8+ T-cell responses.
Alak Manna, Timothy M. Kellett, Sonikpreet Aulakh, Laura J. Lewis-Tuffin +11 more
2020Blood Advances34 citations Open access
Semantic Scholar
Targeting CD38 enhances the antileukemic activity of ibrutinib in chronic lymphocytic leukemia (CLL).
Alak Manna, Sonikpreet Aulakh, Prachi Jani, Salman Ahmed +13 more
2019Clinical Cancer Research32 citations Open access
Semantic Scholar
The variable chemotherapeutic response of Malabaricone-A in leukemic and solid tumor cell lines depends on the degree of redox imbalance.
Alak Manna, Sritama De Sarkar, Soumita De, A. K. Bauri +2 more
2015Phytomedicine31 citations
Semantic Scholar
The Antioxidant Activity of Allylpyrocatechol is Mediated via Decreased Generation of Free Radicals Along With Escalation of Antioxidant Mechanisms
D. Sarkar, S. Kundu, Soumita De, Chellaram Hariharan +4 more
2013Phytotherapy Research20 citations
Semantic Scholar
Targeting CD38 with daratumumab is lethal to Waldenström macroglobulinaemia cells
A. Paulus, Alak Manna, Sharoon Akhtar, Shumail M. Paulus +13 more
2018British Journal of Haematology19 citations Open access
Semantic Scholar
Translational development of a novel BAFF-R CAR-T therapy targeting B-cell lymphoid malignancies
Yan Luo, Yaqing Qie, Martha E. Gadd, Alak Manna +8 more
2023Cancer Immunology and Immunotherapy18 citations Open access
Semantic Scholar
Survival trends in glioblastoma and association with treating facility volume
Sonikpreet Aulakh, M. Dedeo, J. Free, S. Rosenfeld +6 more
2019Journal of clinical neuroscience17 citations Open access
Semantic Scholar
Synthesis, Computational Docking Study, and Biological Evaluation of a Library of Heterocyclic Curcuminoids with Remarkable Antitumor Activity
K. Laali, William J. Greves, Angela T. Zwarycz, Sebastian J. Correa-Smits +8 more
2018ChemMedChem14 citations Open access
Semantic Scholar
Influence of polymorphisms in TNF-α and IL1β on susceptibility to alcohol induced liver diseases and therapeutic potential of miR-124-3p impeding TNF-α/IL1β mediated multi-cellular signaling in liver microenvironment
Debanjali Dasgupta, Suchandrima Ghosh, Indrashish Dey, Swagata Majumdar +13 more
2023Frontiers in Immunology13 citations Open access
Semantic Scholar
Impact of MAPK and PI3K/AKT signaling pathways on Malabaricone-A induced cytotoxicity in U937, a histiocytic lymphoma cell line.
Alak Manna, Sritama De Sarkar, Soumita De, A. K. Bauri +2 more
2016International Immunopharmacology13 citations
Semantic Scholar
Oncogenic potential of hepatitis B virus subgenotype D1 surpasses D3: significance in the development of hepatocellular carcinoma
Debanjali Dasgupta, Somenath Datta, Alak Manna, S. Datta +5 more
2016Carcinogenesis12 citations
Semantic Scholar
Prospect of CAR T-cell therapy in acute myeloid leukemia
Talha Badar, Alak Manna, Martha E. Gadd, M. Kharfan-Dabaja +1 more
2022Expert Opinion on Investigational Drugs8 citations
Semantic Scholar
AT-101 Enhances the Antitumor Activity of Lenalidomide in Patients with Multiple Myeloma
S. Ailawadhi, Ricardo D. Parrondo, Navnita Dutta, Bing Han +17 more
2023Cancers7 citations Open access
Semantic Scholar
Regulating the regulators via targeting CD38 in the tumor microenvironment
Navnita Dutta, N. Halder, E. Chini, Sungjune Kim +1 more
2026Frontiers in Immunology6 citations Open access
Semantic Scholar
Generation of Redox Imbalance Mediates the Cytotoxic Effect of Malabaricone-A in a Multidrug Resistant Cell Line.
Alak Manna, A. K. Bauri, S. Chattopadhyay, M. Chatterjee
2015Anti-Cancer Agents in Medicinal Chemistry6 citations
Semantic Scholar
SIRT2-mediated deacetylation of LCK governs the magnitude of T cell receptor signaling
I. Hamaidi, P. Cheng, S. Jun, Alak Manna +17 more
2026Nature Immunology5 citations Open access
Semantic Scholar
Novel tumor-targeted liposomes comprised of an MDM2 antagonist plus proteasome inhibitor display anti-tumor activity in a xenograft model of bortezomib-resistant Waldenstrom macroglobulinemia
V. Madamsetty, A. Paulus, Sharoon Akhtar, Alak Manna +4 more
2020Leukemia and Lymphoma5 citations
Semantic Scholar
CD38 Targeted Therapy in Glioblastoma: A Step Forward. (P4.160)
Sonikpreet, P. Schiapparelli, Alak Manna, A. Paulus +3 more
2018Neurology5 citations
Semantic Scholar
A study of the free radical scavenging effects of Piper betle leaf extract in patients with vitiligo
Sneha Mitra, A. Pati, Alak Manna, A. Ghosh +3 more
2017Indian Journal of Dermatology, Venereology and Leprology5 citations Open access
Semantic Scholar
Phase I Study of a Novel Bcl-2 Inhibitor, at-101 in Combination with Lenalidomide and Dexamethasone in Patients with Relapsed and/or Refractory Multiple Myeloma (RRMM)
S. Ailawadhi, Victoria R. Alegria, Salman Ahmed, B. Laplant +9 more
2019Blood4 citations Open access
Semantic Scholar
CD38hi B-regulatory (B-reg) cells maintain pathological immune tolerance in chronic lymphocytic leukemia (CLL)/B cell diseases: Potential therapeutic considerations
Alak Manna, Sonikpreet Aulakh, T. Sher, S. Ailawadhi +2 more
2019Journal of Immunology3 citations
Semantic Scholar
Using anti-CD38 immunotherapy to enhance anti-tumor T-cell immunity in chronic lymphocytic leukemia (CLL)
Alak Manna, Laura J. Lewis-Tuffin, S. Ailawadhi, A. Chanan-Khan +1 more
2018Journal of Immunology3 citations
Semantic Scholar
Daratumumab Decreases Treg-Mediated Immunosuppression and Potentiates CD8+ T-Cell-Induced Killing of Chronic Lymphocytic Leukemia (CLL) Cells Ex Vivo
Alak Manna, Sharoon Akhtar, Paul Yi, S. Parikh +8 more
20173 citations
Semantic Scholar
Translational development of BAFF-R-specific chimeric antigen receptor T-cell therapy targeting B-cell lymphoid malignancies.
Yan Luo, Yaqing Qie, Martha E. Gadd, Alak Manna +6 more
2023Journal of Clinical Oncology2 citations Open access
Semantic Scholar
Effectiveness of malabaricone-A in P-glycoprotein over-expressing cancer cell lines
Nafisha Yasmin, Alak Manna, S. Sarkar, Chandrakana Bandyopadhyay +3 more
2019International Journal of Basic & Clinical Pharmacology2 citations Open access
Semantic Scholar
Anti-tumor effect of fruit rind of Myristica malabarica in an Ehrlich ascites carcinoma model
Chandrakana Bandyopadhyay, Alak Manna, Soumita De, Nafisha Yasmin +3 more
2019International Journal of Basic & Clinical Pharmacology2 citations Open access
Semantic Scholar
CD38-targeted therapy in glioblastoma: A step forward.
Sonikpreet Aulakh, Alak Manna, P. Schiapparelli, S. Ailawadhi +4 more
20182 citations
Semantic Scholar
Therapeutic targeting of CD38 enhances temozolomide activity in glioblastoma cells and modulates their tumor microenvironment by eliciting an enhanced CD8+ T cell response
Alak Manna, Sonikpreet Aulakh, A. Chanan-Khan, A. Paulus
2020Journal of Immunology1 citations
Semantic Scholar
Phase I Trial of Ibrutinib, Lenalidomide and Dexamethasone in Patients with Relapsed and/or Refractory Multiple Myeloma (RRMM)
S. Ailawadhi, A. Paulus, Victoria R. Alegria, B. Laplant +10 more
2019Blood1 citations Open access
Semantic Scholar
EXTH-06. CD38-TARGETED THERAPY IN GLIOBLASTOMA
Sonikpreet Aulakh, Alak Manna, P. Schiapparelli, S. Ailawadhi +4 more
2018Neuro-Oncology1 citations Open access
Semantic Scholar
Comparative Analysis of Gene Expression Status to Predict Response to Initial Multiple Myeloma Treatment: Utility of the Mmrf Commpass Database in Validating Historical Findings
A. Paulus, Marie V. Coignet, Alak Manna, Mayank Sharma +4 more
20171 citations
Semantic Scholar
The Oral Proteasome Inhibitor Ixazomib, Alone and in Combination with Ibrutinib, Induces Lethality in Waldenstrom Macroglobulinemia Cells That Are Resistant to Ibrutinib
A. Paulus, Alak Manna, Sharoon Akhtar, N. Singh +13 more
20171 citations
Semantic Scholar
Plant-Derived Prooxidants as Potential Anticancer Therapeutics
Alak Manna, S. Chattopadhyay, M. Chatterjee
20161 citations
Semantic Scholar
Editorial: Community series in the regulation of the host immune activation in respiratory virus infections, volume II
Alak Manna, Chung-Guei Huang, Mitali Chatterjee, Ching-Tai Huang +1 more
2025Frontiers in Immunology0 citations Open access
Semantic Scholar
Lenolidamide and IL-15 enhance natural killer cell-mediated immunity and augments the anti-tumor effect of an anti-CD30/CD16A bispecific antibody against Hodgkin’s lymphoma B-cells
Alak Manna, Sonikpreet Aulakh, S. Ailawadhi, A. Chanan-Khan +2 more
2019Journal of Immunology0 citations
Semantic Scholar
Computational Modelling of Multiple Myeloma Patient Genomic Signatures to Predict Treatment Outcome
A. Paulus, Prachi Jani, Salman Ahmed, Sonikpreet Aulakh +14 more
2018Blood0 citations
Semantic Scholar
Front Cover: Synthesis, Computational Docking Study, and Biological Evaluation of a Library of Heterocyclic Curcuminoids with Remarkable Antitumor Activity (ChemMedChem 18/2018)
K. Laali, William J. Greves, Angela T. Zwarycz, Sebastian J. Correa-Smits +8 more
2018ChemMedChem0 citations Open access
Semantic Scholar
Comparative Analysis on the Anti-Tumor Activity of Venetoclax and Obinutuzumab (VO) Versus Venetoclax and Rituximab (VR) in Primary CLL Cells, Ex Vivo
M. Iqbal, Aarushi Sharma, Alak Manna, Sharoon Akhtar +4 more
2018Blood0 citations Open access
Semantic Scholar
Daratumumab Mitigates B-Cell Receptor Signaling and Enhances Antitumor Activity of Ibrutinib in Chronic Lymphocytic Leukemia (CLL) Cells
Alak Manna, Sharoon Akhtar, Zahara Meghji, K. Bhatia +10 more
20170 citations
Semantic Scholar
Targeting CD38 with Daratumumab Suppresses B-Cell Receptor Signaling and Enhances the Activity of Ibrutinib in Waldenstrom Macroglobulinemia Cells
A. Paulus, Alak Manna, Sharoon Akhtar, T. Sher +7 more
20170 citations
Semantic Scholar
microRNA-124 Ameliorates Alcohol Induced Liver Injury by Restricting Multiple Components Involved in Intracellular Crosstalk
Debanjali Dasgupta, Alak Manna, Somenath Datta, Alip Ghosh +6 more
20160 citations
Semantic Scholar

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A. Paulus×27
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A. Paulus — researcher profile on SciRah
A. Chanan-Khan×27
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A. Chanan-Khan — researcher profile on SciRah
S. Ailawadhi×18
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S. Ailawadhi — researcher profile on SciRah
M. Chatterjee×16
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M. Chatterjee — researcher profile on SciRah

×14

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T. Sher — researcher profile on SciRah

Sharoon Akhtar×11

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Sharoon Akhtar — researcher profile on SciRah

Sonikpreet Aulakh×10

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Sonikpreet Aulakh — researcher profile on SciRah

S. Chattopadhyay×9

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V. Roy — researcher profile on SciRah

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A. K. Bauri — researcher profile on SciRah

Victoria R. Alegria×6

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Victoria R. Alegria — researcher profile on SciRah

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Soumita De — researcher profile on SciRah