Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

J. Stavnezer · SciRah

Researcher profile · Semantic Scholar

J. Stavnezer

Share profile

J. Stavnezer — researcher profile on SciRah

h-index: 52
Works: 150
Citations: 8,816

Most-cited papers

Mechanism and regulation of class switch recombination.
J. Stavnezer, J. Guikema, C. E. Schrader
2008Annual Review of Immunology1,158 citations Open access
Semantic Scholar
Interaction and Functional Cooperation of PEBP2/CBF with Smads
J. Hanai, Lin-Feng Chen, T. Kanno, N. Ohtani‐Fujita +10 more
1999Journal of Biological Chemistry467 citations Open access
Semantic Scholar
Ig heavy chain class switch recombination: mechanism and regulation
J. Stavnezer, C. E. Schrader
2014Journal of Immunology257 citations Open access
Semantic Scholar
Reduced Isotype Switching in Splenic B Cells from Mice Deficient in Mismatch Repair Enzymes
C. E. Schrader, W. Edelmann, R. Kucherlapati, J. Stavnezer
1999Journal of Experimental Medicine243 citations Open access
Semantic Scholar
Interaction of Stat6 and NF-κB: Direct Association and Synergistic Activation of Interleukin-4-Induced Transcription
Ching-Hung Shen, J. Stavnezer
1998Molecular and Cellular Biology223 citations Open access
Semantic Scholar
Molecular processes that regulate class switching.
J. Stavnezer
2000Current Topics in Microbiology and Immunology222 citations
Semantic Scholar
Inducible DNA breaks in Ig S regions are dependent on AID and UNG
C. E. Schrader, Erin K. Linehan, Sofia N. Mochegova, R. T. Woodland +1 more
2005Journal of Experimental Medicine205 citations Open access
Semantic Scholar
Evolution of isotype switching.
J. Stavnezer, C. Amemiya
2004Seminars in Immunology188 citations
Semantic Scholar
Role for Mismatch Repair Proteins Msh2, Mlh1, and Pms2 in Immunoglobulin Class Switching Shown by Sequence Analysis of Recombination Junctions
C. E. Schrader, Joycelyn Vardo, J. Stavnezer
2002Journal of Experimental Medicine154 citations Open access
Semantic Scholar
The complex regulation and function of activation-induced cytidine deaminase (AID)
J. Stavnezer
2011Trends in immunology134 citations Open access
Semantic Scholar
APE1- and APE2-dependent DNA breaks in immunoglobulin class switch recombination
J. Guikema, Erin K. Linehan, D. Tsuchimoto, Y. Nakabeppu +3 more
2007Journal of Experimental Medicine117 citations Open access
Semantic Scholar
Mismatch repair converts AID-instigated nicks to double-strand breaks for antibody class-switch recombination.
J. Stavnezer, C. E. Schrader
2006Trends in Genetics111 citations
Semantic Scholar
The Surprising Discovery That TGFβ Specifically Induces the IgA Class Switch
J. Stavnezer, Joonsoo Kang
2009Journal of Immunology107 citations Open access
Semantic Scholar
Activation-induced cytidine deaminase induces reproducible DNA breaks at many non-Ig loci in activated B cells
O. Staszewski, Richard E. Baker, A. Ucher, R. Martier +2 more
2011Molecules and Cells102 citations Open access
Semantic Scholar
Enhanced IgA Class Switching in Marginal Zone and B1 B Cells Relative to Follicular/B2 B Cells1
D. Kaminski, J. Stavnezer
2006Journal of Immunology96 citations
Semantic Scholar
The μ Switch Region Tandem Repeats Are Important, but Not Required, for Antibody Class Switch Recombination
T. Luby, C. E. Schrader, J. Stavnezer, E. Selsing
2001Journal of Experimental Medicine95 citations Open access
Semantic Scholar
APE1- and APE2-dependent DNA breaks in immunoglobulin class switch recombination
J. Guikema, Erin K. Linehan, D. Tsuchimoto, Y. Nakabeppu +3 more
2007Journal of Experimental Medicine89 citations Open access
Semantic Scholar
Activation-Induced Cytidine Deaminase-Dependent DNA Breaks in Class Switch Recombination Occur during G1 Phase of the Cell Cycle and Depend upon Mismatch Repair1
C. E. Schrader, J. Guikema, Erin K. Linehan, E. Selsing +1 more
2007Journal of Immunology87 citations Open access
Semantic Scholar
Mutations occur in the Ig Sμ region but rarely in Sγ regions prior to class switch recombination
C. E. Schrader, S. P. Bradley, Joycelyn Vardo, Sofia N. Mochegova +2 more
2003EMBO Journal83 citations Open access
Semantic Scholar
Mapping of switch recombination junctions, a tool for studying DNA repair pathways during immunoglobulin class switching.
J. Stavnezer, Andréas Björkman, Li-Kun Du, A. Cagigi +1 more
2010Advances in Immunology82 citations
Semantic Scholar
Immunoglobulin genes: generating diversity with AID and UNG.
U. Storb, J. Stavnezer
2002Current Biology78 citations Open access
Semantic Scholar
The Smu tandem repeat region is critical for Ig isotype switching in the absence of Msh2.
Irene M. Min, C. E. Schrader, Joycelyn Vardo, T. Luby +3 more
2003Immunity71 citations Open access
Semantic Scholar
CBF alpha3 (AML2) is induced by TGF-beta1 to bind and activate the mouse germline Ig alpha promoter.
Meng-Jiao Shi, J. Stavnezer
1998Journal of Immunology66 citations
Semantic Scholar
A DNA break– and phosphorylation-dependent positive feedback loop promotes immunoglobulin class-switch recombination
B. Vuong, Kayleigh Herrick-Reynolds, B. Vaidyanathan, Joseph N. Pucella +10 more
2013Nature Immunology65 citations Open access
Semantic Scholar
AID binds cooperatively with UNG and Msh2-Msh6 to Ig switch regions dependent upon the AID C terminus
Sanjay Ranjit, Lyne Khair, Erin K. Linehan, A. Ucher +3 more
2011Journal of Immunology64 citations Open access
Semantic Scholar
Mlh1 Can Function in Antibody Class Switch Recombination Independently of Msh2
C. E. Schrader, Joycelyn Vardo, J. Stavnezer
2003Journal of Experimental Medicine63 citations Open access
Semantic Scholar
Evidence for Class-Specific Factors in Immunoglobulin Isotype Switching
Ananth Shanmugam, Meng-Jiao Shi, Lauren E. Yauch, J. Stavnezer +1 more
2000Journal of Experimental Medicine62 citations Open access
Semantic Scholar
Crosstalk between BRCA-Fanconi anemia and mismatch repair pathways prevents MSH2-dependent aberrant DNA damage responses
Min Peng, Jenny Xie, A. Ucher, J. Stavnezer +1 more
2014EMBO Journal59 citations Open access
Semantic Scholar
DNA polymerase β is able to repair breaks in switch regions and plays an inhibitory role during immunoglobulin class switch recombination
Xiaoming Wu, J. Stavnezer
2007Journal of Experimental Medicine58 citations Open access
Semantic Scholar
Differential Regulation of Mouse Germline Ig γ1 and ε Promoters by IL-4 and CD401
Chunxiao Mao, J. Stavnezer
2001Journal of Immunology58 citations Open access
Semantic Scholar
Differential expression of APE1 and APE2 in germinal centers promotes error-prone repair and A:T mutations during somatic hypermutation
J. Stavnezer, Erin K. Linehan, Mikayla R. Thompson, Ghaith Habboub +5 more
2014Proceedings of the National Academy of Sciences of the United States of America56 citations Open access
Semantic Scholar
Analysis of transforming growth factor‐β1‐induced Ig germ‐line γ2b transcription and its implication for IgA isotype switching
Seok-Rae Park, Goo-Young Seo, A. Choi, J. Stavnezer +1 more
2005European Journal of Immunology54 citations Open access
Semantic Scholar
The roles of APE1, APE2, DNA polymerase β and mismatch repair in creating S region DNA breaks during antibody class switch
C. E. Schrader, J. Guikema, Xiaoming Wu, J. Stavnezer
2009Philosophical Transactions of the Royal Society B: Biological Sciences52 citations Open access
Semantic Scholar
Deletion of the Nucleotide Excision Repair Gene Ercc1 Reduces Immunoglobulin Class Switching and Alters Mutations Near Switch Recombination Junctions
C. E. Schrader, Joycelyn Vardo, Erin K. Linehan, M. Twarog +3 more
2004Journal of Experimental Medicine42 citations Open access
Semantic Scholar
Iα exon-replacement mice synthesize a spliced HPRT–Cα transcript which may explain their ability to switch to IgA. Inhibition of switching to IgG in these mice
Gang Qiu, G. Harriman, J. Stavnezer
199941 citations
Semantic Scholar
Roles of Ets proteins, NF-κB and nocodazole in regulating induction of transcription of mouse germline Ig α RNA by transforming growth factor-β1
Meng-Jiao Shi, Seok-Rae Park, P. Kim, J. Stavnezer
200139 citations Open access
Semantic Scholar
Shifts in targeting of class switch recombination sites in mice that lack μ switch region tandem repeats or Msh2
Irene M. Min, L. Rothlein, C. E. Schrader, J. Stavnezer +1 more
2005Journal of Experimental Medicine36 citations Open access
Semantic Scholar
p53 Represses Class Switch Recombination to IgG2a through its Antioxidant Function
J. Guikema, C. E. Schrader, M. Brodsky, Erin K. Linehan +6 more
2010Journal of Immunology35 citations Open access
Semantic Scholar
Antibody class switching differs among SJL, C57BL/6 and 129 mice.
D. Kaminski, J. Stavnezer
2007International Immunology35 citations
Semantic Scholar
Faculty Opinions recommendation of Uracil DNA glycosylase disruption blocks Ig gene conversion and induces transition mutations.
J. Stavnezer
200633 citations
Semantic Scholar
AID-Initiated Off-Target DNA Breaks are Detected and Resolved During S-Phase
M. Hasham, Kathy J. Snow, Nina M. Donghia, Jane A. Branca +4 more
2012Journal of Immunology32 citations Open access
Semantic Scholar
Activation of the Mouse Ig Germline ε Promoter by IL-4 Is Dependent on AP-1 Transcription Factors1
Ching-Hung Shen, J. Stavnezer
2001Journal of Immunology32 citations Open access
Semantic Scholar
Regulation of the promoter for human immunoglobulin γ3 germ‐line transcription and its interaction with the 3'α enhancer
Q. Pan, C. Petit‐Frére, J. Stavnezer, L. Hammarström
2000European Journal of Immunology32 citations Open access
Semantic Scholar
Switch recombination in a transfected plasmid occurs preferentially in a B cell line that undergoes switch recombination of its chromosomal Ig heavy chain genes.
J. Stavnezer, S. P. Bradley, N. Rousseau, Todd Pearson +4 more
1999Journal of Immunology32 citations Open access
Semantic Scholar
The Histone Methyltransferase Suv39h1 Increases Class Switch Recombination Specifically to IgA1
S. P. Bradley, D. Kaminski, A. H. Peters, T. Jenuwein +1 more
2006Journal of Immunology30 citations Open access
Semantic Scholar
Stimuli that enhance IgA class switching increase histone 3 acetylation at Sα, but poorly stimulate sequential switching from IgG2b
D. Kaminski, J. Stavnezer
2007European Journal of Immunology29 citations Open access
Semantic Scholar
The Ubiquitously Expressed DNA-Binding Protein Late SV40 Factor Binds Ig Switch Regions and Represses Class Switching to IgA1
Elise E. Drouin, C. E. Schrader, J. Stavnezer, U. Hansen
2002Journal of Immunology29 citations Open access
Semantic Scholar
Class Switch Recombination Efficiency and Junction Microhomology Patterns in Msh2-, Mlh1-, and Exo1-Deficient Mice Depend on the Presence of μ Switch Region Tandem Repeats
Jennifer Eccleston, C. E. Schrader, K. Yuan, J. Stavnezer +1 more
2009Journal of Immunology26 citations Open access
Semantic Scholar
Antibody class switching: uncoupling S region accessibility from transcription.
D. Kaminski, J. Stavnezer
2004Trends in Genetics23 citations
Semantic Scholar
A Touch of Antibody Class
J. Stavnezer
2000Science22 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

C. E. Schrader×21
Invite
C. E. Schrader — researcher profile on SciRah
Erin K. Linehan×8
Invite
Erin K. Linehan — researcher profile on SciRah
J. Guikema×7
Invite
J. Guikema — researcher profile on SciRah
Joycelyn Vardo×5
Invite
Joycelyn Vardo — researcher profile on SciRah

×5

Invite

A. Ucher — researcher profile on SciRah

Invite

D. Kaminski — researcher profile on SciRah

Invite

E. Selsing — researcher profile on SciRah

Meng-Jiao Shi×4

Invite

Meng-Jiao Shi — researcher profile on SciRah

D. Tsuchimoto×3

Invite

D. Tsuchimoto — researcher profile on SciRah

Y. Nakabeppu×3

Invite

Y. Nakabeppu — researcher profile on SciRah

S. P. Bradley×3

Invite

S. P. Bradley — researcher profile on SciRah

Ching-Hung Shen×2

Invite

Ching-Hung Shen — researcher profile on SciRah