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Li-Kun Du · SciRah

Researcher profile · Semantic Scholar

Li-Kun Du

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Li-Kun Du — researcher profile on SciRah

h-index: 34
Works: 70
Citations: 3,577

Most-cited papers

Deleterious mutations in LRBA are associated with a syndrome of immune deficiency and autoimmunity.
G. López-Herrera, G. Tampella, Q. Pan-Hammarström, P. Herholz +29 more
2012American Journal of Human Genetics496 citations Open access
Semantic Scholar
Human HOIP and LUBAC deficiency underlies autoinflammation, immunodeficiency, amylopectinosis, and lymphangiectasia
B. Boisson, E. Laplantine, K. Dobbs, A. Cobat +18 more
2015Journal of Experimental Medicine249 citations Open access
Semantic Scholar
Persistence of SARS-CoV-2-specific B and T cell responses in convalescent COVID-19 patients 6–8 months after the infection
Natalia Sherina, A. Piralla, Li-Kun Du, H. Wan +27 more
2020bioRxiv200 citations Open access
Semantic Scholar
Role for Msh5 in the regulation of Ig class switch recombination
Hideharu Sekine, R. Ferreira, Q. Pan-Hammarström, R. Graham +24 more
2007Proceedings of the National Academy of Sciences of the United States of America155 citations Open access
Semantic Scholar
Tumor-infiltrating lymphocytes: Warriors fight against tumors powerfully.
Baisheng Lin, Li-Kun Du, Hongmei Li, Xiao Zhu +2 more
2020Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie149 citations Open access
Semantic Scholar
Heterologous immunization with inactivated vaccine followed by mRNA-booster elicits strong immunity against SARS-CoV-2 Omicron variant
F. Zuo, Hassan Abolhassani, Li-Kun Du, A. Piralla +24 more
2022Nature Communications148 citations Open access
Semantic Scholar
Combined immunodeficiency and Epstein-Barr virus–induced B cell malignancy in humans with inherited CD70 deficiency
Hassan Abolhassani, E. Edwards, A. Ikincioğullari, Huie Jing +29 more
2017Journal of Experimental Medicine143 citations Open access
Semantic Scholar
Reexamining the role of TACI coding variants in common variable immunodeficiency and selective IgA deficiency
Q. Pan-Hammarström, U. Salzer, Li-Kun Du, J. Björkander +8 more
2007Nature Genetics128 citations Open access
Semantic Scholar
piRNAs: biogenesis and their potential roles in cancer
B. Guo, Dong-Pei Li, Li-Kun Du, Xiao Zhu
2020Cancer Metastasis Review122 citations
Semantic Scholar
Characterization of T and B cell repertoire diversity in patients with RAG deficiency
Yu-Nee Lee, Francesco Frugoni, K. Dobbs, I. Tirosh +30 more
2016Science immunology108 citations Open access
Semantic Scholar
Human serum from SARS-CoV-2-vaccinated and COVID-19 patients shows reduced binding to the RBD of SARS-CoV-2 Omicron variant
M. Schubert, F. Bertoglio, Stephan Steinke, P. A. Heine +24 more
2021BMC Medicine93 citations Open access
Semantic Scholar
Mapping of switch recombination junctions, a tool for studying DNA repair pathways during immunoglobulin class switching.
J. Stavnezer, Andréas Björkman, Li-Kun Du, A. Cagigi +1 more
2010Advances in Immunology82 citations
Semantic Scholar
Immunity to SARS-CoV-2 up to 15 months after infection
Harold Marcotte, A. Piralla, F. Zuo, Li-Kun Du +29 more
2021bioRxiv74 citations Open access
Semantic Scholar
EXTL3 mutations cause skeletal dysplasia, immune deficiency, and developmental delay
Stefano Volpi, Y. Yamazaki, Patrick M. Brauer, E. van Rooijen +35 more
2017Journal of Experimental Medicine73 citations Open access
Semantic Scholar
Human T-bet governs the generation of a distinct subset of CD11chighCD21low B cells
Rui Yang, D. Avery, Katherine J. L. Jackson, Masato Ogishi +32 more
2022Science immunology70 citations Open access
Semantic Scholar
Functional analysis of naturally occurring DCLRE1C mutations and correlation with the clinical phenotype of ARTEMIS deficiency
K. Felgentreff, Yu-Nee Lee, Francesco Frugoni, Li-Kun Du +9 more
2015Journal of Allergy and Clinical Immunology70 citations Open access
Semantic Scholar
Non-homologous end joining in class switch recombination: the beginning of the end
A. Kotnis, Li-Kun Du, Chong-Hai Liu, Sergey W. Popov +1 more
2008Philosophical Transactions of the Royal Society B: Biological Sciences69 citations Open access
Semantic Scholar
The H2B deubiquitinase Usp22 promotes antibody class switch recombination by facilitating non-homologous end joining
Cong-Lei Li, Thergiory Irrazabal, Clare C So, M. Berrú +6 more
2018Nature Communications62 citations Open access
Semantic Scholar
Inherited IFNAR1 Deficiency in a Child with Both Critical COVID-19 Pneumonia and Multisystem Inflammatory Syndrome
Hassan Abolhassani, N. Landegren, P. Bastard, M. Materna +20 more
2022Journal of Clinical Immunology60 citations Open access
Semantic Scholar
Novel Mutations in TACI (TNFRSF13B) Causing Common Variable Immunodeficiency
J. Mohammadi, Chong-Hai Liu, A. Aghamohammadi, A. Bergbreiter +8 more
2009Journal of Clinical Immunology59 citations
Semantic Scholar
CD27− B-Cells Produce Class Switched and Somatically Hyper-Mutated Antibodies during Chronic HIV-1 Infection
A. Cagigi, Li-Kun Du, L. Dang, S. Grutzmeier +4 more
2009PLoS ONE57 citations Open access
Semantic Scholar
Cernunnos influences human immunoglobulin class switch recombination and may be associated with B cell lymphomagenesis
Li-Kun Du, Rou-Jun Peng, Andréas Björkman, Noel Filipe de Miranda +16 more
2012Journal of Experimental Medicine50 citations Open access
Semantic Scholar
Disparate roles of ATR and ATM in immunoglobulin class switch recombination and somatic hypermutation
Q. Pan-Hammarström, A. Lähdesmäki, Yao-Feng Zhao, Li-Kun Du +6 more
2006Journal of Experimental Medicine50 citations Open access
Semantic Scholar
A primary immunodeficiency characterized by defective immunoglobulin class switch recombination and impaired DNA repair
Sophie Péron, Q. Pan-Hammarström, K. Imai, Li-Kun Du +9 more
2007Journal of Experimental Medicine49 citations Open access
Semantic Scholar
A regulatory role for the cohesin loader NIPBL in nonhomologous end joining during immunoglobulin class switch recombination
E. Enervald, Li-Kun Du, T. Visnes, Andréas Björkman +16 more
2013Journal of Experimental Medicine48 citations Open access
Semantic Scholar
X-Linked TLR7 Deficiency Underlies Critical COVID-19 Pneumonia in a Male Patient with Ataxia-Telangiectasia
Hassan Abolhassani, Ahmad Vosughimotlagh, Takaki Asano, N. Landegren +16 more
2021Journal of Clinical Immunology45 citations Open access
Semantic Scholar
Conversion of monoclonal IgG to dimeric and secretory IgA restores neutralizing ability and prevents infection of Omicron lineages
H. Marcotte, Y. Cao, F. Zuo, L. Simonelli +41 more
2023bioRxiv44 citations Open access
Semantic Scholar
SARS-CoV-2–specific B- and T-cell immunity in a population-based study of young Swedish adults
S. Björkander, Li-Kun Du, F. Zuo, S. Ekström +13 more
2021Journal of Allergy and Clinical Immunology44 citations Open access
Semantic Scholar
End-joining during Immunoglobulin Class Switch Recombination
Li-Kun Du, M. van der Burg, Sergey W. Popov, A. Kotnis +3 more
43 citations
Semantic Scholar
Screening of functional and positional candidate genes in families with common variable immunodeficiency
U. Salzer, C. Neumann, J. Thiel, C. Woellner +13 more
2008BMC Immunology42 citations Open access
Semantic Scholar
APRIL-dependent life-long plasmacyte maintenance and immunoglobulin production in humans.
Tzu-Wen Yeh, Tsubasa Okano, T. Naruto, Motoi Yamashita +9 more
2020Journal of Allergy and Clinical Immunology38 citations
Semantic Scholar
Modeling altered T-cell development with induced pluripotent stem cells from patients with RAG1-dependent immune deficiencies.
Patrick M. Brauer, Itai M. Pessach, E. Clarke, J. Rowe +19 more
2016Blood38 citations Open access
Semantic Scholar
Differential role of nonhomologous end joining factors in the generation, DNA damage response, and myeloid differentiation of human induced pluripotent stem cells
K. Felgentreff, Li-Kun Du, Katja G. Weinacht, K. Dobbs +14 more
2014Proceedings of the National Academy of Sciences of the United States of America36 citations Open access
Semantic Scholar
Genetic and immunologic evaluation of children with inborn errors of immunity and severe or critical COVID-19
Hassan Abolhassani, S. Delavari, N. Landegren, S. Shokri +19 more
2022Journal of Allergy and Clinical Immunology35 citations Open access
Semantic Scholar
Loss of ZBTB24 impairs nonhomologous end-joining and class-switch recombination in patients with ICF syndrome
A. Helfricht, P. E. Thijssen, Magdalena B. Rother, R. Shah +22 more
2020Journal of Experimental Medicine34 citations Open access
Semantic Scholar
DNA-PKcs Is Involved in Ig Class Switch Recombination in Human B Cells
Andréas Björkman, Li-Kun Du, K. Felgentreff, Cornelia Rosner +8 more
2015Journal of Immunology34 citations Open access
Semantic Scholar
Expression of Helicobacter pylori Virulence Factors and Associated Expression Profiles of Inflammatory Genes in the Human Gastric Mucosa
Si-Cheng Wen, D. Velin, C. Felley, Li-Kun Du +2 more
2007Infection and Immunity32 citations Open access
Semantic Scholar
Three-dimensional genome: developmental technologies and applications in precision medicine
Ying-Qi Li, Tao Tao, Li-Kun Du, Xiao Zhu
2020Journal of Human Genetics27 citations
Semantic Scholar
Genome-wide CRISPR screens reveal synthetic lethal interaction between CREBBP and EP300 in diffuse large B-cell lymphoma
M. Nie, Li-Kun Du, W. Ren, J. Joung +7 more
2021Cell Death and Disease25 citations Open access
Semantic Scholar
Lung function before and after COVID-19 in young adults: A population-based study
I. Mogensen, J. Hallberg, S. Björkander, Li-Kun Du +10 more
2022Journal of Allergy and Clinical Immunology: Global24 citations Open access
Semantic Scholar
SARS-CoV-2 brainstem encephalitis in human inherited DBR1 deficiency
Yi-Hao Chan, Vanja Lundberg, J. Le Pen, Jiayi Yuan +46 more
2024Journal of Experimental Medicine20 citations Open access
Semantic Scholar
Aberrant recombination and repair during immunoglobulin class switching in BRCA1-deficient human B cells
Andréas Björkman, P. Qvist, Li-Kun Du, Margarita Bartish +6 more
2015Proceedings of the National Academy of Sciences of the United States of America19 citations Open access
Semantic Scholar
Genomic characterization of lymphomas in patients with inborn errors of immunity
Xiao-Fei Ye, P. Maglione, C. Wehr, Xiao-Bo Li +23 more
2022Blood Advances18 citations Open access
Semantic Scholar
The dual role of CD70 in B‐cell lymphomagenesis
M. Nie, W. Ren, Xiaofei Ye, M. Berglund +22 more
2022Clinical and Translational Medicine17 citations Open access
Semantic Scholar
A Regulatory Role for NBS1 in Strand-Specific Mutagenesis during Somatic Hypermutation
Li-Kun Du, D. Dunn-Walters, K. Chrzanowska, T. Stankovic +9 more
2008PLoS ONE17 citations Open access
Semantic Scholar
Causative mechanisms and clinical impact of immunoglobulin deficiencies in Ataxia Telangiectasia.
S. Takada, T. J. Weitering, N. V. van Os, Li-Kun Du +8 more
2024Journal of Allergy and Clinical Immunology16 citations Open access
Semantic Scholar
Heterologous immunization with inactivated vaccine followed by mRNA booster elicits strong humoral and cellular immune responses against the SARS-CoV-2 Omicron variant
F. Zuo, Hassan Abolhassani, Li-Kun Du, A. Piralla +25 more
202216 citations
Semantic Scholar
Tumor evolution and immune microenvironment dynamics in primary and relapsed mantle cell lymphoma
Hui Wan, W. Ren, Ming-Yu Yang, M. Nie +20 more
2025Cell Reports Medicine11 citations Open access
Semantic Scholar
Type I Interferon Autoantibodies Correlate With Cellular Immune Alterations in Severe COVID-19
B. Strunz, C. Maucourant, Adi Mehta, H. Wan +80 more
2024Journal of Infectious Diseases7 citations Open access
Semantic Scholar
Orientation Regulation of Class-switch Recombination in Human B Cells.
Li-Kun Du, Valentyn Oksenych, Hui Wan, Xiao-Fei Ye +10 more
2024Journal of Immunology7 citations
Semantic Scholar

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