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E. Schweighoffer · SciRah

Researcher profile · Semantic Scholar

E. Schweighoffer

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E. Schweighoffer — researcher profile on SciRah

h-index: 36
Works: 61
Citations: 9,721

Most-cited papers

Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17
S. Leibundgut-Landmann, O. Gross, M. Robinson, F. Osorio +7 more
2007Nature Immunology1,286 citations Open access
Semantic Scholar
Syk-dependent cytokine induction by Dectin-1 reveals a novel pattern recognition pathway for C type lectins.
N. Rogers, E. Slack, A. D. Edwards, M. Nolte +7 more
2005Immunity979 citations Open access
Semantic Scholar
Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence
O. Gross, H. Poeck, M. Bscheider, Catherine Dostert +9 more
2009Nature957 citations
Semantic Scholar
A novel Syk-dependent mechanism of platelet activation by the C-type lectin receptor CLEC-2.
K. Suzuki-Inoue, Gemma L. J. Fuller, Ángel García, J. Eble +13 more
2006Blood532 citations
Semantic Scholar
Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection
M. Robinson, F. Osorio, Marcela Rosas, Rui P. Freitas +9 more
2009Journal of Experimental Medicine493 citations Open access
Semantic Scholar
Dectin-1 uses novel mechanisms for yeast phagocytosis in macrophages.
J. Herre, Andrew J. Marshall, E. Caron, A. D. Edwards +6 more
2004Blood475 citations Open access
Semantic Scholar
Notch Activity Influences the αβ versus γδ T Cell Lineage Decision
Tracy Washburn, E. Schweighoffer, T. Gridley, David Chang +3 more
1997408 citations Open access
Semantic Scholar
Tyrosine kinase SYK: essential functions for immunoreceptor signalling.
M. Turner, E. Schweighoffer, Francesco Colucci, J. D. Disanto +1 more
2000Immunology today (Amsterdam. Regular ed.)404 citations
Semantic Scholar
Syk kinase is required for collaborative cytokine production induced through Dectin-1 and Toll-like receptors
Kevin M. Dennehy, G. Ferwerda, I. Faro-Trindade, E. Pyż +15 more
2008European Journal of Immunology379 citations Open access
Semantic Scholar
Regulatory T Cells Inhibit Dendritic Cells by Lymphocyte Activation Gene-3 Engagement of MHC Class II1
B. Liang, Craig D. Workman, Jan-Mou Lee, Claude Chew +9 more
2008Journal of Immunology370 citations Open access
Semantic Scholar
Phosphorylation of ASC acts as a molecular switch controlling the formation of speck-like aggregates and inflammasome activity
H. Hara, K. Tsuchiya, I. Kawamura, Rendong Fang +6 more
2013Nature Immunology240 citations Open access
Semantic Scholar
The BAFF Receptor Transduces Survival Signals by Co-opting the B Cell Receptor Signaling Pathway
E. Schweighoffer, Lesley Vanes, J. Nys, D. Cantrell +3 more
2013Immunity220 citations Open access
Semantic Scholar
NKG2D triggers cytotoxicity in mouse NK cells lacking DAP12 or Syk family kinases
S. Zompi, J. Hamerman, K. Ogasawara, E. Schweighoffer +4 more
2003Nature Immunology219 citations
Semantic Scholar
LAT Is Required for Tyrosine Phosphorylation of Phospholipase Cγ2 and Platelet Activation by the Collagen Receptor GPVI
J. Pasquet, B. Gross, L. Quek, N. Asazuma +10 more
1999Molecular and Cellular Biology212 citations Open access
Semantic Scholar
Syk‐dependent ERK activation regulates IL‐2 and IL‐10 production by DC stimulated with zymosan
E. Slack, M. Robinson, Patricia Hernanz-Falcón, Gordon D. Brown +4 more
2007European Journal of Immunology191 citations
Semantic Scholar
Notch activity influences the alphabeta versus gammadelta T cell lineage decision.
Tracy Washburn, E. Schweighoffer, T. Gridley, David Chang +3 more
1997Cell181 citations
Semantic Scholar
Unexpected requirement for ZAP-70 in pre-B cell development and allelic exclusion.
E. Schweighoffer, Lesley Vanes, A. Mathiot, Tetsuya Nakamura +1 more
2003Immunity179 citations Open access
Semantic Scholar
Regulatory T Cells Inhibit Dendritic Cells by Lymphocyte Activation Gene-3 Engagement of MHC Class II
B. Liang, Craig D. Workman, Jan-Mou Lee, Claude Chew +9 more
2008170 citations
Semantic Scholar
CLEC-2 and Syk in the megakaryocytic/platelet lineage are essential for development.
B. Finney, E. Schweighoffer, L. Navarro‐Núñez, C. Bénézech +12 more
2012Blood169 citations Open access
Semantic Scholar
A Critical Role for Syk Protein Tyrosine Kinase in Fc Receptor-Mediated Antigen Presentation and Induction of Dendritic Cell Maturation
C. Sedlik, D. Orbach, Philippe Véron, E. Schweighoffer +9 more
2003Journal of Immunology157 citations Open access
Semantic Scholar
Natural cytotoxicity uncoupled from the Syk and ZAP-70 intracellular kinases
F. Colucci, E. Schweighoffer, E. Tomasello, M. Turner +4 more
2002Nature Immunology146 citations
Semantic Scholar
Restoration of Pattern Recognition Receptor Costimulation to Treat Chromoblastomycosis, a Chronic Fungal Infection of the Skin
Maria da Glória Sousa, Delyth M. Reid, E. Schweighoffer, V. Tybulewicz +6 more
2011Cell Host and Microbe144 citations Open access
Semantic Scholar
Title Phosphorylation of the adaptor ASC acts as a molecular switch that controls the formation of speck-like aggregates and inflammasome activity
H. Hara, K. Tsuchiya, I. Kawamura, Rendong Fang +8 more
2016127 citations
Semantic Scholar
Interaction of Linker for Activation of T Cells with Multiple Adapter Proteins in Platelets Activated by the Glycoprotein VI-selective Ligand, Convulxin*
N. Asazuma, J. Wilde, O. Berlanga, M. Leduc +8 more
2000Journal of Biological Chemistry110 citations Open access
Semantic Scholar
Positive selection of T cells.
B. Fowlkes, E. Schweighoffer
1995Current Opinion in Immunology110 citations
Semantic Scholar
TLR4 signals in B lymphocytes are transduced via the B cell antigen receptor and SYK
E. Schweighoffer, J. Nys, Lesley Vanes, N. Smithers +1 more
2017Journal of Experimental Medicine90 citations Open access
Semantic Scholar
Positive selection is not required for thymic maturation of transgenic gamma delta T cells
E. Schweighoffer, B. Fowlkes
1996Journal of Experimental Medicine72 citations Open access
Semantic Scholar
Syk Tyrosine Kinase Is Critical for B Cell Antibody Responses and Memory B Cell Survival
Jochen A. Ackermann, J. Nys, E. Schweighoffer, S. Mccleary +2 more
2015Journal of Immunology63 citations Open access
Semantic Scholar
Signalling for B cell survival.
E. Schweighoffer, V. Tybulewicz
2018Current Opinion in Cell Biology57 citations Open access
Semantic Scholar
Critical requirement for BCR, BAFF, and BAFFR in memory B cell survival
Jennifer Müller-Winkler, R. Mitter, J. Rappe, Lesley Vanes +4 more
2020Journal of Experimental Medicine56 citations Open access
Semantic Scholar
Redundant role of the Syk protein tyrosine kinase in mouse NK cell differentiation.
F. Colucci, M. Turner, E. Schweighoffer, D. Guy-Grand +4 more
1999Journal of Immunology56 citations
Semantic Scholar
Eosinophils Are An Essential Element Of A Type 2 Immune Axis That Controls Thymus Regeneration
Emilie J. Cosway, Andrea J. White, S. Parnell, E. Schweighoffer +7 more
2022Science immunology51 citations Open access
Semantic Scholar
BAFF signaling in health and disease.
E. Schweighoffer, V. Tybulewicz
2021Current Opinion in Immunology49 citations Open access
Semantic Scholar
Notch Activity Influences the a versus ?d T Cell Lineage Decision
Tracy Washburn, E. Schweighoffer, T. Gridley, David Chang +3 more
199749 citations
Semantic Scholar
Plasmodium-specific atypical memory B cells are short-lived activated B cells
Damián E. Pérez-Mazliah, Peter J. Gardner, E. Schweighoffer, Sarah McLaughlin +6 more
2018eLife45 citations Open access
Semantic Scholar
GPVI Potentiation of Platelet Activation by Thrombin and Adhesion Molecules Independent of Src Kinases and Syk
S. Hughan, C. Hughes, O. McCarty, E. Schweighoffer +4 more
2006Arteriosclerosis, Thrombosis and Vascular Biology44 citations Open access
Semantic Scholar
BAFF activation of the ERK5 MAP kinase pathway regulates B cell survival
E. Jacque, E. Schweighoffer, V. Tybulewicz, S. Ley
2015Journal of Experimental Medicine34 citations Open access
Semantic Scholar
IKK-induced NF-κB1 p105 proteolysis is critical for B cell antibody responses to T cell–dependent antigen
E. Jacque, E. Schweighoffer, Alexander Visekruna, S. Papoutsopoulou +5 more
2014Journal of Experimental Medicine29 citations Open access
Semantic Scholar
Scalable and robust SARS-CoV-2 testing in an academic center
J. Aitken, Karen Ambrose, S. Barrell, R. Beale +282 more
2020Nature Biotechnology26 citations Open access
Semantic Scholar
Redundant role for Zap70 in B cell development and activation
F. Fallah-Arani, E. Schweighoffer, Lesley Vanes, V. Tybulewicz
2008European Journal of Immunology26 citations
Semantic Scholar
A New Look at Syk in αβ and γδ T Cell Development Using Chimeric Mice with a Low Competitive Hematopoietic Environment1
F. Colucci, D. Guy‐grand, Anne Wilson, M. Turner +3 more
2000Journal of Immunology24 citations Open access
Semantic Scholar
Syk-deficient eosinophils show normal interleukin-5-mediated differentiation, maturation, and survival but no longer respond to FcgammaR activation.
Estelle Lach-Trifilieff, Keith Menear, E. Schweighoffer, V. Tybulewicz +1 more
2000Blood22 citations
Semantic Scholar
Rapid CD4 T cell responses to bacterial flagellin require dendritic cell expression of Syk and CARD9
Shaikh M. Atif, Seung-Joo Lee, Lin-xi Li, S. Uematsu +6 more
2014European Journal of Immunology21 citations Open access
Semantic Scholar
Themis2 is not required for B cell development, activation and antibody responses
Harald Hartweger, E. Schweighoffer, Sophia Davidson, M. Peirce +2 more
2014Journal of Immunology18 citations Open access
Semantic Scholar
A new look at Syk in alpha beta and gamma delta T cell development using chimeric mice with a low competitive hematopoietic environment.
F. Colucci, D. Guy‐grand, A. Wilson, M. Turner +3 more
2000Journal of Immunology10 citations
Semantic Scholar
Cytometric analysis of DNA replication inhibited by emetime and cyclosporin A
T. Schweighoffer, E. Schweighoffer, Á. Apáti, Ferenc A. Antoni +3 more
1991Histochemistry10 citations
Semantic Scholar
Usefulness of a flow cytometric analysis of intraplatelet vasodilator-stimulated phosphoprotein phosphorylation for the detection of patients with genetic defects of the platelet P2Y 12 receptor for ADP
K. Suzuki-Inoue, Gemma L. J. Fuller, Ángel García, S. Pöhlmann +21 more
20107 citations
Semantic Scholar
Oncogene expression in thymocytes after emetine treatment of mice.
Tamas Schweighoffer, E. Schweighoffer, Maya Sviresheva, Á. Apáti +4 more
1993Cellular & molecular biology research3 citations
Semantic Scholar
Regulatory T Cells Inhibit Dendritic Cells by Lymphocyte Activation Gene-3 Engagement of MHC Class II 1
B. Liang, Craig D. Workman, Jan-Mou Lee, Claude Chew +9 more
20082 citations
Semantic Scholar
Plasmodium-specific atypical memory B cells are not part of the long-lived memory response
Damián E. Pérez-Mazliah, Peter J. Gardner, E. Schweighoffer, Sarah McLaughlin +6 more
2018bioRxiv1 citations Open access
Semantic Scholar

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