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B. Fowlkes · SciRah

Researcher profile · Semantic Scholar

B. Fowlkes

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B. Fowlkes — researcher profile on SciRah

h-index: 48
Works: 90
Citations: 11K

Most-cited papers

The Journal of Experimental Medicine
Alan N. Houghton, M. Mccarty, Carl F. Nathan, D. Posnett +103 more
20001,921 citations
Semantic Scholar
Selective events in T cell development.
E. Robey, B. Fowlkes
1994Annual Review of Immunology552 citations
Semantic Scholar
Molecular and cellular events of T cell development.
B. Fowlkes, D. Pardoll
1989Advances in Immunology447 citations
Semantic Scholar
Notch Activity Influences the αβ versus γδ T Cell Lineage Decision
Tracy Washburn, E. Schweighoffer, T. Gridley, David Chang +3 more
1997408 citations Open access
Semantic Scholar
Clonal deletion versus clonal anergy: the role of the thymus in inducing self tolerance.
F. Ramsdell, B. Fowlkes
1990Science385 citations
Semantic Scholar
A novel population of T-cell receptor αβ-bearing thymocytes which predominantly expresses a single Vβ gene family
B. Fowlkes, A. M. Kruisbeek, H. Ton-That, M. Weston +3 more
1987Nature354 citations
Semantic Scholar
Differential expression of two distinct T-cell receptors during thymocyte development
D. Pardoll, B. Fowlkes, J. Bluestone, A. Kruisbeek +3 more
1987Nature348 citations
Semantic Scholar
A nondeletional mechanism of thymic self tolerance.
F. Ramsdell, T. Lantz, B. Fowlkes
1989Science309 citations
Semantic Scholar
Early T lymphocytes. Differentiation in vivo of adult intrathymic precursor cells
B. Fowlkes, L. Edison, Bonnie J. Mathieson, T. Chused
1985Journal of Experimental Medicine297 citations Open access
Semantic Scholar
Deletion of self-reactive thymocytes occurs at a CD4+8+ precursor stage
B. Fowlkes, Ronald H. Schwartz, D. Pardoll
1988Nature258 citations
Semantic Scholar
Quantitative Impact of Thymic Clonal Deletion on the T Cell Repertoire
J. V. van Meerwijk, S. Marguerat, R. Lees, Ronald N. Germain +2 more
1997Journal of Experimental Medicine242 citations Open access
Semantic Scholar
MHC class II-specific T cells can develop in the CD8 lineage when CD4 is absent.
Errin O. Matechak, Nigel Killeen, Stephen M. Hedrick, B. Fowlkes
1996Immunity242 citations Open access
Semantic Scholar
Characterization of murine thymocytes with CDS-associated T-cell receptor structures
J. Bluestone, D. Pardoll, S. Sharrow, B. Fowlkes
1987Nature240 citations
Semantic Scholar
Altered development of CD8+ T cell lineages in mice deficient for the Tec kinases Itk and Rlk.
C. Broussard, C. Fleischacker, R. Horai, M. Chetana +5 more
2006Immunity229 citations Open access
Semantic Scholar
Maintenance of in Vivo Tolerance by Persistence of Antigen
F. Ramsdell, B. Fowlkes
1992Science224 citations
Semantic Scholar
Phenotypic, functional, and molecular genetic comparisons of the abnormal lymphoid cells of C3H-lpr/lpr and C3H-gld/gld mice.
W. Davidson, F. Dumont, H. Bedigian, B. Fowlkes +1 more
1986Journal of Immunology224 citations
Semantic Scholar
Thymic selection in CD8 transgenic mice supports an instructive model for commitment to a CD4 or CD8 lineage.
E. Robey, B. Fowlkes, J. Gordon, D. Kioussis +3 more
1991Cell223 citations
Semantic Scholar
Dexamethasone induces irreversible G1 arrest and death of a human lymphoid cell line
J. Harmon, M. Norman, B. Fowlkes, E. Thompson
1979Journal of Cellular Physiology203 citations
Semantic Scholar
Characterization of T cell receptor gamma chain expression in a subset of murine thymocytes.
Andrew M. Lew, D. Pardoll, W. Maloy, B. Fowlkes +6 more
1986Science193 citations
Semantic Scholar
Notch activity influences the alphabeta versus gammadelta T cell lineage decision.
Tracy Washburn, E. Schweighoffer, T. Gridley, David Chang +3 more
1997Cell181 citations
Semantic Scholar
Cell Surface Antigen Expression on Thymocytes: Development and Phenotypic Differentiation of Intrathymic Subsets
Bonnie J. Mathieson, B. Fowlkes
1984Immunological Reviews172 citations
Semantic Scholar
Absence of the Lyt-2-,L3T4+ lineage of T cells in mice treated neonatally with anti-I-A correlates with absence of intrathymic I-A- bearing antigen-presenting cell function
A. Kruisbeek, James J. Mond, B. Fowlkes, J. Carmen +2 more
1985Journal of Experimental Medicine171 citations Open access
Semantic Scholar
A potential role for CD69 in thymocyte emigration.
C. Feng, K. Woodside, B. A. Vance, Dalal El-Khoury +6 more
2002International Immunology160 citations Open access
Semantic Scholar
The majority of CD4+8- thymocytes are functionally immature.
F. Ramsdell, M. Jenkins, Q. Dinh, B. Fowlkes
1991Journal of Immunology157 citations Open access
Semantic Scholar
Premature Expression of T Cell Receptor (Tcr)αβ Suppresses Tcrγδ Gene Rearrangement but Permits Development of γδ Lineage T Cells
Kathleen M. Terrence, C. Pavlovich, Errin O. Matechak, B. Fowlkes
2000Journal of Experimental Medicine148 citations Open access
Semantic Scholar
The level of CD8 expression can determine the outcome of thymic selection.
E. Robey, F. Ramsdell, D. Kioussis, W. Sha +3 more
1992Cell148 citations
Semantic Scholar
Processing of β-Amyloid Precursor-like Protein-1 and -2 by γ-Secretase Regulates Transcription*
M. H. Scheinfeld, Enrico Ghersi, K. Laky, B. Fowlkes +1 more
2002Journal of Biological Chemistry132 citations Open access
Semantic Scholar
Expression of IFN regulatory factor family proteins in lymphocytes. Induction of Stat-1 and IFN consensus sequence binding protein expression by T cell activation.
N. Nelson, Y. Kanno, C. Hong, C. Contursi +12 more
1996Journal of Immunology129 citations
Semantic Scholar
Expression of genes of the T-cell antigen receptor complex in precursor thymocytes
L. Samelson, T. Lindsten, B. Fowlkes, P. J. van den Elsen +4 more
1985Nature127 citations
Semantic Scholar
Preparation of Cells and Reagents for Flow Cytometry
K. Holmes, L. Lantz, B. Fowlkes, I. Schmid +1 more
2001Current Protocols in Immunology119 citations
Semantic Scholar
A Reassessment of the Effect of Activated Notch1 on CD4 and CD8 T Cell Development1
B. Fowlkes, E. Robey
2002Journal of Immunology118 citations
Semantic Scholar
Positive selection of T cells.
B. Fowlkes, E. Schweighoffer
1995Current Opinion in Immunology110 citations
Semantic Scholar
Structural and functional properties of the „hairy”︁ cells of leukemic reticuloendotheliosis
R. Braylan, E. S. Jaffe, T. Triche, K. Nanba +7 more
1978Cancer102 citations Open access
Semantic Scholar
Cell volumes and dna distributions of normal and neoplastic human lymphoid cells
R. Braylan, B. Fowlkes, E. S. Jaffe, S. Sanders +2 more
1978Cancer94 citations Open access
Semantic Scholar
Measurement of DNA content and cell volume in senescent human fibroblasts utilizing flow multiparameter single cell analysis.
E. Schneider, B. Fowlkes
1976Experimental Cell Research91 citations
Semantic Scholar
A novel population of T-cell receptor alpha beta-bearing thymocytes which predominantly expresses a single V beta gene family.
B. Fowlkes, A. Kruisbeek, H. Ton-That, M. Weston +3 more
1987Nature89 citations
Semantic Scholar
Notch signaling in CD4 and CD8 T cell development.
K. Laky, B. Fowlkes
2008Current Opinion in Immunology79 citations Open access
Semantic Scholar
Positive selection is not required for thymic maturation of transgenic gamma delta T cells
E. Schweighoffer, B. Fowlkes
1996Journal of Experimental Medicine72 citations Open access
Semantic Scholar
Constitutive CD8 expression allows inefficient maturation of CD4+ helper T cells in class II major histocompatibility complex mutant mice
E. Robey, Andrea Itano, W. Fanslow, B. Fowlkes
1994Journal of Experimental Medicine70 citations Open access
Semantic Scholar
Engagement of CD4 and CD8 accessory molecules is required for T cell maturation.
F. Ramsdell, B. Fowlkes
1989Journal of Immunology70 citations Open access
Semantic Scholar
Adoptive transfer of CD8+ T cells from immune animals does not transfer immunity to blood stage Plasmodium yoelii malaria.
Joseph M. Vinetz, Sanjai Kumar, M. Good, B. Fowlkes +2 more
1990Journal of Immunology69 citations
Semantic Scholar
Thymus-dependent and thymus-independent developmental pathways for peripheral T cell receptor-gamma delta-bearing lymphocytes.
D. Pardoll, B. Fowlkes, Andrew M. Lew, W. Maloy +5 more
1988Journal of Immunology67 citations Open access
Semantic Scholar
Processing of beta-amyloid precursor-like protein-1 and -2 by gamma-secretase regulates transcription.
M. H. Scheinfeld, Enrico Ghersi, K. Laky, B. Fowlkes +1 more
2002Journal of Biological Chemistry61 citations
Semantic Scholar
Early genetic events in T cell development analyzed by in situ hybridization
D. Pardoll, B. Fowlkes, R. I. Lechler, Ronald N. Germain +1 more
1987Journal of Experimental Medicine61 citations Open access
Semantic Scholar
The αβ versus γδ T-cell lineage choice
E. Robey, B. Fowlkes
199860 citations
Semantic Scholar
Transient rearrangements of the T cell antigen receptor alpha locus in early thymocytes
T. Lindsten, B. Fowlkes, L. Samelson, Mark M. Davis +1 more
1987Journal of Experimental Medicine54 citations Open access
Semantic Scholar
Differential binding of fluorescein-labeled lectins to mouse thymocytes: subsets revealed by flow microfluorometry.
B. Fowlkes, M. Waxdal, S. Sharrow, Charles A. Thomas +2 more
1980Journal of Immunology52 citations
Semantic Scholar
Notch Activity Influences the a versus ?d T Cell Lineage Decision
Tracy Washburn, E. Schweighoffer, T. Gridley, David Chang +3 more
199749 citations
Semantic Scholar
The influence of the thymic environment on the CD4-versus-CD8 T lineage decision
Matilde Canelles, Melissa Park, O. Schwartz, B. Fowlkes
2003Nature Immunology42 citations
Semantic Scholar
The unfolding story of T cell receptor γ
Ew M. Pardoll, A. M. Kruisbeek, B. Fowlkes, J. Coligan +1 more
1987The FASEB Journal41 citations
Semantic Scholar

Frequent co-authors

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E. Robey×7
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E. Robey — researcher profile on SciRah
F. Ramsdell×7
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J. Coligan×7
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D. Pardoll×6
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D. Pardoll — researcher profile on SciRah

E. Schweighoffer

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E. Schweighoffer — researcher profile on SciRah

A. M. Kruisbeek×4

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A. M. Kruisbeek — researcher profile on SciRah

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L. Samelson — researcher profile on SciRah

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D. Pardoll — researcher profile on SciRah

Tracy Washburn×3

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Tracy Washburn — researcher profile on SciRah

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T. Gridley — researcher profile on SciRah

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David Chang — researcher profile on SciRah

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D. Cado — researcher profile on SciRah