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V. Margulets · SciRah

Researcher profile · Semantic Scholar

V. Margulets

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V. Margulets — researcher profile on SciRah

h-index: 17
Works: 36
Citations: 2,517

Most-cited papers

Feeder Layer- and Serum-Free Culture of Human Embryonic Stem Cells1
M. Amit, C. Shariki, V. Margulets, J. Itskovitz-Eldor
2004Biology of Reproduction707 citations
Semantic Scholar
Human Feeder Layers for Human Embryonic Stem Cells1
M. Amit, V. Margulets, H. Segev, K. Shariki +3 more
2003Biology of Reproduction491 citations Open access
Semantic Scholar
Bnip3 mediates doxorubicin-induced cardiac myocyte necrosis and mortality through changes in mitochondrial signaling
Rimpy Dhingra, V. Margulets, S. R. Roy Chowdhury, J. Thliveris +4 more
2014Proceedings of the National Academy of Sciences of the United States of America203 citations Open access
Semantic Scholar
Suspension Culture of Undifferentiated Human Embryonic and Induced Pluripotent Stem Cells
M. Amit, J. Chebath, V. Margulets, Ilana Laevsky +7 more
2010Stem Cell Reviews and Reports158 citations
Semantic Scholar
Mitochondrial autophagy and cell survival is regulated by the circadian Clock gene in cardiac myocytes during ischemic stress
Inna Rabinovich-Nikitin, Mina Rasouli, C. J. Reitz, Illana Posen +6 more
2021Autophagy151 citations Open access
Semantic Scholar
Modulating mitofusins to control mitochondrial function and signaling
Emmanouil Zacharioudakis, B. Agianian, Vasantha Kumar M.V., N. Biris +17 more
2022Nature Communications117 citations Open access
Semantic Scholar
A small-molecule allosteric inhibitor of BAX protects against doxorubicin-induced cardiomyopathy
Dulguun Amgalan, T. Garner, Ryan Pekson, Xiaotong Jia +24 more
2020Nature Cancer115 citations Open access
Semantic Scholar
Ellagic acid antagonizes Bnip3-mediated mitochondrial injury and necrotic cell death of cardiac myocytes.
Abhinav Dhingra, Rahul Jayas, Pegah Afshar, M. Guberman +7 more
2017Free Radical Biology & Medicine100 citations
Semantic Scholar
Reduction of myocardial ischaemia–reperfusion injury by inactivating oxidized phospholipids
C. Yeang, Devin Hasanally, Xu-Chu Que, Ming-Yow Hung +18 more
2018Cardiovascular Research87 citations Open access
Semantic Scholar
p53 Mediates Autophagy and Cell Death by a Mechanism Contingent On Bnip3
E. Wang, H. Gang, Y. Aviv, Rimpy Dhingra +2 more
2013HYPERTENSION78 citations Open access
Semantic Scholar
Proteasomal Degradation of TRAF2 Mediates Mitochondrial Dysfunction in Doxorubicin-Cardiomyopathy.
Rimpy Dhingra, Inna Rabinovich-Nikitin, Sonny M. Rothman, M. Guberman +10 more
2022Circulation66 citations Open access
Semantic Scholar
Impaired NF-κB signalling underlies cyclophilin D-mediated mitochondrial permeability transition pore opening in doxorubicin cardiomyopathy.
Rimpy Dhingra, M. Guberman, Inna Rabinovich-Nikitin, Jonathon Gerstein +5 more
2019Cardiovascular Research57 citations Open access
Semantic Scholar
Bidirectional Regulation of Nuclear Factor-&kgr;B and Mammalian Target of Rapamycin Signaling Functionally Links Bnip3 Gene Repression and Cell Survival of Ventricular Myocytes
Rimpy Dhingra, H. Gang, Yan Wang, Agnieszka K. Biala +4 more
2013Circulation: Heart Failure54 citations Open access
Semantic Scholar
PDK2-mediated alternative splicing switches Bnip3 from cell death to cell survival
H. Gang, Rimpy Dhingra, Jun-Jun Lin, Hai Yan +8 more
2015Journal of Cell Biology37 citations Open access
Semantic Scholar
53 Mediates Autophagy and Cell Death by a Mechanism Contingent On Bnip 3
E. Wang, H. Gang, Y. Aviv, Rimpy Dhingra +2 more
26 citations
Semantic Scholar
Sensory neurons derived from diabetic rats exhibit deficits in functional glycolysis and ATP that are ameliorated by IGF-1
M. Aghanoori, V. Margulets, Darrell R. Smith, L. Kirshenbaum +2 more
2021Molecular Metabolism24 citations Open access
Semantic Scholar
Bcl-2/adenovirus E1B 19-kDa interacting protein (BNip3) has a key role in the mitochondrial dysfunction induced by mutant huntingtin.
F. Sassone, V. Margulets, Annamaria Maraschi, S. Rodighiero +5 more
2015Human Molecular Genetics17 citations
Semantic Scholar
Ellagic acid inhibits mitochondrial fission protein Drp-1 and cell proliferation in cancer
S. Yakobov, Rimpy Dhingra, V. Margulets, Abhinav Dhingra +2 more
2023Molecular and Cellular Biochemistry13 citations
Semantic Scholar
IKKβ stabilizes Mitofusin 2 and suppresses doxorubicin cardiomyopathy.
M. Guberman, Rimpy Dhingra, J. Cross, V. Margulets +3 more
2024Cardiovascular Research9 citations
Semantic Scholar
Retinoic acid-related orphan receptors regulate autophagy and cell survival in cardiac myocytes during hypoxic stress
Eryn Kirshenbaum, Huong Nguyen, V. Margulets, Molly Crandall +2 more
2023The Journal of Cardiovascular Aging6 citations Open access
Semantic Scholar
Molecular Mechanisms Underlying Anthracycline Cardiotoxicity: Challenges in Cardio-Oncology
Rimpy Dhingra, V. Margulets, L. Kirshenbaum
20176 citations Open access
Semantic Scholar
Abstract 23: Disruption of TRAF2-TAK1-NF-κB Signaling Axis Triggers K-48 Linked Poly-Ubiquitylation of RIP1 and Necrotic Cell Death in Doxorubicin Cardiotoxicity
Rimpy Dhingra, V. Margulets, Floribeth Aguilar, L. Kirshenbaum
20151 citations
Semantic Scholar
Circadian disruption exacerbates alcohol-induced cardiac injury through impaired cellular quality control and increased cardiomyocyte death.
Huong Nguyen, Eryn Kirshenbaum, Ruzzell C. Flores, Ben Margulets +12 more
2026Molecular and Cellular Biochemistry0 citations
Semantic Scholar
Abstract Mo020: Loss of TRAF2 Signaling Mediates Mitochondrial Dysfunction in Doxorubicin-Cardiomyopathy
L. Kirshenbaum, Rimpy Dhingra, Inna Rabinovich-Nikitin, H. Gang +3 more
2024Circulation Research0 citations
Semantic Scholar
Abstract P049: Circadian Clock Dysfunction Impairs Mitochondrial Fitness And Contributes To Myocardial Ischemic Injury
Inna Rabinovich-Nikitin, Illana Posen, V. Margulets, T. Martino +1 more
20200 citations
Semantic Scholar
Abstract 734: NF-kB Signaling Regulates Mitochondrial Permeability Transition Pore Opening of Cardiac Myocytes via Cyclophilin D (CypD) Modulation
L. Kirshenbaum, Rimpy Dhingra, M. Guberman, V. Margulets +1 more
2019Circulation Research0 citations
Semantic Scholar
CARDIAC SPHEROIDS AS NOVEL 3D IN VITRO MODELS OF CARDIOTOXICITY
L. Kirshenbaum, Rimpy Dhingra, V. Margulets, Inna Rabinowitz-Nikitin +6 more
20180 citations
Semantic Scholar
Abstract 488: Clock Regulates Autophagy and Cell Survival of Cardiac Myocytes During Hypoxia Stress
Inna Rabinovich-Nikitin, Illana Minuk, V. Margulets, Floribeth Aguilar +2 more
2018Circulation Research0 citations
Semantic Scholar
P2100Bnip3 Displaces Uncoupling Protein3 (UCP3) from cytochrome C oxidase of respiration chain complex IV promoting maladaptive autophagy and necrotic cell death in doxorubicin cardiotoxicity
L. Kirshenbaum, V. Margulets, Rimpy Dhingra, M. Guberman +1 more
20170 citations Open access
Semantic Scholar
Abstract 20933: Regulation of Hypoxia Induced Cardiac Cell Death by the Intrinsic Circadian Clock
L. Kirshenbaum, Inna Rabinovich-Nikitin, H. Gang, V. Margulets +1 more
2017Circulation0 citations
Semantic Scholar
Dual mitophagy and necrosis dependent pathways functionally couple mitochondrial death protein Bnip3 to doxorubicin cardiomyopathy
Inna Rabinovich-Nikitin, Rimpy Dhingra, M. Guberman, Floribeth Aguilar +2 more
2017Journal of Molecular and Cellular Cardiology0 citations
Semantic Scholar
Abstract 11187: Doxorubicin Provokes Maladaptive Autophagy and Necrotic Cell Death of Cardiac Myocytes by Disrupting Mitochondrial Respiration Chain Complex IV
Rimpy Dhingra, H. Gang, V. Margulets, L. Kirshenbaum
2016Circulation0 citations
Semantic Scholar
Abstract 24: Bnip3 Provokes ROS Production and Maladaptive Autophagy by Displacing Uncoupling Protein3 (UCP3) From Cytochrome c Oxidase of Respiration Chain Complex in Cardiotoxicity
Rimpy Dhingra, V. Margulets, D. Jassal, G. Dorn +1 more
20150 citations
Semantic Scholar
Abstract 15546: Loss of Mitochondrial UCP3-Cytochrome c Oxidase Complexes Underlies Maladaptive Autophagy and Cardiac Failure in Anthracycline Cardiotoxicity
Rimpy Dhingra, V. Margulets, D. Jassal, G. Dorn +1 more
20140 citations
Semantic Scholar
Abstract 545: Generation of Oxidized Phosphatidylcholines During Hypoxia-Reoxygenation Triggers Cell Death of Postnatal Cardiac Myocytes
Devin Hasanally, V. Margulets, R. Chaudhary, L. Kirshenbaum +1 more
20140 citations
Semantic Scholar
Abstract 19146: Disruption of TRAF2-TAK1-IKKB Signaling Triggers Mitochondrial Perturbations and Necrotic Cell Death in Doxorubicin Cardiotoxicity
L. Kirshenbaum, Rimpy Dhingra, V. Margulets
2013Circulation0 citations
Semantic Scholar

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