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L. Kirshenbaum · SciRah

Researcher profile · Semantic Scholar

L. Kirshenbaum

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L. Kirshenbaum — researcher profile on SciRah

h-index: 58
Works: 243
Citations: 20K

Most-cited papers

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
D. Klionsky, Amal Kamal Abdel-Aziz, Sara Abdelfatah, M. Abdellatif +496 more
2021Autophagy4,016 citations Open access
Semantic Scholar
Editorial :Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). DOI: 10.1080/15548627.2015.1100356;WOS:000373595400001; 2-s2.0-85013763791&;PMID: 26799652
D. Klionsky, K. Abdelmohsen, A. Abe, M. Abedin +496 more
20161,544 citations Open access
Semantic Scholar
Bnip3 mediates doxorubicin-induced cardiac myocyte necrosis and mortality through changes in mitochondrial signaling
Rimpy Dhingra, V. Margulets, S. R. Roy Chowdhury, J. Thliveris +4 more
2014Proceedings of the National Academy of Sciences of the United States of America203 citations Open access
Semantic Scholar
Mitochondrial autophagy and cell survival is regulated by the circadian Clock gene in cardiac myocytes during ischemic stress
Inna Rabinovich-Nikitin, Mina Rasouli, C. J. Reitz, Illana Posen +6 more
2021Autophagy151 citations Open access
Semantic Scholar
Modulating mitofusins to control mitochondrial function and signaling
Emmanouil Zacharioudakis, B. Agianian, Vasantha Kumar M.V., N. Biris +17 more
2022Nature Communications117 citations Open access
Semantic Scholar
A small-molecule allosteric inhibitor of BAX protects against doxorubicin-induced cardiomyopathy
Dulguun Amgalan, T. Garner, Ryan Pekson, Xiaotong Jia +24 more
2020Nature Cancer115 citations Open access
Semantic Scholar
Circadian-Regulated Cell Death in Cardiovascular Diseases
Inna Rabinovich-Nikitin, B. Lieberman, T. Martino, L. Kirshenbaum
2019Circulation113 citations Open access
Semantic Scholar
Oxidized phosphatidylcholines trigger ferroptosis in cardiomyocytes during ischemia/reperfusion injury.
A. Stamenković, K. O'Hara, David Nelson, T. G. Maddaford +9 more
2021American Journal of Physiology. Heart and Circulatory Physiology103 citations
Semantic Scholar
Ellagic acid antagonizes Bnip3-mediated mitochondrial injury and necrotic cell death of cardiac myocytes.
Abhinav Dhingra, Rahul Jayas, Pegah Afshar, M. Guberman +7 more
2017Free Radical Biology & Medicine100 citations
Semantic Scholar
Reduction of myocardial ischaemia–reperfusion injury by inactivating oxidized phospholipids
C. Yeang, Devin Hasanally, Xu-Chu Que, Ming-Yow Hung +18 more
2018Cardiovascular Research87 citations Open access
Semantic Scholar
Mitochondrial dynamics: Orchestrating the journey to advanced age.
Agnieszka K. Biala, Rimpy Dhingra, L. Kirshenbaum
2015Journal of Molecular and Cellular Cardiology87 citations
Semantic Scholar
p53 Mediates Autophagy and Cell Death by a Mechanism Contingent On Bnip3
E. Wang, H. Gang, Y. Aviv, Rimpy Dhingra +2 more
2013HYPERTENSION78 citations Open access
Semantic Scholar
Mitochondrial quality control: The role of mitophagy in aging.
Ruoyang Shi, M. Guberman, L. Kirshenbaum
2017Trends in cardiovascular medicine77 citations
Semantic Scholar
Proteasomal Degradation of TRAF2 Mediates Mitochondrial Dysfunction in Doxorubicin-Cardiomyopathy.
Rimpy Dhingra, Inna Rabinovich-Nikitin, Sonny M. Rothman, M. Guberman +10 more
2022Circulation66 citations Open access
Semantic Scholar
Regulation of mitochondrial dynamics and cell fate.
Rimpy Dhingra, L. Kirshenbaum
2014Circulation Journal65 citations Open access
Semantic Scholar
Impaired NF-κB signalling underlies cyclophilin D-mediated mitochondrial permeability transition pore opening in doxorubicin cardiomyopathy.
Rimpy Dhingra, M. Guberman, Inna Rabinovich-Nikitin, Jonathon Gerstein +5 more
2019Cardiovascular Research57 citations Open access
Semantic Scholar
Bidirectional Regulation of Nuclear Factor-&kgr;B and Mammalian Target of Rapamycin Signaling Functionally Links Bnip3 Gene Repression and Cell Survival of Ventricular Myocytes
Rimpy Dhingra, H. Gang, Yan Wang, Agnieszka K. Biala +4 more
2013Circulation: Heart Failure54 citations Open access
Semantic Scholar
The interplay between cell death signaling pathways in the heart.
Agnieszka K. Biala, L. Kirshenbaum
2014Trends in cardiovascular medicine53 citations
Semantic Scholar
Inflammation in myocardial injury- mesenchymal stem cells as potential immunomodulators.
Weiang Yan, Ejlal Abu-El-Rub, S. Saravanan, L. Kirshenbaum +2 more
2019American Journal of Physiology. Heart and Circulatory Physiology51 citations Open access
Semantic Scholar
Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356
D. Klionsky, K. Abdelmohsen, A. Abe, J. Abedin +496 more
201650 citations Open access
Semantic Scholar
Ageing‐associated increase in SGLT2 disrupts mitochondrial/sarcoplasmic reticulum Ca2+ homeostasis and promotes cardiac dysfunction
Y. Olgar, E. Tuncay, Sinan Degirmenci, D. Billur +3 more
2020Journal of Cellular and Molecular Medicine45 citations Open access
Semantic Scholar
Cardiac Clocks and Preclinical Translation.
Priya Mistry, Austin T. H. Duong, L. Kirshenbaum, T. Martino
2017Heart Failure Clinics45 citations Open access
Semantic Scholar
PDK2-mediated alternative splicing switches Bnip3 from cell death to cell survival
H. Gang, Rimpy Dhingra, Jun-Jun Lin, Hai Yan +8 more
2015Journal of Cell Biology37 citations Open access
Semantic Scholar
Circadian Regulated Control of Myocardial Ischemia-Reperfusion Injury.
Inna Rabinovich-Nikitin, L. Kirshenbaum
2022Trends in cardiovascular medicine34 citations
Semantic Scholar
Circadian influence on inflammatory response during cardiovascular disease.
I. Aziz, A. McMahon, David Friedman, Inna Rabinovich-Nikitin +2 more
2020Current opinion in pharmacology (Print)33 citations Open access
Semantic Scholar
Autophagy, clock genes and cardiovascular disease.
Inna Rabinovich-Nikitin, Eryn Kirshenbaum, L. Kirshenbaum
2023Canadian Journal of Cardiology31 citations
Semantic Scholar
Activation of Mitophagy in High-Fat Diet-Induced Diabetic Cardiomyopathy.
Inna Rabinovich-Nikitin, Rimpy Dhingra, L. Kirshenbaum
2019Circulation Research31 citations Open access
Semantic Scholar
Fibroblast growth factor-2-mediated protection of cardiomyocytes from the toxic effects of doxorubicin requires the mTOR/Nrf-2/HO-1 pathway
Navid Koleini, B. Nickel, Jie Wang, Zeinab Roveimiab +4 more
2017OncoTarget26 citations Open access
Semantic Scholar
NF-κB p65 Attenuates Cardiomyocyte PGC-1α Expression in Hypoxia
Inna Rabinovich-Nikitin, A. Blant, Rimpy Dhingra, L. Kirshenbaum +1 more
2022Cells24 citations Open access
Semantic Scholar
Sensory neurons derived from diabetic rats exhibit deficits in functional glycolysis and ATP that are ameliorated by IGF-1
M. Aghanoori, V. Margulets, Darrell R. Smith, L. Kirshenbaum +2 more
2021Molecular Metabolism24 citations Open access
Semantic Scholar
Ulk1/Rab9-mediated alternative mitophagy confers cardioprotection during energy stress
Rimpy Dhingra, Inna Rabinovich-Nikitin, L. Kirshenbaum
2019Journal of Clinical Investigation24 citations Open access
Semantic Scholar
Reductions in the Cardiac Transient Outward K+ Current Ito Caused by Chronic β-Adrenergic Receptor Stimulation Are Partly Rescued by Inhibition of Nuclear Factor κB*
Brian K. Panama, A. Korogyi, Roozbeh Aschar-Sobbi, Yena Oh +5 more
2016Journal of Biological Chemistry22 citations Open access
Semantic Scholar
YAP/TFEB pathway promotes autophagic cell death and hypertrophic cardiomyopathy in lysosomal storage diseases.
Inna Rabinovich-Nikitin, L. Kirshenbaum
2021Journal of Clinical Investigation21 citations Open access
Semantic Scholar
The Role of Advanced Glycation End-Products in the Pathophysiology and Pharmacotherapy of Cardiovascular Disease
K. Mota, C. D. de Vasconcelos, L. Kirshenbaum, N. Dhalla
2025International Journal of Molecular Sciences19 citations
Semantic Scholar
Hypoxia‐induced downregulation of cyclooxygenase 2 leads to the loss of immunoprivilege of allogeneic mesenchymal stem cells
Niketa Sareen, Ejlal Abu-El-Rub, H. Ammar, Weiang Yan +8 more
2020The FASEB Journal17 citations
Semantic Scholar
Bcl-2/adenovirus E1B 19-kDa interacting protein (BNip3) has a key role in the mitochondrial dysfunction induced by mutant huntingtin.
F. Sassone, V. Margulets, Annamaria Maraschi, S. Rodighiero +5 more
2015Human Molecular Genetics17 citations
Semantic Scholar
Epigenetic regulation of canonical TNFα pathway by HDAC1 determines survival of cardiac myocytes.
H. Gang, James Shaw, Rimpy Dhingra, J. Davie +1 more
2013American Journal of Physiology. Heart and Circulatory Physiology16 citations
Semantic Scholar
DIAPH1-MFN2 interaction decreases the endoplasmic reticulum-mitochondrial distance and promotes cardiac injury following myocardial ischemia
L. Kirshenbaum, Rimpy Dhingra, R. Bravo-Sagua, S. Lavandero
2024Nature Communications14 citations Open access
Semantic Scholar
Ellagic acid inhibits mitochondrial fission protein Drp-1 and cell proliferation in cancer
S. Yakobov, Rimpy Dhingra, V. Margulets, Abhinav Dhingra +2 more
2023Molecular and Cellular Biochemistry13 citations
Semantic Scholar
Intersection of autophagy regulation and circadian rhythms in the heart.
Inna Rabinovich-Nikitin, M. Love, L. Kirshenbaum
2022Biochimica et Biophysica Acta - Molecular Basis of Disease13 citations Open access
Semantic Scholar
Elimination or neutralization of endogenous high-molecular-weight FGF2 mitigates doxorubicin-induced cardiotoxicity.
Navid Koleini, Jon-Jon Santiago, B. Nickel, G. Sequiera +7 more
2019American Journal of Physiology. Heart and Circulatory Physiology13 citations
Semantic Scholar
Mst-1 switches between cardiac cell life and death
Rimpy Dhingra, L. Kirshenbaum
2013Nature Medicine11 citations
Semantic Scholar
Statins Impair Survival of Primary Human Mesenchymal Progenitor Cells via Mevalonate Depletion, NF-κB Signaling, and Bnip3
Yun Li, Alison L. Müller, M. Ngo, K. Sran +4 more
2015Journal of Cardiovascular Translational Research10 citations
Semantic Scholar
IKKβ stabilizes Mitofusin 2 and suppresses doxorubicin cardiomyopathy.
M. Guberman, Rimpy Dhingra, J. Cross, V. Margulets +3 more
2024Cardiovascular Research9 citations
Semantic Scholar
Attenuation of Obesity Cardiomyopathy by Ulk1/Rab9 Mediated Alternative Mitophagy.
Inna Rabinovich-Nikitin, Rachel C Cogan, L. Kirshenbaum
2021Circulation Research9 citations Open access
Semantic Scholar
Exercise-Induced Myonectin Protects Against Ischemia-Reperfusion Injury.
Inna Rabinovich-Nikitin, L. Kirshenbaum
2018Circulation Research8 citations Open access
Semantic Scholar
Inhibition of MMP prevents doxorubicin-induced cardiotoxicity by attenuating cardiac intracellular and extracellular matrix remodelling.
Inna Rabinovich-Nikitin, M. Love, L. Kirshenbaum
2020Cardiovascular Research7 citations Open access
Semantic Scholar
Ferroptosis: beating on death's door.
Rimpy Dhingra, A. Ravandi, L. Kirshenbaum
2018American Journal of Physiology. Heart and Circulatory Physiology7 citations
Semantic Scholar
Cyclophilin D phosphorylation is critical for mitochondrial calcium uniporter regulated permeability transition pore sensitivity.
Rimpy Dhingra, B. Lieberman, L. Kirshenbaum
2018Cardiovascular Research7 citations Open access
Semantic Scholar
Molecular Mechanisms Underlying Anthracycline Cardiotoxicity: Challenges in Cardio-Oncology
Rimpy Dhingra, V. Margulets, L. Kirshenbaum
20176 citations Open access
Semantic Scholar

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