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Guo-Qiang Gu · SciRah

Researcher profile · Semantic Scholar

Guo-Qiang Gu

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Guo-Qiang Gu — researcher profile on SciRah

h-index: 34
Works: 81
Citations: 7,103

Most-cited papers

Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors.
Guo-Qiang Gu, Jolanta Dubauskaite, D. Melton
2002Development1,624 citations
Semantic Scholar
The vascular basement membrane: a niche for insulin gene expression and Beta cell proliferation.
G. Nikolova, N. Jabs, I. Konstantinova, Anna Domogatskaya +8 more
2006Developmental Cell522 citations Open access
Semantic Scholar
Adult Hepatocytes Are Generated by Self-Duplication Rather than Stem Cell Differentiation
Kilangsungla Yanger, D. Knigin, Yiwei Zong, Lara R. Maggs +4 more
2014Cell Stem Cell413 citations Open access
Semantic Scholar
Role of VEGF-A in vascularization of pancreatic islets.
E. Lammert, Guo-Qiang Gu, M. Mclaughlin, Dennis Brown +5 more
2003Current Biology399 citations Open access
Semantic Scholar
Diabetes Recovery By Age-Dependent Conversion of Pancreatic δ-Cells Into Insulin Producers
S. Chera, D. Baronnier, L. Ghila, V. Cigliola +7 more
2014Nature386 citations Open access
Semantic Scholar
Temporal control of neurogenin3 activity in pancreas progenitors reveals competence windows for the generation of different endocrine cell types.
K. Johansson, Umut Dursun, Nathalie Jordan, Guo-Qiang Gu +3 more
2007Developmental Cell368 citations Open access
Semantic Scholar
Global expression analysis of gene regulatory pathways during endocrine pancreatic development
Guo-Qiang Gu, James M. Wells, D. Dombkowski, F. Preffer +2 more
2004Development245 citations Open access
Semantic Scholar
Direct lineage tracing reveals the ontogeny of pancreatic cell fates during mouse embryogenesis.
Guo-Qiang Gu, Juliana R. Brown, D. Melton
2003Mechanisms of Development235 citations Open access
Semantic Scholar
Genetic labeling does not detect epithelial-to-mesenchymal transition (EMT) of cholangiocytes in liver fibrosis in mice
D. Scholten, Christoph H. Österreicher, A. Scholten, K. Iwaisako +3 more
2010Gastroenterology234 citations Open access
Semantic Scholar
A CK19CreERT knockin mouse line allows for conditional DNA recombination in epithelial cells in multiple endodermal organs
A. Means, Yanwen Xu, Aizhen Zhao, Kevin C. Ray +1 more
2008Genesis195 citations Open access
Semantic Scholar
Sustained Neurog3 expression in hormone-expressing islet cells is required for endocrine maturation and function
Sui Wang, J. Jensen, Philip A. Seymour, Wei Hsu +5 more
2009Proceedings of the National Academy of Sciences of the United States of America180 citations Open access
Semantic Scholar
Transient cytokine treatment induces acinar cell reprogramming and regenerates functional beta cell mass in diabetic mice
L. Baeyens, M. Lemper, G. Leuckx, S. De Groef +17 more
2013Nature Biotechnology179 citations Open access
Semantic Scholar
Neurog3 gene dosage regulates allocation of endocrine and exocrine cell fates in the developing mouse pancreas
Sui Wang, Jingbo Yan, D. A. Anderson, Yanwen Xu +4 more
2009Developmental Biology153 citations Open access
Semantic Scholar
Epithelial Tissues Have Varying Degrees of Susceptibility to KrasG12D-Initiated Tumorigenesis in a Mouse Model
Kevin C. Ray, Kayla M. Bell, Jingbo Yan, Guo-Qiang Gu +3 more
2011PLoS ONE123 citations Open access
Semantic Scholar
Loss of Fbw7 Reprograms Adult Pancreatic Ductal Cells into α, δ, and β Cells
Rocío Sancho, R. Gruber, Guo-Qiang Gu, A. Behrens
2014Cell Stem Cell121 citations Open access
Semantic Scholar
Obesity Suppresses Cell-Competition-Mediated Apical Elimination of RasV12-Transformed Cells from Epithelial Tissues
Ayana Sasaki, T. Nagatake, Riku Egami, Guo-Qiang Gu +5 more
2018Cell Reports115 citations Open access
Semantic Scholar
Non-parallel recombination limits Cre-LoxP-based reporters as precise indicators of conditional genetic manipulation
Jing Liu, Spencer G. Willet, E. Bankaitis, Yanwen Xu +2 more
2013Genesis112 citations Open access
Semantic Scholar
Microtubules negatively regulate insulin secretion in pancreatic β cells
Xiao-Dong Zhu, Ruiying Hu, M. Brissova, R. Stein +3 more
2015Developmental Cell105 citations Open access
Semantic Scholar
Synaptotagmin 4 regulates pancreatic β-cell maturation by modulating the Ca2+ sensitivity of insulin secretion vesicles
Chen Huang, E. Walker, P. Dadi, Ruiying Hu +16 more
2018Developmental Cell93 citations Open access
Semantic Scholar
Pancreatic α- and β-cellular clocks have distinct molecular properties and impact on islet hormone secretion and gene expression
V. Petrenko, C. Saini, L. Giovannoni, C. Gobet +8 more
2017Genes & Development89 citations Open access
Semantic Scholar
Myt1 and Ngn3 form a feed-forward expression loop to promote endocrine islet cell differentiation.
Sui Wang, J. Hecksher-Sørensen, Yanwen Xu, Aizhen Zhao +4 more
2008Developmental Biology88 citations Open access
Semantic Scholar
Ngn3+ endocrine progenitor cells control the fate and morphogenesis of pancreatic ductal epithelium
J. Magenheim, Allon M. Klein, B. Stanger, R. Ashery-Padan +3 more
2011Developmental Biology84 citations Open access
Semantic Scholar
Loss of Myt1 function partially compromises endocrine islet cell differentiation and pancreatic physiological function in the mouse.
Sui Wang, Jia Zhang, Aizhen Zhao, S. Hipkens +2 more
2007Mechanisms of Development69 citations Open access
Semantic Scholar
Reconstituting pancreas development from purified progenitor cells reveals genes essential for islet differentiation
T. Sugiyama, C. M. Benitez, Amar Ghodasara, Lucy Liu +7 more
2013Proceedings of the National Academy of Sciences of the United States of America67 citations Open access
Semantic Scholar
Cooperation between HMGA1, PDX-1, and MafA is Essential for Glucose-Induced Insulin Transcription in Pancreatic Beta Cells
B. Arcidiacono, Stefania Iiritano, E. Chiefari, F. Brunetti +3 more
2014Frontiers in Endocrinology58 citations Open access
Semantic Scholar
The MAFB transcription factor impacts islet α-cell function in rodents and represents a unique signature of primate islet β-cells.
Elizabeth Conrad, C. Dai, Jason M. Spaeth, Min Guo +11 more
2016American Journal of Physiology. Endocrinology and Metabolism50 citations Open access
Semantic Scholar
Generation of islet-like cells from mouse gall bladder by direct ex vivo reprogramming
R. Hickey, Feorillo Galivo, J. Schug, M. Brehm +10 more
2013Stem Cell Research50 citations Open access
Semantic Scholar
MafA is a dedicated activator of the insulin gene in vivo.
I. Artner, Y. Hang, Min Guo, Guo-Qiang Gu +1 more
2008Journal of Endocrinology47 citations Open access
Semantic Scholar
Glucose Regulates Microtubule Disassembly and the Dose of Insulin Secretion via Tau Phosphorylation
Ada Admin, Kung-Hsien Ho, Xiaodun Yang, Anna B. Osipovich +5 more
2020Diabetes44 citations Open access
Semantic Scholar
Endothelial Cells Control Pancreatic Cell Fate at Defined Stages through EGFL7 Signaling
Der-I Kao, Lauretta A. Lacko, B. Ding, Chen Huang +5 more
2015Stem Cell Reports43 citations Open access
Semantic Scholar
Neurog3-independent methylation is the earliest detectable mark distinguishing pancreatic progenitor identity
Jing Liu, A. Banerjee, Charles A. Herring, Jonathan Attalla +11 more
2019Developmental Cell42 citations Open access
Semantic Scholar
Quantitative assessment of cell population diversity in single-cell landscapes
Qi Liu, Charles A. Herring, Quan-Hu Sheng, Jie Ping +8 more
2018bioRxiv42 citations Open access
Semantic Scholar
Gαo Represses Insulin Secretion by Reducing Vesicular Docking in Pancreatic β-Cells
Aizhen Zhao, M. Ohara-Imaizumi, Marcella Brissova, R. Benninger +10 more
2010Diabetes36 citations Open access
Semantic Scholar
Modulation of Golgi-associated microtubule nucleation throughout the cell cycle
A. Maia, Xiao-Dong Zhu, P. Miller, Guo-Qiang Gu +2 more
2012Cytoskeleton34 citations Open access
Semantic Scholar
Pancreatic Inflammation Redirects Acinar to Beta Cell Reprogramming
Hannah W Clayton, Anna B. Osipovich, Jennifer S. Stancill, J. Schneider +7 more
2016Cell Reports32 citations Open access
Semantic Scholar
Regulation of glucose-dependent Golgi-derived microtubules by cAMP/EPAC2 promotes secretory vesicle biogenesis in pancreatic β-cells
Kathryn P. Trogden, Xiao-Dong Zhu, Justin Lee, C. Wright +2 more
2019Current Biology30 citations Open access
Semantic Scholar
Cre reconstitution allows for DNA recombination selectively in dual-marker-expressing cells in transgenic mice
Yanwen Xu, Gang Xu, Bin-Dong Liu, Guo-Qiang Gu
2007Nucleic Acids Research30 citations Open access
Semantic Scholar
GRP94 Is an Essential Regulator of Pancreatic &bgr;-Cell Development, Mass, and Function in Male Mice
Do-sung Kim, Lili Song, Jing-Jing Wang, Hongju Wu +4 more
2018Endocrinology26 citations Open access
Semantic Scholar
Mitofusins Mfn1 and Mfn2 Are Required to Preserve Glucose- but Not Incretin-Stimulated β-Cell Connectivity and Insulin Secretion
E. Georgiadou, Charanya Muralidharan, Michelle M. Martinez, Pauline Chabosseau +20 more
2020bioRxiv25 citations Open access
Semantic Scholar
Generation of a Tenascin-C-CreER2 Knockin Mouse Line for Conditional DNA Recombination in Renal Medullary Interstitial Cells
Wenjuan He, Qiong-Hong Xie, Ying-Ying Wang, Jing Chen +5 more
2013PLoS ONE25 citations Open access
Semantic Scholar
ROCK-nmMyoII, Notch and Neurog3 gene-dosage link epithelial morphogenesis with cell fate in the pancreatic endocrine-progenitor niche
E. Bankaitis, M. Bechard, Guo-Qiang Gu, M. Magnuson +1 more
2018Development24 citations Open access
Semantic Scholar
The fringe molecules induce endocrine differentiation in embryonic endoderm by activating cMyt1/cMyt3.
Yanwen Xu, Sui Wang, Jia Zhang, Aizhen Zhao +2 more
2006Developmental Biology24 citations Open access
Semantic Scholar
Matters arising: Insufficient evidence that pancreatic β cells are derived from adult ductal Neurog3-expressing progenitors
J. Magenheim, M. Maestro, N. Sharon, P. Herrera +7 more
2023Cell Stem Cell22 citations Open access
Semantic Scholar
Microtubules regulate pancreatic β-cell heterogeneity via spatiotemporal control of insulin secretion hot spots
Kathryn P. Trogden, Justin Lee, Kai M. Bracey, Kung-Hsien Ho +10 more
2021eLife20 citations Open access
Semantic Scholar
Myt Transcription Factors prevent stress-response gene overactivation to enable postnatal pancreatic β-cell proliferation, function, and survival
Ruiying Hu, E. Walker, Chen Huang, Yanwen Xu +11 more
2020Developmental Cell20 citations Open access
Semantic Scholar
Nkx2.2 is expressed in a subset of enteroendocrine cells with expanded lineage potential.
S. Gross, D. Balderes, Jing Liu, S. Asfaha +3 more
2015American Journal of Physiology - Gastrointestinal and Liver Physiology20 citations Open access
Semantic Scholar
A developmental lineage-based gene co-expression network for mouse pancreatic β-cells reveals a role for Zfp800 in pancreas development
Anna B. Osipovich, Karrie D. Dudek, Emily Greenfest-Allen, Jean-Philippe Cartailler +8 more
2021Development18 citations Open access
Semantic Scholar
Coregulator Sin3a Promotes Postnatal Murine β-Cell Fitness by Regulating Genes in Ca2+ Homeostasis, Cell Survival, Vesicle Biosynthesis, Glucose Metabolism, and Stress Response
Ada Admin, Xiaodun Yang, Sarah M. Graff, Cody N. Heiser +10 more
2020Diabetes18 citations Open access
Semantic Scholar
Effective isolation of functional islets from neonatal mouse pancreas
Chen Huang, Guo-Qiang Gu
2017Journal of Visualized Experiments17 citations Open access
Semantic Scholar
St18 specifies globus pallidus projection neuron identity in MGE lineage
Luke Nunnelly, M. Campbell, Dylan I. Lee, Patrick D. Dummer +3 more
2021bioRxiv15 citations Open access
Semantic Scholar

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