Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

Neha Bhagwat · SciRah

Researcher profile · Semantic Scholar

Neha Bhagwat

Share profile

Neha Bhagwat — researcher profile on SciRah

h-index: 20
Works: 59
Citations: 5,247

Most-cited papers

Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation
M. Figueroa, Omar Abdel-Wahab, Chao Lu, P. Ward +22 more
2010Cancer Cell2,733 citations Open access
Semantic Scholar
Heterodimeric JAK-STAT Activation as a Mechanism of Persistence to JAK2 Inhibitor Therapy
Priya Koppikar, Neha Bhagwat, O. Kilpivaara, T. Manshouri +18 more
2011Nature366 citations Open access
Semantic Scholar
JAK-STAT Pathway Activation in Malignant and Non-Malignant Cells Contributes to MPN Pathogenesis and Therapeutic Response
M. Kleppe, Minsuk Kwak, Priya Koppikar, M. Riester +19 more
2015Cancer Discovery276 citations Open access
Semantic Scholar
Cholesterol efflux in megakaryocyte progenitors suppresses platelet production and thrombocytosis
A. Murphy, N. Bijl, L. Yvan-Charvet, C. Welch +8 more
2013Nature Medicine210 citations Open access
Semantic Scholar
Combining Machine Learning and Nanofluidic Technology To Diagnose Pancreatic Cancer Using Exosomes.
J. Ko, Neha Bhagwat, S. Yee, N. Ortiz +10 more
2017ACS Nano208 citations
Semantic Scholar
HSP90 is a therapeutic target in JAK2-dependent myeloproliferative neoplasms in mice and humans.
Sachie Marubayashi, Priya Koppikar, Tony Taldone, O. Abdel-Wahab +14 more
2010Journal of Clinical Investigation191 citations Open access
Semantic Scholar
Highly specific enrichment of rare nucleic acid fractions using Thermus thermophilus argonaute with applications in cancer diagnostics
Jin-Zhao Song, Jorrit W. Hegge, M. Mauk, Junman Chen +9 more
2019Nucleic Acids Research138 citations Open access
Semantic Scholar
Modulation of activation-loop phosphorylation by JAK inhibitors is binding mode dependent
R. Andraos, Zhiyan Qian, D. Bonenfant, Joëlle Rubert +20 more
2012Cancer Discovery125 citations Open access
Semantic Scholar
Metastatic progression is associated with dynamic changes in the local microenvironment
Nicole M. Aiello, D. L. Bajor, Robert J. Norgard, Amine Sahmoud +6 more
2016Nature Communications120 citations Open access
Semantic Scholar
Identification of a Novel Lysophospholipid Acyltransferase in Saccharomyces cerevisiae*
Shilpa Jain, N. Stanford, Neha Bhagwat, Brian Seiler +3 more
2007Journal of Biological Chemistry111 citations Open access
Semantic Scholar
Improved targeting of JAK2 leads to increased therapeutic efficacy in myeloproliferative neoplasms.
Neha Bhagwat, Priya Koppikar, Matthew D. Keller, Sachie Marubayashi +10 more
2014Blood109 citations Open access
Semantic Scholar
A multi-analyte panel consisting of extracellular vesicle miRNAs and mRNAs, cfDNA, and CA19-9 shows utility for diagnosis and staging of pancreatic adenocarcinoma
Zijian Yang, M. LaRiviere, J. Ko, Jacob E. Till +15 more
2020Clinical Cancer Research85 citations Open access
Semantic Scholar
PRMT5 inhibition modulates E2F1 methylation and gene regulatory networks leading to therapeutic efficacy in JAK2V617F mutant MPN
F. Pastore, Neha Bhagwat, A. Pastore, Aliaksandra Radzisheuskaya +22 more
2020Cancer Discovery68 citations Open access
Semantic Scholar
An integrated flow cytometry-based platform for isolation and molecular characterization of circulating tumor single cells and clusters
Neha Bhagwat, Keely A. Dulmage, C. Pletcher, Ling Wang +11 more
2018Scientific Reports65 citations Open access
Semantic Scholar
miRNA Profiling of Magnetic Nanopore-Isolated Extracellular Vesicles for the Diagnosis of Pancreatic Cancer.
J. Ko, Neha Bhagwat, Taylor A. Black, S. Yee +6 more
2018Cancer Research62 citations Open access
Semantic Scholar
Genetic studies reveal an unexpected negative regulatory role for Jak2 in thrombopoiesis.
S. Meyer, Matthew D. Keller, Brittany Woods, Lindsay M. LaFave +5 more
2014Blood57 citations Open access
Semantic Scholar
HDL and Glut1 inhibition reverse a hypermetabolic state in mouse models of myeloproliferative disorders
E. Gautier, M. Westerterp, Neha Bhagwat, S. Cremers +7 more
2013Journal of Experimental Medicine49 citations Open access
Semantic Scholar
Sensitivity and resistance of JAK2 inhibitors to myeloproliferative neoplasms
Neha Bhagwat, R. Levine, Priya Koppikar
2013International journal of hematology36 citations Open access
Semantic Scholar
A magnetic micropore chip for rapid (< 1 hour) unbiased circulating tumor cell isolation and in-situ RNA analysis
J. Ko, Neha Bhagwat, S. Yee, Taylor A. Black +7 more
2017Lab on a Chip35 citations Open access
Semantic Scholar
Tumor-specific HSP90 inhibition as a therapeutic approach in JAK-mutant acute lymphoblastic leukemias.
N. Kucine, Sachie Marubayashi, Neha Bhagwat, E. Papalexi +21 more
2015Blood34 citations Open access
Semantic Scholar
Circulating KRAS G12D but not G12V is associated with survival in metastatic pancreatic ductal adenocarcinoma
Jacob E. Till, Lee McDaniel, Changgee Chang, Qi Long +38 more
2024Nature Communications18 citations Open access
Semantic Scholar
PRMT5 inhibition drives therapeutic vulnerability to combination treatment with BCL-2 inhibition in mantle cell lymphoma
Fiona Brown-Burke, I. Hwang, S. Sloan, C. Hinterschied +20 more
2023Blood Advances16 citations Open access
Semantic Scholar
Abstract 983: Preclinical characterization of PRT1419, a potent, selective and orally available inhibitor of MCL1
Neha Bhagwat, Alexander Grego, W. Gowen-MacDonald, Min Wang +7 more
2021Experimental and Molecular Therapeutics16 citations
Semantic Scholar
Acceleration of Bcr-Abl+ leukemia induced by deletion of JAK2
Eva Grundschober, Andrea Hoelbl-Kovacic, Neha Bhagwat, B. Kovacic +8 more
2014Leukemia16 citations Open access
Semantic Scholar
A Phase 1 Dose Escalation Study of Protein Arginine Methyltransferase 5 (PRMT5) Inhibitor PRT543 in Patients with Myeloid Malignancies
M. Patel, V. Monga, S. Jauhari, D. Stevens +15 more
2021Blood15 citations Open access
Semantic Scholar
An Integrated Enrichment System to Facilitate Isolation and Molecular Characterization of Single Cancer Cells from Whole Blood
Li-Ping Yu, S. Sa, Ling Wang, Keely A. Dulmage +8 more
2018Cytometry Part A15 citations Open access
Semantic Scholar
Abstract P039: A phase 1 dose escalation study of protein arginine methyltransferase 5 (PRMT5) inhibitor PRT543 in patients with advanced solid tumors and lymphoma
M. McKean, M. Patel, R. Wesolowski, R. Ferrarotto +13 more
2021Poster Presentations - Proffered Abstracts12 citations
Semantic Scholar
HSP 90 is a therapeutic target in JAK 2-dependent myeloproliferative neoplasms in mice and humans
Sachie Marubayashi, Priya Koppikar, Tony Taldone, O. Abdel-Wahab +14 more
201811 citations
Semantic Scholar
Abstract 3263: Preclinical characterization of PRT3789, a potent and selective SMARCA2 targeted degrader
Michael Hulse, A. Agarwal, Min Wang, Jack Carter +17 more
2022Cancer Research8 citations
Semantic Scholar
Non-canonical Hedgehog signaling mediates profibrotic hematopoiesis-stroma crosstalk in myeloproliferative neoplasms
Jessica E. Pritchard, Juliette E. Pearce, I. Snoeren, Stijn N. R. Fuchs +27 more
2023Cell Reports6 citations Open access
Semantic Scholar
Abstract 1137: PRMT5 inhibition regulates alternative splicing and DNA damage repair pathways in SF3B1 R625G expressing uveal melanoma cells
Koichi Ito, V. Thodima, Jack Carter, Neha Bhagwat +9 more
2021Experimental and Molecular Therapeutics6 citations
Semantic Scholar
Combination Therapy Using JAK2 and HSP90 Inhibitors Increased Efficacy in Myelofibrosis in Vivo
R. Levine, Priya Koppikar, Sachie Marubayashi, Neha Bhagwat +3 more
20125 citations
Semantic Scholar
PRT2527, a Novel Highly Selective Cyclin-Dependent Kinase 9 (CDK9) Inhibitor, Has Potent Anti-Leukemic Activity in Preclinical Primary Models of Human B-ALL, T-ALL, and CLL
Neha Bhagwat, B. Ruggeri, Yang W. Zhang, Yaron Mosesson +3 more
2022Blood4 citations Open access
Semantic Scholar
Abstract P044: A phase 1 dose escalation study of protein arginine methyltransferase 5 (PRMT5) brain penetrant inhibitor PRT811 in patients with advanced solid tumors, including recurrent high-grade gliomas
G. Falchook, J. Glass, V. Monga, P. Giglio +10 more
2021Poster Presentations - Proffered Abstracts4 citations
Semantic Scholar
Flow Cytometric Methods for Circulating Tumor Cell Isolation and Molecular Analysis.
Neha Bhagwat, E. Carpenter
2017Advances in Experimental Medicine and Biology4 citations
Semantic Scholar
Abstract 420: Combination of the MCL1 inhibitor PRT1419 and SMARCA2 degrader PRT3789 shows combinatorial benefit in SMARCA4 deleted lung cancer
Norman Fultang, Neha Bhagwat, D. Heiser, Alexander Grego +6 more
2022Cancer Research3 citations
Semantic Scholar
Abstract 1138: PRMT5 inhibition downregulates MYB and NOTCH1 signaling, key molecular drivers of adenoid cystic carcinoma
Jack Carter, Koichi Ito, V. Thodima, Neha Bhagwat +6 more
2021Experimental and Molecular Therapeutics3 citations
Semantic Scholar
Mathematical modeling reveals alternative JAK inhibitor treatment in myeloproliferative neoplasms
K. Shank, A. Dunbar, Priya Koppikar, M. Kleppe +8 more
2019Haematologica3 citations Open access
Semantic Scholar
Abstract 2159: PRMT5 inhibitor PRT543 displays potent antitumor activity in U2AF1S34F and RBM10LOF spliceosome-mutant non-small cell lung cancer in vitro and in vivo
Jack Carter, Koichi Ito, V. Thodima, M. Sivakumar +7 more
2022Cancer Research2 citations
Semantic Scholar
Abstract 2915: Preclinical characterization of PRT543, a potent and selective inhibitor of protein arginine methyltransferase 5 (PRMT5), with broad antitumor activity inin vitroandin vivomodels
Neha Bhagwat, Yang W. Zhang, Hong Lin, Min Wang +16 more
2020Experimental and Molecular Therapeutics2 citations
Semantic Scholar
Highly Specific Enrichment of Rare Nucleic Acids using Thermus Thermophilus Argonaute
Jin-Zhao Song, Jorrit W. Hegge, M. Mauk, Neha Bhagwat +9 more
2018bioRxiv2 citations Open access
Semantic Scholar
Metabolic Syndromes and Malignant Transformation: Where the Twain Shall Meet
Neha Bhagwat, R. Levine
2010Science Translational Medicine2 citations
Semantic Scholar
PRMT5 Inhibition Potentiates Anti-Tumor Immune Targeting of EBV-Driven B Cell Lymphoproliferative Disease
E. Ahmed, C. Weigel, Rachel Saadey, Eric Brooks +19 more
2022Blood1 citations Open access
Semantic Scholar
Predicting Targets for Genome Editing with Long Short Term Memory Networks
Neha Bhagwat, Natalia Khuri
2021Advances in Computer Vision and Computational Biology1 citations
Semantic Scholar
Mathematical Optimization of JAK Inhibitor Dose and Scheduling for MPN Patients
K. Shank, Priya Koppikar, Neha Bhagwat, Matthew D. Keller +3 more
20141 citations
Semantic Scholar
Improved targeting of JAK 2 leads to increased therapeutic ef fi cacy in myeloproliferative neoplasms
Neha Bhagwat, Priya Koppikar, Matthew D. Keller, Sachie Marubayashi +10 more
20141 citations
Semantic Scholar
Abstract 6147: MCL1 inhibitor PRT1419 demonstrates anti-tumor activity in PBRM1-altered clear cell renal cancer and synergizes with standard of care agents
Norman Fultang, Brian Vidal, Ashley M. Schwab, Alexander Grego +4 more
2023Cancer Research0 citations
Semantic Scholar
Abstract 6277: Selective and orally bioavailable SMARCA2 targeted degraders induce synthetic lethality in SMARCA4- deficient solid tumor
Koichi Ito, Artem Shvartsbart, J. Rager, A. Agarwal +28 more
2023Cancer Research0 citations
Semantic Scholar
Abstract 2792: Development of pharmacodynamic assays for quantifying SMARCA2 protein degradation and target gene expression in response to a SMARCA2 degrader (PRT3789)
Andrew Moore, Carly Bachner, Lalitha Srinivasan, P. Kurup +5 more
2023Cancer Research0 citations
Semantic Scholar
Abstract 1594: SMARCA2 (BRM) degraders promotes differentiation and inhibit proliferation in AML models
A. Agarwal, O. Osinubi, K. Vykuntam, Norman Fultang +5 more
2023Cancer Research0 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

R. Levine×19
Invite
R. Levine — researcher profile on SciRah
P. Scherle×18
Invite
P. Scherle — researcher profile on SciRah
K. Vaddi×13
Invite
K. Vaddi — researcher profile on SciRah
Priya Koppikar×12
Invite
Priya Koppikar — researcher profile on SciRah

Sachie Marubayashi

×9

Invite

Sachie Marubayashi — researcher profile on SciRah

Alexander Grego×9

Invite

Alexander Grego — researcher profile on SciRah

E. Carpenter×8

Invite

E. Carpenter — researcher profile on SciRah

Invite

B. Ruggeri — researcher profile on SciRah

Invite

G. Chiosis — researcher profile on SciRah

Matthew D. Keller×7

Invite

Matthew D. Keller — researcher profile on SciRah

Invite

S. Yee — researcher profile on SciRah

O. Abdel-Wahab×6

Invite

O. Abdel-Wahab — researcher profile on SciRah