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E. Papalexi · SciRah

Researcher profile · Semantic Scholar

E. Papalexi

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E. Papalexi — researcher profile on SciRah

h-index: 22
Works: 60
Citations: 43K

Most-cited papers

Comprehensive integration of single-cell data
T. Stuart, Andrew W. Butler, Paul J. Hoffman, C. Hafemeister +6 more
2018bioRxiv14K citations Open access
Semantic Scholar
Integrated analysis of multimodal single-cell data
Yu-Han Hao, S. Hao, E. Andersen-Nissen, W. Mauck +21 more
2020bioRxiv13K citations Open access
Semantic Scholar
Integrating single-cell transcriptomic data across different conditions, technologies, and species
Andrew W. Butler, Paul J. Hoffman, P. Smibert, E. Papalexi +1 more
2018Nature Biotechnology11K citations Open access
Semantic Scholar
Single-cell RNA sequencing to explore immune cell heterogeneity
E. Papalexi, R. Satija
2017Nature reviews. Immunology1,635 citations
Semantic Scholar
Scalable, multimodal profiling of chromatin accessibility, gene expression, and protein levels in single cells
Eleni P. Mimitou, C. Lareau, Kelvin Y. Chen, A. Zorzetto-Fernandes +17 more
2021Nature Biotechnology482 citations Open access
Semantic Scholar
Expanding the CITE-seq tool-kit: Detection of proteins, transcriptomes, clonotypes and CRISPR perturbations with multiplexing, in a single assay
Eleni P. Mimitou, A. Cheng, A. Montalbano, S. Hao +10 more
2019Nature Methods453 citations Open access
Semantic Scholar
Loss of BAP1 function leads to EZH2-dependent transformation
Lindsay M. LaFave, W. Béguelin, R. Koche, Matt Teater +27 more
2015Nature Medicine336 citations Open access
Semantic Scholar
JAK-STAT Pathway Activation in Malignant and Non-Malignant Cells Contributes to MPN Pathogenesis and Therapeutic Response
M. Kleppe, Minsuk Kwak, Priya Koppikar, M. Riester +19 more
2015Cancer Discovery276 citations Open access
Semantic Scholar
Characterizing the molecular regulation of inhibitory immune checkpoints with multi-modal single-cell screens.
E. Papalexi, Eleni P. Mimitou, Andrew W. Butler, Samantha Foster +7 more
2021Nature Genetics214 citations Open access
Semantic Scholar
Dual Targeting of Oncogenic Activation and Inflammatory Signaling Increases Therapeutic Efficacy in Myeloproliferative Neoplasms
M. Kleppe, R. Koche, L. Zou, P. van Galen +20 more
2017Cancer Cell170 citations Open access
Semantic Scholar
Tahoe-100M: A Giga-Scale Single-Cell Perturbation Atlas for Context-Dependent Gene Function and Cellular Modeling
Jesse Zhang, Airol A. Ubas, R. de Borja, Valentine Svensson +28 more
2025bioRxiv158 citations
Semantic Scholar
Dose-dependent role of the cohesin complex in normal and malignant hematopoiesis
A. Viny, C. Ott, B. Spitzer, M. Rivas +13 more
2015Journal of Experimental Medicine149 citations Open access
Semantic Scholar
Molecular transitions in early progenitors during human cord blood hematopoiesis
Shi-Wei Zheng, E. Papalexi, Andrew W. Butler, William Stephenson +1 more
2018Molecular Systems Biology139 citations Open access
Semantic Scholar
Dual Targeting of Oncogenic Activation and Inflammatory Signaling Increases Therapeutic Efficacy in Myeloproliferative Neoplasms
M. Kleppe, Richard P. Koche, L. Zou, P. van Galen +20 more
2018Cancer Cell136 citations Open access
Semantic Scholar
Efficient combinatorial targeting of RNA transcripts in single cells with Cas13 RNA Perturb-seq
H. Wessels, A. Méndez-Mancilla, Yu-Han Hao, E. Papalexi +7 more
2022bioRxiv79 citations Open access
Semantic Scholar
Jak1 Integrates Cytokine Sensing to Regulate Hematopoietic Stem Cell Function and Stress Hematopoiesis
M. Kleppe, M. Spitzer, Sheng Li, Corinne E. Hill +12 more
2017Cell Stem Cell75 citations Open access
Semantic Scholar
Kinetics of adult hematopoietic stem cell differentiation in vivo
Samik Upadhaya, Catherine M. Sawai, E. Papalexi, A. Rashidfarrokhi +4 more
2018Journal of Experimental Medicine73 citations Open access
Semantic Scholar
JAK2/IDH-mutant–driven myeloproliferative neoplasm is sensitive to combined targeted inhibition
A. McKenney, Allison N. Lau, Amritha Varshini Hanasoge Somasundara, B. Spitzer +19 more
2018Journal of Clinical Investigation73 citations Open access
Semantic Scholar
Systematic reconstruction of molecular pathway signatures using scalable single-cell perturbation screens
Longda Jiang, Carol Dalgarno, E. Papalexi, Isabella Mascio +6 more
2024bioRxiv64 citations Open access
Semantic Scholar
A latent subset of human hematopoietic stem cells resists regenerative stress to preserve stemness
K. Kaufmann, Andy G. X. Zeng, É. Coyaud, Laura Garcia-Prat +14 more
2021Nature Immunology55 citations Open access
Semantic Scholar
Tumor-specific HSP90 inhibition as a therapeutic approach in JAK-mutant acute lymphoblastic leukemias.
N. Kucine, Sachie Marubayashi, Neha Bhagwat, E. Papalexi +21 more
2015Blood34 citations Open access
Semantic Scholar
High sensitivity single cell RNA sequencing with split pool barcoding
Vuong Tran, E. Papalexi, S. Schroeder, Grace Kim +13 more
2022bioRxiv32 citations Open access
Semantic Scholar
A single-cell cytokine dictionary of human peripheral blood
Lukas Oesinghaus, Sören Becker, L. Vornholz, E. Papalexi +24 more
2025bioRxiv15 citations Open access
Semantic Scholar
Expanding the CITE-seq tool-kit: Detection of proteins, transcriptomes, clonotypes and CRISPR perturbations with multiplexing, in a single assay
Eleni P. Mimitou, A. Cheng, A. Montalbano, S. Hao +10 more
2018bioRxiv14 citations Open access
Semantic Scholar
Jak1 Integrates Cytokine Sensing to Regulate Hematopoietic Stem Cell Function and Stress Hematopoiesis
M. Kleppe, M. Spitzer, Sheng Li, Corinne E. Hill +12 more
2018Cell Stem Cell12 citations Open access
Semantic Scholar
Reply to "Uveal melanoma cells are resistant to EZH2 inhibition regardless of BAP1 status"
Lindsay M. LaFave, W. Béguelin, R. Koche, Matt Teater +27 more
2016Nature Medicine8 citations
Semantic Scholar
JAK2/IDH-mutant-driven myeloproliferative neoplasm is sensitive to combined targeted inhibition.
A. McKenney, Allison N. Lau, Amritha Varshini Hanasoge Somasundara, B. Spitzer +19 more
2018Journal of Clinical Investigation6 citations Open access
Semantic Scholar
Tahoe-100M: Mapping drug-induced molecular phenotypes at single-cell resolution.
Jesse Zhang, Airol A. Ubas, Valentine Svensson, Nicole Thomas +36 more
2026Cell5 citations Open access
Semantic Scholar
JAK1 As a Convergent Regulator of Hematopoietic Stem Cell Function and Stress Hematopoiesis
M. Kleppe, M. Spitzer, Sheng Li, Lauren Dong +10 more
20164 citations
Semantic Scholar
FEM: mining biological meaning from cell level in single-cell RNA sequencing data
Yun-Qing Liu, Na Lu, Chang-Wei Bi, Ting-Yu Han +247 more
2021PeerJ3 citations Open access
Semantic Scholar
Characterizing the molecular regulation of inhibitory immune checkpoints with multi-modal single-cell screens
E. Papalexi, Eleni Mimitou, Andrew W. Butler, Samantha Foster +6 more
2020bioRxiv3 citations Open access
Semantic Scholar
The Genetic Control of Fat Body Development and Function in Drosophila melanogaster
E. Papalexi
20132 citations
Semantic Scholar
A Distinct Subset of Human Blood Stem Cells Resists Regenerative Stress to Preserve Stemness
K. Kaufmann, Andy G. X. Zeng, É. Coyaud, Laura Garcia-Prat +12 more
20201 citations
Semantic Scholar
BAP1 Loss Results in EZH2-Dependent Transformation in Myelodysplastic Syndromes
Lindsay M. LaFave, W. Béguelin, R. Koche, Matt Teater +11 more
20151 citations
Semantic Scholar
Rapid expansion and comprehensive profiling of lung tumor infiltrating lymphocytes using a highly scalable TCR sequencing method 2258388
E. Papalexi, Crina Curca, Ajay A. Sapre, Melad Askndafi +5 more
2026Journal of Immunology0 citations Open access
Semantic Scholar
Abstract 491: A 100 million cell single cell atlas enabling mechanistic and genotype-specific drug response discovery.
Aisling Sinclair, Joey Pangallo, Vuong K. Tran, E. Papalexi +17 more
2026Cancer Research0 citations
Semantic Scholar
135 Deep-mining antibody repertoires with sensitive, high-throughput single cell BCR and whole transcriptome sequencing
Ajay A. Sapre, Guillermo Gallareta-Olivares, Alec Salvino, E. Papalexi +4 more
2025Regular and Young Investigator Award Abstracts0 citations Open access
Semantic Scholar
Generating a 10 million cell atlas of immune responses to cytokine stimulation using high throughput single cell RNA sequencing 3845
E. Papalexi, Joey Pangallo, Simone Marrujo, Bryan Hariadi +18 more
2025Journal of Immunology0 citations
Semantic Scholar
A single-cell cytokine dictionary of human peripheral blood
Lukas Oesinghaus, Sören Becker, L. Vornholz, E. Papalexi +24 more
2025Research Square0 citations Open access
Semantic Scholar
941 A 10 million cell single cell atlas of cytokine-driven immune responses
Joey Pangallo, E. Papalexi, Simone Marrujo, Bryan Hariadi +17 more
2025Regular and Young Investigator Award Abstracts0 citations Open access
Semantic Scholar
Abstract LB106: Unleashing the power of AI-driven drug discovery with a 100 million single-cell atlas
Vuong K. Tran, E. Papalexi, Joey Pangallo, John D. Thompson +15 more
2025Cancer Research0 citations
Semantic Scholar
High-throughput single cell identification of virus-specific T cell receptors in common infectious diseases 4256
E. Papalexi, Crina Curca, Jose Jacob, Gary Geiss +2 more
2025Journal of Immunology0 citations
Semantic Scholar
824 Comprehensive single cell profiling of lung tumor infiltrating lymphocytes using high-throughput TCR sequencing
Karlie Fedder-Semmes, E. Papalexi, Crina Curca, Ajay A. Sapre +6 more
2025Regular and Young Investigator Award Abstracts0 citations Open access
Semantic Scholar
Deep-mining the antibody repertoires of transgenic mouse models with high-throughput single cell BCR and whole transcriptome sequencing 3955
Ajay A. Sapre, Alec Salvino, Guillermo Gallareta-Olivares, E. Papalexi +4 more
2025Journal of Immunology0 citations
Semantic Scholar
Abstract 4066: High throughput single-cell TCR sequencing method identifies cancer-specific TCR clonotypes
E. Papalexi, Crina Curca, Bryan Hariadi, Alexa Suyama +4 more
2025Cancer Research0 citations
Semantic Scholar
Abstract 4074: A 10 million cell atlas of cytokine-stimulated PBMCs via high-throughput combinatorial single cell RNA sequencing
Joey Pangallo, E. Papalexi, Simone Marrujo, Bryan Hariadi +15 more
2025Cancer Research0 citations
Semantic Scholar
860 Simultaneous profiling of one million single-cell BCRs and whole transcriptomes from diseased and healthy B cells in a single experiment using combinatorial barcoding
Guillermo Gallareta-Olivares, Ajay A. Sapre, E. Papalexi, Alec Salvino +4 more
2024Regular and Young Investigator Award Abstracts0 citations Open access
Semantic Scholar
Simultaneous profiling of single-cell BCR clonal diversity and whole transcriptomes from diseased and healthy PBMCs in a single experiment using split-pool combinatorial barcoding
Ajay A. Sapre, E. Papalexi, Alec Salvino, Simone Marrujo +3 more
2024Journal of Immunology0 citations
Semantic Scholar
Expanding the split-pool combinatorial barcoding toolkit to characterize the effects of aging in mouse TCR diversity.
E. Papalexi, Bryan Hariadi, Alexa Suyama, Crina Curca +2 more
2024Journal of Immunology0 citations
Semantic Scholar
Profiling antigen-reactive T cells using high throughput single-cell T cell receptor sequencing.
E. Papalexi, Bryan Hariadi, Crina Curca, Charles M. Roco +1 more
2024Journal of Immunology0 citations
Semantic Scholar

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