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Stefania Purgato · SciRah

Researcher profile · Semantic Scholar

Stefania Purgato

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Stefania Purgato — researcher profile on SciRah

h-index: 15
Works: 31
Citations: 1,669

Most-cited papers

Comparative and demographic analysis of orangutan genomes
Devin P. Locke, L. Hillier, W. Warren, K. Worley +98 more
2011Nature599 citations Open access
Semantic Scholar
Gene amplification as double minutes or homogeneously staining regions in solid tumors: origin and structure.
C. T. Storlazzi, A. Lonoce, M. C. Guastadisegni, D. Trombetta +12 more
2010Genome Research228 citations Open access
Semantic Scholar
Inhibition of polyamine synthesis and uptake reduces tumor progression and prolongs survival in mouse models of neuroblastoma
Laura D. Gamble, Stefania Purgato, J. Murray, Lin Xiao +29 more
2019Science Translational Medicine140 citations Open access
Semantic Scholar
p21Waf1/Cip1 is a common target induced by short-chain fatty acid HDAC inhibitors (valproic acid, tributyrin and sodium butyrate) in neuroblastoma cells.
P. Rocchi, R. Tonelli, Consuelo Camerin, Stefania Purgato +5 more
2005Oncology Report103 citations
Semantic Scholar
Genome-wide characterization of centromeric satellites from multiple mammalian genomes.
C. Alkan, M. F. Cardone, C. Catacchio, F. Antonacci +7 more
2011Genome Research98 citations Open access
Semantic Scholar
Anti-gene peptide nucleic acid specifically inhibits MYCN expression in human neuroblastoma cells leading to cell growth inhibition and apoptosis
R. Tonelli, Stefania Purgato, Consuelo Camerin, R. Fronza +9 more
2005Molecular Cancer Therapeutics94 citations
Semantic Scholar
Antitumor Activity of Sustained N-Myc Reduction in Rhabdomyosarcomas and Transcriptional Block by Antigene Therapy
R. Tonelli, A. McIntyre, Consuelo Camerin, Z. Walters +27 more
2011Clinical Cancer Research86 citations Open access
Semantic Scholar
Centromere sliding on a mammalian chromosome
Stefania Purgato, Elisa Belloni, Francesca M. Piras, M. Zoli +10 more
2014Chromosoma64 citations Open access
Semantic Scholar
MYC-Driven Neuroblastomas Are Addicted to a Telomerase-Independent Function of Dyskerin.
R. O'Brien, Sieu L. Tran, M. Maritz, Bing Liu +15 more
2016Cancer Research42 citations
Semantic Scholar
Epigenetic origin of evolutionary novel centromeres
D. Tolomeo, O. Capozzi, R. Stanyon, N. Archidiacono +9 more
2017Scientific Reports40 citations Open access
Semantic Scholar
Evolutionary descent of a human chromosome 6 neocentromere: a jump back to 17 million years ago.
O. Capozzi, Stefania Purgato, Pietro D 'addabbo, N. Archidiacono +6 more
2009Genome Research38 citations Open access
Semantic Scholar
Human centromere repositioning activates transcription and opens chromatin fibre structure
C. Naughton, C. Huidobro, C. Catacchio, Adam Buckle +5 more
2022Nature Communications27 citations Open access
Semantic Scholar
Evolutionary and clinical neocentromeres: two faces of the same coin?
O. Capozzi, Stefania Purgato, Ludovica Verdun di Cantogno, E. Grosso +4 more
2008Chromosoma22 citations
Semantic Scholar
Epigallocatechin-3-gallate Delivered in Nanoparticles Increases Cytotoxicity in Three Breast Carcinoma Cell Lines
F. Farabegoli, A. Granja, J. Magalhães, Stefania Purgato +2 more
2022ACS Omega20 citations Open access
Semantic Scholar
The Hidden Genomic and Transcriptomic Plasticity of Giant Marker Chromosomes in Cancer
G. Macchia, M. Severgnini, Stefania Purgato, D. Tolomeo +12 more
2017Genetics15 citations Open access
Semantic Scholar
MAX to MYCN intracellular ratio drives the aggressive phenotype and clinical outcome of high risk neuroblastoma.
F. Ferrucci, Roberto Ciaccio, S. Monticelli, Paolo Pigini +8 more
2018Biochimica et Biophysica Acta. Gene Regulatory Mechanisms12 citations Open access
Semantic Scholar
Ring chromosomes, breakpoint clusters, and neocentromeres in sarcomas
G. Macchia, K. H. Nord, M. Zoli, Stefania Purgato +7 more
2015Genes, Chromosomes and Cancer11 citations
Semantic Scholar
Repurposing a psychoactive drug for children with cancer: p27Kip1-dependent inhibition of metastatic neuroblastomas by Prozac
Sandra Bibbò, A. Lamolinara, E. Capone, Stefania Purgato +11 more
2020Oncogenesis9 citations Open access
Semantic Scholar
A G316A Polymorphism in the Ornithine Decarboxylase Gene Promoter Modulates MYCN-Driven Childhood Neuroblastoma
Laura D. Gamble, Stefania Purgato, M. Henderson, S. Di Giacomo +31 more
2021Cancers7 citations Open access
Semantic Scholar
The cell-permeable iron chelator M606 inhibits MYCN-driven neuroblastoma via an E2F3-mediated response
Ruby Pandher, Cheng-Yuan Xue, Laura D. Gamble, G. Milazzo +22 more
2025Proceedings of the National Academy of Sciences of the United States of America5 citations Open access
Semantic Scholar
Trisomy 11 with MLL‐PTD in a case of infant AML M0
S. Serravalle, Stefania Purgato, F. Melchionda, A. Astolfi +2 more
2007British Journal of Haematology3 citations Open access
Semantic Scholar
Author Correction: Comparative and demographic analysis of orang-utan genomes
Devin P. Locke, L. Hillier, W. Warren, K. Worley +97 more
2022Nature2 citations Open access
Semantic Scholar
Genome characterization and CRISPR-Cas9 editing of a human neocentromere
Antonio Palazzo, Ilaria Piccolo, C. Minervini, Stefania Purgato +6 more
2022Chromosoma1 citations Open access
Semantic Scholar
Human centromere formation activates transcription and opens chromatin fibre structure
C. Naughton, C. Huidobro, C. Catacchio, Adam Buckle +5 more
2021bioRxiv1 citations Open access
Semantic Scholar
Erratum to: Centromere sliding on a mammalian chromosome
Stefania Purgato, Elisa Belloni, Francesca M. Piras, M. Zoli +10 more
2014Chromosoma1 citations Open access
Semantic Scholar
Corrigendum to: "MAX to MYCN intracellular ratio drives the aggressive phenotype and clinical outcome of high risk neuroblastoma" [Biochim. Biophys. Acta, Gene Regul. Mech. 1861 (2018) 235-245].
F. Ferrucci, Roberto Ciaccio, S. Monticelli, Paolo Pigini +8 more
2020Biochimica et Biophysica Acta. Gene Regulatory Mechanisms0 citations
Semantic Scholar
The ornithine decarboxylase G316A promoter polymorphism impacts neuroblastoma clinical outcome and may identify patients particularly susceptible to polyamine inhibition
Laura D. Gamble, Stefania Purgato, S. Di Giacomo, Amanda J. Russell +16 more
20180 citations
Semantic Scholar
Abstract 488: High DKC1 expression supports neuroblastoma tumor cell proliferation and is strongly associated with poor patient outcomes
R. O'Brien, M. Maritz, C. Kong, Stefania Purgato +10 more
20150 citations
Semantic Scholar
Abstract 3808: MYCN coordinately regulates the entire polyamine gene pathway to drive polyamine biosynthesis in neuroblastoma, with expression of every synthetic and catabolic polyamine pathway gene being highly prognostic of clinical outcome.
M. Norris, Laura D. Gamble, J. Murray, Stefania Purgato +10 more
20130 citations
Semantic Scholar
Gene amplification as double minutes or hsr in solid tumors: origin and structure
G. Macchia, C. T. Storlazzi, A. Lonoce, Maria Corsignano Guastadisegni +11 more
20100 citations
Semantic Scholar
Trisomy 11 and Partial Tandem Duplication of the MLL Gene in a Case of Infant Acute Myeloid Leukemia M0.
S. Serravalle, Stefania Purgato, F. Melchionda, R. Tonelli +1 more
20050 citations
Semantic Scholar

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