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A. Balduini · SciRah

Researcher profile · Semantic Scholar

A. Balduini

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A. Balduini — researcher profile on SciRah

h-index: 41
Works: 168
Citations: 4,990

Most-cited papers

Differential clinical effects of different mutation subtypes in CALR-mutant myeloproliferative neoplasms
D. Pietra, E. Rumi, V. Ferretti, C. D. Di Buduo +16 more
2015Leukemia275 citations Open access
Semantic Scholar
Clinical and pathogenic features of ETV6-related thrombocytopenia with predisposition to acute lymphoblastic leukemia
F. Melazzini, Flavia Palombo, A. Balduini, D. De Rocco +18 more
2016Haematologica101 citations Open access
Semantic Scholar
Revealing eltrombopag’s promotion of human megakaryopoiesis through AKT/ERK-dependent pathway activation
C. D. Di Buduo, M. Currao, A. Pecci, D. Kaplan +2 more
2016Haematologica95 citations Open access
Semantic Scholar
The secret life of a megakaryocyte: emerging roles in bone marrow homeostasis control
Alessandro Malara, V. Abbonante, C. D. Di Buduo, Lorenzo Tozzi +2 more
2015Cellular and Molecular Life Sciences86 citations Open access
Semantic Scholar
Defective interaction of mutant calreticulin and SOCE in megakaryocytes from patients withmyeloproliferative neoplasms.
C. D. Di Buduo, V. Abbonante, C. Marty, F. Moccia +12 more
2019Blood65 citations Open access
Semantic Scholar
Multi-channel silk sponge mimicking bone marrow vascular niche for platelet production
Lorenzo Tozzi, P. Laurent, C. D. Di Buduo, X. Mu +5 more
2018Biomaterials63 citations Open access
Semantic Scholar
A new path to platelet production through matrix sensing
V. Abbonante, C. D. Di Buduo, C. Gruppi, C. De Maria +9 more
2017Haematologica59 citations Open access
Semantic Scholar
Megakaryocyte Contribution to Bone Marrow Fibrosis: many Arrows in the Quiver
Alessandro Malara, V. Abbonante, M. Zingariello, A. Migliaccio +1 more
2018Mediterranean Journal of Hematology and Infectious Diseases58 citations Open access
Semantic Scholar
Thrombopoietin/TGF‐β1 Loop Regulates Megakaryocyte Extracellular Matrix Component Synthesis
V. Abbonante, C. D. Di Buduo, C. Gruppi, Alessandro Malara +11 more
2016Stem Cells54 citations Open access
Semantic Scholar
Halting the vicious cycle within the multiple myeloma ecosystem: blocking JAM-A on bone marrow endothelial cells restores angiogenic homeostasis and suppresses tumor progression
Antonio Giovanni Solimando, M. da Via, P. Leone, P. Borrelli +27 more
2020Haematologica52 citations Open access
Semantic Scholar
Creation and implantation of acellular rat renal ECM-based scaffolds
A. Peloso, J. Ferrario, B. Maiga, I. Benzoni +11 more
2015Organogenesis52 citations Open access
Semantic Scholar
Three-dimensional printing of silk protein structures by aqueous solvent-directed molecular assembly
X. Mu, Yu Wang, Chengchen Guo, Yamin Li +10 more
2019Macromolecular Bioscience51 citations Open access
Semantic Scholar
The role of the extracellular matrix in primary myelofibrosis
O. Leiva, Seng Kah Ng, S. Chitalia, A. Balduini +2 more
2017Blood Cancer Journal51 citations Open access
Semantic Scholar
EDA fibronectin–TLR4 axis sustains megakaryocyte expansion and inflammation in bone marrow fibrosis
Alessandro Malara, C. Gruppi, V. Abbonante, D. Cattaneo +11 more
2019Journal of Experimental Medicine50 citations Open access
Semantic Scholar
β4GALT1 controls β1 integrin function to govern thrombopoiesis and hematopoietic stem cell homeostasis
Silvia Giannini, Melissa M. Lee-Sundlov, Leonardo Rivadeneyra, C. D. Di Buduo +5 more
2020Nature Communications45 citations Open access
Semantic Scholar
Stromal Cell-Derived Factor-1α Promotes Endothelial Colony-Forming Cell Migration Through the Ca2+-Dependent Activation of the Extracellular Signal-Regulated Kinase 1/2 and Phosphoinositide 3-Kinase/AKT Pathways
Estella Zuccolo, C. D. Di Buduo, F. Lodola, S. Orecchioni +8 more
2018Stem Cells and Development43 citations
Semantic Scholar
Mechanisms of thrombocytopenia in platelet-type von Willebrand disease
L. Bury, Alessandro Malara, S. Momi, E. Petito +2 more
2019Haematologica42 citations Open access
Semantic Scholar
Modular flow chamber for engineering bone marrow architecture and function
C. D. Di Buduo, P. Soprano, Lorenzo Tozzi, S. Marconi +3 more
2017Biomaterials38 citations Open access
Semantic Scholar
SLFN14-related thrombocytopenia: identification within a large series of patients with inherited thrombocytopenia
C. Marconi, C. D. Di Buduo, Serena Barozzi, Flavia Palombo +7 more
2016Thrombosis and Haemostasis38 citations
Semantic Scholar
Loss-of-function mutations in PTPRJ cause a new form of inherited thrombocytopenia.
C. Marconi, C. D. Di Buduo, K. LeVine, Serena Barozzi +14 more
2019Blood36 citations Open access
Semantic Scholar
Clinic, pathogenic mechanisms and drug testing of two inherited thrombocytopenias, ANKRD26-related Thrombocytopenia and MYH9-related diseases.
A. Balduini, H. Raslova, C. D. Di Buduo, A. Donada +3 more
2018European Journal of Medical Genetics36 citations
Semantic Scholar
Upregulation of lysyl oxidase and adhesion to collagen of human megakaryocytes and platelets in primary myelofibrosis.
V. Abbonante, V. Chitalia, V. Rosti, O. Leiva +3 more
2017Blood36 citations Open access
Semantic Scholar
Lack of COL6/collagen VI causes megakaryocyte dysfunction by impairing autophagy and inducing apoptosis
V. Abbonante, Alessandro Malara, Martina Chrisam, Samuele Metti +11 more
2022Autophagy35 citations Open access
Semantic Scholar
Recombinant Collagen Engineered to Bind to Discoidin Domain Receptor Functions as a Receptor Inhibitor
Bo An, V. Abbonante, Huifang Xu, Despoina Gavriilidou +7 more
2015Journal of Biological Chemistry34 citations Open access
Semantic Scholar
Oxidative stress and thromboxane-dependent platelet activation in inflammatory bowel disease: effects of anti-TNF-α treatment
A. Di Sabatino, F. Santilli, M. Guerci, P. Simeone +11 more
2016Thrombosis and Haemostasis30 citations
Semantic Scholar
Endothelial-to-Mesenchymal Transition in Bone Marrow and Spleen of Primary Myelofibrosis.
B. G. Erba, C. Gruppi, M. Corada, F. Pisati +7 more
2017American Journal of Pathology28 citations Open access
Semantic Scholar
TNF-α increases the membrane expression of the chemokine receptor CCR6 in thyroid tumor cells, but not in normal thyrocytes: potential role in the metastatic spread of thyroid cancer
F. Coperchini, P. Pignatti, Andrea Carbone, R. Bongianino +7 more
2016Tumor Biology27 citations
Semantic Scholar
Abnormal proplatelet formation and emperipolesis in cultured human megakaryocytes from gray platelet syndrome patients
C. D. Di Buduo, M. Alberelli, A. Glembostky, G. Podda +6 more
2016Scientific Reports27 citations Open access
Semantic Scholar
Hyaluronan based hydrogels provide an improved model to study megakaryocyte-matrix interactions
M. Currao, Alessandro Malara, C. D. Di Buduo, V. Abbonante +2 more
2015Experimental Cell Research27 citations Open access
Semantic Scholar
The AMPK-activator AICAR in thyroid cancer: effects on CXCL8 secretion and on CXCL8-induced neoplastic cell migration
O. Awwad, F. Coperchini, P. Pignatti, M. Denegri +7 more
2018Journal of Endocrinological Investigation24 citations
Semantic Scholar
Novel variants in GALE cause syndromic macrothrombocytopenia by disrupting glycosylation and thrombopoiesis
A. Marín-Quílez, C. D. Di Buduo, L. Díaz-Ajenjo, V. Abbonante +15 more
2022Blood23 citations Open access
Semantic Scholar
The Plant Hormone Abscisic Acid Is a Prosurvival Factor in Human and Murine Megakaryocytes*
Alessandro Malara, Chiara Fresia, C. D. Di Buduo, P. Soprano +5 more
2017Journal of Biological Chemistry22 citations Open access
Semantic Scholar
Altered fibronectin expression and deposition by myeloproliferative neoplasm‐derived mesenchymal stromal cells
V. Abbonante, C. Gruppi, P. Catarsi, M. Avanzini +4 more
2016British Journal of Haematology22 citations Open access
Semantic Scholar
Miniaturized 3D bone marrow tissue model to assess response to Thrombopoietin-receptor agonists in patients
C. D. Di Buduo, P. Laurent, Carlo Zaninetti, L. Lordier +11 more
2021eLife19 citations Open access
Semantic Scholar
Megakaryocyte Cytoskeletal Proteins in Platelet Biogenesis and Diseases
S. Mbiandjeu, A. Balduini, Alessandro Malara
2021Thrombosis and Haemostasis19 citations
Semantic Scholar
Functionalized 3D scaffolds for engineering the hematopoietic niche
M. Bruschi, Tania Vanzolini, Neety Sahu, A. Balduini +2 more
2022Frontiers in Bioengineering and Biotechnology18 citations Open access
Semantic Scholar
Latest culture techniques: cracking the secrets of bone marrow to mass-produce erythrocytes and platelets ex vivo
C. D. Di Buduo, A. Aguilar, P. Soprano, Alberto Bocconi +3 more
2021Haematologica18 citations Open access
Semantic Scholar
Translational approaches to functional platelet production ex vivo
A. Balduini, C. D. Di Buduo, D. Kaplan
2016Thrombosis and Haemostasis18 citations
Semantic Scholar
Bi-allelic variants in the ESAM tight-junction gene cause a neurodevelopmental disorder associated with fetal intracranial hemorrhage.
Mauro Lecca, D. Pehlivan, D. H. Suñer, K. Weiss +43 more
2023American Journal of Human Genetics17 citations Open access
Semantic Scholar
Adhesion to Fibronectin via α5β1 Integrin Supports Expansion of Megakaryocyte Lineage in Primary Myelofibrosis.
Shinobu Matsuura, C. Thompson, Seng Kah Ng, C. Ward +5 more
2020Blood16 citations Open access
Semantic Scholar
Pathophysiological Significance of Store-Operated Calcium Entry in Megakaryocyte Function: Opening New Paths for Understanding the Role of Calcium in Thrombopoiesis
C. D. Di Buduo, A. Balduini, F. Moccia
2016International Journal of Molecular Sciences16 citations Open access
Semantic Scholar
Reduced platelet glycoprotein Ibα shedding accelerates thrombopoiesis and COX-1 recovery: implications for aspirin dosing regimen
P. Simeone, R. Liani, Romina Tripaldi, S. Ciotti +18 more
2022Haematologica15 citations Open access
Semantic Scholar
Pathogenetic and clinical study of a patient with thrombocytopenia due to the p.E527K gain-of-function variant of SRC
Serena Barozzi, C. D. Di Buduo, C. Marconi, V. Bozzi +4 more
2020Haematologica15 citations Open access
Semantic Scholar
Sub-Cellular Localization of Metalloproteinases in Megakaryocytes
Alessandro Malara, D. Ligi, C. D. Di Buduo, F. Mannello +1 more
2018Cells15 citations Open access
Semantic Scholar
Studies of the interaction of ticagrelor with the P2Y13 receptor and with P2Y13-dependent pro-platelet formation by human megakaryocytes
Anna Björquist, C. D. Di Buduo, E. Femia, R. Storey +4 more
2016Thrombosis and Haemostasis15 citations Open access
Semantic Scholar
The spleen of patients with myelofibrosis harbors defective mesenchymal stromal cells
M. Avanzini, V. Abbonante, P. Catarsi, Irene Dambruoso +22 more
2018American journal of hematology/oncology14 citations Open access
Semantic Scholar
Three-Dimensional Tissue Models for Studying Ex Vivo Megakaryocytopoiesis and Platelet Production.
C. D. Di Buduo, V. Abbonante, Lorenzo Tozzi, D. Kaplan +1 more
2018Methods in molecular biology14 citations
Semantic Scholar
Inherited Thrombocytopenia Caused by Variants in Crucial Genes for Glycosylation
A. Marín-Quílez, L. Díaz-Ajenjo, C. D. Di Buduo, A. Zámora-Cánovas +6 more
2023International Journal of Molecular Sciences13 citations Open access
Semantic Scholar
Increased β4GALT1 expression associates with platelet surface galactosylation and thrombopoietin plasma levels in MPNs.
C. D. Di Buduo, Silvia Giannini, V. Abbonante, V. Rosti +2 more
2020Blood13 citations Open access
Semantic Scholar
A NEW FORM OF INHERITED THROMBOCYTOPENIA CAUSED BY LOSS-OF-FUNCTION MUTATIONS IN PTPRJ
C. Marconi, C. D. Di Buduo, K. LeVine, Serena Barozzi +16 more
201813 citations
Semantic Scholar

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