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N. Horeweg · SciRah

Researcher profile · Semantic Scholar

N. Horeweg

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N. Horeweg — researcher profile on SciRah

h-index: 22
Works: 123
Citations: 3,093

Most-cited papers

Prognostic refinement of NSMP high-risk endometrial cancers using oestrogen receptor immunohistochemistry
L. Vermij, J. Jobsen, A. Léon-Castillo, M. Brinkhuis +17 more
2022British Journal of Cancer182 citations Open access
Semantic Scholar
p53 immunohistochemistry in endometrial cancer: clinical and molecular correlates in the PORTEC-3 trial
L. Vermij, A. Léon-Castillo, Naveena Singh, M. Powell +33 more
2022Modern Pathology165 citations Open access
Semantic Scholar
Tertiary lymphoid structures critical for prognosis in endometrial cancer patients
N. Horeweg, H. Workel, Dominik Loiero, D. Church +17 more
2022Nature Communications131 citations Open access
Semantic Scholar
Interpretable deep learning model to predict the molecular classification of endometrial cancer from haematoxylin and eosin-stained whole-slide images: a combined analysis of the PORTEC randomised trials and clinical cohorts.
Sarah Fremond, S. Andani, J. Barkey Wolf, J. Dijkstra +20 more
2022The Lancet Digital Health129 citations Open access
Semantic Scholar
Prediction of recurrence risk in endometrial cancer with multimodal deep learning
S. Volinsky-Fremond, N. Horeweg, S. Andani, J. Barkey Wolf +21 more
2024Nature Medicine104 citations Open access
Semantic Scholar
Prognostic relevance of the molecular classification in high-grade endometrial cancer for patients staged by lymphadenectomy and without adjuvant treatment.
A. Léon-Castillo, N. Horeweg, E. Peters, T. Rutten +10 more
2022Gynecologic Oncology102 citations Open access
Semantic Scholar
Prevalence and Prognosis of Lynch Syndrome and Sporadic Mismatch Repair Deficiency in Endometrial Cancer
C. Post, E. Stelloo, V. Smit, D. Ruano +19 more
2021Journal of the National Cancer Institute91 citations Open access
Semantic Scholar
Molecular Classification Predicts Response to Radiotherapy in the Randomized PORTEC-1 and PORTEC-2 Trials for Early-Stage Endometrioid Endometrial Cancer
N. Horeweg, R. Nout, I. Jürgenliemk-Schulz, L. Lutgens +12 more
2023Journal of Clinical Oncology85 citations Open access
Semantic Scholar
Correlations between bone marrow radiation dose and hematologic toxicity in locally advanced cervical cancer patients receiving chemoradiation with cisplatin: a systematic review.
A. Corbeau, S. Kuipers, S. D. de Boer, N. Horeweg +3 more
2021Radiotherapy and Oncology68 citations Open access
Semantic Scholar
Molecular profile-based adjuvant treatment for women with high-intermediate risk endometrial cancer (PORTEC-4a): results of a randomised, open-label, phase 3, multicentre, non-inferiority trial.
A. S. V. D. van den Heerik, N. Horeweg, M. Haverkort, N. Kuijsters +26 more
2026The Lancet Oncology57 citations Open access
Semantic Scholar
Prognostic impact and causality of age on oncological outcomes in women with endometrial cancer: a multimethod analysis of the randomised PORTEC-1, PORTEC-2, and PORTEC-3 trials.
F. C. Wakkerman, Ji-Qing Wu, H. Putter, I. Jürgenliemk-Schulz +21 more
2024The Lancet Oncology34 citations Open access
Semantic Scholar
Clinical Behavior and Molecular Landscape of Stage I p53-Abnormal Low-Grade Endometrioid Endometrial Carcinomas
A. Jamieson, L. Vermij, C. H. Kramer, J. Jobsen +18 more
2023Clinical Cancer Research34 citations Open access
Semantic Scholar
QPOLE: A Quick, Simple, and Cheap Alternative for POLE Sequencing in Endometrial Cancer by Multiplex Genotyping Quantitative Polymerase Chain Reaction
A. S. V. D. van den Heerik, N. T. ter Haar, L. Vermij, J. Jobsen +16 more
2023JCO Global Oncology34 citations Open access
Semantic Scholar
PROTECT: Prospective Phase-II-Trial Evaluating Adaptive Proton Therapy for Cervical Cancer to Reduce the Impact on Morbidity and the Immune System
A. Corbeau, R. Nout, J. Mens, N. Horeweg +14 more
2021Cancers22 citations Open access
Semantic Scholar
The evolving role of morphology in endometrial cancer diagnostics: From histopathology and molecular testing towards integrative data analysis by deep learning
Sarah Fremond, V. Koelzer, N. Horeweg, T. Bosse
2022Frontiers in Oncology21 citations Open access
Semantic Scholar
Automated causal inference in application to randomized controlled clinical trials
Ji Wu, N. Horeweg, M. de Bruyn, R. Nout +9 more
2022Nature Machine Intelligence21 citations Open access
Semantic Scholar
A systematic review and meta-analysis of adjuvant chemotherapy after chemoradiation for locally advanced cervical cancer.
N. Horeweg, P. Mittal, P. Gradowska, I. Boere +2 more
2022Critical reviews in oncology/hematology19 citations Open access
Semantic Scholar
Adjuvant Systemic Therapy after Chemoradiation and Brachytherapy for Locally Advanced Cervical Cancer: A Systematic Review and Meta-Analysis
N. Horeweg, P. Mittal, P. Gradowska, I. Boere +2 more
2021Cancers19 citations Open access
Semantic Scholar
Microcystic elongated and fragmented (MELF) pattern of invasion: Molecular features and prognostic significance in the PORTEC-1 and -2 trials.
A. van den Heerik, K. Aiyer, E. Stelloo, I. Jürgenliemk-Schulz +8 more
2022Gynecologic Oncology17 citations Open access
Semantic Scholar
Assessment of patient symptom burden and information needs helps tailoring palliative care consultations: An observational study
M. Verhoef, Boudewijn Sweep, E. D. de Nijs, A. C. Valkenburg +4 more
2022European Journal of Cancer Care16 citations Open access
Semantic Scholar
Molecular and Clinicopathologic Characterization of Mismatch Repair-Deficient Endometrial Carcinoma Not Related to MLH1 Promoter Hypermethylation.
Merve Kaya, C. Post, C. Tops, M. Nielsen +17 more
2024Modern Pathology15 citations Open access
Semantic Scholar
Prognostic value of molecular classification in stage IV endometrial cancer
M. Uijterwaal, Dione van Dijk, C. Lok, C. D. de Kroon +7 more
2024International Journal of Gynecological Cancer12 citations Open access
Semantic Scholar
Clinical and Molecular Characteristics of High-Risk, Recurrent, or Metastatic Endometrial Cancer That Is Human Epidermal Growth Factor Receptor 2-Low.
Dione van Dijk, L. Vermij, A. Léon-Castillo, M. Powell +16 more
2024Journal of Clinical Oncology12 citations Open access
Semantic Scholar
Biomarker expression and impact on clinical outcomes in an international study of chemoradiation and MRI-based image-guided brachytherapy for locally advanced cervical cancer: BIOEMBRACE.
S. Chopra, T. Bosse, N. Horeweg, K. Deodhar +18 more
2024International Journal of Radiation Oncology, Biology, Physics12 citations Open access
Semantic Scholar
MR-based follow-up after brachytherapy and proton beam therapy in uveal melanoma
Michael C Y Tang, T. Ferreira, M. Marinkovic, M. Jaarsma-Coes +9 more
2023Neuroradiology11 citations Open access
Semantic Scholar
Vaginal brachytherapy management of stage I and II endometrial cancer
A. S. V. D. van den Heerik, N. Horeweg, C. Creutzberg, R. Nout
2022International Journal of Gynecological Cancer11 citations Open access
Semantic Scholar
Correction Method for Optical Scaling of Fundoscopy Images: Development, Validation, and First Implementation
L. Pors, Corné Haasjes, L. van Vught, Noor P. Hoes +6 more
2024Investigative Ophthalmology and Visual Science10 citations Open access
Semantic Scholar
Pattern of recurrence of the molecular subgroups in stage I high-grade endometrial cancer.
A. Léon-Castillo, N. Horeweg, E. Peters, N. T. ter Haar +9 more
2025Gynecologic Oncology9 citations Open access
Semantic Scholar
Clinicopathological and Molecular Characterization of High Grade Endometrial Carcinomas of No Specific Molecular Profile (NSMP) Stratified by ER Status
P. Timmermans, A. Léon-Castillo, Claire J H Kramer, N. T. ter Haar +8 more
2025International Journal of Gynecological Pathology9 citations Open access
Semantic Scholar
Clinical outcomes and risk factors for local failure and visual impairment in patients treated with Ru-106 brachytherapy for uveal melanoma
L. Pors, M. Marinkovic, H. H. Deuzeman, T. H. Vu +9 more
2025Clinical and Translational Radiation Oncology8 citations Open access
Semantic Scholar
Efficacy of PD-(L)1 inhibition in the treatment of endometrial cancer across molecular classes: a systematic review and meta-analysis.
Merve Kaya, M. Schaddelee, C. Creutzberg, J. Kroep +1 more
2025International Journal of Gynecological Cancer8 citations Open access
Semantic Scholar
397 Molecular profiling of NSMP high-risk endometrial cancers of the PORTEC-3 trial – prognostic refinement and druggable targets
L. Vermij, M. Powell, A. Léon-Castillo, S. D. de Boer +15 more
2021Endometrial cancer8 citations Open access
Semantic Scholar
595 Implementation of collaborative translational research (TransPORTEC) findings in an international endometrial cancer clinical trials program (RAINBO)
T. Bosse, M. Powell, E. Crosbie, A. Leary +16 more
2021Endometrial cancer8 citations Open access
Semantic Scholar
CCTG EN10: A phase II study of tailored adjuvant therapy in POLE-mutated and p53-wildtype/NSMP early-stage endometrial cancer (EC)—RAINBO BLUE and TAPER.
J. McAlpine, K. Han, M. Kinloch, M. Barkati +15 more
2023Journal of Clinical Oncology7 citations Open access
Semantic Scholar
The RAINBO MMRd-GREEN trial (GCIG/DGOG/ENGOT-EN142): A phase III trial on the addition of adjuvant durvalumab to radiotherapy in patients with high-risk MMRd endometrial cancer.
Merve Kaya, N. Horeweg, A. Leary, S. Welch +15 more
2023Journal of Clinical Oncology6 citations
Semantic Scholar
A protocol for evaluating robustness to H&E staining variation in computational pathology models
L. Schoenpflug, N. J. van den Berg, S. Andani, N. Horeweg +4 more
2026Journal of Pathology Informatics3 citations Open access
Semantic Scholar
POLARIX: POLE-mutation analysis by rapid image-based screening in endometrial cancer
N. J. van den Berg, L. Schoenpflug, N. Horeweg, S. Volinsky-Fremond +16 more
2026International Journal of Gynecological Cancer3 citations
Semantic Scholar
Cost-utility-analysis of molecular-integrated-profile for women with (high)intermediate risk endometrial cancer - PORTEC-4a an international, randomised, phase 3 trial.
A. S. V. D. van den Heerik, N. Horeweg, M. Haverkort, N. Kuijsters +26 more
2026Radiotherapy and Oncology3 citations Open access
Semantic Scholar
Survival benefit of cytoreductive surgery in patients with primary stage IV endometrial cancer: a systematic review & meta-analysis
E. Pham, N. Horeweg, J. van der Marel, L. Nooij
2024BJC Reports3 citations Open access
Semantic Scholar
2022-RA-743-ESGO Improving risk stratification for cervical cancer in patients treated with concurrent chemoradiation and MRI-image guided adaptive brachytherapy in EMBRACE study: results from an international collaborative translational research study (BIOEMBRACE-I)
S. Chopra, E. Jordanova, N. Horeweg, K. Deodhar +16 more
2022Cervical cancer3 citations Open access
Semantic Scholar
RB Loss in p53 Abnormal Endometrial Carcinoma: Histological and Clinicopathological Correlates.
Ezgi Dicle Serbes, N. Horeweg, Carlos Parra-Herrán, Renske van Rijnsoever +13 more
2024Modern Pathology2 citations Open access
Semantic Scholar
Author Correction: Prediction of recurrence risk in endometrial cancer with multimodal deep learning
S. Volinsky-Fremond, N. Horeweg, S. Andani, J. Barkey Wolf +21 more
2024Nature Medicine2 citations Open access
Semantic Scholar
Interpretable Deep Learning Predicts the Molecular Endometrial Cancer Classification from H&E Images: A Combined Analysis of the Portec Randomized Clinical Trials
Sarah Fremond, S. Andani, J. Barkey Wolf, J. Dijkstra +20 more
2022Social Science Research Network2 citations Open access
Semantic Scholar
EP116/#725 Low-grade p53abn endometrial carcinomas exist and are associated with a high risk of recurrence, even in low-stage disease
A. Jamieson, L. Vermij, Joseph Carlson, B. Howitt +10 more
2022E-Posters2 citations Open access
Semantic Scholar
1072 Large-scale Validation Confirms Lack of Prognostic Impact of Aberrant p53 Status in POLEmut and MMRd Endometrial Carcinoma
L. Vermij, J. Huvila, Amy Jamieson, J. McAlpine +17 more
2026Laboratory Investigation1 citations
Semantic Scholar
No prognostic role for FIGO grading in mismatch repair deficient endometrial carcinomas
F. C. Wakkerman, C. Post, G. Ortoft, Jan J. Jobsen +16 more
2026International Journal of Gynecological Cancer1 citations
Semantic Scholar
Prognostic Relevance of Molecular Classification in Endometrial Cancer: Insights From a South African Cohort.
R. Razack, E. D. Serbes, Michelle Cara Bryan-Mc Innes, J. Butt +5 more
2026JCO Global Oncology1 citations Open access
Semantic Scholar
5008 PORTEC-4a; an international randomised trial of molecular profile-based adjuvant treatment for women with high-intermediate risk endometrial cancer
A. S. V. D. van den Heerik, N. Horeweg, M. Haverkort, N. Kuijsters +21 more
2025Radiotherapy and Oncology1 citations
Semantic Scholar
Age-related differences in patient preferences for adjuvant chemotherapy for high-risk endometrial cancer.
F. C. Wakkerman, C. Post, J. Mens, I. Jürgenliemk-Schulz +16 more
2025Maturitas1 citations Open access
Semantic Scholar
Choroidal melanoma patient views on the importance of treatment characteristics and outcomes, and physicians' information provision in the Netherlands
A. Shirzada, A. Pieterse, L. Vlug, G. Luyten +7 more
2025Acta ophthalmologica1 citations Open access
Semantic Scholar

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