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F. Laliberté · SciRah

Researcher profile · Semantic Scholar

F. Laliberté

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F. Laliberté — researcher profile on SciRah

h-index: 16
Works: 24
Citations: 1,306

Most-cited papers

Slow- and tight-binding inhibitors of the 85-kDa human phospholipase A2.
Ian P. Street, Hung Lin, F. Laliberté, F. Ghomashchi +6 more
1993Biochemistry425 citations
Semantic Scholar
Deletion of phosphodiesterase 4D in mice shortens alpha(2)-adrenoceptor-mediated anesthesia, a behavioral correlate of emesis.
A. Robichaud, P. Stamatiou, S. Jin, N. Lachance +6 more
2002Journal of Clinical Investigation315 citations Open access
Semantic Scholar
Conformational difference between PDE4 apoenzyme and holoenzyme.
F. Laliberté, Yong-Xin Han, A. Govindarajan, A. Giroux +7 more
2000Biochemistry79 citations
Semantic Scholar
Dynamic Activation of Cystic Fibrosis Transmembrane Conductance Regulator by Type 3 and Type 4D Phosphodiesterase Inhibitors
Susana Liu, A. Veilleux, Lei Zhang, Andrew Young +7 more
2005Journal of Pharmacology and Experimental Therapeutics62 citations
Semantic Scholar
Optimization of a tertiary alcohol series of phosphodiesterase-4 (PDE4) inhibitors: structure-activity relationship related to PDE4 inhibition and human ether-a-go-go related gene potassium channel binding affinity.
R. Friesen, Y. Ducharme, R. Ball, M. Blouin +20 more
2003Journal of Medicinal Chemistry52 citations Open access
Semantic Scholar
Dissecting the cofactor-dependent and independent bindings of PDE4 inhibitors.
Susana Liu, F. Laliberté, B. Bobechko, Adrienne Bartlett +5 more
2001Biochemistry47 citations
Semantic Scholar
Discovery of L-791,943: a potent, selective, non emetic and orally active phosphodiesterase-4 inhibitor.
D. Guay, P. Hamel, M. Blouin, C. Brideau +13 more
2002Bioorganic & Medicinal Chemistry Letters43 citations Open access
Semantic Scholar
Continuous, vesicle-based fluorimetric assays of 14- and 85-kDa phospholipases A2.
Timothy Bayburt, Bao-Zhu Yu, I. Street, Farideh Ghomashchi +6 more
1995Analytical Biochemistry34 citations
Semantic Scholar
Targeting and Processing of Pro‐Opiomelanocortin in Neuronal Cell Lines
Gilles Noël, L. Zollinger, F. Laliberté, E. Rassart +2 more
1989Journal of Neurochemistry31 citations
Semantic Scholar
Substituted 4-(2,2-diphenylethyl)pyridine-N-oxides as phosphodiesterase-4 inhibitors: SAR study directed toward the improvement of pharmacokinetic parameters.
R. Frenette, M. Blouin, C. Brideau, N. Chauret +9 more
2002Bioorganic & Medicinal Chemistry Letters25 citations Open access
Semantic Scholar
Hunting the emesis and efficacy targets of PDE4 inhibitors: identification of the photoaffinity probe 8-(3-azidophenyl)-6- [(4-iodo-1H-1-imidazolyl)methyl]quinoline (APIIMQ).
D. Macdonald, H. Perrier, Susana Liu, F. Laliberté +4 more
2000Journal of Medicinal Chemistry25 citations Open access
Semantic Scholar
Discovery of a substituted 8-arylquinoline series of PDE4 inhibitors: structure-activity relationship, optimization, and identification of a highly potent, well tolerated, PDE4 inhibitor.
D. Macdonald, A. Mastracchio, H. Perrier, D. Dubé +29 more
2005Bioorganic & Medicinal Chemistry Letters24 citations Open access
Semantic Scholar
Human cytosolic phospholipase A2 expressed in insect cells is extensively phosphorylated on Ser-505.
Khalid Abdullah, W. Cromlish, Paul Payette, F. Laliberté +3 more
1995Biochimica et Biophysica Acta24 citations
Semantic Scholar
In vitro PKA phosphorylation‐mediated human PDE4A4 activation
F. Laliberté, Susana Liu, E. Gorseth, B. Bobechko +4 more
2002FEBS Letters22 citations Open access
Semantic Scholar
The discovery and synthesis of highly potent subtype selective phosphodiesterase 4D inhibitors.
Renée Aspiotis, D. Deschênes, D. Dubé, Y. Girard +6 more
2010Bioorganic & Medicinal Chemistry Letters21 citations Open access
Semantic Scholar
Optimization and structure-activity relationship of a series of 1-phenyl-1,8-naphthyridin-4-one-3-carboxamides: identification of MK-0873, a potent and effective PDE4 inhibitor.
D. Guay, L. Boulet, R. Friesen, M. Girard +8 more
2008Bioorganic & Medicinal Chemistry Letters20 citations Open access
Semantic Scholar
CDP840
M. J. Perry, James O’Connell, C. Walker, T. Crabbe +13 more
2007Cell Biochemistry and Biophysics16 citations
Semantic Scholar
Design, synthesis, and biological evaluation of 8-biarylquinolines: a novel class of PDE4 inhibitors.
M. Gallant, N. Chauret, D. Claveau, Stephen H. Day +18 more
2008Bioorganic & Medicinal Chemistry Letters11 citations Open access
Semantic Scholar
Substituted 2-pyridinemethanol derivatives as potent and selective phosphodiesterase-4 inhibitors.
Y. Ducharme, R. Friesen, M. Blouin, Bernard Côté +9 more
2003Bioorganic & Medicinal Chemistry Letters11 citations Open access
Semantic Scholar
Substituted furans as inhibitors of the PDE4 enzyme.
H. Perrier, C. Bayly, F. Laliberté, Zheng Huang +4 more
1999Bioorganic & Medicinal Chemistry Letters9 citations Open access
Semantic Scholar
Substituted aminopyridines as potent and selective phosphodiesterase-4 inhibitors.
Bernard Côté, R. Frenette, S. Prescott, M. Blouin +7 more
2003Bioorganic & Medicinal Chemistry Letters6 citations Open access
Semantic Scholar
Alkyl-bridged substituted 8-arylquinolines as highly potent PDE IV inhibitors.
P. Lacombe, N. Chauret, D. Claveau, Stephen H. Day +16 more
2009Bioorganic & Medicinal Chemistry Letters3 citations Open access
Semantic Scholar
Nitrogen-bridged substituted 8-arylquinolines as potent PDE IV inhibitors.
P. Lacombe, D. Deschênes, D. Dubé, L. Dubé +13 more
2006Bioorganic & Medicinal Chemistry Letters3 citations Open access
Semantic Scholar
Abstract 2766: Automation of linear range determination: Enzymatic progress curve applications
E. May, Daniel A Urul, S. Cornell-Kennon, Zhibing Lu +6 more
2023Cancer Research0 citations
Semantic Scholar

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