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F. Ghomashchi · SciRah

Researcher profile · Semantic Scholar

F. Ghomashchi

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F. Ghomashchi — researcher profile on SciRah

h-index: 36
Works: 64
Citations: 4,918

Most-cited papers

Slow- and tight-binding inhibitors of the 85-kDa human phospholipase A2.
Ian P. Street, Hung Lin, F. Laliberté, F. Ghomashchi +6 more
1993Biochemistry425 citations
Semantic Scholar
Interfacial Kinetic and Binding Properties of the Complete Set of Human and Mouse Groups I, II, V, X, and XII Secreted Phospholipases A2 *
A. Singer, F. Ghomashchi, C. Le Calvez, James Bollinger +7 more
2002Journal of Biological Chemistry339 citations Open access
Semantic Scholar
Serine 727 Phosphorylation and Activation of Cytosolic Phospholipase A2 by MNK1-related Protein Kinases*
Ying Hefner, A. Börsch-Haubold, M. Murakami, J. Wilde +12 more
2000Journal of Biological Chemistry234 citations Open access
Semantic Scholar
Exogenously Added Human Group X Secreted Phospholipase A2 but Not the Group IB, IIA, and V Enzymes Efficiently Release Arachidonic Acid from Adherent Mammalian Cells*
S. Bezzine, Rao S. Koduri, E. Valentin, M. Murakami +5 more
2000Journal of Biological Chemistry218 citations Open access
Semantic Scholar
Distinct Arachidonate-releasing Functions of Mammalian Secreted Phospholipase A2s in Human Embryonic Kidney 293 and Rat Mastocytoma RBL-2H3 Cells through Heparan Sulfate Shuttling and External Plasma Membrane Mechanisms*
M. Murakami, Rao S. Koduri, Ayako Enomoto, S. Shimbara +8 more
2001Journal of Biological Chemistry189 citations Open access
Semantic Scholar
Groups IV, V, and X Phospholipases A2s in Human Neutrophils
N. Degousée, F. Ghomashchi, E. Stefanski, A. Singer +11 more
2002Journal of Biological Chemistry183 citations Open access
Semantic Scholar
Novel Human Secreted Phospholipase A2 with Homology to the Group III Bee Venom Enzyme*
E. Valentin, F. Ghomashchi, M. Gelb, M. Lazdunski +1 more
2000Journal of Biological Chemistry183 citations Open access
Semantic Scholar
A protein geranylgeranyltransferase from bovine brain: implications for protein prenylation specificity.
K. Yokoyama, G. W. Goodwin, F. Ghomashchi, J. A. Glomset +1 more
1991Proceedings of the National Academy of Sciences of the United States of America181 citations Open access
Semantic Scholar
Tight binding inhibitors of 85-kDa phospholipase A2 but not 14-kDa phospholipase A2 inhibit release of free arachidonate in thrombin-stimulated human platelets.
F. Bártoli, Hung Lin, F. Ghomashchi, M. Gelb +2 more
1994Journal of Biological Chemistry171 citations Open access
Semantic Scholar
On the diversity of secreted phospholipases A(2). Cloning, tissue distribution, and functional expression of two novel mouse group II enzymes.
Emmanuel Valentin, F. Ghomashchi, M. Gelb, M. Lazdunski +1 more
1999Journal of Biological Chemistry170 citations Open access
Semantic Scholar
Cloning and Recombinant Expression of a Structurally Novel Human Secreted Phospholipase A2 *
M. Gelb, E. Valentin, F. Ghomashchi, M. Lazdunski +1 more
2000Journal of Biological Chemistry164 citations Open access
Semantic Scholar
Identification of Phosphorylation Sites of Human 85-kDa Cytosolic Phospholipase A 2 Expressed in Insect Cells and Present in Human Monocytes
M. D. de Carvalho, A. L. Mccormack, E. Olson, F. Ghomashchi +3 more
1996161 citations
Semantic Scholar
The inhibition of protein prenyltransferases by oxygenated metabolites of limonene and perillyl alcohol.
M. Gelb, F. Tamanoi, K. Yokoyama, F. Ghomashchi +2 more
1995Cancer Letters156 citations
Semantic Scholar
Arachidonic Acid Release from Mammalian Cells Transfected with Human Groups IIA and X Secreted Phospholipase A2 Occurs Predominantly during the Secretory Process and with the Involvement of Cytosolic Phospholipase A2-α*
C. Mounier, F. Ghomashchi, Margaret R. Lindsay, S. James +3 more
2004Journal of Biological Chemistry146 citations Open access
Semantic Scholar
A novel anti-inflammatory role for secretory phospholipase A2 in immune complex-mediated arthritis
É. Boilard, Y. Lai, Katherine S. Larabee, B. Balestrieri +13 more
2010EMBO Molecular Medicine140 citations Open access
Semantic Scholar
Recombinant production and properties of binding of the full set of mouse secreted phospholipases A2 to the mouse M-type receptor.
M. Rouault, C. Le Calvez, É. Boilard, Fanny Surrel +7 more
2007Biochemistry123 citations
Semantic Scholar
Interfacial Enzymology of Parvovirus Phospholipases A2*
S. Canaan, Z. Zádori, F. Ghomashchi, James Bollinger +4 more
2004Journal of Biological Chemistry115 citations Open access
Semantic Scholar
Binding of prenylated and polybasic peptides to membranes: affinities and intervesicle exchange.
F. Ghomashchi, Xiaohong Zhang, Li Liu, M. Gelb
1995Biochemistry109 citations
Semantic Scholar
Localization of Structural Elements of Bee Venom Phospholipase A2 Involved in N-type Receptor Binding and Neurotoxicity*
J. Nicolas, Ying-Wu Lin, G. Lambeau, F. Ghomashchi +2 more
1997Journal of Biological Chemistry108 citations Open access
Semantic Scholar
Conodipine-M, a Novel Phospholipase A2 Isolated from the Venom of the Marine Snail Conus magus(*)
J. M. McIntosh, F. Ghomashchi, M. Gelb, D. Dooley +4 more
1995Journal of Biological Chemistry106 citations Open access
Semantic Scholar
Cytosolic Phospholipase A2-α Is Necessary for Platelet-activating Factor Biosynthesis, Efficient Neutrophil-mediated Bacterial Killing, and the Innate Immune Response to Pulmonary Infection
B. Rubin, G. Downey, Adeline Koh, N. Degousée +17 more
2005Journal of Biological Chemistry94 citations Open access
Semantic Scholar
A pyrrolidine-based specific inhibitor of cytosolic phospholipase A(2)alpha blocks arachidonic acid release in a variety of mammalian cells.
F. Ghomashchi, A. Stewart, Ying Hefner, S. Ramanadham +3 more
2001Biochimica et Biophysica Acta92 citations Open access
Semantic Scholar
Phosphorylation of cytosolic phospholipase A2 in platelets is mediated by multiple stress-activated protein kinase pathways.
A. Börsch-Haubold, F. Ghomashchi, Sophie Pasquet, Michel Goedert +3 more
1999European Journal of Biochemistry78 citations Open access
Semantic Scholar
Cloning and recombinant expression of human group IIF-secreted phospholipase A(2).
Emmanuel Valentin, A. Singer, F. Ghomashchi, M. Lazdunski +2 more
2000Biochemical and Biophysical Research Communications - BBRC75 citations
Semantic Scholar
Trifluoromethyl ketones and methyl fluorophosphonates as inhibitors of group IV and VI phospholipases A(2): structure-function studies with vesicle, micelle, and membrane assays.
F. Ghomashchi, R. Loo, Jesús Balsinde, F. Bártoli +4 more
1999Biochimica et Biophysica Acta71 citations Open access
Semantic Scholar
Crystal Structure of Human Group X Secreted Phospholipase A2
Ying H. Pan, Bao-Zhu Yu, A. Singer, F. Ghomashchi +4 more
2002Journal of Biological Chemistry69 citations Open access
Semantic Scholar
Binding of the delta subunit to rod phosphodiesterase catalytic subunits requires methylated, prenylated C-termini of the catalytic subunits.
Terry A. Cook, F. Ghomashchi, M. Gelb, Stephanie K. Florio +1 more
2000Biochemistry63 citations
Semantic Scholar
Tandem Mass Spectrometry Has a Larger Analytical Range than Fluorescence Assays of Lysosomal Enzymes: Application to Newborn Screening and Diagnosis of Mucopolysaccharidoses Types II, IVA, and VI
A. Kumar, S. Masi, F. Ghomashchi, Naveen Kumar Chennamaneni +5 more
2015Clinical Chemistry59 citations Open access
Semantic Scholar
Basic residues of human group IIA phospholipase A2 are important for binding to factor Xa and prothrombinase inhibition comparison with other mammalian secreted phospholipases A2.
C. Mounier, P. Luchetta, Christelle Lecut, Rao S. Koduri +8 more
2000European Journal of Biochemistry55 citations Open access
Semantic Scholar
Function, Activity, and Membrane Targeting of Cytosolic Phospholipase A2ζ in Mouse Lung Fibroblasts*
M. Ghosh, Robyn Loper, F. Ghomashchi, D. E. Tucker +3 more
2007Journal of Biological Chemistry51 citations Open access
Semantic Scholar
Role of Phosphorylation and Basic Residues in the Catalytic Domain of Cytosolic Phospholipase A2α in Regulating Interfacial Kinetics and Binding and Cellular Function*
D. E. Tucker, M. Ghosh, F. Ghomashchi, Robyn Loper +6 more
2009Journal of Biological Chemistry50 citations Open access
Semantic Scholar
Interfacial binding of bee venom secreted phospholipase A2 to membranes occurs predominantly by a nonelectrostatic mechanism.
James G. Bollinger, Karthikeyan Diraviyam, F. Ghomashchi, D. Murray +1 more
2004Biochemistry48 citations
Semantic Scholar
Unusual Mode of Binding of Human Group IIA Secreted Phospholipase A2 to Anionic Interfaces as Studied by Continuous Wave and Time Domain Electron Paramagnetic Resonance Spectroscopy*
S. Canaan, Robert D. Nielsen, F. Ghomashchi, B. Robinson +1 more
2002Journal of Biological Chemistry46 citations Open access
Semantic Scholar
Secreted PLA2 group X orchestrates innate and adaptive immune responses to inhaled allergen.
J. Nolin, Y. Lai, H. Ogden, A. Manicone +10 more
2017JCI Insight36 citations Open access
Semantic Scholar
Matrix Metalloproteinase‐2 Negatively Regulates Cardiac Secreted Phospholipase A2 to Modulate Inflammation and Fever
Evan Berry, S. Hernández-Anzaldo, F. Ghomashchi, R. Lehner +5 more
2015Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease36 citations Open access
Semantic Scholar
Differentiation-dependent regulation of secreted phospholipases A2 in murine epidermis.
Silvia Gurrieri, G. Fürstenberger, A. Schadow, U. Haas +6 more
2003Journal of Investigative Dermatology36 citations Open access
Semantic Scholar
Interfacial Kinetic and Binding Properties of Mammalian Group IVB Phospholipase A2 (cPLA2β) and Comparison with the Other cPLA2 Isoforms*
F. Ghomashchi, Gajendra S. Naika, James G. Bollinger, A. Aloulou +3 more
2010Journal of Biological Chemistry32 citations Open access
Semantic Scholar
New Substrates and Enzyme Assays for the Detection of Mucopolysaccharidosis III (Sanfilippo Syndrome) Types A, B, C and D by Tandem Mass Spectrometry
Brian J. Wolfe, F. Ghomashchi, Tim M. Kim, Cynthia A. Abam +6 more
2012Bioconjugate chemistry27 citations Open access
Semantic Scholar
Group IVC cytosolic phospholipase A2gamma is farnesylated and palmitoylated in mammalian cells.
D. E. Tucker, A. Stewart, L. Nallan, Pravin M. Bendale +3 more
2005Journal of Lipid Research27 citations Open access
Semantic Scholar
The δ Subunit of Type 6 Phosphodiesterase Reduces Light-induced cGMP Hydrolysis in Rod Outer Segments*
T. A. Cook, F. Ghomashchi, M. Gelb, S. Florio +1 more
2001Journal of Biological Chemistry27 citations Open access
Semantic Scholar
Identification of Phosphorylation Sites of Human 85-kDa Cytosolic Phospholipase A Expressed in Insect Cells and Present in Human Monocytes (*)
M. D. de Carvalho, Ashley L. McCormack, E. Olson, F. Ghomashchi +3 more
1996Journal of Biological Chemistry27 citations Open access
Semantic Scholar
Liquid Chromatography-Tandem Mass Spectrometry Assay of Leukocyte Acid α-Glucosidase for Post-Newborn Screening Evaluation of Pompe Disease.
Na Lin, Jingyu Huang, S. Violante, Joseph J. Orsini +13 more
2017Clinical Chemistry26 citations Open access
Semantic Scholar
Lymphocyte Galactocerebrosidase Activity by Liquid Chromatography-Tandem Mass Spectrometry for Post-Newborn Screening Evaluation of Krabbe Disease
Hsuan-Chieh Liao, Zdenek Spacil, F. Ghomashchi, M. Escolar +5 more
2017Clinical Chemistry23 citations Open access
Semantic Scholar
Functional characterization of mutations in inherited human cPLA2 deficiency
Kathleen A. Reed, D. E. Tucker, A. Aloulou, D. Adler +5 more
2011Biochemistry21 citations Open access
Semantic Scholar
Protein prenyltransferases.
K. Yokoyama, G. W. Goodwin, F. Ghomashchi, J. Glomset +1 more
1992Biochemical Society Transactions20 citations
Semantic Scholar
Preparation of the Full Set of Recombinant Mouse- and Human-Secreted Phospholipases A2.
F. Ghomashchi, Vesna Brglez, C. Payré, Louise Jeammet +3 more
2017Methods in Enzymology18 citations Open access
Semantic Scholar
On the Diversity of Secreted Phospholipases A2
E. Valentin, F. Ghomashchi, M. Gelb, M. Lazdunski +1 more
1999Journal of Biological Chemistry18 citations Open access
Semantic Scholar
Interfacial catalysis by phospholipase A2: evaluation of the interfacial rate constants by steady-state isotope effect studies.
F. Ghomashchi, Thomas O'Hare, D. Clary, M. Gelb
1991Biochemistry14 citations
Semantic Scholar
Reliable Assay of Acid Sphingomyelinase Deficiency with the Mutation Q292K by Tandem Mass Spectrometry
F. Ghomashchi, M. Bárcenas, F. Tureček, C. R. Scott +1 more
2015Clinical Chemistry13 citations Open access
Semantic Scholar
Fluorimetric Assays for N-Acetylgalactosamine-6-Sulfatase and Arylsulfatase B Based on the Natural Substrates for Confirmation of Mucopolysaccharidoses Types IVA and VI
A. Kumar, Z. Spáčil, F. Ghomashchi, S. Masi +5 more
2015Clinica chimica acta; international journal of clinical chemistry12 citations Open access
Semantic Scholar

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D. E. Tucker — researcher profile on SciRah