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I. Anegon · SciRah

Researcher profile · Semantic Scholar

I. Anegon

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I. Anegon — researcher profile on SciRah

h-index: 61
Works: 337
Citations: 12K

Most-cited papers

CtIP fusion to Cas9 enhances transgene integration by homology-dependent repair
M. Charpentier, A. Khedher, S. Ménoret, A. Brion +12 more
2018Nature Communications199 citations Open access
Semantic Scholar
Targeting TMEM176B Enhances Antitumor Immunity and Augments the Efficacy of Immune Checkpoint Blockers by Unleashing Inflammasome Activation
Mercedes Segovia, S. Russo, M. Jeldres, Yamil D. Mahmoud +14 more
2019Cancer Cell142 citations Open access
Semantic Scholar
Immunoregulatory properties of the cytokine IL-34
C. Guillonneau, Séverine Bézie, I. Anegon
2017Cellular and Molecular Life Sciences98 citations Open access
Semantic Scholar
Future prospects for CD8+ regulatory T cells in immune tolerance
Léa Flippe, Séverine Bézie, I. Anegon, C. Guillonneau
2019Immunological Reviews83 citations Open access
Semantic Scholar
Generation of gene-edited rats by delivery of CRISPR/Cas9 protein and donor DNA into intact zygotes using electroporation
S. Remy, Vanessa Chenouard, L. Tesson, C. Usal +10 more
2017Scientific Reports83 citations Open access
Semantic Scholar
Characterization of Kcnk3-Mutated Rat, a Novel Model of Pulmonary Hypertension.
M. Lambert, V. Capuano, Angèle Boet, L. Tesson +15 more
2019Circulation Research79 citations Open access
Semantic Scholar
Human CD8+ Tregs expressing a MHC-specific CAR display enhanced suppression of human skin rejection and GVHD in NSG mice.
Séverine Bézie, B. Charreau, N. Vimond, Juliette Lasselin +6 more
2019Blood Advances69 citations Open access
Semantic Scholar
Ex Vivo Expanded Human Non-Cytotoxic CD8+CD45RClow/− Tregs Efficiently Delay Skin Graft Rejection and GVHD in Humanized Mice
Séverine Bézie, D. Meistermann, Laetitia Boucault, Stéphanie Kilens +10 more
2018Frontiers in Immunology69 citations Open access
Semantic Scholar
Heme Oxygenase-1 Modulates Human Respiratory Syncytial Virus Replication and Lung Pathogenesis during Infection
Janyra A. Espinoza, Miguel A. León, P. Céspedes, Roberto S. Gómez +11 more
2017Journal of Immunology63 citations Open access
Semantic Scholar
Super-Treg: Toward a New Era of Adoptive Treg Therapy Enabled by Genetic Modifications
L. Amini, Jenny A. Greig, M. Schmueck-Henneresse, H. Volk +5 more
2021Frontiers in Immunology53 citations Open access
Semantic Scholar
Advances on CD8+ Treg Cells and Their Potential in Transplantation.
Séverine Bézie, I. Anegon, C. Guillonneau
2018Transplantation53 citations Open access
Semantic Scholar
Transient antibody targeting of CD45RC induces transplant tolerance and potent antigen-specific regulatory T cells.
Elodie Picarda, Séverine Bézie, Laetitia Boucault, E. Autrusseau +9 more
2017JCI Insight48 citations Open access
Semantic Scholar
Role of indoleamine 2,3-dioxygenase in testicular immune-privilege
G. Gualdoni, P. Jacobo, C. Sobarzo, C. Pérez +7 more
2019Scientific Reports47 citations Open access
Semantic Scholar
IL‐34 and CSF‐1, deciphering similarities and differences at steady state and in diseases
A. Freuchet, A. Salama, S. Remy, C. Guillonneau +1 more
2021Journal of Leukocyte Biology46 citations
Semantic Scholar
Advances in Genome Editing and Application to the Generation of Genetically Modified Rat Models
Vanessa Chenouard, S. Remy, L. Tesson, S. Ménoret +3 more
2021Frontiers in Genetics44 citations Open access
Semantic Scholar
Multispecific Antibody Development Platform Based on Human Heavy Chain Antibodies
S. Clarke, B. Ma, N. Trinklein, U. Schellenberger +18 more
2019Frontiers in Immunology42 citations Open access
Semantic Scholar
Characterization of two rat models of cystic fibrosis—KO and F508del CFTR—Generated by Crispr‐Cas9
E. Dréano, M. Bacchetta, Juliette L Simonin, L. Galmiche +12 more
2019Animal Models and Experimental Medicine36 citations Open access
Semantic Scholar
Humanization of Immunodeficient Animals for the Modeling of Transplantation, Graft Versus Host Disease, and Regenerative Medicine
G. Adigbli, S. Ménoret, A. Cross, J. Hester +2 more
2020Transplantation34 citations Open access
Semantic Scholar
Multiplex CRISPR/Cas9 system impairs HCMV replication by excising an essential viral gene
J. Gergen, F. Coulon, A. Crénéguy, Nathan Elain-Duret +7 more
2018PLoS ONE34 citations Open access
Semantic Scholar
Breakdown of Immune Tolerance in AIRE-Deficient Rats Induces a Severe Autoimmune Polyendocrinopathy–Candidiasis–Ectodermal Dystrophy–like Autoimmune Disease
J. Ossart, A. Moreau, E. Autrusseau, S. Ménoret +11 more
2018Journal of Immunology30 citations Open access
Semantic Scholar
Comparison of Human and Experimental Pulmonary Veno-Occlusive Disease.
G. Manaud, E. Nossent, M. Lambert, M. Ghigna +28 more
2020American Journal of Respiratory Cell and Molecular Biology29 citations Open access
Semantic Scholar
Characterization of brain dystrophins absence and impact in dystrophin-deficient Dmdmdx rat model
D. Caudal, Virginie François, A. Lafoux, M. Ledevin +4 more
2020PLoS ONE27 citations Open access
Semantic Scholar
Generation of Immunodeficient Rats With Rag1 and Il2rg Gene Deletions and Human Tissue Grafting Models
S. Ménoret, L. Ouisse, L. Tesson, F. Delbos +14 more
2018Transplantation27 citations
Semantic Scholar
IL-34 Actions on FOXP3+ Tregs and CD14+ Monocytes Control Human Graft Rejection
Séverine Bézie, A. Freuchet, Céline Sérazin, A. Salama +3 more
2020Frontiers in Immunology26 citations Open access
Semantic Scholar
Cardiovascular phenotype of the Dmdmdx rat – a suitable animal model for Duchenne muscular dystrophy
P. L. Szabó, J. Ebner, Xaver Koenig, O. Hamza +11 more
2021Disease Models & Mechanisms24 citations Open access
Semantic Scholar
Otoferlin gene editing in sheep via CRISPR-assisted ssODN-mediated Homology Directed Repair
A. Menchaca, P. D. dos Santos-Neto, M. Souza-Neves, F. Cuadro +8 more
2020Scientific Reports24 citations Open access
Semantic Scholar
Generation of Double-Muscled Sheep and Goats by CRISPR /Cas9-Mediated Knockout of the Myostatin Gene.
P. Kalds, M. Crispo, Chao Li, L. Tesson +4 more
2022Methods in molecular biology23 citations
Semantic Scholar
In Vivo Analysis of Human Immune Responses in Immunodeficient Rats
S. Ménoret, L. Ouisse, L. Tesson, S. Remy +8 more
2019Transplantation23 citations Open access
Semantic Scholar
CRISPR/Cas9-mediated inactivation of the phosphatase activity of soluble epoxide hydrolase prevents obesity and cardiac ischemic injury
M. Leuillier, T. Duflot, S. Ménoret, H. Messaoudi +40 more
2022Journal of Advanced Research22 citations Open access
Semantic Scholar
Immunophenotype of a Rat Model of Duchenne's Disease and Demonstration of Improved Muscle Strength After Anti-CD45RC Antibody Treatment
L. Ouisse, S. Remy, A. Lafoux, T. Larcher +13 more
2019Frontiers in Immunology22 citations Open access
Semantic Scholar
Interleukin 27 is a novel cytokine with anti-inflammatory effects against spondyloarthritis through the suppression of Th17 responses
Q. Jouhault, B. Cherqaoui, A. Jobart-Malfait, S. Glatigny +15 more
2023Frontiers in Immunology20 citations Open access
Semantic Scholar
Evaluation of an AAV9-mini-dystrophin gene therapy candidate in a rat model of Duchenne muscular dystrophy
C. Le Guiner, Xiao Xiao, T. Larcher, A. Lafoux +13 more
2023Molecular Therapy: Methods & Clinical Development19 citations Open access
Semantic Scholar
PD-1/PD-L1 blockade abrogates a dysfunctional innate-adaptive immune axis in critical β-coronavirus disease
Maite Duhalde Vega, D. Olivera, Gustavo Gastão Davanzo, M. Bertullo +26 more
2022Science Advances18 citations Open access
Semantic Scholar
Regenerative cell therapy for the treatment of hyperbilirubinemic Gunn rats with fresh and frozen human induced pluripotent stem cells‐derived hepatic stem cells
Angélique Fourrier, F. Delbos, S. Ménoret, C. Collet +11 more
2019Xenotransplantation17 citations Open access
Semantic Scholar
TRPC3, but not TRPC1, as a good therapeutic target for standalone or complementary treatment of DMD
A. Creisméas, C. Gazaille, A. Bourdon, Marc-Antoine Lallemand +11 more
2021Journal of Translational Medicine16 citations Open access
Semantic Scholar
Transient antibody targeting of CD45RC inhibits the development of graft-versus-host disease.
Laetitia Boucault, María Dolores López Robles, A. Thiolat, Séverine Bézie +16 more
2020Blood Advances16 citations Open access
Semantic Scholar
Ceruloplasmin deficiency does not induce macrophagic iron overload: lessons from a new rat model of hereditary aceruloplasminemia
M. Kenawi, E. Rouger, M. Island, P. Leroyer +10 more
2019The FASEB Journal16 citations
Semantic Scholar
Evaluation of the dystrophin carboxy-terminal domain for micro-dystrophin gene therapy in cardiac and skeletal muscles in the DMDmdx rat model
A. Bourdon, Virginie François, Liwen Zhang, A. Lafoux +24 more
2022Gene Therapy15 citations Open access
Semantic Scholar
IL‐34 deficiency impairs FOXP3+ Treg function in a model of autoimmune colitis and decreases immune tolerance homeostasis
A. Freuchet, A. Salama, Séverine Bézie, L. Tesson +16 more
2022Clinical and Translational Medicine15 citations Open access
Semantic Scholar
Genetic engineering of human and mouse CD4+ and CD8+ Tregs using lentiviral vectors encoding chimeric antigen receptors
N. Vimond, Juliette Lasselin, I. Anegon, C. Guillonneau +1 more
2020Molecular Therapy: Methods & Clinical Development15 citations Open access
Semantic Scholar
Patients With Severe Multiple Sclerosis Exhibit Functionally Altered CD8+ Regulatory T Cells
Naïl Benallegue, Bryan Nicol, Juliette Lasselin, Séverine Bézie +9 more
2022Neurology: Neuroimmunology & Neuroinflammation13 citations Open access
Semantic Scholar
Genetic Restoration of Heme Oxygenase-1 Expression Protects from Type 1 Diabetes in NOD Mice
Julien Pogu, S. Tzima, G. Kollias, I. Anegon +2 more
2019International Journal of Molecular Sciences13 citations Open access
Semantic Scholar
Multimodality imaging and transciptomics to phenotype mitral valve dystrophy in a unique knock-in Filamin-A rat model.
C. Delwarde, C. Toquet, P. Aumond, A. Kayvanjoo +21 more
2022Cardiovascular Research10 citations Open access
Semantic Scholar
Anti-CD45RC antibody immunotherapy prevents and treats experimental autoimmune polyendocrinopathy–candidiasis–ectodermal dystrophy syndrome
Marine Besnard, Céline Sérazin, J. Ossart, A. Moreau +12 more
2022Journal of Clinical Investigation10 citations Open access
Semantic Scholar
CD4+ and CD8+ regulatory T cell characterization in the rat using a unique transgenic Foxp3-EGFP model
S. Ménoret, L. Tesson, S. Remy, V. Gourain +11 more
2023BMC Biology9 citations Open access
Semantic Scholar
Generation of CD34+CD43+ Hematopoietic Progenitors to Induce Thymocytes from Human Pluripotent Stem Cells
Léa Flippe, A. Gaignerie, Céline Sérazin, Olivier Baron +4 more
2021bioRxiv9 citations Open access
Semantic Scholar
A variant of ASIC2 mediates sodium retention in nephrotic syndrome
M. Fila, A. Sassi, G. Brideau, L. Cheval +15 more
2021JCI Insight9 citations Open access
Semantic Scholar
Excess of guide RNA reduces knockin efficiency and drastically increases on-target large deletions.
Vanessa Chenouard, Isabelle Leray, L. Tesson, S. Remy +9 more
2023iScience8 citations Open access
Semantic Scholar
Changes in social behavior with MAPK2 and KCTD13/CUL3 pathways alterations in two new outbred rat models for the 16p11.2 syndromes with autism spectrum disorders
Sandra Martin Lorenzo, Maria del Mar Muniz Moreno, Helin Atas, M. Pellen +11 more
2023Frontiers in Neuroscience7 citations Open access
Semantic Scholar
Overexpression of endothelial β3‐adrenergic receptor induces diastolic dysfunction in rats
J. Dhot, M. Ferron, Valentine Prat, A. Persello +19 more
2020ESC Heart Failure7 citations Open access
Semantic Scholar

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