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A. Pugsley · SciRah

Researcher profile · Semantic Scholar

A. Pugsley

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A. Pugsley — researcher profile on SciRah

h-index: 65
Works: 223
Citations: 13K

Most-cited papers

Type II protein secretion and its relationship to bacterial type IV pili and archaeal flagella.
Christopher R Peabody, Y. Chung, M. Yen, D. Vidal-Ingigliardi +2 more
2003Microbiology403 citations Open access
Semantic Scholar
Insertion of an outer membrane protein in Escherichia coli requires a chaperone‐like protein.
K. Hardie, S. Lory, A. Pugsley
1996EMBO Journal261 citations Open access
Semantic Scholar
Pilus formation and protein secretion by the same machinery in Escherichia coli
N. Sauvonnet, Guillaume Vignon, A. Pugsley, P. Gounon
2000EMBO Journal250 citations Open access
Semantic Scholar
Secretin PulD: association with pilot PulS, structure, and ion-conducting channel formation.
Nico Nouwen, N. Ranson, H. Saibil, Bettina Wolpensinger +3 more
1999Proceedings of the National Academy of Sciences of the United States of America215 citations Open access
Semantic Scholar
Testing the ‘+2 rule’ for lipoprotein sorting in the Escherichia coli cell envelope with a new genetic selection
A. Seydel, P. Gounon, A. Pugsley
1999Molecular Microbiology206 citations
Semantic Scholar
Secretion by numbers: protein traffic in prokaryotes
A. Economou, Peter J. Christie, R. Fernandez, T. Palmer +2 more
2006Molecular Microbiology161 citations Open access
Semantic Scholar
Structural Insights into the Secretin PulD and Its Trypsin-resistant Core*
M. Chami, I. Guilvout, Marco Gregorini, H. Rémigy +5 more
2005Journal of Biological Chemistry155 citations Open access
Semantic Scholar
Multiple Interactions between Pullulanase Secreton Components Involved in Stabilization and Cytoplasmic Membrane Association of PulE
O. Possot, G. Vignon, Natalia Bomchil, F. Ebel +1 more
2000Journal of Bacteriology152 citations Open access
Semantic Scholar
Expression of the endogenous type II secretion pathway in Escherichia coli leads to chitinase secretion
O. Francetic, D. Belin, C. Badaut, A. Pugsley
2000EMBO Journal148 citations Open access
Semantic Scholar
Domain structure of secretin PulD revealed by limited proteolysis and electron microscopy
N. Nouwen, H. Stahlberg, A. Pugsley, A. Engel
2000EMBO Journal142 citations Open access
Semantic Scholar
Type IV-Like Pili Formed by the Type II Secreton: Specificity, Composition, Bundling, Polar Localization, and Surface Presentation of Peptides
G. Vignon, R. Köhler, E. Larquet, Stéphanie Giroux +3 more
2003Journal of Bacteriology134 citations Open access
Semantic Scholar
Bacterial outer membrane secretin PulD assembles and inserts into the inner membrane in the absence of its pilotin
I. Guilvout, M. Chami, A. Engel, A. Pugsley +1 more
2006EMBO Journal132 citations Open access
Semantic Scholar
Molecular characterization of PulE, a protein required for pullulanase secretion
O. Possot, A. Pugsley
1994Molecular Microbiology126 citations
Semantic Scholar
The secretin‐specific, chaperone‐like protein of the general secretory pathway: separation of proteolytic protection and piloting functions
K. Hardie, A. Seydel, I. Guilvout, A. Pugsley
1996Molecular Microbiology118 citations
Semantic Scholar
Recent progress and future directions in studies of the main terminal branch of the general secretory pathway in Gram-negative bacteria--a review.
A. Pugsley, O. Francetic, O. Possot, N. Sauvonnet +1 more
1997Gene117 citations
Semantic Scholar
Structure and assembly of the pseudopilin PulG
R. Köhler, Karsten Schäfer, S. Müller, G. Vignon +6 more
2004Molecular Microbiology114 citations Open access
Semantic Scholar
Transcription and expression analysis, using lacZ and phoA gene fusions, of Mycobacterium fortuitumβ‐lactamase genes cloned from a natural isolate and a high‐level β‐lactamase producer
Juliano Timm, M. Perilli, C. Duez, J. Trias +8 more
1994Molecular Microbiology109 citations Open access
Semantic Scholar
Minor pseudopilin self‐assembly primes type II secretion pseudopilus elongation
David A. Cisneros, P. Bond, A. Pugsley, M. Campos +1 more
2011EMBO Journal104 citations Open access
Semantic Scholar
The C‐terminal domain of the secretin PulD contains the binding site for its cognate chaperone, PulS, and confers PulS dependence on pIVf1 function
S. Daefler, I. Guilvout, K. Hardie, A. Pugsley +1 more
1997Molecular Microbiology103 citations Open access
Semantic Scholar
Depletion of Apolipoprotein N-Acyltransferase Causes Mislocalization of Outer Membrane Lipoproteins in Escherichia coli*
Carine Robichon, D. Vidal-Ingigliardi, A. Pugsley
2005Journal of Biological Chemistry102 citations Open access
Semantic Scholar
Genetic Dissection of the Outer Membrane Secretin PulD: Are There Distinct Domains for Multimerization and Secretion Specificity?
I. Guilvout, K. Hardie, N. Sauvonnet, A. Pugsley
1999Journal of Bacteriology99 citations Open access
Semantic Scholar
The cryptic general secretory pathway (gsp) operon of Escherichia coli K-12 encodes functional proteins
O. Francetic, A. Pugsley
1996Journal of Bacteriology93 citations Open access
Semantic Scholar
Identification of two regions of Klebsiella oxytoca pullulanase that together are capable of promoting β‐lactamase secretion by the general secretory pathway
N. Sauvonnet, A. Pugsley
1996Molecular Microbiology89 citations
Semantic Scholar
Remodeling a DNA-binding protein as a specific in vivo inhibitor of bacterial secretin PulD
B. Mouratou, F. Schaeffer, I. Guilvout, Diana Tello-Manigne +3 more
2007Proceedings of the National Academy of Sciences of the United States of America88 citations Open access
Semantic Scholar
PpdD Type IV Pilin of Escherichia coliK-12 Can Be Assembled into Pili in Pseudomonas aeruginosa
N. Sauvonnet, P. Gounon, A. Pugsley
2000Journal of Bacteriology78 citations Open access
Semantic Scholar
Signal Recognition Particle-Dependent Inner Membrane Targeting of the PulG Pseudopilin Component of a Type II Secretion System
O. Francetic, N. Buddelmeijer, S. Lewenza, C. Kumamoto +1 more
2006Journal of Bacteriology75 citations Open access
Semantic Scholar
Novel Inner Membrane Retention Signals in Pseudomonas aeruginosa Lipoproteins
S. Lewenza, M. Mhlanga, A. Pugsley
2008Journal of Bacteriology74 citations Open access
Semantic Scholar
Energy requirement for pullulanase secretion by the main terminal branch of the general secretory pathway
Odile M. Possot, L. Letellier, A. Pugsley
1997Molecular Microbiology73 citations Open access
Semantic Scholar
In vitro multimerization and membrane insertion of bacterial outer membrane secretin PulD.
I. Guilvout, M. Chami, C. Berrier, A. Ghazi +3 more
2008Journal of Molecular Biology72 citations
Semantic Scholar
Secretins take shape
N. Bayan, I. Guilvout, A. Pugsley
2006Molecular Microbiology69 citations Open access
Semantic Scholar
Direct Visualization of Red Fluorescent Lipoproteins Indicates Conservation of the Membrane Sorting Rules in the Family Enterobacteriaceae
S. Lewenza, D. Vidal-Ingigliardi, A. Pugsley
2006Journal of Bacteriology68 citations
Semantic Scholar
Type III Protein Translocase
C. Pozidis, Aggeliki Chalkiadaki, Amalia Gomez-Serrano, H. Stahlberg +11 more
2003Journal of Biological Chemistry68 citations Open access
Semantic Scholar
Towards the Identification of Type II Secretion Signals in a Nonacylated Variant of Pullulanase from Klebsiella oxytoca
O. Francetic, A. Pugsley
2005Journal of Bacteriology64 citations Open access
Semantic Scholar
YaeT‐independent multimerization and outer membrane association of secretin PulD
Séverine Collin, I. Guilvout, M. Chami, A. Pugsley
2007Molecular Microbiology62 citations
Semantic Scholar
Sorting of an integral outer membrane protein via the lipoprotein‐specific Lol pathway and a dedicated lipoprotein pilotin
Séverine Collin, I. Guilvout, N. Nickerson, A. Pugsley
2011Molecular Microbiology61 citations
Semantic Scholar
Type III protein translocase: HrcN is a peripheral ATPase that is activated by oligomerization.
C. Pozidis, Aggeliki Chalkiadaki, Amalia Gomez-Serrano, H. Stahlberg +11 more
2003Journal of Biological Chemistry58 citations
Semantic Scholar
Multimers of the precursor of a type IV pilin‐like component of the general secretory pathway are unrelated to pili
A. Pugsley
1996Molecular Microbiology58 citations
Semantic Scholar
Membrane Association and Multimerization of Secreton Component PulC
O. Possot, Manon Gérard-Vincent, A. Pugsley
1999Journal of Bacteriology54 citations Open access
Semantic Scholar
Type II Secretion System Secretin PulD Localizes in Clusters in the Escherichia coli Outer Membrane
N. Buddelmeijer, M. Krehenbrink, F. Pecorari, A. Pugsley
2008Journal of Bacteriology53 citations Open access
Semantic Scholar
Outer Membrane Targeting of Pseudomonas aeruginosa Proteins Shows Variable Dependence on the Components of Bam and Lol Machineries
H. Hoàng, N. Nickerson, Vincent T. Lee, A. Kazimirova +3 more
2011mBio48 citations Open access
Semantic Scholar
Artificial binding proteins (Affitins) as probes for conformational changes in secretin PulD.
M. Krehenbrink, M. Chami, I. Guilvout, P. Alzari +2 more
2008Journal of Molecular Biology46 citations
Semantic Scholar
Coupled cell-free synthesis and lipid vesicle insertion of a functional oligomeric channel MscL MscL does not need the insertase YidC for insertion in vitro.
C. Berrier, I. Guilvout, N. Bayan, K. Park +4 more
2011Biochimica et Biophysica Acta45 citations Open access
Semantic Scholar
Molecular characterisation of the colicin E2 operon and identification of its products
S. Cole, B. Saint‐Joanis, A. Pugsley
2004Molecular and General Genetics MGG45 citations Open access
Semantic Scholar
Getting out: protein traffic in prokaryotes
A. Pugsley, O. Francetic, A. Driessen, V. de Lorenzo
2004Molecular Microbiology45 citations Open access
Semantic Scholar
Outer Membrane Targeting of Secretin PulD Protein Relies on Disordered Domain Recognition by a Dedicated Chaperone*♦
N. Nickerson, T. Tosi, A. Dessen, B. Baron +3 more
2011Journal of Biological Chemistry44 citations Open access
Semantic Scholar
Measure for measure in the control of type III secretion hook and needle length
T. Minamino, A. Pugsley
2005Molecular Microbiology42 citations
Semantic Scholar
The ChiA (YheB) protein of Escherichia coli K‐12 is an endochitinase whose gene is negatively controlled by the nucleoid‐structuring protein H‐NS
O. Francetic, C. Badaut, S. Rimsky, A. Pugsley
2000Molecular Microbiology42 citations Open access
Semantic Scholar
Pilotin–secretin recognition in the type II secretion system of Klebsiella oxytoca
T. Tosi, N. Nickerson, L. Mollica, M. R. Jensen +5 more
2011Molecular Microbiology40 citations
Semantic Scholar
Disulfide Bond Formation in Secreton Component PulK Provides a Possible Explanation for the Role of DsbA in Pullulanase Secretion
A. Pugsley, N. Bayan, N. Sauvonnet
2001Journal of Bacteriology40 citations Open access
Semantic Scholar
The role of the lipoprotein sorting signal (aspartate +2) in pullulanase secretion
I. Poquet, M. Kornacker, A. Pugsley
1993Molecular Microbiology39 citations
Semantic Scholar

Frequent co-authors

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I. Guilvout×12
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I. Guilvout — researcher profile on SciRah
O. Francetic×8
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O. Francetic — researcher profile on SciRah
M. Chami×7
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M. Chami — researcher profile on SciRah
N. Sauvonnet×6
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N. Sauvonnet — researcher profile on SciRah

×6

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N. Bayan — researcher profile on SciRah

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A. Engel — researcher profile on SciRah

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K. Hardie — researcher profile on SciRah

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O. Possot — researcher profile on SciRah

N. Nickerson×4

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N. Nickerson — researcher profile on SciRah

D. Vidal-Ingigliardi×3

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D. Vidal-Ingigliardi — researcher profile on SciRah

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P. Gounon — researcher profile on SciRah

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G. Vignon — researcher profile on SciRah