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A. Dessen · SciRah

Researcher profile · Semantic Scholar

A. Dessen

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A. Dessen — researcher profile on SciRah

h-index: 50
Works: 197
Citations: 10K

Most-cited papers

A Bacterial Protein Targets the BAHD1 Chromatin Complex to Stimulate Type III Interferon Response
A. Lebreton, G. Lakisic, V. Job, Lauriane Fritsch +11 more
2011Science182 citations
Semantic Scholar
Resistance to antibiotics targeted to the bacterial cell wall
I. Nikolaidis, S. Favini-Stabile, A. Dessen
2014Protein Science165 citations Open access
Semantic Scholar
Membrane targeting and pore formation by the type III secretion system translocon
P. Mattei, Éric Faudry, V. Job, T. Izoré +2 more
2011The FEBS Journal147 citations
Semantic Scholar
Structural Basis of Cytotoxicity Mediated by the Type III Secretion Toxin ExoU from Pseudomonas aeruginosa
Claire Gendrin, C. Contreras-Martel, S. Bouillot, S. Elsen +5 more
2012PLoS Pathogens77 citations Open access
Semantic Scholar
Molecular architecture of the PBP2–MreC core bacterial cell wall synthesis complex
C. Contreras-Martel, A. Martins, C. Ecobichon, D. Trindade +6 more
2017Nature Communications74 citations Open access
Semantic Scholar
FtsZ filament capping by MciZ, a developmental regulator of bacterial division
Alexandre W. Bisson-Filho, K. F. Discola, P. Castellen, Valdir Blasios +7 more
2015Proceedings of the National Academy of Sciences of the United States of America66 citations Open access
Semantic Scholar
Structure of a bacterial α2-macroglobulin reveals mimicry of eukaryotic innate immunity
S. Wong, A. Dessen
2014Nature Communications58 citations Open access
Semantic Scholar
An RNA-Binding Protein Secreted by a Bacterial Pathogen Modulates RIG-I Signaling
Alessandro Pagliuso, T. N. Tham, E. Allemand, Stevens Robertin +14 more
2019Cell Host and Microbe54 citations Open access
Semantic Scholar
Pore-forming activity of the Pseudomonas aeruginosa type III secretion system translocon alters the host epigenome
L. Dortet, C. Lombardi, F. Cretin, A. Dessen +1 more
2018Nature Microbiology54 citations
Semantic Scholar
Dual Inhibitor of MurD and MurE Ligases from Escherichia coli and Staphylococcus aureus.
T. Tomašič, R. Sink, Nace Zidar, Anja Fic +9 more
2012ACS Medicinal Chemistry Letters53 citations Open access
Semantic Scholar
Structure-guided design of cell wall biosynthesis inhibitors that overcome β-lactam resistance in Staphylococcus aureus (MRSA).
C. Contreras-Martel, A. Amoroso, E. Woon, A. Zervosen +9 more
2011ACS Chemical Biology50 citations
Semantic Scholar
Structure-based design of a new series of D-glutamic acid based inhibitors of bacterial UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase (MurD).
T. Tomašič, Nace Zidar, R. Sink, Andreja Kovač +8 more
2011Journal of Medicinal Chemistry49 citations
Semantic Scholar
MreB and MurG as scaffolds for the cytoplasmic steps of peptidoglycan biosynthesis.
S. Favini-Stabile, C. Contreras-Martel, N. Thielens, A. Dessen
2013Environmental Microbiology48 citations
Semantic Scholar
Penicillin-Binding Proteins (PBPs) and Bacterial Cell Wall Elongation Complexes.
Mayara M. Miyachiro, C. Contreras-Martel, A. Dessen
2019Sub-cellular biochemistry46 citations
Semantic Scholar
Structural Basis of Lipid Targeting and Destruction by the Type V Secretion System of Pseudomonas aeruginosa.
Paulo Vinicius da Mata Madeira, S. Zouhir, Pauline Basso, D. Neves +6 more
2016Journal of Molecular Biology45 citations
Semantic Scholar
Structure-activity relationships of new cyanothiophene inhibitors of the essential peptidoglycan biosynthesis enzyme MurF.
M. Hrast, Samo Turk, Izidor Sosič, D. Knez +8 more
2013European journal of medicinal chemistry45 citations Open access
Semantic Scholar
Outer Membrane Targeting of Secretin PulD Protein Relies on Disordered Domain Recognition by a Dedicated Chaperone*♦
N. Nickerson, T. Tosi, A. Dessen, B. Baron +3 more
2011Journal of Biological Chemistry44 citations Open access
Semantic Scholar
Structural and Functional Characterization of the Type Three Secretion System (T3SS) Needle of Pseudomonas aeruginosa
C. Lombardi, J. Tolchard, S. Bouillot, L. Signor +12 more
2019Frontiers in Microbiology43 citations Open access
Semantic Scholar
Specificity Determinants for Lysine Incorporation in Staphylococcus aureus Peptidoglycan as Revealed by the Structure of a MurE Enzyme Ternary Complex
K. Ruane, A. Lloyd, Vilmos Fülöp, C. Dowson +8 more
2013Journal of Biological Chemistry43 citations Open access
Semantic Scholar
Structural Basis for the Inhibition of the Chromatin Repressor BAHD1 by the Bacterial Nucleomodulin LntA
A. Lebreton, V. Job, M. Ragon, A. Le Monnier +3 more
2014mBio42 citations Open access
Semantic Scholar
Structural Basis of Pilus Anchoring by the Ancillary Pilin RrgC of Streptococcus pneumoniae*
M. Shaik, A. Maccagni, G. Tourcier, A. D. Di Guilmi +1 more
2014Journal of Biological Chemistry41 citations Open access
Semantic Scholar
The full-length Streptococcus pneumoniae major pilin RrgB crystallizes in a fibre-like structure, which presents the D1 isopeptide bond and provides details on the mechanism of pilus polymerization.
L. El Mortaji, C. Contreras-Martel, M. Moschioni, I. Ferlenghi +4 more
2012Biochemical Journal41 citations
Semantic Scholar
Pilotin–secretin recognition in the type II secretion system of Klebsiella oxytoca
T. Tosi, N. Nickerson, L. Mollica, M. R. Jensen +5 more
2011Molecular Microbiology40 citations
Semantic Scholar
Structural similarity of secretins from type II and type III secretion systems.
T. Tosi, L. F. Estrozi, V. Job, I. Guilvout +3 more
2014Structure38 citations Open access
Semantic Scholar
Penicillin-binding protein (PBP) inhibitor development: A 10-year chemical perspective
A. Bertonha, Caio C L Silva, Karina T. Shirakawa, D. Trindade +1 more
2023Experimental biology and medicine37 citations Open access
Semantic Scholar
Characterization of the elongasome core PBP2 : MreC complex of Helicobacter pylori
M. El Ghachi, P. Mattei, C. Ecobichon, A. Martins +9 more
2011Molecular Microbiology36 citations Open access
Semantic Scholar
Second-generation sulfonamide inhibitors of D-glutamic acid-adding enzyme: activity optimisation with conformationally rigid analogues of D-glutamic acid.
Izidor Sosič, H. Barreteau, M. Simčič, R. Sink +9 more
2011European journal of medicinal chemistry34 citations Open access
Semantic Scholar
Structural Insights into Protein-Protein Interactions Involved in Bacterial Cell Wall Biogenesis
F. Laddomada, Mayara M. Miyachiro, A. Dessen
2016Antibiotics32 citations Open access
Semantic Scholar
A boronic-acid-based probe for fluorescence polarization assays with penicillin binding proteins and β-lactamases.
S. Inglis, M. Strieker, A. M. Rydzik, A. Dessen +1 more
2012Analytical Biochemistry32 citations
Semantic Scholar
Calcium-Dependent Complex Formation Between PBP2 and Lytic Transglycosylase SltB1 of Pseudomonas aeruginosa
I. Nikolaidis, T. Izoré, V. Job, N. Thielens +2 more
2012Microbial Drug Resistance31 citations Open access
Semantic Scholar
Conformational States of a Bacterial α2-Macroglobulin Resemble Those of Human Complement C3
D. Neves, L. F. Estrozi, V. Job, F. Gabel +2 more
2012PLoS ONE30 citations Open access
Semantic Scholar
Unique Features of a Pseudomonas aeruginosa α2-Macroglobulin Homolog
Mylène Robert-Genthon, M. Casabona, D. Neves, Y. Couté +4 more
2013mBio29 citations Open access
Semantic Scholar
Membrane and Chaperone Recognition by the Major Translocator Protein PopB of the Type III Secretion System of Pseudomonas aeruginosa*
K. F. Discola, A. Förster, F. Boulay, J. Simorre +3 more
2013Journal of Biological Chemistry28 citations Open access
Semantic Scholar
Structural basis of eukaryotic cell targeting by type III secretion system (T3SS) effectors.
T. Tosi, A. Pflug, K. F. Discola, D. Neves +1 more
2013Research in Microbiology28 citations Open access
Semantic Scholar
Bacterial secretins: Mechanisms of assembly and membrane targeting
Yuri Rafael de Oliveira Silva, C. Contreras-Martel, P. Macheboeuf, A. Dessen
2020Protein Science26 citations Open access
Semantic Scholar
Crystallographic Study of Peptidoglycan Biosynthesis Enzyme MurD: Domain Movement Revisited
R. Sink, Miha Kotnik, A. Zega, H. Barreteau +4 more
2016PLoS ONE26 citations Open access
Semantic Scholar
Architecture and genomic arrangement of the MurE–MurF bacterial cell wall biosynthesis complex
Karina T. Shirakawa, F. A. Sala, Mayara M. Miyachiro, V. Job +2 more
2023Proceedings of the National Academy of Sciences of the United States of America25 citations Open access
Semantic Scholar
Self-association of MreC as a regulatory signal in bacterial cell wall elongation
A. Martins, C. Contreras-Martel, Manon Janet-Maitre, Mayara M. Miyachiro +9 more
2021Nature Communications22 citations Open access
Semantic Scholar
Structure and assembly of pilotin-dependent and -independent secretins of the type II secretion system
S. Howard, L. F. Estrozi, Q. Bertrand, C. Contreras-Martel +6 more
2019PLoS Pathogens22 citations Open access
Semantic Scholar
A Structural Snapshot of Type II Pilus Formation in Streptococcus pneumoniae*
M. Shaik, C. Lombardi, Daniel Maragno Trindade, D. Fenel +3 more
2015Journal of Biological Chemistry22 citations Open access
Semantic Scholar
Structure of internalin InlK from the human pathogen Listeria monocytogenes.
D. Neves, V. Job, L. Dortet, P. Cossart +1 more
2013Journal of Molecular Biology22 citations
Semantic Scholar
The MurG glycosyltransferase provides an oligomeric scaffold for the cytoplasmic steps of peptidoglycan biosynthesis in the human pathogen Bordetella pertussis
F. Laddomada, Mayara M. Miyachiro, M. Jessop, D. Patin +7 more
2019Scientific Reports18 citations Open access
Semantic Scholar
Combined Structural Analysis and Molecular Dynamics Reveal Penicillin-Binding Protein Inhibition Mode with β-Lactones
Parker L Flanders, C. Contreras-Martel, Nathaniel W. Brown, Joshua D. Shirley +5 more
2022ACS Chemical Biology15 citations Open access
Semantic Scholar
Complex formation between Mur enzymes from Streptococcus pneumoniae.
Mayara M. Miyachiro, D. Granato, D. Trindade, C. Ebel +2 more
2019Biochemistry15 citations
Semantic Scholar
Chemical Elicitors Induce Rare Bioactive Secondary Metabolites in Deep-Sea Bacteria under Laboratory Conditions
R. de Felício, P. Ballone, C. Bazzano, Luiz F. G. Alves +14 more
2021Metabolites14 citations Open access
Semantic Scholar
Exolysin (ExlA) from Pseudomonas aeruginosa Punctures Holes into Target Membranes Using a Molten Globule Domain.
Q. Bertrand, V. Job, A. Maillard, L. Imbert +6 more
2020Journal of Molecular Biology14 citations Open access
Semantic Scholar
The inherent flexibility of type I non-ribosomal peptide synthetase multienzymes drives their catalytic activities
Sarah Bonhomme, A. Dessen, P. Macheboeuf
2021Open Biology10 citations Open access
Semantic Scholar
Monitoring Drug-Protein Interactions in the Bacterial Periplasm by Solution Nuclear Magnetic Resonance Spectroscopy.
Alicja Razew, Quentin Herail, Mayara M. Miyachiro, Constantin Anoyatis-Pelé +4 more
2024Journal of the American Chemical Society9 citations Open access
Semantic Scholar
Architecture of a PKS-NRPS hybrid megaenzyme involved in the biosynthesis of the genotoxin colibactin.
Sarah Bonhomme, C. Contreras-Martel, A. Dessen, P. Macheboeuf
2023Structure9 citations Open access
Semantic Scholar
Draft genome sequence of Psychrobacter nivimaris LAMA 639 and its biotechnological potential
Brendon Egon Kormann Staloch, Henrique Niero, Robert Cardoso de Freitas, P. Ballone +5 more
2022Data in Brief9 citations Open access
Semantic Scholar

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