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J. Ridinger · SciRah

Researcher profile · Semantic Scholar

J. Ridinger

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J. Ridinger — researcher profile on SciRah

h-index: 18
Works: 34
Citations: 1,668

Most-cited papers

Body fluid derived exosomes as a novel template for clinical diagnostics
Sascha Keller, J. Ridinger, Anne-Kathleen Rupp, Johannes W. G. Janssen +1 more
2011Journal of Translational Medicine704 citations Open access
Semantic Scholar
Body Fluid Exosomes Promote Secretion of Inflammatory Cytokines in Monocytic Cells via Toll-like Receptor Signaling*
Niko P. Bretz, J. Ridinger, Anne-Kathleen Rupp, Katharina Rimbach +8 more
2013Journal of Biological Chemistry230 citations Open access
Semantic Scholar
L1CAM
H. Kiefel, Sandra Bondong, John Hazin, J. Ridinger +3 more
2012Cell Adhesion & Migration116 citations Open access
Semantic Scholar
Selective Inhibition of Histone Deacetylase 10: Hydrogen Bonding to the Gatekeeper Residue is Implicated.
Magalie N E Géraldy, M. Morgen, P. Sehr, Raphael R. Steimbach +9 more
2018Journal of Medicinal Chemistry74 citations Open access
Semantic Scholar
Novel insights into exosome-induced, tumor-associated inflammation and immunomodulation.
P. Altevogt, Niko P. Bretz, J. Ridinger, J. Utikal +1 more
2014Seminars in Cancer Biology69 citations
Semantic Scholar
Three-dimensional tumor cell growth stimulates autophagic flux and recapitulates chemotherapy resistance
C. Bingel, E. Koeneke, J. Ridinger, A. Bittmann +10 more
2017Cell Death and Disease53 citations Open access
Semantic Scholar
Dual role of HDAC10 in lysosomal exocytosis and DNA repair promotes neuroblastoma chemoresistance
J. Ridinger, E. Koeneke, Fiona R. Kolbinger, Katharina Koerholz +9 more
2018Scientific Reports47 citations Open access
Semantic Scholar
Establishment and application of a novel patient-derived KIAA1549:BRAF-driven pediatric pilocytic astrocytoma model for preclinical drug testing
F. Selt, J. Hohloch, T. Hielscher, F. Sahm +20 more
2016OncoTarget45 citations Open access
Semantic Scholar
Design, Synthesis and Biological Characterization of Histone Deacetylase 8 (HDAC8) Proteolysis Targeting Chimeras (PROTACs) with Anti-Neuroblastoma Activity
S. Darwish, Ehab Ghazy, Tino Heimburg, Daniel Herp +11 more
2022International Journal of Molecular Sciences35 citations Open access
Semantic Scholar
Reduced chromatin binding of MYC is a key effect of HDAC inhibition in MYC amplified medulloblastoma.
J. Ecker, Venu Thatikonda, Gianluca Sigismondo, F. Selt +20 more
2020Neuro-Oncology34 citations Open access
Semantic Scholar
Aza-SAHA Derivatives are Selective Histone Deacetylase 10 Chemical Probes That Inhibit Polyamine Deacetylation and Phenocopy HDAC10 Knockout
Raphael R. Steimbach, C. J. Herbst‐Gervasoni, Severin Lechner, T. M. Stewart +14 more
2022Journal of the American Chemical Society31 citations Open access
Semantic Scholar
The HDAC6/8/10 inhibitor TH34 induces DNA damage-mediated cell death in human high-grade neuroblastoma cell lines
Fiona R. Kolbinger, E. Koeneke, J. Ridinger, Tino Heimburg +9 more
2018Archives of Toxicology30 citations Open access
Semantic Scholar
Functional Therapeutic Target Validation Using Pediatric Zebrafish Xenograft Models
Charlotte Gatzweiler, J. Ridinger, Sonja Herter, Xenia F. Gerloff +23 more
2022Cancers29 citations Open access
Semantic Scholar
Broad-Spectrum HDAC Inhibitors Promote Autophagy through FOXO Transcription Factors in Neuroblastoma
Katharina Körholz, J. Ridinger, D. Krunic, S. Najafi +7 more
2021Cells27 citations Open access
Semantic Scholar
Rapid In Vivo Validation of HDAC Inhibitor-Based Treatments in Neuroblastoma Zebrafish Xenografts
Jagoda K. Wrobel, S. Najafi, Simay Ayhan, Charlotte Gatzweiler +9 more
2020Pharmaceuticals27 citations Open access
Semantic Scholar
Design and Synthesis of Dihydroxamic Acids as HDAC6/8/10 Inhibitors
A. Miller, M. Morgen, Raphael R. Steimbach, Magalie N E Géraldy +10 more
2020ChemMedChem25 citations Open access
Semantic Scholar
Identification of Histone Deacetylase 10 (HDAC10) Inhibitors that Modulate Autophagy in Transformed Cells
P. Zeyen, Yanira Zeyn, Daniel Herp, F. Mahmoudi +12 more
2022European journal of medicinal chemistry24 citations Open access
Semantic Scholar
First fluorescent acetylspermidine deacetylation assay for HDAC10 identifies selective inhibitors with cellular target engagement
Daniel Herp, J. Ridinger, D. Robaa, Stephen A. Shinsky +14 more
2022ChemBioChem19 citations Open access
Semantic Scholar
Combining APR-246 and HDAC-Inhibitors: A Novel Targeted Treatment Option for Neuroblastoma
Michael Müller, Lisa Rösch, S. Najafi, Charlotte Gatzweiler +13 more
2021Cancers12 citations Open access
Semantic Scholar
Class I HDAC inhibitor entinostat synergizes with PLK1 inhibitors in MYC-amplified medulloblastoma cells
G. Valinciute, J. Ecker, F. Selt, T. Hielscher +21 more
2023Journal of Neuro-Oncology9 citations Open access
Semantic Scholar
ERBB and P‐glycoprotein inhibitors break resistance in relapsed neuroblastoma models through P‐glycoprotein
Lisa Rösch, Sonja Herter, S. Najafi, J. Ridinger +6 more
2022Molecular Oncology8 citations Open access
Semantic Scholar
Aza-SAHA Derivatives are Selective Histone Deacetylase 10 Chemical Probes That Inhibit Polyamine Deacetylation
Raphael R. Steimbach, C. J. Herbst‐Gervasoni, Glynis Klinke, Magalie N E Géraldy +7 more
20216 citations Open access
Semantic Scholar
Class I HDAC inhibition reduces DNA damage repair capacity of MYC-amplified medulloblastoma cells
J. Vollmer, J. Ecker, T. Hielscher, G. Valinciute +7 more
2023Journal of Neuro-Oncology4 citations Open access
Semantic Scholar
Synthesis, Biochemical, and Cellular Evaluation of HDAC6 Targeting Proteolysis Targeting Chimeras.
S. Darwish, Tino Heimburg, J. Ridinger, Daniel Herp +5 more
2023Methods in molecular biology4 citations
Semantic Scholar
Evaluation of Antitumor and On-Target Activity of HDAC Inhibitors with the Zebrafish Embryo Xenograft Model.
Charlotte Gatzweiler, J. Ridinger, Simay Ayhan, S. Najafi +3 more
2023Methods in molecular biology3 citations
Semantic Scholar
First Fluorescent Acetylspermidine Deacetylation Assay for HDAC10 Identifies Inhibitors of Neuroblastoma Cell Colony Growth That Increase Lysosome Accumulation
Daniel Herp, J. Ridinger, D. Robaa, Stephen A. Shinsky +10 more
20203 citations Open access
Semantic Scholar
RAGE ligand S100A8/A9 as a novel prognostic biomarker for high-risk melanoma patients.
C. Gebhardt, N. Wagner, B. Weide, R. Lichtenberger +12 more
20141 citations
Semantic Scholar
Identification of HDAC10 Inhibitors that Modulate Autophagy-Related Proteins in Transformed Cells
P. Zeyen, Yanira Zeyn, Daniel Herp, F. Mahmoudi +11 more
20220 citations Open access
Semantic Scholar
EMBR-01. CLASS I HDAC INHIBITORS AND PLK1 INHIBITORS SYNERGIZE IN MYC-AMPLIFIED MEDULLOBLASTOMA
G. Valinciute, J. Ecker, F. Selt, T. Hielscher +14 more
2021Neuro-Oncology0 citations Open access
Semantic Scholar
HDAC10 in neuroblastoma chemoresistance
J. Ridinger
20190 citations
Semantic Scholar
LGG-11. REGULATION OF ONCOGENE-INDUCED SENESCENCE IN PILOCYTIC ASTROCYTOMA
J. Buhl, F. Selt, T. Hielscher, F. Sahm +16 more
2018Neuro-Oncology0 citations Open access
Semantic Scholar
Three-dimensional tumor cell growth models in vivo drug resistance mechanisms
C. Bingel, E. Koeneke, A. Bittmann, M. Sill +7 more
20160 citations
Semantic Scholar
Methods to unravel the role of HDAC10 in autophagy-related drug resistance
J. Fabian, J. Ridinger, O. Witt, I. Oehme
20150 citations
Semantic Scholar
, Johannes Ridinger , via Toll-like Receptor Signaling CellsInflammatory Cytokines in Monocytic Body Fluid Exosomes Promote Secretion of Signal Transduction
Niko P. Bretz, J. Ridinger, Anne-Kathleen Rupp, Katharina Rimbach +8 more
20130 citations
Semantic Scholar

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