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Raphael R. Steimbach · SciRah

Researcher profile · Semantic Scholar

Raphael R. Steimbach

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Raphael R. Steimbach — researcher profile on SciRah

h-index: 13
Works: 22
Citations: 469

Most-cited papers

Target deconvolution of HDAC pharmacopoeia reveals MBLAC2 as common off-target
Severin Lechner, M. Malgapo, C. Grätz, Raphael R. Steimbach +21 more
2022Nature Chemical Biology108 citations Open access
Semantic Scholar
Selective Inhibition of Histone Deacetylase 10: Hydrogen Bonding to the Gatekeeper Residue is Implicated.
Magalie N E Géraldy, M. Morgen, P. Sehr, Raphael R. Steimbach +9 more
2018Journal of Medicinal Chemistry74 citations Open access
Semantic Scholar
Novel 2, 5-diketopiperazine derivatives as potent selective histone deacetylase 6 inhibitors: Rational design, synthesis and antiproliferative activity.
Xin Chen, Xin-Yan Chen, Raphael R. Steimbach, Tong Wu +9 more
2019European journal of medicinal chemistry33 citations Open access
Semantic Scholar
Aza-SAHA Derivatives are Selective Histone Deacetylase 10 Chemical Probes That Inhibit Polyamine Deacetylation and Phenocopy HDAC10 Knockout
Raphael R. Steimbach, C. J. Herbst‐Gervasoni, Severin Lechner, T. M. Stewart +14 more
2022Journal of the American Chemical Society31 citations Open access
Semantic Scholar
Frontispiz: Commonly Used Alkylating Agents Limit Persulfide Detection by Converting Protein Persulfides into Thioethers
Danny Schilling, U. Barayeu, Raphael R. Steimbach, D. Talwar +2 more
2022Angewandte Chemie29 citations
Semantic Scholar
Structural Basis for the Selective Inhibition of HDAC10, the Cytosolic Polyamine Deacetylase
C. J. Herbst‐Gervasoni, Raphael R. Steimbach, M. Morgen, A. Miller +1 more
2020ACS Chemical Biology29 citations Open access
Semantic Scholar
Design and Synthesis of Dihydroxamic Acids as HDAC6/8/10 Inhibitors
A. Miller, M. Morgen, Raphael R. Steimbach, Magalie N E Géraldy +10 more
2020ChemMedChem25 citations Open access
Semantic Scholar
Chemoproteomic target deconvolution reveals Histone Deacetylases as targets of (R)-lipoic acid
Severin Lechner, Raphael R. Steimbach, Long-Long Wang, Marshall L. Deline +7 more
2023Nature Communications23 citations Open access
Semantic Scholar
First fluorescent acetylspermidine deacetylation assay for HDAC10 identifies selective inhibitors with cellular target engagement
Daniel Herp, J. Ridinger, D. Robaa, Stephen A. Shinsky +14 more
2022ChemBioChem19 citations Open access
Semantic Scholar
Decrypting lysine deacetylase inhibitor action and protein modifications by dose-resolved proteomics.
Yun-Chien Chang, Christian Gnann, Raphael R. Steimbach, Florian P. Bayer +9 more
2024Cell Reports17 citations Open access
Semantic Scholar
Tetrahydro-β-carboline derivatives as potent histone deacetylase 6 inhibitors with broad-spectrum antiproliferative activity.
Xin Chen, Jiayun Wang, Peng Zhao, Baiyun Dang +9 more
2023European journal of medicinal chemistry17 citations Open access
Semantic Scholar
Histone deacetylase-10 liberates spermidine to support polyamine homeostasis and tumor cell growth
T. M. Stewart, J. Foley, Cassandra E. Holbert, Glynis Klinke +4 more
2022Journal of Biological Chemistry17 citations Open access
Semantic Scholar
Site-specific activation of the proton pump inhibitor rabeprazole by tetrathiolate zinc centres
Teresa Marker, Raphael R. Steimbach, Cecilia Perez-Borrajero, Marcin Luzarowski +10 more
2025Nature Chemistry16 citations Open access
Semantic Scholar
Commonly Used Alkylating Agents Limit Persulfide Detection by Converting Protein Persulfides into Thioethers
Danny Schilling, U. Barayeu, Raphael R. Steimbach, D. Talwar +2 more
2022Angewandte Chemie13 citations Open access
Semantic Scholar
Aza-SAHA Derivatives are Selective Histone Deacetylase 10 Chemical Probes That Inhibit Polyamine Deacetylation
Raphael R. Steimbach, C. J. Herbst‐Gervasoni, Glynis Klinke, Magalie N E Géraldy +7 more
20216 citations Open access
Semantic Scholar
Can an Intermediate Rate of Nitrogen Inversion Affect Drug Efficacy?
Raphael R. Steimbach, Gergely Tihanyi, Magalie N E Géraldy, Alicja Wzorek +2 more
2021Symmetry5 citations Open access
Semantic Scholar
Direct Imaging of Protein‐Specific Methylation in Mammalian Cells
Franziska Doll, Raphael R. Steimbach, A. Zumbusch
2019ChemBioChem5 citations
Semantic Scholar
TR-FRET assay for profiling HDAC10 inhibitors and PROTACs.
K. Remans, Peter Sehr, Raphael R. Steimbach, N. Gunkel +1 more
2025Methods in Enzymology1 citations
Semantic Scholar
Author Correction: Target deconvolution of HDAC pharmacopoeia reveals MBLAC2 as common off-target
Severin Lechner, M. Malgapo, C. Grätz, Raphael R. Steimbach +21 more
2022Nature Chemical Biology1 citations Open access
Semantic Scholar
Site-specific activation of proton pump inhibitors by C4-type zinc fingers
Teresa Marker, Raphael R. Steimbach, Cecilia Perez-Borrajero, Marcin Luzarowski +5 more
2024Free Radical Biology & Medicine0 citations
Semantic Scholar
Abstract LB210: Identification of histone deacetylase 10 as a repressor of cancer cell migration
Ting-Ann Liu, Ashley C. Nwafor, Rajendra Kumar, L. Sena +4 more
2024Cancer Research0 citations
Semantic Scholar
Abstract 5812: Histone deacetylase 10 supports tumor growth under polyamine-limiting conditions
T. M. Stewart, Raphael R. Steimbach, J. Foley, A. Miller +1 more
2022Cancer Research0 citations
Semantic Scholar

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