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C. Brocker · SciRah

Researcher profile · Semantic Scholar

C. Brocker

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C. Brocker — researcher profile on SciRah

h-index: 35
Works: 61
Citations: 6,644

Most-cited papers

Intermittent Fasting Promotes White Adipose Browning and Decreases Obesity by Shaping the Gut Microbiota
Guo-Lin Li, Cen Xie, Si-Yu Lu, Robert G. Nichols +11 more
2017Cell Metabolism631 citations Open access
Semantic Scholar
Non-P450 aldehyde oxidizing enzymes: the aldehyde dehydrogenase superfamily
S. Marchitti, C. Brocker, D. Stagos, V. Vasiliou
2008Expert Opinion on Drug Metabolism & Toxicology616 citations Open access
Semantic Scholar
Aldehyde Dehydrogenases in Cellular Responses to Oxidative/electrophilic Stress
Surendra Singh, C. Brocker, Vindhya Koppaka, Che-Na Ying +4 more
2012Free Radical Biology & Medicine601 citations Open access
Semantic Scholar
Intestine-selective farnesoid X receptor inhibition improves obesity-related metabolic dysfunction
Chang-Tao Jiang, Cen Xie, Ying Lv, Jing Li +10 more
2015Nature Communications531 citations Open access
Semantic Scholar
Evolutionary divergence and functions of the human interleukin (IL) gene family
C. Brocker, David C. Thompson, Akiko Matsumoto, D. Nebert +1 more
2010Human Genomics368 citations Open access
Semantic Scholar
Dietary intake regulates the circulating inflammatory monocyte pool
Stefan Jordan, Navpreet Tung, M. Casanova-Acebes, Christie Chang +23 more
2019bioRxiv363 citations Open access
Semantic Scholar
Update on the aldehyde dehydrogenase gene (ALDH) superfamily
Brian C. Jackson, C. Brocker, David C. Thompson, W. Black +3 more
2011Human Genomics344 citations Open access
Semantic Scholar
The role of hyperosmotic stress in inflammation and disease
C. Brocker, David C. Thompson, V. Vasiliou
2012Biomolecular Concepts287 citations Open access
Semantic Scholar
Cyp2c70 is responsible for the species difference in bile acid metabolism between mice and humans[S]
Shogo Takahashi, T. Fukami, Yusuke Masuo, C. Brocker +5 more
2016Journal of Lipid Research270 citations Open access
Semantic Scholar
Non-P 450 aldehyde oxidizing enzymes : the aldehyde dehydrogenase superfamily
S. Marchitti, C. Brocker, D. Stagos, V. Vasiliou
2009232 citations
Semantic Scholar
Aldehyde Dehydrogenase 7A1 (ALDH7A1) Is a Novel Enzyme Involved in Cellular Defense against Hyperosmotic Stress*
C. Brocker, N. Lassen, Tia Estey, Aglaia Pappa +6 more
2010Journal of Biological Chemistry195 citations Open access
Semantic Scholar
Aldehyde dehydrogenase (ALDH) superfamily in plants: gene nomenclature and comparative genomics
C. Brocker, Melpomene Vasiliou, S. Carpenter, Christopher Carpenter +8 more
2012Planta163 citations Open access
Semantic Scholar
Intestinal PPARα Protects Against Colon Carcinogenesis via Regulation of Methyltransferases DNMT1 and PRMT6
Yuhong Luo, Cen Xie, C. Brocker, Jie Fan +10 more
2019Gastroenterology145 citations Open access
Semantic Scholar
Aldehyde Dehydrogenase 1B1: Molecular Cloning and Characterization of a Novel Mitochondrial Acetaldehyde-Metabolizing Enzyme
D. Stagos, Ying Chen, C. Brocker, E. Donald +4 more
2010Drug Metabolism And Disposition140 citations Open access
Semantic Scholar
Genome-Wide Identification and Analysis of Grape Aldehyde Dehydrogenase (ALDH) Gene Superfamily
Yu-Cheng Zhang, L. Mao, Hua Wang, C. Brocker +4 more
2012PLoS ONE110 citations Open access
Semantic Scholar
UAP56 levels affect viability and mRNA export in Caenorhabditis elegans.
M. MacMorris, C. Brocker, T. Blumenthal
2003RNA: A publication of the RNA Society98 citations Open access
Semantic Scholar
Evolutionary divergence and functions of the ADAM and ADAMTS gene families
C. Brocker, V. Vasiliou, D. Nebert
2009Human Genomics96 citations Open access
Semantic Scholar
Aldehyde dehydrogenase 7A1 (ALDH7A1) attenuates reactive aldehyde and oxidative stress induced cytotoxicity
C. Brocker, M. Cantore, P. Failli, V. Vasiliou
2011Chemico-Biological Interactions95 citations Open access
Semantic Scholar
Evolutionary divergence and functions of the human acyl-CoA thioesterase gene (ACOT) family
C. Brocker, Christopher Carpenter, D. Nebert, V. Vasiliou
2010Human Genomics92 citations Open access
Semantic Scholar
Hepatocyte-specific PPARA expression exclusively promotes agonist-induced cell proliferation without influence from nonparenchymal cells.
C. Brocker, J. Yue, Donghwan Kim, Ai-Juan Qu +2 more
2017American Journal of Physiology - Gastrointestinal and Liver Physiology87 citations Open access
Semantic Scholar
The genotypic and phenotypic spectrum of pyridoxine-dependent epilepsy due to mutations in ALDH7A1
G. Scharer, C. Brocker, V. Vasiliou, Geralyn Creadon-Swindell +3 more
2010Journal of Inherited Metabolic Disease86 citations Open access
Semantic Scholar
Intermittent Fasting Promotes White Adipose Browning and Decreases Obesity by Shaping the Gut Microbiota
Guo-Lin Li, Cen Xie, Siyu Lu, Robert G. Nichols +11 more
2017Cell Metabolism74 citations Open access
Semantic Scholar
REVERBa couples the circadian clock to hepatic glucocorticoid action
G. Caratti, M. Iqbal, L. Hunter, Donghwan Kim +22 more
2018Journal of Clinical Investigation72 citations Open access
Semantic Scholar
Long non-coding RNA Gm15441 attenuates hepatic inflammasome activation in response to PPARA agonism and fasting
C. Brocker, Donghwan Kim, T. Melia, Kritika Karri +7 more
2020Nature Communications70 citations Open access
Semantic Scholar
Extrahepatic PPARα modulates fatty acid oxidation and attenuates fasting-induced hepatosteatosis in mice[S]
C. Brocker, Daxesh P. Patel, T. Velenosi, Donghwan Kim +5 more
2018Journal of Lipid Research70 citations Open access
Semantic Scholar
Glycyrrhizin Protects against Acetaminophen-Induced Acute Liver Injury via Alleviating Tumor Necrosis Factor α–Mediated Apoptosis
Tingting Yan, Hong Wang, Min Zhao, T. Yagai +12 more
2016Drug Metabolism And Disposition68 citations Open access
Semantic Scholar
Molecular Characterization, Expression Analysis and Role of ALDH3B1 in The Cellular Protection Against Oxidative Stress
S. Marchitti, C. Brocker, D. Orlicky, V. Vasiliou
2010Free Radical Biology & Medicine67 citations Open access
Semantic Scholar
Epigenetic control of EMT/MET dynamics: HNF4α impacts DNMT3s through miRs-29,
Carla Cicchini, Valeria de Nonno, Cecilia Battistelli, A. M. Cozzolino +6 more
2015Biochimica et Biophysica Acta64 citations Open access
Semantic Scholar
Hepatocyte peroxisome proliferator-activated receptor α regulates bile acid synthesis and transport
Cen Xie, Shogo Takahashi, C. Brocker, Shi-Jun He +8 more
2019Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids58 citations Open access
Semantic Scholar
Gemfibrozil disrupts lysophosphatidylcholine and bile acid homeostasis via PPARα and its relevance to hepatotoxicity
Ai-Ming Liu, K. Krausz, Zhong-Ze Fang, C. Brocker +2 more
2014Archives of Toxicology48 citations Open access
Semantic Scholar
PPARα-dependent exacerbation of experimental colitis by the hypolipidemic drug fenofibrate.
Yun-Peng Qi, Chang-Tao Jiang, N. Tanaka, K. Krausz +5 more
2014American Journal of Physiology - Gastrointestinal and Liver Physiology44 citations Open access
Semantic Scholar
Aldehyde dehydrogenases are regulators of hematopoietic stem cell numbers and B-cell development.
M. Gasparetto, Sanja Sekulovic, C. Brocker, P. Tang +14 more
2012Experimental Hematology42 citations Open access
Semantic Scholar
Aldehyde dehydrogenase 3B1 (ALDH3B1): immunohistochemical tissue distribution and cellular-specific localization in normal and cancerous human tissues.
S. Marchitti, D. Orlicky, C. Brocker, V. Vasiliou
2010Journal of Histochemistry and Cytochemistry40 citations Open access
Semantic Scholar
Keratin 23 is a PPARA-dependent, MYC-amplified oncogene that promotes hepatocyte proliferation
Donghwan Kim, C. Brocker, Shogo Takahashi, T. Yagai +5 more
2019Hepatology39 citations Open access
Semantic Scholar
Gene repression through epigenetic modulation by PPARA enhances hepatocellular proliferation
Daisuke Aibara, Shogo Takahashi, T. Yagai, Donghwan Kim +4 more
2022iScience35 citations Open access
Semantic Scholar
Metabolomic profiling of metoprolol hypertension treatment reveals altered gut microbiota-derived urinary metabolites
C. Brocker, T. Velenosi, Hanna K. Flaten, G. McWilliams +6 more
2020Human Genomics33 citations Open access
Semantic Scholar
Aldehyde Dehydrogenase 3B1 (ALDH3B1): Immunohistochemical Tissue Distribution and Cellular-specific Localization in Normal and Cancerous Human Tissues
S. Marchitti, D. Orlicky, C. Brocker, V. Vasiliou
201032 citations Open access
Semantic Scholar
Metabolic adaptation to intermittent fasting is independent of peroxisome proliferator-activated receptor alpha
Guo-Lin Li, C. Brocker, Tingting Yan, Cen Xie +3 more
2017Molecular Metabolism29 citations Open access
Semantic Scholar
Improved drug therapy: triangulating phenomics with genomics and metabolomics
Andrew A. Monte, C. Brocker, D. Nebert, F. Gonzalez +2 more
2014Human Genomics29 citations Open access
Semantic Scholar
Cyp 2 c 70 is responsible for the species difference in bile acid metabolism between mice and humans
Shogo Takahashi, T. Fukami, Yusuke Masuo, C. Brocker +5 more
201628 citations
Semantic Scholar
Diabetes-linked transcription factor HNF4α regulates metabolism of endogenous methylarginines and β-aminoisobutyric acid by controlling expression of alanine-glyoxylate aminotransferase 2
D. V. Burdin, A. Kolobov, C. Brocker, A. Soshnev +12 more
2016Scientific Reports24 citations Open access
Semantic Scholar
aldh7a1 Regulates Eye and Limb Development in Zebrafish
Holly E. Babcock, S. Dutta, Ramakrishna P. Alur, C. Brocker +4 more
2014PLoS ONE24 citations Open access
Semantic Scholar
Hepatic peroxisome proliferator-activated receptor alpha mediates the major metabolic effects of Wy-14643
Guo-Lin Li, C. Brocker, Cen Xie, Tingting Yan +4 more
2017Journal of Gastroenterology and Hepatology22 citations Open access
Semantic Scholar
Hepatocyte Peroxisome Proliferator-Activated Receptor α Enhances Liver Regeneration after Partial Hepatectomy in Mice.
Guo-Min Xie, Shi Yin, Zhenzhen Zhang, Dan Qi +8 more
2019American Journal of Pathology20 citations Open access
Semantic Scholar
Hepatocyte Peroxisome Proliferator e Activated Receptor a Enhances Liver Regeneration after Partial Hepatectomy in Mice
Guo-Min Xie, S. Yin, Zhenzhen Zhang, Dan Qi +8 more
201918 citations
Semantic Scholar
Feedback repression of PPARα signaling by Let-7 microRNA
T. Yagai, Tingting Yan, Yuhong Luo, Shogo Takahashi +6 more
2021Cell Reports15 citations Open access
Semantic Scholar
Long non-coding RNA G23Rik attenuates fasting-induced lipid accumulation in mouse liver
Donghwan Kim, Bora Kim, C. Brocker, Kritika Karri +2 more
2022Molecular and Cellular Endocrinology8 citations Open access
Semantic Scholar
Hepatic sirtuin 1 is dispensable for fibrate-induced peroxisome proliferator-activated receptor-α function in vivo.
J. Bonzo, C. Brocker, Chang-Tao Jiang, Rui-Hong Wang +2 more
2014American Journal of Physiology. Endocrinology and Metabolism8 citations Open access
Semantic Scholar
Manipulation of cellular GSH biosynthetic capacity via TAT-mediated protein transduction of wild-type or a dominant-negative mutant of glutamate cysteine ligase alters cell sensitivity to oxidant-induced cytotoxicity
Donald S. Backos, C. Brocker, C. C. Franklin
2009Toxicology and Applied Pharmacology5 citations Open access
Semantic Scholar
Corrigendum to "Metabolic adaptation to intermittent fasting is independent of peroxisome proliferator-activated receptor alpha" [Mol Metab 7 (2018) 80-89].
Guo-Lin Li, C. Brocker, Tingting Yan, Cen Xie +3 more
2018Molecular Metabolism4 citations Open access
Semantic Scholar

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