Researcher profile · Semantic Scholar

Robert G. Nichols

h-index: 23
Works: 34
Citations: 4,456

Most-cited papers

Gut microbiota and intestinal FXR mediate the clinical benefits of metformin
Lu-Lu Sun, Cen Xie, Guang Wang, Yuehua Wu +24 more
2018Nature Medicine898 citations Open access
Semantic Scholar
Intermittent Fasting Promotes White Adipose Browning and Decreases Obesity by Shaping the Gut Microbiota
Guo-Lin Li, Cen Xie, Si-Yu Lu, Robert G. Nichols +11 more
2017Cell Metabolism631 citations Open access
Semantic Scholar
Intestinal farnesoid X receptor signaling promotes nonalcoholic fatty liver disease.
Chang-Tao Jiang, Cen Xie, Fei Li, Li-Min Zhang +12 more
2015Journal of Clinical Investigation620 citations Open access
Semantic Scholar
Intestine farnesoid X receptor agonist and the gut microbiota activate G-protein bile acid receptor-1 signaling to improve metabolism
P. Pathak, Cen Xie, Robert G. Nichols, Jessica M. Ferrell +5 more
2018Hepatology521 citations Open access
Semantic Scholar
Supplemental Material Persistent Organic Pollutants Modify Gut Microbiota – Host Metabolic Homeostasis in Mice Through Aryl Hydrocarbon Receptor Activation
Li-Min Zhang, Robert G. Nichols, Jared B. Correll, I. Murray +9 more
2015272 citations
Semantic Scholar
The microbiome modulating activity of bile acids
Yuan Tian, Wei Gui, Imhoi Koo, Philip B. W. Smith +6 more
2020Gut microbes238 citations Open access
Semantic Scholar
The relationship between the gut microbiome and host gene expression: a review
Robert G. Nichols, Emily R. Davenport
2020Human Genetics139 citations Open access
Semantic Scholar
Bile salt hydrolase in non-enterotoxigenic Bacteroides potentiates colorectal cancer
Lu-Lu Sun, Y. Zhang, Jiong Cai, Bipin Rimal +13 more
2023Nature Communications130 citations Open access
Semantic Scholar
Farnesoid X Receptor Signaling Shapes the Gut Microbiota and Controls Hepatic Lipid Metabolism
Li-Min Zhang, Cen Xie, Robert G. Nichols, S. H. Chan +9 more
2016mSystems105 citations Open access
Semantic Scholar
Berberine Directly Affects the Gut Microbiota to Promote Intestinal Farnesoid X Receptor Activation
Yuan Tian, Jingwei Cai, Wei Gui, Robert G. Nichols +4 more
2018Drug Metabolism And Disposition95 citations Open access
Semantic Scholar
Metabolomics Reveals that Aryl Hydrocarbon Receptor Activation by Environmental Chemicals Induces Systemic Metabolic Dysfunction in Mice
Li-Min Zhang, E. Hatzakis, Robert G. Nichols, Ruixin Hao +5 more
2015Environmental Science and Technology80 citations Open access
Semantic Scholar
Dietary Broccoli Impacts Microbial Community Structure and Attenuates Chemically Induced Colitis in Mice in an Ah receptor dependent manner
T. Hubbard, I. Murray, Robert G. Nichols, K. Cassel +7 more
2017Journal of Functional Foods76 citations Open access
Semantic Scholar
Intermittent Fasting Promotes White Adipose Browning and Decreases Obesity by Shaping the Gut Microbiota
Guo-Lin Li, Cen Xie, Siyu Lu, Robert G. Nichols +11 more
2017Cell Metabolism74 citations Open access
Semantic Scholar
Expression of the aryl hydrocarbon receptor contributes to the establishment of intestinal microbial community structure in mice
I. Murray, Robert G. Nichols, Li-Min Zhang, Andrew D. Patterson +1 more
2016Scientific Reports72 citations Open access
Semantic Scholar
Perfluorooctane Sulfonate Alters Gut Microbiota-Host Metabolic Homeostasis in Mice
Li-Min Zhang, Bipin Rimal, Robert G. Nichols, Yuan Tian +6 more
2020Toxicology71 citations Open access
Semantic Scholar
Vitamin A deficiency in mice alters host and gut microbial metabolism leading to altered energy homeostasis
Yuan Tian, Robert G. Nichols, Jingwei Cai, Andrew D. Patterson +1 more
2017Journal of Nutritional Biochemistry68 citations Open access
Semantic Scholar
Interplay Between the Host, the Human Microbiome, and Drug Metabolism
Robert G. Nichols, J. Peters, Andrew D. Patterson
2019Human Genomics61 citations Open access
Semantic Scholar
Vitamin D Regulates the Microbiota to Control the Numbers of RORγt/FoxP3+ Regulatory T Cells in the Colon
M. Cantorna, Yang-Ding Lin, Juhi Arora, S. Bora +3 more
2019Frontiers in Immunology50 citations Open access
Semantic Scholar
Metabolic impact of persistent organic pollutants on gut microbiota
Yuan Tian, Wei Gui, Bipin Rimal, Imhoi Koo +5 more
2020Gut microbes49 citations Open access
Semantic Scholar
Modulation of Colon Cancer by Nutmeg
Fei Li, Xiuwei Yang, K. Krausz, Robert G. Nichols +3 more
2015Journal of Proteome Research49 citations Open access
Semantic Scholar
Metatranscriptomic Analysis of the Mouse Gut Microbiome Response to the Persistent Organic Pollutant 2,3,7,8-Tetrachlorodibenzofuran
Robert G. Nichols, Jingtao Zhang, Jingwei Cai, I. Murray +4 more
2019Metabolites34 citations Open access
Semantic Scholar
The aryl hydrocarbon receptor as a moderator of host-microbiota communication
Li-Min Zhang, Robert G. Nichols, Andrew D. Patterson
2017Current Opinion in Toxicology33 citations Open access
Semantic Scholar
Prebiotic effects of white button mushroom (Agaricus bisporus) feeding on succinate and intestinal gluconeogenesis in C57BL/6 mice
Yuan Tian, Robert G. Nichols, P. Roy, Wei Gui +7 more
2018Journal of Functional Foods31 citations Open access
Semantic Scholar
The Aryl Hydrocarbon Receptor Activates Ceramide Biosynthesis in Mice Contributing to Hepatic Lipogenesis
Qing Liu, Li-Min Zhang, Erik L. Allman, T. Hubbard +9 more
2021Toxicology20 citations Open access
Semantic Scholar
A Quantitative HILIC–MS/MS Assay of the Metabolic Response of Huh-7 Cells Exposed to 2,3,7,8-Tetrachlorodibenzo-p-Dioxin
Qing Liu, Jingwei Cai, Robert G. Nichols, Yuan Tian +5 more
2019Metabolites14 citations Open access
Semantic Scholar
Persistent Organic Pollutants Modify Gut Microbiota–Host Metabolic Homeostasis in Mice Through Aryl Hydrocarbon Receptor Activation
Li-Min Zhang, Robert G. Nichols, Jared B. Correll, Iain A. Murray +9 more
2015Environmental Health Perspectives14 citations Open access
Semantic Scholar
Multiplatform Physiologic and Metabolic Phenotyping Reveals Microbial Toxicity
Jingwei Cai, Robert G. Nichols, Imhoi Koo, Zachary A. Kalikow +5 more
2018mSystems7 citations Open access
Semantic Scholar
Structural and Functional Analysis of the Gut Microbiome for Toxicologists
Robert G. Nichols, Jingwei Cai, Iain A. Murray, Imhoi Koo +3 more
2018Current Protocols in Toxicology7 citations Open access
Semantic Scholar
Omics Approaches To Probe Microbiota and Drug Metabolism Interactions.
Robert G. Nichols, Nicole E. Hume, Philip B. W. Smith, J. Peters +1 more
2016Chemical Research in Toxicology7 citations
Semantic Scholar
Gut Microbiota Increased by Omega‐3 Fatty Acids is Negatively Correlated with Hepatic Lipid Metabolism‐Associated Genes in mice with High Carbohydrate Diet‐Induced Steatosis
Kuan-Hsun Huang, Robert G. Nichols, Aswathy Sebastian, I. Albert +2 more
2017The FASEB Journal3 citations Open access
Semantic Scholar
Berberine Directly Impacts the Gut Microbiota to Promote Intestinal Farnesoid X Receptor Activation
Yuan Tian, Jingwei Cai, Wei Gui, Robert G. Nichols +5 more
20181 citations
Semantic Scholar
Vitamin A deficiency in mice results in a hypermetabolic state, dysbiosis and alterations in bacterial metabolism
Yuan Tian, Robert G. Nichols, Lindsay Snyer, Veronika Weaver +5 more
2017Journal of Immunology0 citations
Semantic Scholar
Intestinal FXR: A New Therapeutic Target for Nonalcoholic Fatty Liver Disease
S. Fang, J. M. Suh, Elizabeth Yu, O. Osborn +30 more
20150 citations
Semantic Scholar
Activation of the Aryl Hydrocarbon Receptor Modulates the Gut Microbiome
Robert G. Nichols
20140 citations
Semantic Scholar

Li-Min Zhang

×11

K. Krausz×8

F. Gonzalez×8

G. Perdew×8

Imhoi Koo×7

Cen Xie×6

Bipin Rimal×5

I. Murray×5