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C. Payne · SciRah

Researcher profile · Semantic Scholar

C. Payne

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C. Payne — researcher profile on SciRah

h-index: 29
Works: 53
Citations: 4,703

Most-cited papers

Common polymorphisms of CYP2C19 and CYP2C9 affect the pharmacokinetic and pharmacodynamic response to clopidogrel but not prasugrel
J. Brandt, S. Close, S. Iturria, C. Payne +5 more
2007Journal of Thrombosis and Haemostasis779 citations Open access
Semantic Scholar
A comparison of prasugrel and clopidogrel loading doses on platelet function: magnitude of platelet inhibition is related to active metabolite formation.
J. Brandt, C. Payne, S. Wiviott, G. Weerakkody +5 more
2007American Heart Journal583 citations
Semantic Scholar
Prasugrel achieves greater inhibition of platelet aggregation and a lower rate of non-responders compared with clopidogrel in aspirin-treated patients with stable coronary artery disease.
T. Jernberg, C. Payne, K. Winters, C. Darstein +5 more
2006European Heart Journal565 citations Open access
Semantic Scholar
Effects of the Proton Pump Inhibitor Lansoprazole on the Pharmacokinetics and Pharmacodynamics of Prasugrel and Clopidogrel
D. Small, N. A. Farid, C. Payne, G. Weerakkody +4 more
2008Journal of clinical pharmacology345 citations
Semantic Scholar
Cytochrome P450 3A Inhibition by Ketoconazole Affects Prasugrel and Clopidogrel Pharmacokinetics and Pharmacodynamics Differently
N. A. Farid, C. Payne, D. Small, K. Winters +5 more
2007Clinical pharmacology and therapy345 citations
Semantic Scholar
Tadalafil pharmacokinetics in healthy subjects.
S. Forgue, Beverley E. Patterson, A. Bedding, C. Payne +3 more
2006British Journal of Clinical Pharmacology276 citations Open access
Semantic Scholar
Increased Active Metabolite Formation Explains the Greater Platelet Inhibition With Prasugrel Compared to High-dose Clopidogrel
C. Payne, Y. Li, D. Small, C. Ernest +5 more
2007Journal of Cardiovascular Pharmacology179 citations Open access
Semantic Scholar
The use of the VerifyNow P2Y12 point-of-care device to monitor platelet function across a range of P2Y12 inhibition levels following prasugrel and clopidogrel administration
J. Jakubowski, C. Payne, Y. Li, J. Brandt +4 more
2008Thrombosis and Haemostasis129 citations
Semantic Scholar
Effect of Atorvastatin on the Pharmacokinetics and Pharmacodynamics of Prasugrel and Clopidogrel in Healthy Subjects
N. A. Farid, D. Small, C. Payne, J. Jakubowski +6 more
2008Pharmacotherapy96 citations
Semantic Scholar
Effect of Tadalafil on Cytochrome P450 3A4–mediated Clearance: Studies in Vitro and in Vivo
Barbara J. Ring, Beverley E. Patterson, M. Mitchell, M. Vandenbranden +8 more
2005Clinical pharmacology and therapy93 citations
Semantic Scholar
The Platelet Inhibitory Effects and Pharmacokinetics of Prasugrel After Administration of Loading and Maintenance Doses in Healthy Subjects
J. Jakubowski, C. Payne, J. Brandt, G. Weerakkody +5 more
2006Journal of Cardiovascular Pharmacology92 citations Open access
Semantic Scholar
A comparison of the antiplatelet effects of prasugrel and high-dose clopidogrel as assessed by VASP-phosphorylation and light transmission aggregometry
J. Jakubowski, C. Payne, Y. Li, N. A. Farid +4 more
2007Thrombosis and Haemostasis83 citations Open access
Semantic Scholar
Prasugrel pharmacokinetics and pharmacodynamics in subjects with moderate renal impairment and end‐stage renal disease
D. Small, R. Wrishko, C. Ernest, L. Ni +8 more
2009Journal of Clinical Pharmacy and Therapeutics75 citations Open access
Semantic Scholar
The pharmacokinetics and pharmacodynamics of prasugrel in healthy Chinese, Japanese, and Korean subjects compared with healthy Caucasian subjects
D. Small, P. Kothare, E. Yuen, D. R. Lachno +8 more
2010European Journal of Clinical Pharmacology74 citations
Semantic Scholar
Comparison of speed of onset of platelet inhibition after loading doses of clopidogrel versus prasugrel in healthy volunteers and correlation with responder status.
G. Weerakkody, J. Jakubowski, J. Brandt, N. A. Farid +5 more
2007American Journal of Cardiology70 citations
Semantic Scholar
Effects of gender, age, diabetes mellitus and renal and hepatic impairment on tadalafil pharmacokinetics.
S. Forgue, D. Phillips, A. Bedding, C. Payne +4 more
2007British Journal of Clinical Pharmacology65 citations Open access
Semantic Scholar
Effect of Intrinsic and Extrinsic Factors on the Clinical Pharmacokinetics and Pharmacodynamics of Prasugrel
D. Small, N. A. Farid, C. Payne, C. Konkoy +3 more
2010Clinical Pharmacokinetics61 citations
Semantic Scholar
Effect of ranitidine on the pharmacokinetics and pharmacodynamics of prasugrel and clopidogrel
D. Small, N. A. Farid, Y. Li, C. Ernest +3 more
2008Current Medical Research and Opinion60 citations
Semantic Scholar
Inhibition of platelet aggregation with prasugrel and clopidogrel: An integrated analysis in 846 subjects
Y. Li, L. Ni, J. T. Brandt, D. Small +6 more
2009Platelets59 citations
Semantic Scholar
Prasugrel, a New Thienopyridine Antiplatelet Drug, Weakly Inhibits Cytochrome P450 2B6 in Humans
N. A. Farid, C. Payne, C. Ernest, Y. Li +3 more
2008Journal of clinical pharmacology58 citations
Semantic Scholar
Dose-Dependent Inhibition of Human Platelet Aggregation by Prasugrel and its Interaction With Aspirin in Healthy Subjects
J. Jakubowski, C. Payne, G. Weerakkody, J. Brandt +5 more
2007Journal of Cardiovascular Pharmacology58 citations Open access
Semantic Scholar
A Comparison of the VerifyNow P2Y12 Point-of-Care Device and Light Transmission Aggregometry to Monitor Platelet Function with Prasugrel and Clopidogrel: An Integrated Analysis
J. Jakubowski, Y. Li, D. Small, C. Payne +3 more
2010Journal of Cardiovascular Pharmacology52 citations
Semantic Scholar
Switching directly to prasugrel from clopidogrel results in greater inhibition of platelet aggregation in aspirin-treated subjects
C. Payne, Y. Li, J. Brandt, J. Jakubowski +4 more
2008Platelets49 citations
Semantic Scholar
Pharmacodynamics and pharmacokinetics of single doses of prasugrel 30 mg and clopidogrel 300 mg in healthy Chinese and white volunteers: an open-label trial.
D. Small, C. Payne, P. Kothare, E. Yuen +11 more
2010Clinical Therapeutics46 citations
Semantic Scholar
Pharmacokinetics and pharmacodynamics of the cathepsin S inhibitor, LY3000328, in healthy subjects.
C. Payne, M. Deeg, M. Chan, L. Tan +3 more
2014British Journal of Clinical Pharmacology41 citations Open access
Semantic Scholar
Greater Inhibition of Platelet Aggregation and Reduced Response Variability With Prasugrel Versus Clopidogrel: An Integrated Analysis
G. Weerakkody, J. Jakubowski, J. Brandt, C. Payne +2 more
2007Journal of Cardiovascular Pharmacology and Therapeutics39 citations Open access
Semantic Scholar
Integrated Analysis of Pharmacokinetic Data Across Multiple Clinical Pharmacology Studies of Prasugrel, a New Thienopyridine Antiplatelet Agent
D. Small, Y. Li, C. Ernest, John H. April +5 more
2011Journal of clinical pharmacology36 citations
Semantic Scholar
Effect of rifampin on the pharmacokinetics and pharmacodynamics of prasugrel in healthy male subjects
N. A. Farid, J. Jakubowski, C. Payne, Y. Li +6 more
2009Current Medical Research and Opinion34 citations
Semantic Scholar
A phase 1 study of prasugrel in patients with sickle cell disease: effects on biomarkers of platelet activation and coagulation.
J. Jakubowski, Chun-Mei Zhou, S. Jurcevic, K. Winters +6 more
2014Thrombosis Research31 citations
Semantic Scholar
Ixekizumab Citrate-Free Formulation: Results from Two Clinical Trials
S. Chabra, B. Gill, G. Gallo, Dan-Ting Zhu +4 more
2022Advances in Therapy29 citations Open access
Semantic Scholar
Subcutaneous Injection Site Pain of Formulation Matrices
G. Shi, Karthik Pisupati, J. Parker, V. Corvari +4 more
2021Pharmaceutical Research29 citations
Semantic Scholar
Clopidogrel poor responders: An objective definition based on Bayesian classification
G. Weerakkody, J. Brandt, C. Payne, J. Jakubowski +2 more
2007Platelets29 citations
Semantic Scholar
Pharmacokinetics and pharmacodynamics of prasugrel in subjects with moderate liver disease
D. Small, N. A. Farid, Y.-G. Li, C. Ernest +3 more
2009Journal of Clinical Pharmacy and Therapeutics26 citations Open access
Semantic Scholar
A phase 1 study of prasugrel in patients with sickle cell disease: pharmacokinetics and effects on ex vivo platelet reactivity.
J. Jakubowski, Chun-Mei Zhou, D. Small, K. Winters +6 more
2013British Journal of Clinical Pharmacology23 citations Open access
Semantic Scholar
Pharmacokinetics, Safety, and Tolerability of Single‐ and Multiple‐Dose Once‐Daily Baricitinib in Healthy Chinese Subjects: A Randomized Placebo‐Controlled Study
Xia Zhao, Xiao-Yan Sheng, C. Payne, X. Zhang +2 more
2020Clinical pharmacology in drug development22 citations Open access
Semantic Scholar
Dose-normalised pharmacokinetics of tadalafil administered as a single dose to healthy volunteers
B. Patterson, A. Bedding, Hayley Jewell, C. Payne +1 more
200222 citations
Semantic Scholar
Effect of Age on the Pharmacokinetics and Pharmacodynamics of Prasugrel during Multiple Dosing
D. Small, R. Wrishko, C. Ernest, L. Ni +5 more
2009Drugs & Aging14 citations
Semantic Scholar
The effect of prasugrel on ADP-stimulated markers of platelet activation in patients with sickle cell disease
J. Jakubowski, Chun-Mei Zhou, K. Winters, D. R. Lachno +5 more
2015Platelets13 citations
Semantic Scholar
Absence of "rebound" platelet hyperreactivity following cessation of prasugrel
J. Jakubowski, Y. Li, C. Payne, D. Small +1 more
2011Thrombosis and Haemostasis13 citations
Semantic Scholar
Pharmacokinetic and Pharmacodynamic Effects of Prasugrel in Healthy Korean Males
K. Yu, Kyung-Woo Park, Ronan P. Kelly, N. Gu +5 more
2013Journal of Cardiovascular Pharmacology9 citations
Semantic Scholar
Pharmacokinetics, Safety, and Efficacy of Ixekizumab in Chinese Patients with Moderate-to-Severe Plaque Psoriasis: A Phase 1, Single- and Multiple-Dose Study.
M. Zheng, Xiang Chen, Feng Wang, Ji-Su Chen +7 more
2023Advances in Therapy4 citations
Semantic Scholar
The GLP-1 analogue, LY307161, potently lowers post prandial blood glucose in subjects with type 2 diabetes
S. Pascoe, C. Payne, M. Trautmann
20003 citations
Semantic Scholar
A Phase 1 Study of Prasugrel in Subjects with Sickle Cell Disease: Effects on In Vivo Markers of Platelet Activation and of Coagulation
J. Jakubowski, Chun-Mei Zhou, D. Small, K. Winters +5 more
20112 citations
Semantic Scholar
THU0199 PHARMACOKINETICS, SAFETY AND TOLERABILITY OF SINGLE- AND MULTIPLE- DOSE ONCE-DAILY BARICITINIB IN CHINESE HEALTHY VOLUNTEERS – A RANDOMIZED PLACEBO-CONTROLLED STUDY
Xia Zhao, C. Payne, Feng Wang, Yi-Min Cui
2019Poster Presentations1 citations Open access
Semantic Scholar
Disposition of [14C]LY2606368 following intravenous administration in patients with advanced and/or metastatic solid tumours
E. Wickremsinhe, S. Hynes, C. Payne, Yingying Guo +1 more
2019Xenobiotica; the fate of foreign compounds in biological systems1 citations
Semantic Scholar
14066 Pharmacokinetics, safety and efficacy of ixekizumab in Chinese patients with plaque psoriasis: Results from a phase 1 single- and multiple-dose study
Feng Wang, M. Zheng, Xiang Chen, Ji-Su Chen +4 more
20200 citations
Semantic Scholar
A Phase 1 Study of Prasugrel in Subjects with Sickle Cell Disease: Impact on Ex Vivo Platelet Reactivity
J. Jakubowski, Chun-Mei Zhou, D. Small, K. Winters +5 more
20110 citations
Semantic Scholar
Switching to prasugrel from clopidogrel results in greater inhibition of platelet aggregation in aspirin-treated subjects
J. Jakubowski, C. Payne, Y. Li, J. Brandt +4 more
20070 citations
Semantic Scholar
A 60-mg loading dose of prasugrel achieves greater platelet inhibition than 300-mg and 600-mg loading doses of clopidogrel
J. Jakubowski, C. Payne, Y. Li, D. Salazar +4 more
20070 citations
Semantic Scholar
Coronary heart disease Prasugrel achieves greater inhibition of platelet aggregation and a lower rate of non-responders compared with clopidogrel in aspirin-treated patients with stable coronary artery disease
T. Jernberg, C. Payne, K. Winters, C. Darstein +5 more
20060 citations
Semantic Scholar

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