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R. Wrishko · SciRah

Researcher profile · Semantic Scholar

R. Wrishko

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R. Wrishko — researcher profile on SciRah

h-index: 18
Works: 44
Citations: 1,255

Most-cited papers

Tadalafil pharmacokinetics in healthy subjects.
S. Forgue, Beverley E. Patterson, A. Bedding, C. Payne +3 more
2006British Journal of Clinical Pharmacology276 citations Open access
Semantic Scholar
Pharmacokinetic Interaction Between Tadalafil and Bosentan in Healthy Male Subjects
R. Wrishko, J. Dingemanse, A. Yu, C. Darstein +2 more
2006Journal of clinical pharmacology114 citations Open access
Semantic Scholar
Population Pharmacokinetic Analyses to Evaluate the Influence of Intrinsic and Extrinsic Factors on Exposure of Prasugrel Active Metabolite in TRITON‐TIMI 38
R. Wrishko, C. Ernest, D. Small, Y. Li +9 more
2009Journal of clinical pharmacology83 citations
Semantic Scholar
Prasugrel pharmacokinetics and pharmacodynamics in subjects with moderate renal impairment and end‐stage renal disease
D. Small, R. Wrishko, C. Ernest, L. Ni +8 more
2009Journal of Clinical Pharmacy and Therapeutics75 citations Open access
Semantic Scholar
On-the-Road Driving Performance the Morning after Bedtime Use of Suvorexant 20 and 40 mg: A Study in Non-Elderly Healthy Volunteers.
A. Vermeeren, Hong Sun, E. Vuurman, S. Jongen +10 more
2015Sleep70 citations Open access
Semantic Scholar
CYP2D6 metabolizer status and atomoxetine dosing in children and adolescents with ADHD.
P. Trzepacz, D. Williams, P. Feldman, R. Wrishko +2 more
2008European Neuropsychopharmacology67 citations
Semantic Scholar
Effects of gender, age, diabetes mellitus and renal and hepatic impairment on tadalafil pharmacokinetics.
S. Forgue, D. Phillips, A. Bedding, C. Payne +4 more
2007British Journal of Clinical Pharmacology65 citations Open access
Semantic Scholar
Safety, efficacy, and pharmacokinetic overview of low-dose daily administration of tadalafil.
R. Wrishko, S. Sorsaburu, David G. Wong, Andrew B. Strawbridge +1 more
2009Journal of Sexual Medicine64 citations
Semantic Scholar
Population pharmacokinetics and pharmacodynamics of prasugrel and clopidogrel in aspirin-treated patients with stable coronary artery disease
C. Ernest, D. Small, S. Rohatagi, D. E. Salazar +3 more
2008Journal of Pharmacokinetics and Pharmacodynamics54 citations
Semantic Scholar
Vancomycin Pharmacokinetics and Bayesian Estimation in Pediatric Patients
R. Wrishko, M. Levine, Dominique Khoo, P. Abbott +1 more
2000Therapeutic Drug Monitoring53 citations
Semantic Scholar
Relationship Between Exposure to Prasugrel Active Metabolite and Clinical Outcomes in the TRITON‐TIMI 38 Substudy
Jeffrey S. Riesmeyer, D. E. Salazar, G. Weerakkody, L. Ni +7 more
2012Journal of clinical pharmacology50 citations
Semantic Scholar
On-the-road driving performance the morning after bedtime use of suvorexant 15 and 30 mg in healthy elderly
A. Vermeeren, E. Vets, E. Vuurman, A. V. Van Oers +10 more
2016Psychopharmacology43 citations Open access
Semantic Scholar
Pharmacokinetics of sugammadex in subjects with moderate and severe renal impairment .
K. Min, K. Lasseter, T. Marbury, R. Wrishko +5 more
2017International journal of clinical pharmacology and therapeutics30 citations
Semantic Scholar
Sugammadex for reversal of neuromuscular blockade in pediatric patients: Results from a phase IV randomized study
T. Voss, Aobo Wang, Matthew DeAngelis, Marcel Speek +4 more
2021Paediatric anaesthesia29 citations
Semantic Scholar
Safety, Tolerability, and Pharmacokinetics of Suvorexant: A Randomized Rising-Dose Trial in Healthy Men
Ka L. Yee, J. McCrea, D. Panebianco, Wen Liu +4 more
2018Clinical drug investigation24 citations
Semantic Scholar
Population Pharmacokinetics and Pharmacodynamics of Bezlotoxumab in Adults with Primary and Recurrent Clostridium difficile Infection
Ka L. Yee, H. Kleijn, T. Kerbusch, R. P. Matthews +3 more
2018Antimicrobial Agents and Chemotherapy21 citations Open access
Semantic Scholar
Effect of CYP3A Inhibition and Induction on the Pharmacokinetics of Suvorexant: Two Phase I, Open‑Label, Fixed-Sequence Trials in Healthy Subjects
R. Wrishko, J. McCrea, Ka L. Yee, Wen Liu +5 more
2019Clinical drug investigation19 citations Open access
Semantic Scholar
Investigation of a possible interaction between ciprofloxacin and cyclosporine in renal transplant patients.
R. Wrishko, M. Levine, Dennis R. N. Primmett, Susan Kim +4 more
1997Transplantation19 citations Open access
Semantic Scholar
Effect of Age on the Pharmacokinetics and Pharmacodynamics of Prasugrel during Multiple Dosing
D. Small, R. Wrishko, C. Ernest, L. Ni +5 more
2009Drugs & Aging14 citations
Semantic Scholar
Sugammadex for Reversal of Neuromuscular Blockade in Neonates and Infants Less than 2 Years Old: Results from a Phase IV Randomized Clinical Trial
Edith Mensah-Osman, Yuki Mukai, Aobo Wang, Maria Matuszczak +7 more
2025Anesthesiology11 citations Open access
Semantic Scholar
Effect of Vorapaxar Alone and in Combination with Aspirin on Bleeding Time and Platelet Aggregation in Healthy Adult Subjects
W. Kraft, Jocelyn Gilmartin, D. Chappell, F. Gheyas +7 more
2016Clinical and Translational Science10 citations Open access
Semantic Scholar
A Pharmacokinetic Study of Cyclosporin (Sandimmune®)
D. Primmett, M. Levine, R. Wrishko, P. Keown
19979 citations
Semantic Scholar
The Bioequivalence and Effect of Food on the Pharmacokinetics of a Fixed‐Dose Combination Tablet Containing Rosuvastatin and Ezetimibe in Healthy Japanese Subjects
Chisato Nishida, Yuki Matsumoto, Katsukuni Fujimoto, Masayoshi Shirakawa +3 more
2019Clinical and Translational Science8 citations Open access
Semantic Scholar
Model‐Informed Dose Justifications of Posaconazole in Japanese Patients for Prophylaxis and Treatment Against Fungal Infection
Takashi Iwasa, Camila de Almeida, F. Fauchet, Gregory A. Winchell +4 more
2022Journal of clinical pharmacology7 citations
Semantic Scholar
Pharmacokinetics of Sugammadex Dosed by Actual and Ideal Body Weight in Patients With Morbid Obesity Undergoing Surgery
Kate Mostoller, R. Wrishko, L. Maganti, W. Herring +1 more
2020Clinical and Translational Science7 citations Open access
Semantic Scholar
Pharmacokinetic and Exposure Response Analysis of the Double-Blind Randomized Study of Posaconazole and Voriconazole for Treatment of Invasive Aspergillosis
J. Maertens, G. Rahav, Dong-Gun Lee, Shariq Haider +8 more
2023Clinical drug investigation6 citations Open access
Semantic Scholar
Pharmacokinetics of intravenous daptomycin in Japanese pediatric patients: Pharmacokinetic comparisons supporting dosing recommendations in Japanese pediatric patients.
Mikio Ishii, Yuji Orito, Mari Shiomi, R. Wrishko +1 more
2023Journal of Infection and Chemotherapy5 citations Open access
Semantic Scholar
A time-to-event analysis of the exposure–response relationship for bezlotoxumab concentrations and CDI recurrence
Ka L. Yee, H. Kleijn, S. Zajic, M. Dorr +1 more
2020Journal of Pharmacokinetics and Pharmacodynamics5 citations
Semantic Scholar
A population pharmacokinetic model for posaconazole intravenous solution and oral powder for suspension formulations in pediatric patients with neutropenia
Gregory A. Winchell, R. de Greef, A. Ouerdani, F. Fauchet +4 more
2024Antimicrobial Agents and Chemotherapy4 citations Open access
Semantic Scholar
Modeling and Simulation Analysis of Aprepitant Pharmacokinetics in Pediatric Patients With Postoperative or Chemotherapy-Induced Nausea and Vomiting.
A. Chain, R. Wrishko, G. Vasilinin, Samer Mouksassi
2020The Journal of Pediatric Pharmacology and Therapeutics4 citations Open access
Semantic Scholar
Abstract 4001: Relationship between Exposure to the Prasugrel Active Metabolite with TIMI Major/Minor Bleeding in TRITON-TIMI 38
D. Salazar, C. Ernest, R. Wrishko, G. Weerakkody +9 more
20084 citations
Semantic Scholar
Assessment of Bezlotoxumab Immunogenicity
Diana Montgomery, R. P. Matthews, Ka L. Yee, L. Tobias +2 more
2020Clinical pharmacology in drug development3 citations
Semantic Scholar
Prediction of Prasugrel Active Metabolite Concentrations From 2 Downstream Inactive Metabolite Concentrations Using Multilinear Regression Analysis
C. Ernest, Michael A. Heathman, R. Wrishko
2009Journal of clinical pharmacology3 citations
Semantic Scholar
Population Pharmacokinetic Model Assessment of the Effects of Body Weight on Risk of Drug–Drug Interactions After Posaconazole Discontinuation
R. Wrishko, T. Bateman, Matthew G. Johnson, P. Kothare
2026Clinical and Translational Science1 citations Open access
Semantic Scholar
Tadalafil Improves Exercise Capacity in Patients with Pulmonary Arterial Hypertension across the Interdosing Interval.
N. Galie', A. Beardsworth, R. Wrishko, H. Ghofrani
2009Asian Test Symposium1 citations
Semantic Scholar
Plasma and breast milk pharmacokinetics of suvorexant in healthy lactating women.
J. McCrea, Andrew Litovsky, Prachi K. Wickremasingha, Nairita Ghosal +7 more
2026British Journal of Clinical Pharmacology0 citations Open access
Semantic Scholar
Predicted Bezlotoxumab Exposure in Patients Who Have Received a Hematopoietic Stem Cell Transplant.
Camila de Almeida, Michael Wong, H. Kleijn, R. Wrishko
2023Clinical Therapeutics0 citations
Semantic Scholar
Correction text
R. Wrishko, J. McCrea, Ka L. Yee, Wen Liu +5 more
2019Clinical drug investigation0 citations Open access
Semantic Scholar
Abstract 527: Vorapaxar Does Not Increase Bleeding Time
W. Kraft, Jocelyn Gilmartin, D. Chappell, S. Nagalla +4 more
20160 citations
Semantic Scholar
S.27.02 Orexin receptor antagonists and insomnia treatment: state of the art
Anthony L. Gotter, Paul J. Coleman, S. Kuduk, P. Tannenbaum +6 more
20140 citations
Semantic Scholar
Population pharmacokinetics and Bayesian forecasting of vancomycin in neonates requiring intensive care
R. Wrishko
20020 citations
Semantic Scholar
Inhibition of Mycelial Growth by Methotrexate in Neurospora crassa Wild Type and Mutants Deficient in Folylpolyglutamate Synthase
R. Wrishko, E. Cossins
19980 citations Open access
Semantic Scholar
The role of polyglutamylation in the cytotoxicity of methotrexate in neurospora crassa
R. Wrishko
19960 citations
Semantic Scholar
Model-Informed Dose Justifications and Clinical Pharmacology Strategy of Posaconazole in Japanese Patients for Prophylaxis and Treatment Against Fungal Infection
Chihiro Hasegawa, Takashi Iwasa, Hiroyuki Yoshitsugu, R. Wrishko
Proceedings of the American Conference of Pharmacometrics 20240 citations Open access
Semantic Scholar

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C. Ernest×7
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C. Ernest — researcher profile on SciRah
D. Small×6
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J. McCrea×6
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Ka L. Yee×6
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D. E. Salazar — researcher profile on SciRah

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L. Ni — researcher profile on SciRah

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C. Payne — researcher profile on SciRah

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Y. Li — researcher profile on SciRah

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W. Kraft — researcher profile on SciRah

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D. Phillips — researcher profile on SciRah

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M. Mitchell — researcher profile on SciRah

G. Weerakkody×3

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G. Weerakkody — researcher profile on SciRah