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K. Barck · SciRah

Researcher profile · Semantic Scholar

K. Barck

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K. Barck — researcher profile on SciRah

h-index: 22
Works: 47
Citations: 2,651

Most-cited papers

Complement C3 Is Activated in Human AD Brain and Is Required for Neurodegeneration in Mouse Models of Amyloidosis and Tauopathy.
Tiffany Wu, Borislav Dejanovic, Vineela Gandham, Alvin Gogineni +18 more
2019Cell Reports421 citations Open access
Semantic Scholar
Specific Btk inhibition suppresses B cell- and myeloid cell-mediated arthritis.
J. D. Di Paolo, Tao Huang, M. Balazs, J. Barbosa +27 more
2011Nature Chemical Biology329 citations Open access
Semantic Scholar
Trem2 restrains the enhancement of tau accumulation and neurodegeneration by β-amyloid pathology.
Seung-Hye Lee, William J. Meilandt, Luke Xie, Vineela Gandham +14 more
2021Neuron222 citations Open access
Semantic Scholar
Function of CSF1 and IL34 in Macrophage Homeostasis, Inflammation, and Cancer
Wei-Yu Lin, Daqi Xu, Cary D. Austin, P. Caplazi +44 more
2019Frontiers in Immunology164 citations Open access
Semantic Scholar
Targeted depletion of lymphotoxin-α–expressing TH1 and TH17 cells inhibits autoimmune disease
E. Chiang, Ganesh A. Kolumam, Xin Yu, M. Francesco +16 more
2009Nature Medicine157 citations
Semantic Scholar
Host-Detrimental Role of Esx-1-Mediated Inflammasome Activation in Mycobacterial Infection
Fredric Carlsson, Janice Kim, C. Dumitru, K. Barck +4 more
2010PLoS Pathogens154 citations Open access
Semantic Scholar
A rare population of CD24+ITGB4+Notchhi cells drives tumor propagation in NSCLC and requires Notch3 for self-renewal
Yan-Yan Zheng, C. C. de la Cruz, L. Sayles, Chris Alleyne-Chin +14 more
2013Cancer Cell153 citations Open access
Semantic Scholar
A TRPA1 inhibitor suppresses neurogenic inflammation and airway contraction for asthma treatment
Alessia Balestrini, Victory Joseph, M. Dourado, Rebecca M. Reese +56 more
2021Journal of Experimental Medicine118 citations Open access
Semantic Scholar
Mouse Models of Rheumatoid Arthritis
P. Caplazi, M. Baca, K. Barck, R. Carano +4 more
2015Veterinary Pathology-Supplement104 citations Open access
Semantic Scholar
A novel inhibitor of the alternative pathway of complement reverses inflammation and bone destruction in experimental arthritis
K. Katschke, K. Helmy, M. Steffek, Hong-Kang Xi +11 more
2007Journal of Experimental Medicine98 citations Open access
Semantic Scholar
Chondroitin sulfate synthase 1 (Chsy1) is required for bone development and digit patterning.
D. Wilson, Khanhky Phamluong, Wei-Yu Lin, K. Barck +5 more
2012Developmental Biology85 citations Open access
Semantic Scholar
Quantification of cortical bone loss and repair for therapeutic evaluation in collagen-induced arthritis, by micro-computed tomography and automated image analysis.
K. Barck, Wyne P. Lee, L. Diehl, J. Ross +6 more
2004Arthritis & Rheumatism83 citations
Semantic Scholar
Anti‐VEGF antibody therapy does not promote metastasis in genetically engineered mouse tumour models
Mallika Singh, S. Couto, W. Forrest, A. Lima +17 more
2012Journal of Pathology79 citations
Semantic Scholar
Targeting the PI3K Pathway in the Brain—Efficacy of a PI3K Inhibitor Optimized to Cross the Blood–Brain Barrier
L. Salphati, T. Heffron, B. Alicke, M. Nishimura +19 more
2012Clinical Cancer Research68 citations Open access
Semantic Scholar
The kinase TPL2 activates ERK and p38 signaling to promote neutrophilic inflammation
K. Senger, Victoria Pham, E. Varfolomeev, Jason A. Hackney +34 more
2017Science Signaling57 citations
Semantic Scholar
Quantification of viable tumor microvascular characteristics by multispectral analysis
L. Berry, K. Barck, M. Go, J. Ross +11 more
2008Magnetic Resonance in Medicine53 citations Open access
Semantic Scholar
Distribution of the Phosphatidylinositol 3-Kinase Inhibitors Pictilisib (GDC-0941) and GNE-317 in U87 and GS2 Intracranial Glioblastoma Models—Assessment by Matrix-Assisted Laser Desorption Ionization Imaging
L. Salphati, S. Shahidi-Latham, Cristine Quiason, K. Barck +6 more
2014Drug Metabolism And Disposition46 citations Open access
Semantic Scholar
Muscle specific kinase (MuSK) activation preserves neuromuscular junctions in the diaphragm but is not sufficient to provide a functional benefit in the SOD1G93A mouse model of ALS.
Arundhati Sengupta-Ghosh, Sara L. Dominguez, Luke Xie, K. Barck +17 more
2019Neurobiology of Disease41 citations Open access
Semantic Scholar
Development and Preclinical Characterization of a Humanized Antibody Targeting CXCL12
Cuiling Zhong, Jianyong Wang, Bing Li, H. Xiang +20 more
2013Clinical Cancer Research39 citations Open access
Semantic Scholar
Anti-EGFL7 antibodies enhance stress-induced endothelial cell death and anti-VEGF efficacy.
L. Johnson, M. Huseni, Tanya Smyczek, A. Lima +24 more
2013Journal of Clinical Investigation38 citations Open access
Semantic Scholar
Multimodal microvascular imaging reveals that selective inhibition of class I PI3K is sufficient to induce an antivascular response.
D. Sampath, J. Oeh, S. Wyatt, T. Cao +19 more
2013Neoplasia29 citations Open access
Semantic Scholar
Micro-CT imaging and structural analysis of glomeruli in a model of Adriamycin-induced nephropathy.
Luke Xie, G. Koukos, K. Barck, O. Foreman +6 more
2019AJP - Renal Physiology27 citations Open access
Semantic Scholar
Automated segmentation of lungs and lung tumors in mouse micro-CT scans
G. Ferl, K. Barck, Jasmine Patil, S. Jemaa +6 more
2022iScience22 citations Open access
Semantic Scholar
Fully-automated, high-throughput micro-computed tomography analysis of body composition enables therapeutic efficacy monitoring in preclinical models
S. Wyatt, K. Barck, L. Kates, José Zavala-Solorio +4 more
2015International Journal of Obesity16 citations
Semantic Scholar
Viable tumor tissue detection in murine metastatic breast cancer by whole‐body MRI and multispectral analysis
K. Barck, B. Willis, J. Ross, D. French +2 more
2009Magnetic Resonance in Medicine14 citations
Semantic Scholar
Quantification of Tumor Burden in a Genetically Engineered Mouse Model of Lung Cancer by Micro-CT and Automated Analysis
K. Barck, H. Bou-Reslan, Ujjawal Rastogi, Timothy Sakhuja +7 more
2015Translational Oncology13 citations Open access
Semantic Scholar
Kidney segmentation using 3D U-Net localized with Expectation Maximization
O. Bazgir, K. Barck, R. Carano, R. Weimer +1 more
2020Southwest Symposium on Image Analysis and Interpretation6 citations Open access
Semantic Scholar
Preclinical safety profile of a depleting antibody against CRTh2 for asthma: Well tolerated despite unexpected CRTh2 expression on vascular pericytes in the central nervous system and gastric mucosa
Cary D. Austin, Tao Huang, Neeraj Sharma, Shannon Liu +17 more
2016Toxicological Sciences6 citations
Semantic Scholar
Abstract 3295: Inhibiting vascular morphogenesis in tumors: EGFL7 as a novel therapeutic target
Stacey Yeung, Tanya Smyczek, Jason H. Cheng, A. Lima +15 more
20115 citations
Semantic Scholar
Diffusion Tensor MRI is sensitive to fibrotic injury in a mouse model of oxalate induced chronic kidney disease.
Rohan S. Virgincar, Aaron K Wong, K. Barck, Joshua Webster +13 more
2024AJP - Renal Physiology4 citations
Semantic Scholar
RIT1M90I is a driver of lung adenocarcinoma tumorigenesis and resistance to targeted therapy.
Ashley V. DiMarco, Mirunalini Ravichandran, Jeff Lau, A. Lima +16 more
2025Cancer Research2 citations
Semantic Scholar
Lung-innervating neurons expressing Tmc3 can induce broncho-constriction and dilation with direct consequences for the respiratory cycle
Jens Kortmann, Kevin Huang, Ming-Chi Tsai, K. Barck +14 more
2023bioRxiv2 citations Open access
Semantic Scholar
Abstract 6849: RIT1M90I is a driver of lung adenocarcinoma tumorigenesis and resistance to targeted therapy
Ashley V. DiMarco, Mirunalini Ravichandran, Jeff Lau, A. Lima +14 more
2025Cancer Research1 citations
Semantic Scholar
LAB-EXPERIMENTAL (PRE-CLINICAL) THERAPEUTICS AND PHARMACOLOGY
Fa Yang, Bo Zhang, Duo Zhou, Bie Li +323 more
20121 citations Open access
Semantic Scholar
Hypothalamic oligodendrocytes regulate systemic energy balance through Notch-dependent state transitions
Simona Hankeová, Margaret Hayne, Mathijs P. Verhagen, Greg Farber +15 more
2026bioRxiv0 citations Open access
Semantic Scholar
D29-25 Positron Emission Tomography (PET) Tracking of Lung Progenitor Cell Engraftment in Bleomycin-Injured Mouse Lungs
A. Marques, A. Ogasawara, J. Yun, P. Dragovich +16 more
2026American Journal of Respiratory and Critical Care Medicine0 citations
Semantic Scholar
Cross-modality network phenotyping: a multivariate MRI biomarker signature predicts spatial pathology and clinical severity in EAE
Rohan S. Virgincar, M. Choy, S. Jeet, Hunter Martinez +8 more
2026Frontiers in Neurology0 citations Open access
Semantic Scholar
Corrigendum to "Muscle specific kinase (MuSK) activation preserves neuromuscular junctions in the diaphragm but is not sufficient to provide a functional benefit in the SOD1G93A mouse model of ALS" Neurobiology of Disease 124 (2019) 340-352.
Arundhati Sengupta-Ghosh, Sara L. Dominguez, Luke Xie, K. Barck +18 more
2019Neurobiology of Disease0 citations Open access
Semantic Scholar
This information is current as Inflammatory Arthritis Negatively Regulates Mouse α PILR Zarrin
Yong-Liang Sun, P. Caplazi, Juan Zhang, Anita Mazloom +27 more
20140 citations
Semantic Scholar
DMD057513 1110..1116
L. Salphati, S. Shahidi-Latham, Cristine Quiason, K. Barck +6 more
20140 citations
Semantic Scholar
Cancer Therapy : Preclinical Development and Preclinical Characterization of a Humanized Antibody Targeting CXCL 12
Cuiling Zhong, Jianyong Wang, Bing Li, H. Xiang +20 more
20130 citations
Semantic Scholar
Characterization of Transgenic Mouse Models of Alzheimer ' s Disease by Fully Automated Analysis of Brain MRI
K. Barck, Kim Malesky, Vineela Gandham, M. Hedehus +7 more
20120 citations
Semantic Scholar
360 Efficacy of a Brain-penetrant PI3K/mTOR Inhibitor in Orthotopic Models of Glioblastoma
L. Salphati, T. Heffron, B. Alicke, K. Barck +6 more
20120 citations
Semantic Scholar
466 DISCUSSION PI3K inhibition is necessary and sufficient to induce an antiangiogenic response in vivo based on suppression of tumor vascular structure
D. Sampath, T. Cao, J. Oeh, K. Barck +6 more
20100 citations
Semantic Scholar
DCE-MRI of genetic mouse model of lung cancer
K. Barck, A. Lima, T. Cao, R. Molina +4 more
20100 citations
Semantic Scholar
Multimodal Imaging of a Dual PI 3 K / mTOR Inhibitor Demonstrates Strong Effects on Vascular Function
S. Wyatt, K. Barck, J. Oeh, H. Bou-Reslan +5 more
20100 citations
Semantic Scholar
Determining the conditions for robust acidoCEST MRI to measure extracellular pH in tumors in vivo
Rohan S. Virgincar, K. Barck, M. Go, Geoffrey Del Rosario +13 more
ISMRM Annual Meeting0 citations
Semantic Scholar

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