Tanya Smyczek

Most-cited papers

1. EGFL7 regulates the collective migration of endothelial cells by restricting their spatial distribution

   Maike Schmidt, Kim Paes, A. De Mazière, Tanya Smyczek +7 more

   2007Development203 citations

   Semantic Scholar

   Save

2. MAP4K4 regulates integrin-FERM binding to control endothelial cell motility

   P. Vitorino, Stacey Yeung, A. Crow, J. Bakke +8 more

   2015Nature136 citations

   Semantic Scholar

   Save

3. The Jak1 SH2 Domain Does Not Fulfill a Classical SH2 Function in Jak/STAT Signaling but Plays a Structural Role for Receptor Interaction and Up-regulation of Receptor Surface Expression*

   Simone Radtke, S. Haan, A. Jorissen, H. Hermanns +6 more

   2005Journal of Biological Chemistry95 citations Open access

   Semantic Scholar

   Save

4. Rasip1 regulates vertebrate vascular endothelial junction stability through Epac1-Rap1 signaling.

   Christopher W. Wilson, Leon H. Parker, Christopher J. Hall, Tanya Smyczek +12 more

   2013Blood56 citations Open access

   Semantic Scholar

   Save

5. Discovery of selective 4-Amino-pyridopyrimidine inhibitors of MAP4K4 using fragment-based lead identification and optimization.

   Terry D. Crawford, C. Ndubaku, Hui-Fen Chen, J. Boggs +18 more

   2014Journal of Medicinal Chemistry48 citations Open access

   Semantic Scholar

   Save

6. Structure-Based Design of GNE-495, a Potent and Selective MAP4K4 Inhibitor with Efficacy in Retinal Angiogenesis.

   C. Ndubaku, Terry D. Crawford, Hui-Fen Chen, J. Boggs +20 more

   2015ACS Medicinal Chemistry Letters46 citations Open access

   Semantic Scholar

   Save

7. Anti-EGFL7 antibodies enhance stress-induced endothelial cell death and anti-VEGF efficacy.

   L. Johnson, M. Huseni, Tanya Smyczek, A. Lima +24 more

   2013Journal of Clinical Investigation38 citations Open access

   Semantic Scholar

   Save

8. The role of Egfl7 in vascular morphogenesis.

   Maike Schmidt, A. De Mazière, Tanya Smyczek, A. Gray +6 more

   2007Novartis Foundation symposium23 citations

   Semantic Scholar

   Save

9. Determinants governing the potency of STAT3 activation via the individual STAT3-recruiting motifs of gp130.

   U. Lehmann, U. Sommer, Tanya Smyczek, Michael Hörtner +5 more

   2006Cellular Signalling19 citations

   Semantic Scholar

   Save

10. Rasip 1 regulates vertebrate vascular endothelial junction stability through Epac 1-Rap 1 signaling

    Christopher W. Wilson, Leon H. Parker, Christopher J. Hall, Tanya Smyczek +12 more

    20139 citations

    Semantic Scholar

    Save

11. Abstract 3295: Inhibiting vascular morphogenesis in tumors: EGFL7 as a novel therapeutic target

    Stacey Yeung, Tanya Smyczek, Jason H. Cheng, A. Lima +15 more

    20115 citations

    Semantic Scholar

    Save

12. Abstract 3284: Preclinical and clinical evaluation of pharmacodynamic biomarkers of a novel anti-angiogenesis agent, anti-EGFL7

    M. Huseni, L. Rosen, M. Gordon, P. Munster +8 more

    20110 citations

    Semantic Scholar

    Save

13. Role of EGFL7 during blood vessel formation and remodelling

    Maike Schmidt, Tanya Smyczek, Wei-Lan Ye

    20060 citations

    Semantic Scholar

    Save