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S. Bröer · SciRah

Researcher profile · Semantic Scholar

S. Bröer

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S. Bröer — researcher profile on SciRah

h-index: 70
Works: 260
Citations: 16K

Most-cited papers

Amino acid homeostasis and signalling in mammalian cells and organisms
S. Bröer, A. Bröer
2017Biochemical Journal434 citations Open access
Semantic Scholar
Deletion of Amino Acid Transporter ASCT2 (SLC1A5) Reveals an Essential Role for Transporters SNAT1 (SLC38A1) and SNAT2 (SLC38A2) to Sustain Glutaminolysis in Cancer Cells*
A. Bröer, F. Rahimi, S. Bröer
2016Journal of Biological Chemistry231 citations Open access
Semantic Scholar
THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Transporters
Stephen P. H. Alexander, E. Kelly, A. Mathie, J. A. Peters +19 more
2019British Journal of Pharmacology224 citations Open access
Semantic Scholar
The SLC38 family of sodium–amino acid co-transporters
S. Bröer
2013Pflügers Archiv: European Journal of Physiology221 citations
Semantic Scholar
The Concise Guide to PHARMACOLOGY 2023/24: Transporters
Stephen P. H. Alexander, Doriano Fabbro, E. Kelly, A. Mathie +24 more
2023British Journal of Pharmacology168 citations Open access
Semantic Scholar
Amino acid metabolism, transport and signalling in the liver revisited.
C. Paulusma, W. Lamers, S. Bröer, S. V. D. van de Graaf
2022Biochemical Pharmacology161 citations Open access
Semantic Scholar
THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Transporters
Stephen P. H. Alexander, E. Kelly, A. Mathie, J. A. Peters +20 more
2021British Journal of Pharmacology151 citations Open access
Semantic Scholar
Amino Acid Transport Across the Mammalian Intestine
S. Bröer, Stephen J. Fairweather
2018Comprehensive Physiology138 citations
Semantic Scholar
A Self-defeating Anabolic Program Leads to β-Cell Apoptosis in Endoplasmic Reticulum Stress-induced Diabetes via Regulation of Amino Acid Flux*
Dawid Krokowski, Jaeseok Han, Mridusmita Saikia, Mithu Majumder +15 more
2013Journal of Biological Chemistry116 citations Open access
Semantic Scholar
Disruption of Amino Acid Homeostasis by Novel ASCT2 Inhibitors Involves Multiple Targets
A. Bröer, Stephen J. Fairweather, S. Bröer
2018Frontiers in Pharmacology111 citations Open access
Semantic Scholar
Quantitative modelling of amino acid transport and homeostasis in mammalian cells
Gregory Gauthier-Coles, Jade Vennitti, Zhiduo Zhang, William C. Comb +4 more
2021Nature Communications103 citations Open access
Semantic Scholar
Restriction of essential amino acids dictates the systemic metabolic response to dietary protein dilution
Y. Yap, Patricia M. Rusu, Andrea Y. Chan, B. Fam +16 more
2020Nature Communications103 citations Open access
Semantic Scholar
Creatine as a booster for human brain function. How might it work?
C. Rae, S. Bröer
2015Neurochemistry International98 citations
Semantic Scholar
Intestinal Amino Acid Transport and Metabolic Health.
S. Bröer
2023Annual review of nutrition89 citations Open access
Semantic Scholar
Amino Acid Transporters as Targets for Cancer Therapy: Why, Where, When, and How
S. Bröer
2020International Journal of Molecular Sciences86 citations Open access
Semantic Scholar
Ablation of the ASCT2 (SLC1A5) gene encoding a neutral amino acid transporter reveals transporter plasticity and redundancy in cancer cells
A. Bröer, Gregory Gauthier-Coles, F. Rahimi, M. van Geldermalsen +4 more
2019Journal of Biological Chemistry82 citations Open access
Semantic Scholar
Metabolism, Compartmentation, Transport and Production of Acetate in the Cortical Brain Tissue Slice
C. Rae, A. Fekete, M. Kashem, F. Nasrallah +1 more
2012Neurochemical Research82 citations
Semantic Scholar
Mice lacking neutral amino acid transporter B0AT1 (Slc6a19) have elevated levels of FGF21 and GLP-1 and improved glycaemic control
Yang Jiang, A. Rose, T. Sijmonsma, A. Bröer +4 more
2015Molecular Metabolism75 citations Open access
Semantic Scholar
Amino Acid Homeostasis in Mammalian Cells with a Focus on Amino Acid Transport
S. Bröer, Gregory Gauthier-Coles
2021Journal of NutriLife70 citations Open access
Semantic Scholar
Intestinal peptidases form functional complexes with the neutral amino acid transporter B0AT1
Stephen J. Fairweather, A. Bröer, M. O'Mara, S. Bröer
2012Biochemical Journal67 citations Open access
Semantic Scholar
Cationic amino acid transporters play key roles in the survival and transmission of apicomplexan parasites
Esther Rajendran, Sanduni V. Hapuarachchi, Catherine M. Miller, Stephen J. Fairweather +6 more
2017Nature Communications66 citations Open access
Semantic Scholar
Mice Deficient in the Putative Phospholipid Flippase ATP11C Exhibit Altered Erythrocyte Shape, Anemia, and Reduced Erythrocyte Life Span*♦
M. Yabas, L. Coupland, D. Cromer, M. Winterberg +6 more
2014Journal of Biological Chemistry64 citations Open access
Semantic Scholar
Amino acid transporters as modulators of glucose homeostasis.
S. Bröer
2021Trends in endocrinology and metabolism54 citations Open access
Semantic Scholar
Loss of function mutation of the Slc38a3 glutamine transporter reveals its critical role for amino acid metabolism in the liver, brain, and kidney
Kessara Chan, S. Busque, M. Sailer, C. Stoeger +4 more
2016Pflügers Archiv: European Journal of Physiology52 citations Open access
Semantic Scholar
The tyrosine transporter of Toxoplasma gondii is a member of the newly defined apicomplexan amino acid transporter (ApiAT) family
K. Parker, Stephen J. Fairweather, Esther Rajendran, M. Blume +4 more
2019PLoS Pathogens49 citations Open access
Semantic Scholar
Molecular Basis for the Interaction of the Mammalian Amino Acid Transporters B0AT1 and B0AT3 with Their Ancillary Protein Collectrin*
Stephen J. Fairweather, A. Bröer, Nandhitha Subramanian, E. Tumer +4 more
2015Journal of Biological Chemistry48 citations Open access
Semantic Scholar
Identification of novel inhibitors of the amino acid transporter B0AT1 (SLC6A19), a potential target to induce protein restriction and to treat type 2 diabetes
Qi Cheng, Nishank Shah, A. Bröer, Stephen J. Fairweather +4 more
2017British Journal of Pharmacology47 citations Open access
Semantic Scholar
Deletion Syndrome
Dieter Metze, Tam Nguyen, B. Haack, A. Leung +59 more
201944 citations
Semantic Scholar
ASCT2 (SLC1A5)-Deficient Mice Have Normal B-Cell Development, Proliferation, and Antibody Production
E. Masle-Farquhar, A. Bröer, M. Yabas, A. Enders +1 more
2017Frontiers in Immunology41 citations Open access
Semantic Scholar
SNAT3‐mediated glutamine transport in perisynaptic astrocytes in situ is regulated by intracellular sodium
Alison C. Todd, M. Marx, Sarah R. Hulme, S. Bröer +1 more
2017Glia40 citations
Semantic Scholar
Amino Acid Transporters as Disease Modifiers and Drug Targets
S. Bröer
2018SLAS discovery : advancing life sciences R & D39 citations Open access
Semantic Scholar
Novel Chemical Scaffolds to Inhibit the Neutral Amino Acid Transporter B0AT1 (SLC6A19), a Potential Target to Treat Metabolic Diseases
Aditya Yadav, Nishank Shah, P. Tiwari, Kiran Javed +3 more
2020Frontiers in Pharmacology32 citations Open access
Semantic Scholar
Heteromeric Solute Carriers: Function, Structure, Pathology and Pharmacology.
Stephen J. Fairweather, Nishank Shah, S. Bröer
2020Advances in Experimental Medicine and Biology29 citations
Semantic Scholar
Automated Production of Human Induced Pluripotent Stem Cell-Derived Cortical and Dopaminergic Neurons with Integrated Live-Cell Monitoring.
A. Dhingra, Joachim Täger, E. Bressan, S. Rodríguez-Nieto +7 more
2020Journal of Visualized Experiments29 citations Open access
Semantic Scholar
Mice Lacking the Intestinal and Renal Neutral Amino Acid Transporter SLC6A19 Demonstrate the Relationship between Dietary Protein Intake and Amino Acid Malabsorption
Kiran Javed, S. Bröer
2019Nutrients29 citations Open access
Semantic Scholar
Enterocyte-specific Regulation of the Apical Nutrient Transporter SLC6A19 (B0AT1) by Transcriptional and Epigenetic Networks*
Emrah Tümer, A. Bröer, Sarojini Balkrishna, Torsten Jülich +1 more
2013Journal of Biological Chemistry28 citations Open access
Semantic Scholar
Breakdown in membrane asymmetry regulation leads to monocyte recognition of P. falciparum-infected red blood cells
M. Fraser, Weidong Jing, S. Bröer, F. Kurth +3 more
2021PLoS Pathogens25 citations Open access
Semantic Scholar
Maternal heterozygosity of Slc6a19 causes metabolic perturbation and congenital NAD deficiency disorder in mice
H. Cuny, Kayleigh Bozon, Rosemary B. Kirk, Delicia Z. Sheng +2 more
2022Disease Models & Mechanisms23 citations Open access
Semantic Scholar
A GC-MS/Single-Cell Method to Evaluate Membrane Transporter Substrate Specificity and Signaling
Stephen J. Fairweather, Shoko Okada, Gregory Gauthier-Coles, Kiran Javed +2 more
2021Frontiers in Molecular Biosciences23 citations Open access
Semantic Scholar
ATP11C Facilitates Phospholipid Translocation across the Plasma Membrane of All Leukocytes
M. Yabas, Weidong Jing, S. Shafik, S. Bröer +1 more
2016PLoS ONE23 citations Open access
Semantic Scholar
Aristolochic acid-induced nephropathy is attenuated in mice lacking the neutral amino acid transporter B0AT1 (Slc6a19).
Aleix Navarro-Garrido, Young Chul Kim, Yuji Oe, Hai-Yan Zhang +6 more
2022AJP - Renal Physiology21 citations Open access
Semantic Scholar
Coordinated action of multiple transporters in the acquisition of essential cationic amino acids by the intracellular parasite Toxoplasma gondii
Stephen J. Fairweather, Esther Rajendran, M. Blume, Kiran Javed +5 more
2021bioRxiv21 citations Open access
Semantic Scholar
Development of Biomarkers for Inhibition of SLC6A19 (B0AT1)—A Potential Target to Treat Metabolic Disorders
Kiran Javed, Qi Cheng, A. Carroll, Thy T. Truong +1 more
2018International Journal of Molecular Sciences21 citations Open access
Semantic Scholar
Loss of Functional Endothelial Connexin40 Results in Exercise-Induced Hypertension in Mice
S. K. Morton, D. Chaston, Lauren Howitt, Jillian M. Heisler +6 more
2015HYPERTENSION19 citations Open access
Semantic Scholar
Molecular basis of inhibition of the amino acid transporter B0AT1 (SLC6A19)
Jun-Yang Xu, Ziwei Hu, Lu Dai, Aditya Yadav +6 more
2024bioRxiv14 citations Open access
Semantic Scholar
Cryo-EM structure of the human Asc-1 transporter complex
Ya-Ning Li, Yingying Guo, A. Bröer, Lu Dai +2 more
2024Nature Communications14 citations Open access
Semantic Scholar
Calpain cleaves phospholipid flippase ATP8A1 during apoptosis in platelets.
Weidong Jing, M. Yabas, A. Bröer, Lucy A. Coupland +3 more
2019Blood Advances14 citations Open access
Semantic Scholar
Expression of Glutamine Transporter Slc38a3 (SNAT3) During Acidosis is Mediated by a Different Mechanism than Tissue-Specific Expression
Sarojini Balkrishna, A. Bröer, S. Welford, M. Hatzoglou +1 more
2014Cellular Physiology and Biochemistry14 citations Open access
Semantic Scholar
SAL1‐PAP retrograde signaling orchestrates photosynthetic and extracellular reactive oxygen species for stress responses
E. Tee, Stephen J. Fairweather, Hanh M. Vo, Chenchen Zhao +10 more
2025The Plant Journal13 citations Open access
Semantic Scholar
Epithelial neutral amino acid transporters: lessons from mouse models
S. Bröer
2013Current opinion in nephrology and hypertension13 citations
Semantic Scholar

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