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M. Kashem · SciRah

Researcher profile · Semantic Scholar

M. Kashem

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M. Kashem — researcher profile on SciRah

h-index: 33
Works: 160
Citations: 3,182

Most-cited papers

Adolescent Rats Find Repeated Δ9-THC Less Aversive Than Adult Rats but Display Greater Residual Cognitive Deficits and Changes in Hippocampal Protein Expression Following Exposure
Heidi R Quinn, I. Matsumoto, P. Callaghan, Leonora E. Long +9 more
2008Neuropsychopharmacology300 citations
Semantic Scholar
Identification of pharmacological inhibitors of the MEK5/ERK5 pathway.
R. Tatake, M. M. O'Neill, C. Kennedy, A. Wayne +6 more
2008Biochemical and Biophysical Research Communications - BBRC165 citations
Semantic Scholar
Three Mechanistically Distinct Kinase Assays Compared: Measurement of Intrinsic ATPase Activity Identified the Most Comprehensive Set of ITK Inhibitors
M. Kashem, R. Nelson, J. Yingling, S. Pullen +8 more
2007Journal of biomolecular screening128 citations Open access
Semantic Scholar
Relationship of visit-to-visit and ambulatory blood pressure variability to vascular function in African Americans
Keith M. Diaz, P. Veerabhadrappa, M. Kashem, Deborah L. Feairheller +4 more
2011Hypertension Research126 citations Open access
Semantic Scholar
Managing hypertension in urban underserved subjects using telemedicine--a clinical trial.
A. Bové, C. Homko, W. Santamore, M. Kashem +2 more
2013American Heart Journal88 citations
Semantic Scholar
Metabolism, Compartmentation, Transport and Production of Acetate in the Cortical Brain Tissue Slice
C. Rae, A. Fekete, M. Kashem, F. Nasrallah +1 more
2012Neurochemical Research82 citations
Semantic Scholar
VISIT-TO-VISIT AND 24-H BLOOD PRESSURE VARIABILITY: ASSOCIATION WITH ENDOTHELIAL AND SMOOTH MUSCLE FUNCTION IN AFRICAN AMERICANS
Keith M. Diaz, P. Veerabhadrappa, M. Kashem, Sunny R. Thakkar +12 more
2013Journal of Human Hypertension73 citations Open access
Semantic Scholar
Hit to lead account of the discovery of a new class of inhibitors of Pim kinases and crystallographic studies revealing an unusual kinase binding mode.
K. Qian, Lian Wang, C. Cywin, B. Farmer +15 more
2009Journal of Medicinal Chemistry65 citations Open access
Semantic Scholar
Endothelial Activation Microparticles and Inflammation Status Improve with Exercise Training in African Americans
D. Babbitt, Keith M. Diaz, Deborah L. Feairheller, K. Sturgeon +11 more
2013International Journal of Hypertension54 citations Open access
Semantic Scholar
GLAST But Not Least—Distribution, Function, Genetics and Epigenetics of l-Glutamate Transport in Brain—Focus on GLAST/EAAT1
O. Šerý, N. Sultana, M. Kashem, D. Pow +1 more
2015Neurochemical Research51 citations
Semantic Scholar
Pyrazinoindolone inhibitors of MAPKAP-K2.
D. Goldberg, Y. Choi, D. Cogan, M. Corson +20 more
2008Bioorganic & Medicinal Chemistry Letters50 citations Open access
Semantic Scholar
Anterior Leaflet Augmentation With CorMatrix Porcine Extracellular Matrix in Twenty-Five Patients: Unexpected Patch Failures and Histologic Analysis.
Thomas M. Kelley, M. Kashem, He Wang, James R. McCarthy +3 more
2017Annals of Thoracic Surgery49 citations Open access
Semantic Scholar
Proteomic analysis demonstrates adolescent vulnerability to lasting hippocampal changes following chronic alcohol consumption.
Garth A. Hargreaves, Heidi R Quinn, M. Kashem, I. Matsumoto +1 more
2009Alcoholism: Clinical and Experimental Research47 citations
Semantic Scholar
Effects of Moderate Aerobic Exercise Training on Vascular Health and Blood Pressure in African Americans
Deborah L. Feairheller, Keith M. Diaz, M. Kashem, Sunny R. Thakkar +12 more
2014The Journal of Clinical Hypertension44 citations Open access
Semantic Scholar
5-Aminomethylbenzimidazoles as potent ITK antagonists.
Doris Riether, Renee M. Zindell, J. Kowalski, B. Cook +18 more
2009Bioorganic & Medicinal Chemistry Letters41 citations Open access
Semantic Scholar
Proteomic analysis of hearts from frataxin knockout mice: Marked rearrangement of energy metabolism, a response to cellular stress and altered expression of proteins involved in cell structure, motility and metabolism
Robert Sutak, Xiangcong Xu, Megan Whitnall, M. Kashem +2 more
2008Proteomics41 citations
Semantic Scholar
CO2 Emissions and Development Indicators: a Causality Analysis for Bangladesh
M. Kashem, M. Rahman
2019Environmental Processes39 citations
Semantic Scholar
Substituted 2H-isoquinolin-1-ones as potent Rho-kinase inhibitors: part 3, aryl substituted pyrrolidines.
T. Bosanac, E. Hickey, J. Ginn, M. Kashem +6 more
2010Bioorganic & Medicinal Chemistry Letters39 citations Open access
Semantic Scholar
Differential protein expression in the corpus callosum (genu) of human alcoholics.
M. Kashem, C. Harper, I. Matsumoto
2008Neurochemistry International37 citations
Semantic Scholar
Novel molecular changes induced by Nrg1 hypomorphism and Nrg1-cannabinoid interaction in adolescence: a hippocampal proteomic study in mice
Jarrah R. Spencer, K. Darbyshire, A. Boucher, M. Kashem +4 more
2013Frontiers in Cellular Neuroscience36 citations Open access
Semantic Scholar
Discovery of potent inhibitors of interleukin-2 inducible T-cell kinase (ITK) through structure-based drug design.
B. Cook, Jörg Bentzien, A. White, P. Nemoto +11 more
2009Bioorganic & Medicinal Chemistry Letters33 citations Open access
Semantic Scholar
Long-term daily access to alcohol alters dopamine-related synthesis and signaling proteins in the rat striatum.
M. Kashem, Selina Ahmed, R. Sarker, E. U. Ahmed +2 more
2012Neurochemistry International32 citations
Semantic Scholar
Hospitalized Acute Exacerbation of COPD Impairs Flow and Nitroglycerin-Mediated Peripheral Vascular Dilation
N. Marchetti, D. Ciccolella, M. Jacobs, Aaron Crookshank +4 more
2011COPD32 citations Open access
Semantic Scholar
Neuroadaptations in the Striatal Proteome of the Rat Following Prolonged Excessive Sucrose Intake
Selina Ahmed, M. Kashem, R. Sarker, E. U. Ahmed +2 more
2014Neurochemical Research31 citations
Semantic Scholar
An intestinal microRNA modulates the homeostatic adaptation to chronic oxidative stress in C. elegans
M. Kato, M. Kashem, Chao Cheng
2016Aging30 citations Open access
Semantic Scholar
Indole RSK inhibitors. Part 1: discovery and initial SAR.
S. Boyer, J. Burke, Xin Guo, T. Kirrane +15 more
2012Bioorganic & Medicinal Chemistry Letters29 citations Open access
Semantic Scholar
Indole RSK inhibitors. Part 2: optimization of cell potency and kinase selectivity.
T. Kirrane, S. Boyer, J. Burke, Xin Guo +8 more
2012Bioorganic & Medicinal Chemistry Letters27 citations Open access
Semantic Scholar
The discovery of thienopyridine analogues as potent IkappaB kinase beta inhibitors. Part II.
Jiang-Ping Wu, R. Fleck, J. Brickwood, A. Capolino +27 more
2009Bioorganic & Medicinal Chemistry Letters27 citations Open access
Semantic Scholar
Discovery, SAR and X-ray structure of 1H-benzimidazole-5-carboxylic acid cyclohexyl-methyl-amides as inhibitors of inducible T-cell kinase (Itk).
K. J. Moriarty, Hidenori Takahashi, S. Pullen, Hnin Hnin Khine +20 more
2008Bioorganic & Medicinal Chemistry Letters27 citations Open access
Semantic Scholar
Ethanol, not metabolized in brain, significantly reduces brain metabolism, probably via specific GABA(A) receptors
C. Rae, Joanne E Davidson, A. D. Maher, Benjamin D. Rowlands +5 more
2013Journal of Neurochemistry26 citations Open access
Semantic Scholar
Itk kinase inhibitors: initial efforts to improve the metabolical stability and the cell activity of the benzimidazole lead.
K. J. Moriarty, Michael P. Winters, L. Qiao, D. Ryan +13 more
2008Bioorganic & Medicinal Chemistry Letters26 citations Open access
Semantic Scholar
Hippocampal protein expression is differentially affected by chronic paroxetine treatment in adolescent and adult rats: a possible mechanism of “paradoxical” antidepressant responses in young persons
Emily A. Karanges, M. Kashem, R. Sarker, E. U. Ahmed +4 more
2013Frontiers in Pharmacology24 citations Open access
Semantic Scholar
Metabolomics of Neurotransmitters and Related Metabolites in Post-Mortem Tissue from the Dorsal and Ventral Striatum of Alcoholic Human Brain
M. Kashem, Selina Ahmed, N. Sultana, E. U. Ahmed +5 more
2016Neurochemical Research23 citations
Semantic Scholar
A long hangover from party drugs: residual proteomic changes in the hippocampus of rats 8 weeks after γ-hydroxybutyrate (GHB), 3,4-methylenedioxymethamphetamine (MDMA) or their combination.
P. V. van Nieuwenhuijzen, M. Kashem, I. Matsumoto, G. Hunt +1 more
2010Neurochemistry International23 citations
Semantic Scholar
BI 1002494, a Novel Potent and Selective Oral Spleen Tyrosine Kinase Inhibitor, Displays Differential Potency in Human Basophils and B Cells
D. Lamb, S. Wollin, A. Schnapp, D. Bischoff +26 more
2016Journal of Pharmacology and Experimental Therapeutics22 citations Open access
Semantic Scholar
Substituted 2H-isoquinolin-1-ones as potent Rho-kinase inhibitors: part 2, optimization for blood pressure reduction in spontaneously hypertensive rats.
J. Ginn, T. Bosanac, Rhonda Chen, C. Cywin +11 more
2010Bioorganic & Medicinal Chemistry Letters21 citations Open access
Semantic Scholar
2-Aminobenzimidazoles as potent ITK antagonists: trans-stilbene-like moieties targeting the kinase specificity pocket.
Ho-Yin Lo, Jörg Bentzien, R. Fleck, S. Pullen +5 more
2008Bioorganic & Medicinal Chemistry Letters21 citations Open access
Semantic Scholar
Differential protein expression in the corpus callosum (body) of human alcoholic brain
M. Kashem, Huyghues Des Etages, N. Kopitar-Jerala, I. McGregor +1 more
2009Journal of Neurochemistry20 citations
Semantic Scholar
Antipsychotic Induced Alteration of Growth and Proteome of Rat Neural Stem Cells
E. U. Ahmed, Selina Ahmed, W. Ukai, I. Matsumoto +3 more
2012Neurochemical Research19 citations
Semantic Scholar
2-Aminobenzimidazoles as potent ITK antagonists: de novo design of a pyrrole system targeting additional hydrogen bonding interaction
Ho-Yin Lo, Jörg Bentzien, A. White, Chuk C. Man +9 more
200819 citations
Semantic Scholar
Effects of typical (haloperidol) and atypical (risperidone) antipsychotic agents on protein expression in rat neural stem cells.
M. Kashem, Rahnuma Ummehany, W. Ukai, E. Hashimoto +3 more
2009Neurochemistry International18 citations
Semantic Scholar
Substituted 2H-isoquinolin-1-one as potent Rho-Kinase inhibitors. Part 1: Hit-to-lead account.
Frank Wu, Frank H. Büttner, Rhonda Chen, E. Hickey +11 more
2010Bioorganic & Medicinal Chemistry Letters17 citations Open access
Semantic Scholar
A standardized exercise intervention differentially affects pre- and post-menopausal African American women
Jan Kretzschmar, D. Babbitt, Keith M. Diaz, Deborah L. Feairheller +11 more
2014Menopause16 citations Open access
Semantic Scholar
Actions of alcohol in brain: Genetics, Metabolomics, GABA receptors, Proteomics and Glutamate Transporter GLAST/EAAT1.
M. Kashem, O. Šerý, D. Pow, Benjamin D. Rowlands +2 more
2020Current Molecular Pharmacology14 citations
Semantic Scholar
GLAST (GLutamate and ASpartate Transporter) in human prefrontal cortex; interactome in healthy brains and the expression of GLAST in brains of chronic alcoholics
M. Kashem, N. Sultana, D. Pow, V. Balcar
2019Neurochemistry International14 citations
Semantic Scholar
Comparative proteomics in the corpus callosal sub-regions of postmortem human brain.
M. Kashem, R. Sarker, H. Des Etages, R. Machaalani +3 more
2009Neurochemistry International14 citations
Semantic Scholar
Hit to lead account of the discovery of bisbenzamide and related ureidobenzamide inhibitors of Rho kinase.
T. Morwick, Frank H. Büttner, C. Cywin, G. Dahmann +12 more
2010Journal of Medicinal Chemistry13 citations Open access
Semantic Scholar
Environmental Proteomics: Extraction and Identification of Protein in Soil
Z. Solaiman, M. Kashem, I. Matsumoto
200713 citations
Semantic Scholar
Prior and peri-operative revascularization does not affect survival in lung transplant patients.
J. Kanaparthi, M. Kashem, M. Suryapalam, Hua-Qing Zhao +6 more
2020Annals of Thoracic Surgery12 citations Open access
Semantic Scholar
A High-Throughput Scintillation Proximity Assay for Sphingosine-1-Phosphate Lyase
M. Kashem, Chunling Wa, J. Wolak, Nicholas S. Grafos +10 more
2014Assay and drug development technologies12 citations
Semantic Scholar

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